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Glycan Structure Repository
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Repository for lectin-assisted multimodality data
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G49108TO
Summary
- GlyTouCan ID
-
G49108TO
- IUPAC Condensed
- GlcNAc(b1-
3D Structures
- GLYCAM
- DGlcpNAcb1-OH
G14843DJ
G68544GH
Organisms
| Organisms | Evidence |
|---|---|
| Mus musculus (house mouse) | |
| Rattus norvegicus (Norway rat) | |
| Homo sapiens (human) | |
| Drosophila melanogaster (fruit fly) | |
| Streptococcus pneumoniae |
Taxonomic Hierarchy
GlycoGene Database (GGDB)
| Gene Symbol | Donor | Acceptor | Reducing terminal(Acceptor) | Product | Reducing terminal(Product) | Reference |
|---|---|---|---|---|---|---|
| B4GALT5 | (not applicable) |
G49108TO
|
[beta]-S-pNP |
G00055MO
|
[beta]-S-pNP | |
| B3GALT2 | UDP-Gal |
G49108TO
|
Lemieux |
G00056MO
|
Lemieux | |
| B4GALT2 | UDP-Gal |
G49108TO
|
Benzyl-[beta] |
G00055MO
|
Benzyl-[beta] | |
| B4GALT1 | UDP-Gal |
G49108TO
|
R |
G00055MO
|
R | |
| B3GALT5 | UDP-Gal |
G49108TO
|
R |
G00056MO
|
R |
| Gene Symbol | Donor | Acceptor | Reducing terminal(Acceptor) | Product | Reducing terminal(Product) | Reference |
|---|---|---|---|---|---|---|
| B4GALT5 | (not applicable) |
G49108TO
|
[beta]-S-pNP |
G00055MO
|
[beta]-S-pNP | |
| B4GALT3 | UDP-Gal |
G49108TO
|
Benzyl-[beta] |
G00055MO
|
Benzyl-[beta] | |
| B4GALT4 | UDP-Gal |
G49108TO
|
[beta]-1-Benzl |
G00055MO
|
[beta]-1-Benzl | |
| B3GALT2 | UDP-Gal |
G49108TO
|
Lemieux |
G00056MO
|
Lemieux | |
| B4GALT4 | UDP-Gal |
G49108TO
|
[beta]-1-4-methyl-umbelliferyl |
G00055MO
|
[beta]-1-4-methyl-umbelliferyl |
Core Protein
| UniProt ID | Protein Name | Reference | Source |
|---|---|---|---|
| P09951 | Synapsin-1 | ||
| P09960 | Leukotriene A-4 hydrolase | ||
| P0C090 | Roquin-2 | ||
| P0C0L4 | Complement C4-A | ||
| P0C0L5 | Complement C4-B | ||
| P0C0S5 | Histone H2A.Z | ||
| P0C0S8 | Histone H2A type 1 | ||
| P0C629 | Olfactory receptor 10J4 | ||
| P0C671 | Protein BNIP5 | ||
| P0C673 | Immunoglobulin superfamily member 11 |
GlycoEpitope
- Epitope ID
- EP0004
Pathway
| Pathway Name | Organism |
|---|---|
| Lectin pathway of complement activation | Mus musculus |
| Lectin pathway of complement activation | Bos taurus |
| Lectin pathway of complement activation | Rattus norvegicus |
| Lectin pathway of complement activation | Xenopus tropicalis |
| Lectin pathway of complement activation | Gallus gallus |
| Lectin pathway of complement activation | Homo sapiens |
| Lectin pathway of complement activation | Canis familiaris |
Sequence Descriptors
- GlycoCT
-
RES 1b:b-dglc-HEX-1:5 2s:n-acetyl LIN 1:1d(2+1)2n
- WURCS
- WURCS=2.0/1,1,0/[a2122h-1b_1-5_2*NCC/3=O]/1/
Literature
| PubMed ID | Title | First Author | Publication Date | Source |
|---|---|---|---|---|
| 38159850 | Tools for investigating O-GlcNAc in signaling and other fundamental biological pathways | Nelson ZM | 2024 Feb |
|
| 38277719 | Microbial production of N-acetyl-D-glucosamine (GlcNAc) for versatile applications: Biotechnological strategies for green process development | Das S | 2024 Feb |
|
| 38182007 | A viral insulin-like peptide inhibits IGF-1 receptor phosphorylation and regulates IGF1R gene expression | Chrudinová M | 2024 Feb |
|
| 39053763 | Dihydroartemisinin promotes tau O-GlcNAcylation and improves cognitive function in hTau transgenic mice | Xia L | 2024 Dec 20 |
|
| 39383863 | A potent pan-sarbecovirus neutralizing antibody resilient to epitope diversification | Rosen LE | 2024 Dec 12 |
|
| 39488210 | Isolation and escape mapping of broadly neutralizing antibodies against emerging delta-coronaviruses | Rexhepaj M | 2024 Dec 10 |
|
| 39516052 | Increased O-GlcNAcylation connects metabolic to transcriptional reprogramming during pathophysiological cell activation | Very N | 2024 Dec |
|
| 39481848 | Multi-omics after O-GlcNAc alteration identified cellular processes promoting aneuploidy after loss of O-GlcNAc transferase | Boyd SS | 2024 Dec |
|
| 39224128 | Exploring the therapeutic potential of prolinamides as multi-targeted agents for Alzheimer’s disease treatment: molecular docking and molecular dynamic simulation studies | Olalekan SO | 2024 Aug 31 |
|
| 39213338 | Germline-targeting HIV vaccination induces neutralizing antibodies to the CD4 binding site | Caniels TG | 2024 Aug 30 |
|
PubAnnotation
| Title | Authors | Source | Publication Date | PubMed ID |
|---|---|---|---|---|
| Dynamic glycosylation of the transcription factor CREB: a potential role in gene regulation. |
|
J Am Chem Soc | 2003 Jun 4 | 12769553 |
| Effect of okadaic acid on O-linked N-acetylglucosamine levels in a neuroblastoma cell line. |
|
Biochim Biophys Acta | 1999 Oct 18 | 10572927 |
| Regulation of a cytosolic and nuclear O-GlcNAc transferase. Role of the tetratricopeptide repeats. |
|
J Biol Chem | 1999 Nov 5 | 10542233 |
| An N-terminal region of Sp1 targets its proteasome-dependent degradation in vitro. |
|
J Biol Chem | 1999 May 21 | 10329728 |
| Vertebrate lens alpha-crystallins are modified by O-linked N-acetylglucosamine. |
|
J Biol Chem | 1992 Jan 5 | 1730617 |
