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Glycan Structure Repository
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Repository for lectin-assisted multimodality data
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G49108TO
Summary
- GlyTouCan ID
-
G49108TO
- IUPAC Condensed
- GlcNAc(b1-
3D Structures
- GlycoNAVI
- G49108TO
- GLYCAM
- DGlcpNAcb1-OH
G14843DJ
G68544GH
Organisms
| Organisms | Evidence |
|---|---|
| Mus musculus (house mouse) | |
| Rattus norvegicus (Norway rat) | |
| Homo sapiens (human) | |
| Drosophila melanogaster (fruit fly) | |
| Streptococcus pneumoniae |
Taxonomic Hierarchy
GlycoGene Database (GGDB)
| Gene Symbol | Donor | Acceptor | Reducing terminal(Acceptor) | Product | Reducing terminal(Product) | Reference |
|---|---|---|---|---|---|---|
| B4GALT5 | (not applicable) |
G49108TO
|
[beta]-S-pNP |
G00055MO
|
[beta]-S-pNP | |
| B3GALT2 | UDP-Gal |
G49108TO
|
Lemieux |
G00056MO
|
Lemieux | |
| B4GALT2 | UDP-Gal |
G49108TO
|
Benzyl-[beta] |
G00055MO
|
Benzyl-[beta] | |
| B4GALT1 | UDP-Gal |
G49108TO
|
R |
G00055MO
|
R | |
| B3GALT5 | UDP-Gal |
G49108TO
|
R |
G00056MO
|
R |
| Gene Symbol | Donor | Acceptor | Reducing terminal(Acceptor) | Product | Reducing terminal(Product) | Reference |
|---|---|---|---|---|---|---|
| B4GALT5 | (not applicable) |
G49108TO
|
[beta]-S-pNP |
G00055MO
|
[beta]-S-pNP | |
| B4GALT3 | UDP-Gal |
G49108TO
|
Benzyl-[beta] |
G00055MO
|
Benzyl-[beta] | |
| B4GALT4 | UDP-Gal |
G49108TO
|
[beta]-1-Benzl |
G00055MO
|
[beta]-1-Benzl | |
| B3GALT2 | UDP-Gal |
G49108TO
|
Lemieux |
G00056MO
|
Lemieux | |
| B4GALT4 | UDP-Gal |
G49108TO
|
[beta]-1-4-methyl-umbelliferyl |
G00055MO
|
[beta]-1-4-methyl-umbelliferyl |
Core Protein
| UniProt ID | Protein Name | Reference | Source |
|---|---|---|---|
| Q9Y6Y8 | SEC23-interacting protein | ||
| Q9Z0F7 | Gamma-synuclein | ||
| Q9Z0G2 | SRSF protein kinase 3 | ||
| Q9Z0H8 | CAP-Gly domain-containing linker protein 2 | ||
| Q9Z0I7 | Schlafen family member 1 | ||
| Q9Z0K8 | Pantetheinase | ||
| Q9Z0M1 | Kallikrein-4 | ||
| Q9Z0M3 | Cadherin-20 | ||
| Q9Z0N1 | Eukaryotic translation initiation factor 2 subunit 3, X-linked | ||
| Q9Z0P4 | Paralemmin-1 |
GlycoEpitope
- Epitope ID
- EP0004
Pathway
| Pathway Name | Organism |
|---|---|
| Ficolins bind to repetitive carbohydrate structures on the target cell surface | Rattus norvegicus |
| Initial triggering of complement | Sus scrofa |
| Initial triggering of complement | Xenopus tropicalis |
| Initial triggering of complement | Gallus gallus |
| Initial triggering of complement | Homo sapiens |
| Initial triggering of complement | Bos taurus |
| Initial triggering of complement | Mus musculus |
| Initial triggering of complement | Rattus norvegicus |
| Initial triggering of complement | Canis familiaris |
| Lectin pathway of complement activation | Sus scrofa |
Sequence Descriptors
- GlycoCT
-
RES 1b:b-dglc-HEX-1:5 2s:n-acetyl LIN 1:1d(2+1)2n
- WURCS
- WURCS=2.0/1,1,0/[a2122h-1b_1-5_2*NCC/3=O]/1/
Literature
| PubMed ID | Title | First Author | Publication Date | Source |
|---|---|---|---|---|
| 36191180 | Structural and inhibitor sensitivity analysis of influenza B–like viral neuraminidases derived from Asiatic toad and spiny eel | Li L | 2022 Oct 03 |
|
| 36190502 | N-acetylglucosamine-bearing polymers mimicking O-GlcNAc-modified proteins elicit anti-fibrotic activities in myofibroblasts and activated stellate cells | Ise H | 2022 Oct 03 |
|
| 35987426 | Differential expression of glycans in the urothelial layers of horse urinary bladder | Desantis S | 2022 Oct |
|
| 36116553 | Structural and functional studies of legumain–mycocypin complexes revealed a competitive, exosite-regulated mode of interaction | Elamin T | 2022 Oct |
|
| 35940108 | N-acetylglucosamine kinase, Hxk1 is a multifaceted metabolic enzyme in model pathogenic yeast Candida albicans | Rao KH | 2022 Oct |
|
| 36253002 | Localized ablative immunotherapy drives de novo CD8+T-cell responses to poorly immunogenic tumors | Hoover AR | 2022 Oct |
|
| 36049664 | The role and potential mechanism of O-Glycosylation in gastrointestinal tumors | Zhou F | 2022 Oct |
|
| 36031106 | An overview of tools to decipher O-GlcNAcylation from historical approaches to new insights | Dupas T | 2022 Oct |
|
| 36165873 | Fatty acid binding protein is required for chitin biosynthesis in the wing of Drosophila melanogaster | Chen J | 2022 Oct |
|
| 36031420 | Hypoxia-triggered O-GlcNAcylation in the brain drives the glutamate-glutamine cycle and reduces sensitivity to sevoflurane in mice | He Q | 2022 Nov |
|
PubAnnotation
| Title | Authors | Source | Publication Date | PubMed ID |
|---|---|---|---|---|
| Phosphorylation activates master growth regulator DELLA by promoting histone H2A binding at chromatin in Arabidopsis. |
|
Nat Commun | 2024 Sep 3 | 39227587 |
| A protein O-GlcNAc glycosyltransferase regulates the antioxidative response in Yersinia pestis. |
|
Nat Commun | 2024 Aug 16 | 39152136 |
| Polη O-GlcNAcylation governs genome integrity during translesion DNA synthesis. |
|
Nat Commun | 2017 Dec 5 | 29208956 |
| Epithelial Mesenchymal Transition Induces Aberrant Glycosylation through Hexosamine Biosynthetic Pathway Activation. |
|
J Biol Chem | 2016 Jun 17 | 27129262 |
| The making of a sweet modification: structure and function of O-GlcNAc transferase. |
|
J Biol Chem | 2014 Dec 12 | 25336649 |
