GlyCosmos Portal

Submissions

G00061MO

Summary

GlyTouCan ID: G00061MO
IUPAC Condensed: GalNAc(b1-3)Gal(a1-4)Gal(b1-4)Glc(b1-
Motifs: Gb4 Globoside P antigen
Subsumption Level: Fully-defined saccharide
Monoisotopic Mass: 707.25

External Links

GlyGen

G00061MO

ChEBI

145578

PubChem Compound

5288889

PubChem Substance

252296009

CarbBank

3D Structures

GLYCAM: DGalpNAcb1-3DGalpa1-4DGalpb1-4DGlcpb1-OH

GlycoShape

G00061MO

Displaying 1 entry
Archetype	α	β
G99312NX	G66861DF	G00061MO

Organisms

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Organisms	Evidence
Ovis aries (sheep)	GlyTouCan(glycome-db)
Mus musculus (house mouse)	GlyTouCan(glycome-db)
Oncorhynchus mykiss (rainbow trout)	GlyTouCan(glycome-db)
Bos taurus (domestic cattle)	GlyTouCan(glycome-db)
Gallus gallus (chicken)	GlyTouCan(glycome-db)

Taxonomic Hierarchy

root

cellular organisms [inference]

Eukaryota (eucaryotes) [inference]

Opisthokonta [inference]

Metazoa (metazoans) [inference]

Eumetazoa [inference]

Bilateria [inference]

Deuterostomia [inference]

Chordata (chordates) [inference]

Craniata [inference]

Vertebrata (vertebrates) [inference]

Gnathostomata (jawed vertebrates) [inference]

Teleostomi [inference]

Euteleostomi (bony vertebrates) [inference]

Sarcopterygii [inference]

Dipnotetrapodomorpha [inference]

Tetrapoda (tetrapods) [inference]

Amniota (amniotes) [inference]

Mammalia (mammals) [inference]

Theria [inference]

Eutheria (placentals) [inference]

Boreoeutheria [inference]

Laurasiatheria [inference]

Artiodactyla (even-toed ungulates & whales) [inference]

Suina [inference]

Suidae (pigs)

Sus [inference]

Sus scrofa (pig)

Ruminantia [inference]

Pecora [inference]

Bovidae [inference]

Bovinae [inference]

Bos (cattle) [inference]

Bos taurus (domestic cattle)

Caprinae [inference]

Ovis [inference]

Ovis aries (sheep)

Carnivora (carnivores) [inference]

Caniformia [inference]

Canidae (dog, coyote, wolf, fox) [inference]

Canis [inference]

Canis lupus (gray wolf) [inference]

Canis lupus familiaris (dog)

Euarchontoglires [inference]

Glires (Rodents and rabbits) [inference]

Rodentia (rodent) [inference]

Myomorpha (mice and others) [inference]

Muroidea [inference]

Cricetidae [inference]

Cricetinae (hamsters)

Muridae [inference]

Murinae [inference]

Mus (mice) [inference]

Mus [inference]

Mus musculus (house mouse)

Rattus

Lagomorpha [inference]

Leporidae (rabbits and hares) [inference]

Oryctolagus [inference]

Oryctolagus cuniculus (rabbit)

Primates [inference]

Haplorrhini [inference]

Simiiformes [inference]

Catarrhini [inference]

Cercopithecoidea [inference]

Cercopithecidae (Old World monkeys) [inference]

Cercopithecinae [inference]

Chlorocebus [inference]

Chlorocebus aethiops (grivet)

Hominoidea (apes) [inference]

Hominidae (great apes) [inference]

Homininae [inference]

Homo [inference]

Homo sapiens (human)

Sauropsida (sauropsids) [inference]

Sauria (diapsids) [inference]

Archelosauria [inference]

Archosauria [inference]

Dinosauria [inference]

Saurischia [inference]

Theropoda [inference]

Coelurosauria [inference]

Aves (birds) [inference]

Neognathae [inference]

Galloanserae [inference]

Galliformes (landfowls) [inference]

Phasianidae (turkeys) [inference]

Phasianinae [inference]

Gallus [inference]

Gallus gallus (chicken)

Actinopterygii (ray-finned fishes) [inference]

Actinopteri [inference]

Neopterygii [inference]

Teleostei (teleost fishes) [inference]

Osteoglossocephalai [inference]

Clupeocephala [inference]

Euteleosteomorpha [inference]

Protacanthopterygii [inference]

Salmoniformes (salmons and trouts) [inference]

Salmonidae (salmonids) [inference]

Salmoninae (trouts, salmons & chars) [inference]

Oncorhynchus [inference]

Oncorhynchus mykiss (rainbow trout)

Protostomia [inference]

Spiralia [inference]

Lophotrochozoa [inference]

Mollusca (mollusks) [inference]

Bivalvia (bivalves)

Autobranchia [inference]

Heteroconchia [inference]

Palaeoheterodonta [inference]

Unionida [inference]

Unionoidea [inference]

Unionidae [inference]

Gonideinae [inference]

Sinohyriopsis [inference]

Sinohyriopsis schlegelii

Discoba [inference]

Euglenozoa [inference]

Kinetoplastea (kinetoplasts) [inference]

Metakinetoplastina [inference]

Trypanosomatida [inference]

Trypanosomatidae [inference]

Leishmaniinae [inference]

Leishmania [inference]

Leishmania mexicana species complex [inference]

Leishmania amazonensis

GlycoGene Database (GGDB)

Displaying **all 2** entries
Gene Symbol	Donor	Acceptor	Reducing terminal(Acceptor)	Product	Reducing terminal(Product)	Reference
B3GALT5	UDP-Gal	G00061MO	Cer	G99053DY	Cer	10837462
GBGT1	UDP-GalNAc	G00061MO	Cer	G80062GG	Cer	10506200

Displaying **all 3** entries
Gene Symbol	Donor	Acceptor	Reducing terminal(Acceptor)	Product	Reducing terminal(Product)	Reference
B3GALT5	UDP-Gal	G00061MO	Cer	G99053DY	Cer	10837462
B3GALNT1	UDP-GalNAc	G00059MO	Cer	G00061MO	Cer	10993897
GBGT1	UDP-GalNAc	G00061MO	Cer	G80062GG	Cer	10506200 8855242

Displaying entries **1 - 5** of 7 in total

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Gene Symbol	Donor	Acceptor	Reducing terminal(Acceptor)	Reference
B3GALT4	UDP-Gal	G00061MO	Cer	9582303
B4GALT3	UDP-Gal	G00061MO	Cer	9405390
B3GALT2	UDP-Gal	G00061MO	Cer	9582303
B3GALT1	UDP-Gal	G00061MO	Cer	9582303
B3GALNT2	UDP-GalNAc	G00061MO	Cer	14724282

KEGG BRITE Database

KEGG ID

G00094

Enzyme

Reactions

Displaying **all 5** entries
KEGG Reaction	Enzyme	Acceptor	Product
R05966	3.2.1.49	G80062GG	G00061MO
R05963	3.2.1.52	G00061MO	G00059MO
R05965	2.4.1.88	G00061MO	G80062GG
R11376	2.4.1.228	G00061MO	G33020YH
R05962	2.4.1.79	G00059MO	G00061MO

GlycoEpitope

Epitope ID: EP0073

Sequence Descriptors

GlycoCT

RES
1b:b-dglc-HEX-1:5
2b:b-dgal-HEX-1:5
3b:a-dgal-HEX-1:5
4b:b-dgal-HEX-1:5
5s:n-acetyl
LIN
1:1o(4+1)2d
2:2o(4+1)3d
3:3o(3+1)4d
4:4d(2+1)5n

WURCS

WURCS=2.0/4,4,3/[a2122h-1b_1-5][a2112h-1b_1-5][a2112h-1a_1-5][a2112h-1b_1-5_2*NCC/3=O]/1-2-3-4/a4-b1_b4-c1_c3-d1

Literature

Displaying entries **1 - 10** of 11 in total

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PubMed ID	Title	First Author	Publication Date	Source
27973758	Structural analysis and unique molecular recognition properties of a Bauhinia forficata lectin that inhibits cancer cell growth	Lubkowski J	2017 Feb	PubChem
14724282	A novel human beta1,3-N-acetylgalactosaminyltransferase that synthesizes a unique carbohydrate structure, GalNAcbeta1-3GlcNAc	Hiruma T	2004 Apr 02	PubChem
11821425	Molecular cloning and characterization of a novel UDP-GlcNAc:GalNAc-peptide beta1,3-N-acetylglucosaminyltransferase (beta 3Gn-T6), an enzyme synthesizing the core 3 structure of O-glycans	Iwai T	2002 Apr 12	PubChem
11440716	Structural Basis of the Interaction of the Pyelonephritic E. coli Adhesin to Its Human Kidney Receptor	Dodson KW	2001 Jun 15	PubChem
10837462	The beta 1,3-galactosyltransferase beta 3GalT-V is a stage-specific embryonic antigen-3 (SSEA-3) synthase	Zhou D	2000 Jul 28	PubChem
10993897	Expression cloning of human globoside synthase cDNAs. Identification of beta 3Gal-T3 as UDP-N-acetylgalactosamine:globotriaosylceramide beta 1,3-N-acetylgalactosaminyltransferase	Okajima T	2000 Dec 22	GlyGen GlycoEpitope PubChem
10506200	Characterization of the human Forssman synthetase gene. An evolving association between glycolipid synthesis and host-microbial interactions	Xu H	1999 Oct 08	PubChem
9582303	A family of human beta3-galactosyltransferases. Characterization of four members of a UDP-galactose:beta-N-acetyl-glucosamine/beta-nacetyl-galactosamine beta-1,3-galactosyltransferase family	Amado M	1998 May 22	PubChem
9405390	A family of human beta4-galactosyltransferases. Cloning and expression of two novel UDP-galactose:beta-n-acetylglucosamine beta1, 4-galactosyltransferases, beta4Gal-T2 and beta4Gal-T3	Almeida R	1997 Dec 19	PubChem
8855242	Expression cloning of Forssman glycolipid synthetase: a novel member of the histo-blood group ABO gene family.	Haslam DB	1996 Oct 01	PubChem

PubAnnotation

Displaying entries **1 - 5** of 10 in total

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Title	Authors	Source	Publication Date	PubMed ID
Molecular basis of the globoside-deficient P(k) blood group phenotype. Identification of four inactivating mutations in the UDP-N-acetylgalactosamine: globotriaosylceramide 3-beta-N-acetylgalactosaminyltransferase gene.	Hellberg A Poole J Olsson ML	J Biol Chem	2002 Aug 16	12023287
Structural relationships and sialylation among meningococcal L1, L8, and L3,7 lipooligosaccharide serotypes.	McLeod Griffiss J Brandt BL Saunders NB Zollinger W	J Biol Chem	2000 Mar 31	10734124
The beta 1,3-galactosyltransferase beta 3GalT-V is a stage-specific embryonic antigen-3 (SSEA-3) synthase.	Zhou D Henion TR Jungalwala FB Berger EG Hennet T	J Biol Chem	2000 Jul 28	10837462
Expression cloning of human globoside synthase cDNAs. Identification of beta 3Gal-T3 as UDP-N-acetylgalactosamine:globotriaosylceramide beta 1,3-N-acetylgalactosaminyltransferase.	Okajima T Nakamura Y Uchikawa M Haslam DB Numata SI Furukawa K Urano T Furukawa K	J Biol Chem	2000 Dec 22	10993897
Molecular basis for the p phenotype. Identification of distinct and multiple mutations in the alpha 1,4-galactosyltransferase gene in Swedish and Japanese individuals.	Furukawa K Iwamura K Uchikawa M Sojka BN Wiels J Okajima T Urano T Furukawa K	J Biol Chem	2000 Dec 1	10993874

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

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Other Information

Tools

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Guidelines

Summary

External Links

KEGG BRITE Database

GlycoEpitope

Sequence Descriptors

International Collaboration

Acknowledgements