G99053DY

Summary
GlyTouCan ID
G99053DY
IUPAC Condensed
Gal(b1-3)GalNAc(b1-3)Gal(a1-4)Gal(b1-4)Glc(b1-
Motifs
Gb5 SSEA-3
Subsumption Level
Fully-defined saccharide
Monoisotopic Mass
869.3
GlyGen
ChEBI
PubChem Compound
PubChem Substance
GlycoShape
Displaying 1 entry
Archetype α β
G90539LD
G70873KK
G99053DY
3D Structures
Organisms
GlycoGene Database (GGDB)
Displaying 1 entry
Gene Symbol Donor Acceptor Reducing terminal(Acceptor) Product Reducing terminal(Product) Reference
B3GALT5 UDP-Gal
G00061MO
Cer
G99053DY
Cer
Displaying 1 entry
Gene Symbol Donor Acceptor Reducing terminal(Acceptor) Product Reducing terminal(Product) Reference
B3GALT5 UDP-Gal
G00061MO
Cer
G99053DY
Cer
KEGG BRITE Database
KEGG ID
Enzyme
References
Reactions
Displaying all 2 entries
KEGG Reaction Enzyme Acceptor Product
R05967
R05968
GlycoEpitope
Epitope ID
EP0036
Epitope Name
Galactosylgloboside
Sequence Descriptors
GlycoCT
RES
1b:b-dglc-HEX-1:5
2b:b-dgal-HEX-1:5
3b:a-dgal-HEX-1:5
4b:b-dgal-HEX-1:5
5s:n-acetyl
6b:b-dgal-HEX-1:5
LIN
1:1o(4+1)2d
2:2o(4+1)3d
3:3o(3+1)4d
4:4d(2+1)5n
5:4o(3+1)6d
WURCS
WURCS=2.0/4,5,4/[a2122h-1b_1-5][a2112h-1b_1-5][a2112h-1a_1-5][a2112h-1b_1-5_2*NCC/3=O]/1-2-3-4-2/a4-b1_b4-c1_c3-d1_d3-e1
Literature
Displaying all 5 entries
PubMed ID Title First Author Publication Date Source
28076665 Carbohydrate–Lectin Interactions: An Unexpected Contribution to Affinity Navarra G 2017 Feb 07
  • PubChem
18773292 Complex N-glycans or core 1-derived O-glycans are not required for the expression of stage-specific antigens SSEA-1, SSEA-3, SSEA-4, or Le(Y) in the preimplantation mouse embryo Williams SA 2008 Sep 05
  • PubChem
10837462 The beta 1,3-galactosyltransferase beta 3GalT-V is a stage-specific embryonic antigen-3 (SSEA-3) synthase Zhou D 2000 Jul 28
  • PubChem
3364985 Monoclonal antibodies that bind to galactosylgloboside (SSEA-3 antigen) Marcus DM 1988 May 01
  • GlyGen
  • GlycoEpitope
2837767 Recognition of galactosylgloboside by monoclonal antibodies derived from patients with primary lung cancer Schrump DS 1988 Jun
  • GlyGen
  • GlycoEpitope
PubAnnotation
Displaying entries 1 - 5 of 10 in total
Title Authors Source Publication Date PubMed ID
Changes of glycoconjugate expression profiles during early development.
  • Handa K
  • Hakomori SI
Glycoconj J 2017 Dec 27318475
Novel substrate specificities of two lacto-N-biosidases towards β-linked galacto-N-biose-containing oligosaccharides of globo H, Gb5, and GA1.
  • Gotoh A
  • Katoh T
  • Sugiyama Y
  • Kurihara S
  • Honda Y
  • Sakurama H
  • Kambe T
  • Ashida H
  • Kitaoka M
  • Yamamoto K
  • Katayama T
Carbohydr Res 2015 May 18 25839135
Immunogenicity study of Globo H analogues with modification at the reducing or nonreducing end of the tumor antigen.
  • Lee HY
  • Chen CY
  • Tsai TI
  • Li ST
  • Lin KH
  • Cheng YY
  • Ren CT
  • Cheng TJ
  • Wu CY
  • Wong CH
J Am Chem Soc 2014 Dec 3 25371992
Effective sugar nucleotide regeneration for the large-scale enzymatic synthesis of Globo H and SSEA4.
  • Tsai TI
  • Lee HY
  • Chang SH
  • Wang CH
  • Tu YC
  • Lin YC
  • Hwang DR
  • Wu CY
  • Wong CH
J Am Chem Soc 2013 Oct 2 24044869
Expression of glycosphingolipids in lymph nodes of mice lacking TNF receptor 1: biochemical and flow cytometry analysis.
  • Marusić A
  • Markotić A
  • Kovacić N
  • Müthing J
Carbohydr Res 2004 Jan 2 14659673

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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01


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