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Repository for lectin-assisted multimodality data
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G49108TO
Summary
- GlyTouCan ID
-
G49108TO
- IUPAC Condensed
- GlcNAc(b1-
3D Structures
- GlycoNAVI
- G49108TO
- GLYCAM
- DGlcpNAcb1-OH
G14843DJ
G68544GH
Organisms
| Organisms | Evidence |
|---|---|
| Mus musculus (house mouse) | |
| Rattus norvegicus (Norway rat) | |
| Homo sapiens (human) | |
| Drosophila melanogaster (fruit fly) | |
| Streptococcus pneumoniae |
Taxonomic Hierarchy
GlycoGene Database (GGDB)
| Gene Symbol | Donor | Acceptor | Reducing terminal(Acceptor) | Product | Reducing terminal(Product) | Reference |
|---|---|---|---|---|---|---|
| B4GALT5 | (not applicable) |
G49108TO
|
[beta]-S-pNP |
G00055MO
|
[beta]-S-pNP | |
| B3GALT2 | UDP-Gal |
G49108TO
|
Lemieux |
G00056MO
|
Lemieux | |
| B4GALT2 | UDP-Gal |
G49108TO
|
Benzyl-[beta] |
G00055MO
|
Benzyl-[beta] | |
| B4GALT1 | UDP-Gal |
G49108TO
|
R |
G00055MO
|
R | |
| B3GALT5 | UDP-Gal |
G49108TO
|
R |
G00056MO
|
R |
| Gene Symbol | Donor | Acceptor | Reducing terminal(Acceptor) | Product | Reducing terminal(Product) | Reference |
|---|---|---|---|---|---|---|
| B4GALT5 | (not applicable) |
G49108TO
|
[beta]-S-pNP |
G00055MO
|
[beta]-S-pNP | |
| B4GALT3 | UDP-Gal |
G49108TO
|
Benzyl-[beta] |
G00055MO
|
Benzyl-[beta] | |
| B4GALT4 | UDP-Gal |
G49108TO
|
[beta]-1-Benzl |
G00055MO
|
[beta]-1-Benzl | |
| B3GALT2 | UDP-Gal |
G49108TO
|
Lemieux |
G00056MO
|
Lemieux | |
| B4GALT4 | UDP-Gal |
G49108TO
|
[beta]-1-4-methyl-umbelliferyl |
G00055MO
|
[beta]-1-4-methyl-umbelliferyl |
Core Protein
| UniProt ID | Protein Name | Reference | Source |
|---|---|---|---|
| A2AHG0 | Leucine zipper putative tumor suppressor 3 | ||
| A2AHJ4 | Bromodomain and WD repeat-containing protein 3 | ||
| A2AIR2 | E3 ubiquitin protein ligase (Fragment) | ||
| A2AIV2 | Protein virilizer homolog | ||
| A2AJ76 | Hemicentin-2 | ||
| A2AJA9 | Apical junction component 1 homolog | ||
| A2AJI0 | MAP7 domain-containing protein 1 | ||
| A2AKB9 | DDB1- and CUL4-associated factor 10 | ||
| A2AKX3 | Probable helicase senataxin | ||
| A2ALS5 | Rap1 GTPase-activating protein 1 |
GlycoEpitope
- Epitope ID
- EP0004
Pathway
| Pathway Name | Organism |
|---|---|
| Antimicrobial peptides | Rattus norvegicus |
| E.coli O10 | Escherichia coli |
| E.coli O103 | Escherichia coli |
| E.coli O105 | Escherichia coli |
| E.coli O109 | Escherichia coli |
| E.coli O110 | Escherichia coli |
| E.coli O111 | Escherichia coli |
| E.coli O112ab | Escherichia coli |
| E.coli O113 | Escherichia coli |
| E.coli O115 | Escherichia coli |
Sequence Descriptors
- GlycoCT
-
RES 1b:b-dglc-HEX-1:5 2s:n-acetyl LIN 1:1d(2+1)2n
- WURCS
- WURCS=2.0/1,1,0/[a2122h-1b_1-5_2*NCC/3=O]/1/
Literature
| PubMed ID | Title | First Author | Publication Date | Source |
|---|---|---|---|---|
| 37428845 | 3D structures of the Plasmodium vivax subtilisin-like drug target SUB1 reveal conformational changes to accommodate a substrate-derived α-ketoamide inhibitor | Martinez M | 2023 Jul 10 |
|
| 37279852 | O-GlcNAcylation in cancer development and immunotherapy | He XF | 2023 Jul 10 |
|
| 37422472 | The structural pathology for hypophosphatasia caused by malfunctional tissue non-specific alkaline phosphatase | Yu Y | 2023 Jul 08 |
|
| 37446392 | Identification of Regulatory Molecular “Hot Spots” for LH/PLOD Collagen Glycosyltransferase Activity | Mattoteia D | 2023 Jul 07 |
|
| 37390815 | Glucose-induced CRL4COP1-p53 axis amplifies glycometabolism to drive tumorigenesis | Su Y | 2023 Jul 06 |
|
| 37409796 | Efficient Production of N-Acetylneuraminic Acid in Escherichia coli Based on the UDP-N-Acetylglucosamine Biosynthetic Pathway | Zhao M | 2023 Jul 06 |
|
| 37357620 | Crystal structures of Na+,K+‐ATPase reveal the mechanism that converts the K+‐bound form to Na+‐bound form and opens and closes the cytoplasmic gate | Kanai R | 2023 Jul 06 |
|
| 37407593 | Structure of engineered hepatitis C virus E1E2 ectodomain in complex with neutralizing antibodies | Metcalf MC | 2023 Jul 05 |
|
| 37395731 | Author response: Sterol derivative binding to the orthosteric site causes conformational changes in an invertebrate Cys-loop receptor | De Gieter S | 2023 Jul 03 |
|
| 37400538 | Discovery of VH domains that allosterically inhibit ENPP1 | Solomon PE | 2023 Jul 03 |
|
PubAnnotation
| Title | Authors | Source | Publication Date | PubMed ID |
|---|---|---|---|---|
| Phosphorylation activates master growth regulator DELLA by promoting histone H2A binding at chromatin in Arabidopsis. |
|
Nat Commun | 2024 Sep 3 | 39227587 |
| A protein O-GlcNAc glycosyltransferase regulates the antioxidative response in Yersinia pestis. |
|
Nat Commun | 2024 Aug 16 | 39152136 |
| Polη O-GlcNAcylation governs genome integrity during translesion DNA synthesis. |
|
Nat Commun | 2017 Dec 5 | 29208956 |
| Epithelial Mesenchymal Transition Induces Aberrant Glycosylation through Hexosamine Biosynthetic Pathway Activation. |
|
J Biol Chem | 2016 Jun 17 | 27129262 |
| The making of a sweet modification: structure and function of O-GlcNAc transferase. |
|
J Biol Chem | 2014 Dec 12 | 25336649 |
