Period circadian protein homolog 2
| GO Term | Evidence Code | Reference |
|---|---|---|
| negative regulation of transcription by RNA polymerase II | ||
| negative regulation of transcription by RNA polymerase II | ||
| negative regulation of transcription by RNA polymerase II | ||
| response to ischemia | ||
| neural retina development |
| GO Term | Evidence Code | Reference |
|---|---|---|
| perinuclear region of cytoplasm | ||
| Cry-Per complex |
|
|
| GO Term | Evidence Code | Reference |
|---|---|---|
| transcription cis-regulatory region binding | ||
| transcription cis-regulatory region binding | ||
| transcription corepressor binding | ||
| transcription coactivator activity |
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 566 |
|
|||
| 580 |
|
|||
| 653 |
|
|||
| 662 |
|
|||
| 668 |
|
|||
| 671 |
|
|||
| 734 |
|
|||
| 965 |
|
|||
| 983 |
|
|||
| 1180 |
|
| Pathway Name | Organism |
|---|---|
| Degradation of CRY and PER proteins | Homo sapiens |
| Phosphorylated BMAL1:CLOCK (ARNTL:CLOCK) activates expression of core clock genes | Homo sapiens |
| Phosphorylation and nuclear translocation of the CRY:PER:kinase complex | Homo sapiens |
| The CRY:PER:kinase complex represses transactivation by the BMAL:CLOCK (ARNTL:CLOCK) complex | Homo sapiens |
Tissue with high expression from Human Protein Atlas. Tissues that are highly expressed are highlighted.
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0050741 | alcohol dependence | |
| DOID:0050696 | fetal alcohol spectrum disorder | |
| DOID:9975 | cocaine dependence | |
| DOID:0050628 | advanced sleep phase syndrome | |
| DOID:0110011 | advanced sleep phase syndrome 1 |
GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.
Supported by JST NBDC Grant Number JPMJND2204
Partly supported by NIH Common Fund Grant #1U01GM125267-01
This work is licensed under Creative Commons Attribution 4.0 International
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Last updated: April 6, 2026