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G98544DH

Summary

GlyTouCan ID: G98544DH
IUPAC Condensed: Neu5Ac(a2-8)Neu5Ac(a2-3)Gal(b1-4)Glc(b1-
Motifs: 9-O-Acetyl GD3 GD3
Subsumption Level: Fully-defined saccharide
Monoisotopic Mass: 924.31

External Links

GlyGen

G98544DH

ChEBI

59210

PubChem Compound

45266862

PubChem Substance

252288444

GlycoShape

Displaying 1 entry
Archetype	α	β
G10158SF	G58409WK	G98544DH

3D Structures

GlycoShape: G98544DH
GLYCAM: Neup5Aca2-8Neup5Aca2-3DGalpb1-4DGlcpb1-OH

Organisms

Displaying entries **1 - 5** of 24 in total

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Organisms	Evidence
Macaca mulatta (Rhesus monkey)	GlyTouCan(glycome-db)
Chinchilla	GlyTouCan(glycome-db)
Macaca fuscata (Japanese macaque)	GlyTouCan(glycome-db)
Galliformes (landfowls)	GlyTouCan(glycome-db)
Mus musculus (house mouse)	GlyTouCan(glycome-db)

Taxonomic Hierarchy

root

cellular organisms [inference]

Eukaryota (eucaryotes) [inference]

Opisthokonta [inference]

Metazoa (metazoans) [inference]

Eumetazoa [inference]

Bilateria [inference]

Deuterostomia [inference]

Chordata (chordates) [inference]

Craniata [inference]

Vertebrata (vertebrates) [inference]

Gnathostomata (jawed vertebrates) [inference]

Chondrichthyes (cartilaginous fishes) [inference]

Elasmobranchii (elasmobranchs) [inference]

Batoidea (rays) [inference]

Rajiformes (skates) [inference]

Rajidae (hardnose skates) [inference]

Leucoraja [inference]

Leucoraja erinacea (little skate)

Torpediniformes [inference]

Torpedinidae (electric rays) [inference]

Torpedo [inference]

Torpedo marmorata (marbled electric ray)

Narcinidae (numbfishes) [inference]

Discopyge [inference]

Discopyge tschudii (apron ray)

Teleostomi [inference]

Euteleostomi (bony vertebrates) [inference]

Sarcopterygii [inference]

Dipnotetrapodomorpha [inference]

Tetrapoda (tetrapods) [inference]

Amniota (amniotes) [inference]

Mammalia (mammals) [inference]

Theria [inference]

Eutheria (placentals) [inference]

Boreoeutheria [inference]

Laurasiatheria [inference]

Artiodactyla (even-toed ungulates & whales) [inference]

Ruminantia [inference]

Pecora [inference]

Bovidae [inference]

Bovinae [inference]

Bos (cattle) [inference]

Bos taurus (domestic cattle)

Suina [inference]

Suidae (pigs) [inference]

Sus [inference]

Sus scrofa (pig)

Whippomorpha [inference]

Cetacea (whales) [inference]

Mysticeti (baleen whales) [inference]

Balaenopteridae (rorquals) [inference]

Balaenoptera [inference]

Balaenoptera edeni (pygmy Bryde's whale)

Carnivora (carnivores) [inference]

Caniformia [inference]

Canidae (dog, coyote, wolf, fox) [inference]

Canis [inference]

Canis lupus (gray wolf) [inference]

Canis lupus familiaris (dog)

Feliformia [inference]

Felidae (cat family) [inference]

Felinae [inference]

Felis [inference]

Felis catus (domestic cat)

Euarchontoglires [inference]

Glires (Rodents and rabbits) [inference]

Rodentia (rodent) [inference]

Hystricomorpha (guinea pigs and others) [inference]

Chinchillidae (chinchillas)

Chinchilla

Caviidae (cavies) [inference]

Cavia (guinea pigs) [inference]

Cavia porcellus (domestic guinea pig)

Myomorpha (mice and others) [inference]

Muroidea [inference]

Muridae [inference]

Murinae [inference]

Mus (mice) [inference]

Mus [inference]

Mus musculus (house mouse)

Rattus

Cricetidae [inference]

Cricetinae (hamsters)

Lagomorpha [inference]

Leporidae (rabbits and hares) [inference]

Oryctolagus [inference]

Oryctolagus cuniculus (rabbit)

Primates [inference]

Haplorrhini [inference]

Simiiformes [inference]

Catarrhini [inference]

Cercopithecoidea [inference]

Cercopithecidae (Old World monkeys) [inference]

Cercopithecinae [inference]

Macaca (macaques) [inference]

Papio (baboons) [inference]

Papio hamadryas (hamadryas baboon)

Hominoidea (apes) [inference]

Hominidae (great apes) [inference]

Homininae [inference]

Homo [inference]

Homo sapiens (human)

Sauropsida (sauropsids) [inference]

Sauria (diapsids) [inference]

Archelosauria [inference]

Archosauria [inference]

Dinosauria [inference]

Saurischia [inference]

Theropoda [inference]

Coelurosauria [inference]

Aves (birds) [inference]

Neognathae [inference]

Galloanserae [inference]

Galliformes (landfowls)

Phasianidae (turkeys) [inference]

Phasianinae [inference]

Gallus [inference]

Gallus gallus (chicken)

Amphibia (amphibians) [inference]

Batrachia [inference]

Anura (frogs and toads) [inference]

Pipoidea [inference]

Pipidae (tongueless frogs) [inference]

Xenopodinae [inference]

Xenopus

Actinopterygii (ray-finned fishes) [inference]

Actinopteri [inference]

Neopterygii [inference]

Teleostei (teleost fishes) [inference]

Osteoglossocephalai [inference]

Clupeocephala [inference]

Otomorpha [inference]

Ostariophysi [inference]

Otophysi [inference]

Cypriniphysae [inference]

Cypriniformes (carps and others) [inference]

Cyprinoidei [inference]

Cyprinidae [inference]

Cyprininae [inference]

Carassius [inference]

Carassius auratus (goldfish)

Bacteria (eubacteria) [inference]

Campylobacterota [inference]

Epsilonproteobacteria [inference]

Campylobacterales [inference]

Campylobacteraceae [inference]

Campylobacter [inference]

Campylobacter jejuni

GlycoGene Database (GGDB)

Displaying **all 4** entries
Gene Symbol	Donor	Acceptor	Reducing terminal(Acceptor)	Product	Reducing terminal(Product)	Reference
ST8SIA6	CMP-Neu5Ac	G91237TK	Cer	G98544DH	Cer	11980897
ST8SIA1	CMP-Neu5Ac	G91237TK	Cer	G98544DH	Cer	8195250
ST8SIA5	CMP-Neu5Ac	G98544DH	Cer	G93899SO	Cer	8910600
ST8SIA3	CMP-Neu5Ac	G91237TK	Cer	G98544DH	Cer	7782326

Displaying entries **1 - 5** of 7 in total

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Gene Symbol	Donor	Acceptor	Reducing terminal(Acceptor)	Product	Reducing terminal(Product)	Reference
ST8SIA6	CMP-Neu5Ac	G91237TK		G98544DH		11980897
ST8SIA6	CMP-Neu5Ac	G91237TK	Cer	G98544DH	Cer	11980897
ST8SIA1	CMP-Neu5Ac	G91237TK	Cer	G98544DH	Cer	8195250 8910600
ST8SIA5	CMP-Neu5Ac	G98544DH	Cer	G93899SO	Cer	8910600 9199191
ST8SIA3	CMP-Neu5Ac	G91237TK	Cer	G98544DH	Cer	7782326 8910600

Displaying **all 5** entries
Gene Symbol	Donor	Acceptor	Reducing terminal(Acceptor)	Reference
ST8SIA1	CMP-Neu5Ac	G98544DH	Cer	8910600
ST8SIA2	CMP-Neu5Ac	G98544DH	Cer	7782326
ST8SIA6	CMP-Neu5Ac	G98544DH	Cer	11980897 16120058
B4GALNT2	UDP-GalNAc	G98544DH	Cer	12678917
B3GALNT1	UDP-GalNAc	G98544DH	Cer	10993897

KEGG BRITE Database

KEGG ID

G00113

Enzyme

Reactions

Displaying **all 3** entries
KEGG Reaction	Enzyme	Acceptor	Product
R05940	2.4.3.8	G91237TK	G98544DH
R05946	2.4.1.92	G98544DH	G02657AK
R05947	2.4.3.8	G98544DH	G93899SO

GlycoEpitope

Epitope ID: EP0062
Epitope Name: N-Acetyl GD3

Sequence Descriptors

GlycoCT

RES
1b:b-dglc-HEX-1:5
2b:b-dgal-HEX-1:5
3b:a-dgro-dgal-NON-2:6|1:a|2:keto|3:d
4s:n-acetyl
5b:a-dgro-dgal-NON-2:6|1:a|2:keto|3:d
6s:n-acetyl
LIN
1:1o(4+1)2d
2:2o(3+2)3d
3:3d(5+1)4n
4:3o(8+2)5d
5:5d(5+1)6n

WURCS

WURCS=2.0/3,4,3/[a2122h-1b_1-5][a2112h-1b_1-5][Aad21122h-2a_2-6_5*NCC/3=O]/1-2-3-3/a4-b1_b3-c2_c8-d2

Literature

Displaying entries **31 - 40** of 48 in total

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PubMed ID	Title	First Author	Publication Date	Source
8410057	Reactivity of neuroborreliosis patients (Lyme disease) to cardiolipin and gangliosides	Moncó JCG	1993 Jul	PubChem
8262898	Characterization of Ganglioside Expression in Human Melanoma Cells: Immunological and Biochemical Analysis1	Kawashima I	1993 Aug	GlyGen GlycoEpitope
1601877	Expression cloning of beta 1,4 N-acetylgalactosaminyltransferase cDNAs that determine the expression of GM2 and GD2 gangliosides.	Nagata Y	1992 Jun 15	PubChem
1371229	Generation of one set of monoclonal antibodies specific for b-pathway ganglio-series gangliosides	Ozawa H	1992 Jan 24	GlyGen GlycoEpitope
1724444	Production of monoclonal antibodies specific for ganglioside GD3	Watarai S	1991 Dec	GlyGen GlycoEpitope
2111348	Northern hybridization analysis of VH gene expression in murine monoclonal antibodies directed to cancer-associated ganglioside antigens having various sialic acid linkages	Zenita K	1990 Jun 01	GlyGen GlycoEpitope
2908845	Two human monoclonal antibodies reacting with the major gangliosides of human melanomas and comparison with corresponding mouse monoclonal antibodies	Furukawa K	1989 Jan 01	GlyGen GlycoEpitope
2449128	Monoclonal antibody R24 distinguishes between different N-acetyl- and N-glycolylneuraminic acid derivatives of ganglioside GD3	Tai T	1988 Jan	GlyGen GlycoEpitope
3170507	Different fine binding specificities of monoclonal antibodies to disialosylganglioside GD2	Tai T	1988 Apr	GlyGen GlycoEpitope
3815333	Monoclonal antibody-defined correlations in melanoma between levels of GD2 and GD3 antigens and antibody-mediated cytotoxicity	Thurin J	1987 Mar 01	GlyGen GlycoEpitope

PubAnnotation

Displaying entries **6 - 10** of 10 in total

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Title	Authors	Source	Publication Date	PubMed ID
Trafficking of ganglioside GD3 to mitochondria by tumor necrosis factor-alpha.	García-Ruiz C Colell A Morales A Calvo M Enrich C Fernández-Checa JC	J Biol Chem	2002 Sep 27	12118012
Inhibition of integrin-linked kinase/protein kinase B/Akt signaling: mechanism for ganglioside-induced apoptosis.	Wang XQ Sun P Paller AS	J Biol Chem	2001 Nov 30	11577096
A synthetic approach to polysialogangliosides containing alpha-sialyl-(2-->8)-sialic acid: total synthesis of ganglioside GD3.	Ishida H Ohta Y Tsukada Y Kiso M Hasegawa A	Carbohydr Res	1993 Aug 17	8370046
Specific staining on thin-layer chromatograms of glycosphingolipids of neolacto series and gangliosides with a terminal N-acetylneuraminyl residue by different procedures with wheat germ agglutinin.	Higashi H Sugii T Kato S	Biochim Biophys Acta	1988 Nov 25	2461740
Proton NMR and fast-atom bombardment mass spectrometry analysis of the melanoma-associated ganglioside 9-O-acetyl-GD3.	Thurin J Herlyn M Hindsgaul O Strömberg N Karlsson KA Elder D Steplewski Z Koprowski H	J Biol Chem	1985 Nov 25	4055789

GlyTouCan

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UniCarb-DR

LM-GlycoRepo

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