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Repository for lectin-assisted multimodality data
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G49108TO
Summary
- GlyTouCan ID
-
G49108TO
- IUPAC Condensed
- GlcNAc(b1-
3D Structures
- GlycoNAVI
- G49108TO
- GLYCAM
- DGlcpNAcb1-OH
G14843DJ
G68544GH
Organisms
| Organisms | Evidence |
|---|---|
| Mus musculus (house mouse) | |
| Rattus norvegicus (Norway rat) | |
| Homo sapiens (human) | |
| Drosophila melanogaster (fruit fly) | |
| Streptococcus pneumoniae |
Taxonomic Hierarchy
GlycoGene Database (GGDB)
| Gene Symbol | Donor | Acceptor | Reducing terminal(Acceptor) | Product | Reducing terminal(Product) | Reference |
|---|---|---|---|---|---|---|
| B4GALT5 | (not applicable) |
G49108TO
|
[beta]-S-pNP |
G00055MO
|
[beta]-S-pNP | |
| B3GALT2 | UDP-Gal |
G49108TO
|
Lemieux |
G00056MO
|
Lemieux | |
| B4GALT2 | UDP-Gal |
G49108TO
|
Benzyl-[beta] |
G00055MO
|
Benzyl-[beta] | |
| B4GALT1 | UDP-Gal |
G49108TO
|
R |
G00055MO
|
R | |
| B3GALT5 | UDP-Gal |
G49108TO
|
R |
G00056MO
|
R |
| Gene Symbol | Donor | Acceptor | Reducing terminal(Acceptor) | Product | Reducing terminal(Product) | Reference |
|---|---|---|---|---|---|---|
| B4GALT5 | (not applicable) |
G49108TO
|
[beta]-S-pNP |
G00055MO
|
[beta]-S-pNP | |
| B4GALT3 | UDP-Gal |
G49108TO
|
Benzyl-[beta] |
G00055MO
|
Benzyl-[beta] | |
| B4GALT4 | UDP-Gal |
G49108TO
|
[beta]-1-Benzl |
G00055MO
|
[beta]-1-Benzl | |
| B3GALT2 | UDP-Gal |
G49108TO
|
Lemieux |
G00056MO
|
Lemieux | |
| B4GALT4 | UDP-Gal |
G49108TO
|
[beta]-1-4-methyl-umbelliferyl |
G00055MO
|
[beta]-1-4-methyl-umbelliferyl |
Core Protein
| UniProt ID | Protein Name | Reference | Source |
|---|---|---|---|
| Q9Y6H5 | Synphilin-1 | ||
| Q9Y6I3 | Epsin-1 | ||
| Q9Y6J0 | Calcineurin-binding protein cabin-1 | ||
| Q9Y6K5 | 2'-5'-oligoadenylate synthase 3 | ||
| Q9Y6M7 | Sodium bicarbonate cotransporter 3 | ||
| Q9Y6N1 | Cytochrome c oxidase assembly protein COX11, mitochondrial | ||
| Q9Y6N7 | Roundabout homolog 1 | ||
| Q9Y6Q2 | Stonin-1 | ||
| Q9Y6Q5 | AP-1 complex subunit mu-2 | ||
| Q9Y6Q9 | Nuclear receptor coactivator 3 |
GlycoEpitope
- Epitope ID
- EP0004
Pathway
| Pathway Name | Organism |
|---|---|
| Lectin pathway of complement activation | Mus musculus |
| Lectin pathway of complement activation | Bos taurus |
| Lectin pathway of complement activation | Rattus norvegicus |
| Lectin pathway of complement activation | Xenopus tropicalis |
| Lectin pathway of complement activation | Gallus gallus |
| Lectin pathway of complement activation | Homo sapiens |
| Lectin pathway of complement activation | Canis familiaris |
Sequence Descriptors
- GlycoCT
-
RES 1b:b-dglc-HEX-1:5 2s:n-acetyl LIN 1:1d(2+1)2n
- WURCS
- WURCS=2.0/1,1,0/[a2122h-1b_1-5_2*NCC/3=O]/1/
Literature
| PubMed ID | Title | First Author | Publication Date | Source |
|---|---|---|---|---|
| 38016609 | Revealing the conformational dynamics of UDP-GlcNAc recognition by O-GlcNAc transferase via Markov state model | Tian J | 2024 Jan |
|
| 38142486 | Characterization of the bispecific VHH antibody gefurulimab (ALXN1720) targeting complement component 5, and designed for low volume subcutaneous administration | Jindal S | 2024 Jan |
|
| 38043191 | Role of O-GlcNAcylation in cancer biology | Li Y | 2024 Jan |
|
| 38474090 | Influence of N-Acetylglucosamine and Melatonin Interaction in Modeling the Photosynthetic Component and Metabolomics of Cucumber under Salinity Stress | Kang SM | 2024 Feb 29 |
|
| 38474544 | Efficient Escorting Strategy for Aggregation-Prone Notch EGF Repeats with Sparcl1 | Kondo Y | 2024 Feb 27 |
|
| 38401165 | Chemo-enzymatic synthesis of tetrasaccharide linker peptides to study the divergent step in glycosaminoglycan biosynthesis | Bourgeais M | 2024 Feb 24 |
|
| 38396292 | O-GlcNAcylation of E3 ubiquitin ligase SKP2 promotes hepatocellular carcinoma proliferation | Feng Z | 2024 Feb 23 |
|
| 38559739 | Mechanistic Insights into Dibasic Iminosugars as pH-Selective Pharmacological Chaperones to Stabilize Human α-Galactosidase | Li HY | 2024 Feb 23 |
|
| 38389178 | OGT-induced O-GlcNAcylation of NEK7 protein aggravates osteoarthritis progression by enhancing NEK7/NLRP3 axis | He C | 2024 Feb 22 |
|
| 38380729 | VWD domain stabilization by autocatalytic Asp‐Pro cleavage | Yeshaya N | 2024 Feb 21 |
|
PubAnnotation
| Title | Authors | Source | Publication Date | PubMed ID |
|---|---|---|---|---|
| Phosphorylation activates master growth regulator DELLA by promoting histone H2A binding at chromatin in Arabidopsis. |
|
Nat Commun | 2024 Sep 3 | 39227587 |
| A protein O-GlcNAc glycosyltransferase regulates the antioxidative response in Yersinia pestis. |
|
Nat Commun | 2024 Aug 16 | 39152136 |
| Polη O-GlcNAcylation governs genome integrity during translesion DNA synthesis. |
|
Nat Commun | 2017 Dec 5 | 29208956 |
| Epithelial Mesenchymal Transition Induces Aberrant Glycosylation through Hexosamine Biosynthetic Pathway Activation. |
|
J Biol Chem | 2016 Jun 17 | 27129262 |
| The making of a sweet modification: structure and function of O-GlcNAc transferase. |
|
J Biol Chem | 2014 Dec 12 | 25336649 |
