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G46677TE

Summary

GlyTouCan ID: G46677TE
IUPAC Condensed: Neu5Ac(a2-3)[Neu5Ac(a2-3)Gal(b1-3)GalNAc(b1-4)]Gal(b1-4)Glc(b1-
Motifs: GD1a
Subsumption Level: Fully-defined saccharide
Monoisotopic Mass: 1289.44

External Links

GlyGen

G46677TE

ChEBI

59209

PubChem Compound

45266861

PubChem Substance

252282546

3D Structures

GLYCAM: Neup5Aca2-3[Neup5Aca2-3DGalpb1-3DGalpNAcb1-4]DGalpb1-4DGlcpb1-OH

GlycoShape

G46677TE

Displaying 1 entry
Archetype	α	β
G21518JT	G01633SK	G46677TE

Organisms

Displaying entries **16 - 20** of 20 in total

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Organisms	Evidence
Sus scrofa (pig)	GlyTouCan(glycome-db)
Papio hamadryas (hamadryas baboon)	GlyTouCan(glycome-db)
Oryctolagus cuniculus (rabbit)	GlyTouCan(glycome-db)
Chinchillidae (chinchillas)	GlyTouCan(glycome-db)
Parophrys vetulus (English sole)	GlyTouCan(glycome-db)

Taxonomic Hierarchy

root

cellular organisms [inference]

Eukaryota (eucaryotes) [inference]

Opisthokonta [inference]

Metazoa (metazoans) [inference]

Eumetazoa [inference]

Bilateria [inference]

Deuterostomia [inference]

Chordata (chordates) [inference]

Craniata [inference]

Vertebrata (vertebrates) [inference]

Gnathostomata (jawed vertebrates) [inference]

Teleostomi [inference]

Euteleostomi (bony vertebrates) [inference]

Actinopterygii (ray-finned fishes) [inference]

Actinopteri [inference]

Neopterygii [inference]

Teleostei (teleost fishes) [inference]

Osteoglossocephalai [inference]

Clupeocephala [inference]

Euteleosteomorpha [inference]

Protacanthopterygii [inference]

Salmoniformes (salmons and trouts) [inference]

Salmonidae (salmonids) [inference]

Salmoninae (trouts, salmons & chars) [inference]

Oncorhynchus [inference]

Oncorhynchus mykiss (rainbow trout)

Neoteleostei [inference]

Eurypterygia [inference]

Ctenosquamata [inference]

Acanthomorphata [inference]

Euacanthomorphacea [inference]

Percomorphaceae [inference]

Carangaria [inference]

Pleuronectiformes (flatfishes) [inference]

Pleuronectoidei [inference]

Pleuronectidae (righteye flounders) [inference]

Parophrys [inference]

Parophrys vetulus (English sole)

Ovalentaria [inference]

Cichlomorphae [inference]

Cichliformes (cichlids and convict blennies) [inference]

Cichlidae (cichlids)

Otomorpha [inference]

Ostariophysi [inference]

Otophysi [inference]

Cypriniphysae [inference]

Cypriniformes (carps and others) [inference]

Cyprinoidei [inference]

Cyprinidae [inference]

Cyprininae [inference]

Carassius [inference]

Carassius auratus (goldfish)

Sarcopterygii [inference]

Dipnotetrapodomorpha [inference]

Tetrapoda (tetrapods) [inference]

Amniota (amniotes) [inference]

Sauropsida (sauropsids) [inference]

Sauria (diapsids) [inference]

Archelosauria [inference]

Archosauria [inference]

Dinosauria [inference]

Saurischia [inference]

Theropoda [inference]

Coelurosauria [inference]

Aves (birds) [inference]

Neognathae [inference]

Galloanserae [inference]

Galliformes (landfowls) [inference]

Phasianidae (turkeys) [inference]

Meleagridinae [inference]

Meleagris [inference]

Meleagris gallopavo (turkey)

Phasianinae [inference]

Gallus [inference]

Gallus gallus (chicken)

Mammalia (mammals) [inference]

Theria [inference]

Eutheria (placentals) [inference]

Boreoeutheria [inference]

Laurasiatheria [inference]

Artiodactyla (even-toed ungulates & whales) [inference]

Ruminantia [inference]

Pecora [inference]

Bovidae [inference]

Bovinae [inference]

Bos (cattle) [inference]

Bos taurus (domestic cattle)

Suina [inference]

Suidae (pigs) [inference]

Sus [inference]

Sus scrofa (pig)

Whippomorpha [inference]

Cetacea (whales) [inference]

Odontoceti (tooth whales) [inference]

Delphinidae (marine dolphins) [inference]

Tursiops [inference]

Tursiops truncatus (common bottlenose dolphin)

Carnivora (carnivores) [inference]

Feliformia [inference]

Felidae (cat family) [inference]

Felinae [inference]

Felis [inference]

Felis catus (domestic cat)

Eulipotyphla (hedgehogs, shrews, moles and others) [inference]

Soricidae (shrews)

Euarchontoglires [inference]

Glires (Rodents and rabbits) [inference]

Rodentia (rodent) [inference]

Myomorpha (mice and others) [inference]

Muroidea [inference]

Muridae [inference]

Murinae [inference]

Rattus

Mus (mice) [inference]

Mus [inference]

Mus musculus (house mouse)

Cricetidae [inference]

Cricetinae (hamsters)

Cricetulus [inference]

Cricetulus griseus (Chinese hamster)

Hystricomorpha (guinea pigs and others) [inference]

Chinchillidae (chinchillas)

Lagomorpha [inference]

Leporidae (rabbits and hares) [inference]

Oryctolagus [inference]

Oryctolagus cuniculus (rabbit)

Primates [inference]

Haplorrhini [inference]

Simiiformes [inference]

Catarrhini [inference]

Cercopithecoidea [inference]

Cercopithecidae (Old World monkeys) [inference]

Cercopithecinae [inference]

Papio (baboons) [inference]

Papio hamadryas (hamadryas baboon)

Hominoidea (apes) [inference]

Hominidae (great apes) [inference]

Homininae [inference]

Homo [inference]

Homo sapiens (human)

Discoba [inference]

Euglenozoa [inference]

Kinetoplastea (kinetoplasts) [inference]

Metakinetoplastina [inference]

Trypanosomatida [inference]

Trypanosomatidae [inference]

Leishmaniinae [inference]

Leishmania [inference]

Leishmania mexicana species complex [inference]

Leishmania amazonensis

GlycoGene Database (GGDB)

Displaying 1 entry
Gene Symbol	Donor	Acceptor	Reducing terminal(Acceptor)	Product	Reducing terminal(Product)	Reference
ST8SIA5	CMP-Neu5Ac	G46677TE	Cer	G68110IF	Cer	8910600

Displaying entries **1 - 5** of 6 in total

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Gene Symbol	Donor	Acceptor	Reducing terminal(Acceptor)	Product	Reducing terminal(Product)	Reference
ST8SIA1	CMP-Neu5Ac	G46677TE	Cer	G68110IF	Cer	8910600
ST3GAL2	CMP-Neu5Ac	G48558GR	Cer	G46677TE	Cer	8920913
ST8SIA5	CMP-Neu5Ac	G46677TE	Cer	G40183QN	Cer	9199191
ST8SIA6	CMP-Neu5Ac	G46677TE	Cer	G40183QN	Cer	11980897 16120058
ST3GAL1	CMP-Neu5Ac	G48558GR	ceramide	G46677TE	ceramide	8027041

Displaying entries **1 - 5** of 6 in total

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Gene Symbol	Donor	Acceptor	Reducing terminal(Acceptor)	Reference
ST6GALNAC4	CMP-Neu5Ac	G46677TE	ceramide	11062056
ST3GAL6	CMP-Neu5Ac	G46677TE	ceramide	10206952
ST8SIA2	CMP-Neu5Ac	G46677TE	Cer	7782326
ST8SIA3	CMP-Neu5Ac	G46677TE	Cer	7782326 8910600
ST6GALNAC2	CMP-Neu5Ac	G46677TE	ceramide	11062056

KEGG BRITE Database

KEGG ID

G00111

Enzyme

References

Reactions

Displaying **all 3** entries
KEGG Reaction	Enzyme	Acceptor	Product
R05942	2.4.3.2	G48558GR	G46677TE
R05945		G46677TE	G02149VR
R05943	2.4.99.-	G46677TE	G68110IF

GlycoEpitope

Epitope ID: EP0056

Sequence Descriptors

GlycoCT

RES
1b:b-dglc-HEX-1:5
2b:b-dgal-HEX-1:5
3b:a-dgro-dgal-NON-2:6|1:a|2:keto|3:d
4s:n-acetyl
5b:b-dgal-HEX-1:5
6s:n-acetyl
7b:b-dgal-HEX-1:5
8b:a-dgro-dgal-NON-2:6|1:a|2:keto|3:d
9s:n-acetyl
LIN
1:1o(4+1)2d
2:2o(3+2)3d
3:3d(5+1)4n
4:2o(4+1)5d
5:5d(2+1)6n
6:5o(3+1)7d
7:7o(3+2)8d
8:8d(5+1)9n

WURCS

WURCS=2.0/4,6,5/[a2122h-1b_1-5][a2112h-1b_1-5][Aad21122h-2a_2-6_5*NCC/3=O][a2112h-1b_1-5_2*NCC/3=O]/1-2-3-4-2-3/a4-b1_b3-c2_b4-d1_d3-e1_e3-f2

Literature

Displaying entries **21 - 30** of 45 in total

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PubMed ID	Title	First Author	Publication Date	Source
11062056	Cloning, expression and gene organization of a human Neu5Ac alpha 2-3Gal beta 1-3GalNAc alpha 2,6-sialyltransferase: hST6GalNAcIV	Harduin-Lepers A	2000 Nov 15	PubChem
10854286	High-affinity anti-ganglioside IgG antibodies raised in complex ganglioside knockout mice: reexamination of GD1a immunolocalization	Lunn MP	2000 Jul	GlyGen GlycoEpitope
10206952	Molecular cloning of a novel alpha2,3-sialyltransferase (ST3Gal VI) that sialylates type II lactosamine structures on glycoproteins and glycolipids	Okajima T	1999 Apr 23	PubChem
9673245	Lipopolysaccharides from Campylobacter jejuni O:41 Strains Associated with Guillain-Barré Syndrome Exhibit Mimicry of GM 1 Ganglioside	Prendergast MM	1998 Aug	PubChem
9710005	Campylobacter jejuni lipopolysaccharides in Guillain-Barré syndrome: molecular mimicry and host susceptibility	Sheikh KA	1998 Aug	PubChem
9317004	Serum antibodies against gangliosides and Campylobacter jejuni lipopolysaccharides in Miller Fisher syndrome	Neisser A	1997 Oct	PubChem
9065554	Motor nerve terminal degeneration provides a potential mechanism for rapid recovery in acute motor axonal neuropathy after campylobacter infection	Ho TW	1997 Mar	PubChem
9199191	Molecular cloning and expression of human alpha2,8-sialyltransferase (hST8Sia V)	Kim YJ	1997 Jun 18	PubChem
9119976	Close association of Guillain-Barré syndrome with antibodies to minor monosialogangliosides GM1b and GM1 alpha	Yuki N	1997 Apr	PubChem
8891271	Immunocytochemical analysis of gangliosides in rat primary cerebellar cultures using specific monoclonal antibodies	Kawashima I	1996 Sep 02	GlyGen GlycoEpitope

PubAnnotation

Displaying entries **6 - 10** of 10 in total

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Title	Authors	Source	Publication Date	PubMed ID
The role of gangliosides in the interaction of human chorionic gonadotropin and cholera toxin with murine Leydig tumor cells.	Fishman PH Bradley RM Rebois RV Brady RO	J Biol Chem	1984 Jun 25	6330091
Galactose oxidase action on GM1 ganglioside in micellar and vesicular dispersions.	Masserini M Sonnino S Ghidoni R Chigorno V Tettamanti G	Biochim Biophys Acta	1982 Jun 14	7104327
Ganglioside biosynthesis in rat liver: alteration of sialyltransferase activities by nucleotides.	Eppler CM Morré DJ Keenan TW	Biochim Biophys Acta	1980 Aug 11	7407217
Optimal conditions for the assay of fibroblast neuraminidase with different natural substrates.	Caimi L Lombardo A Preti A Wiesmann U Tettamanti G	Biochim Biophys Acta	1979 Nov 9	40610
Tissue distribution of EDTA encapsulated within liposomes containing glycolipids or brain phospholipids.	Jonah MM Cerny EA Rahman YE	Biochim Biophys Acta	1978 Jul 3	96869

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

All Resources

Other Information

Tools

Search Tools

Guidelines

Summary

External Links

KEGG BRITE Database

GlycoEpitope

Sequence Descriptors

International Collaboration

Acknowledgements