G49108TO
| Organisms | Evidence | 
|---|---|
| Mus musculus (house mouse) | |
| Rattus norvegicus (Norway rat) | |
| Homo sapiens (human) | |
| Drosophila melanogaster (fruit fly) | |
| Streptococcus pneumoniae | 
| Gene Symbol | Donor | Acceptor | Reducing terminal(Acceptor) | Product | Reducing terminal(Product) | Reference | 
|---|---|---|---|---|---|---|
| B4GALT5 | (not applicable) | 
                          
                             | 
                    [beta]-S-pNP | 
                          
                             | 
                    [beta]-S-pNP | |
| B3GALT2 | UDP-Gal | 
                          
                             | 
                    Lemieux | 
                          
                             | 
                    Lemieux | |
| B4GALT2 | UDP-Gal | 
                          
                             | 
                    Benzyl-[beta] | 
                          
                             | 
                    Benzyl-[beta] | |
| B4GALT1 | UDP-Gal | 
                          
                             | 
                    R | 
                          
                             | 
                    R | |
| B3GALT5 | UDP-Gal | 
                          
                             | 
                    R | 
                          
                             | 
                    R | 
| Gene Symbol | Donor | Acceptor | Reducing terminal(Acceptor) | Product | Reducing terminal(Product) | Reference | 
|---|---|---|---|---|---|---|
| B4GALT5 | (not applicable) | 
                          
                             | 
                    [beta]-S-pNP | 
                          
                             | 
                    [beta]-S-pNP | |
| B4GALT3 | UDP-Gal | 
                          
                             | 
                    Benzyl-[beta] | 
                          
                             | 
                    Benzyl-[beta] | |
| B4GALT4 | UDP-Gal | 
                          
                             | 
                    [beta]-1-Benzl | 
                          
                             | 
                    [beta]-1-Benzl | |
| B3GALT2 | UDP-Gal | 
                          
                             | 
                    Lemieux | 
                          
                             | 
                    Lemieux | |
| B4GALT4 | UDP-Gal | 
                          
                             | 
                    [beta]-1-4-methyl-umbelliferyl | 
                          
                             | 
                    [beta]-1-4-methyl-umbelliferyl | 
| UniProt ID | Protein Name | Reference | Source | 
|---|---|---|---|
| O75949 | NALCN channel auxiliary factor 2 | ||
| O75952 | Calcium-binding tyrosine phosphorylation-regulated protein | ||
| O75956 | Cyclin-dependent kinase 2-associated protein 2 | ||
| O75962 | Triple functional domain protein | ||
| O75973 | C1q-related factor | ||
| O75976 | Carboxypeptidase D | ||
| O76021 | Ribosomal L1 domain-containing protein 1 | ||
| O76027 | Annexin A9 | ||
| O76031 | ATP-dependent clpX-like chaperone, mitochondrial | ||
| O76038 | Secretagogin | 
| Pathway Name | Organism | 
|---|---|
| E.coli O28ab | Escherichia coli | 
| E.coli O28ac | Escherichia coli | 
| E.coli O29 | Escherichia coli | 
| E.coli O3 | Escherichia coli | 
| E.coli O30 | Escherichia coli | 
| E.coli O32 | Escherichia coli | 
| E.coli O35 | Escherichia coli | 
| E.coli O36 | Escherichia coli | 
| E.coli O37 | Escherichia coli | 
| E.coli O38 | Escherichia coli | 
RES 1b:b-dglc-HEX-1:5 2s:n-acetyl LIN 1:1d(2+1)2n
| PubMed ID | Title | First Author | Publication Date | Source | 
|---|---|---|---|---|
| 37806254 | SIRT1 Asn346 sugar chain promoting collagen deacetylation protective effect on osteoblasts under stress | Cai M | 2023 Nov 19 | 
                  
  | 
          
| 37804113 | Cross-species recognition of bat coronavirus RsYN04 and cross-reaction of SARS-CoV-2 antibodies against the virus | Zhao R | 2023 Nov 18 | 
                  
  | 
          
| 37980352 | Activation and substrate specificity of the human P4-ATPase ATP8B1 | Dieudonné T | 2023 Nov 18 | 
                  
  | 
          
| 38026167 | O-GlcNAcylation regulates OTX2's proteostasis | Wulff-Fuentes E | 2023 Nov 17 | 
                  
  | 
          
| 37962578 | O-GlcNAc modification of GSDMD attenuates LPS-induced endothelial cells pyroptosis | Yu F | 2023 Nov 14 | 
                  
  | 
          
| 37963851 | O-GlcNAcylation Regulates Centrosome Behavior and Cell Polarity to Reduce Pulmonary Fibrosis and Maintain the Epithelial Phenotype | Yu F | 2023 Nov 14 | 
                  
  | 
          
| 37963940 | SETD5 regulates the OGT-catalyzed O-GlcNAcylation of RNA polymerase II, which is involved in the stemness of colorectal cancer cells | Cho HI | 2023 Nov 14 | 
                  
  | 
          
| 37890481 | SMPDL3A is a cGAMP-degrading enzyme induced by LXR-mediated lipid metabolism to restrict cGAS-STING DNA sensing | Hou Y | 2023 Nov 14 | 
                  
  | 
          
| 37991488 | Author response: Lys417 acts as a molecular switch that regulates the conformation of SARS-CoV-2 spike protein | Geng Q | 2023 Nov 09 | 
                  
  | 
          
| 37934975 | Novel Calcium-Binding Motif Stabilizes and Increases the Activity of Aspergillus fumigatus Ecto-NADase | Ferrario E | 2023 Nov 07 | 
                  
  | 
          
| Title | Authors | Source | Publication Date | PubMed ID | 
|---|---|---|---|---|
| Dynamic glycosylation of the transcription factor CREB: a potential role in gene regulation. | 
                  
  | 
                    J Am Chem Soc | 2003 Jun 4 | 12769553 | 
| Effect of okadaic acid on O-linked N-acetylglucosamine levels in a neuroblastoma cell line. | 
                  
  | 
                    Biochim Biophys Acta | 1999 Oct 18 | 10572927 | 
| Regulation of a cytosolic and nuclear O-GlcNAc transferase. Role of the tetratricopeptide repeats. | 
                  
  | 
                    J Biol Chem | 1999 Nov 5 | 10542233 | 
| An N-terminal region of Sp1 targets its proteasome-dependent degradation in vitro. | 
                  
  | 
                    J Biol Chem | 1999 May 21 | 10329728 | 
| Vertebrate lens alpha-crystallins are modified by O-linked N-acetylglucosamine. | 
                  
  | 
                    J Biol Chem | 1992 Jan 5 | 1730617 | 
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Supported by JST NBDC Grant Number JPMJND2204
Partly supported by NIH Common Fund Grant #1U01GM125267-01
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