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Glycan Structure Repository
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Glycoconjugate Repository
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Glycomics MS raw data Repository
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Glycomics MS Repository for glycan annotations from GlycoWorkbench
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Repository for lectin-assisted multimodality data
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MIRAGE
Interleukin-6
Summary
- UniProt ID
- P05231
- Gene Symbol
-
- IFNB2
- IL6
- Gene ID
- 3569
- Organism
- Homo sapiens (human)
External Links
- GlyGen
- P05231
- PubChem
- P05231
- The Human Metabolome Database
- HMDBP02087
- Re-Glyco
- P05231
Annotation
- Keyword
-
- 3D-structure
- Acute phase
- Cytokine
- Direct protein sequencing
- Disulfide bond
- Glycoprotein
- Growth factor
- Phosphoprotein
- Reference proteome
- Secreted
- Signal
- Gene Ontology (GO)
| GO Term |
|---|
| extracellular region |
| extracellular space |
| endoplasmic reticulum lumen |
| interleukin-6 receptor complex |
| GO Term |
|---|
| cytokine activity |
| growth factor activity |
| identical protein binding |
| interleukin-6 receptor binding |
Sequence
MNSFSTSAFGPVAFSLGLLLVLPAAFPAPVPPGEDSKDVAAPHRQPLTSSERIDKQIRYILDGISALRKETCNKSNMCESSKEALAENNLNLPKMAEKDGCFQSGFNEETCLVKIITGLLEFEVYLEYLQNRFESSEEQARAVQMSTKVLIQFLQKKAKNLDAITTPDPTTNASLLTKLQAQNQWLQDMTTHLILRSFKEFLQSSLRALRQM
Glycosylation Sites
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| ADORA2B mediated anti-inflammatory cytokines production | Homo sapiens |
| CD163 mediating an anti-inflammatory response | Homo sapiens |
| Interleukin-10 signaling | Homo sapiens |
| Interleukin-4 and Interleukin-13 signaling | Homo sapiens |
| Interleukin-6 signaling | Homo sapiens |
| MAPK1 (ERK2) activation | Homo sapiens |
| MAPK3 (ERK1) activation | Homo sapiens |
| Post-translational protein phosphorylation | Homo sapiens |
| Regulation of IGF Activity by IGFBP | Homo sapiens |
| Senescence-Associated Secretory Phenotype (SASP) | Homo sapiens |
Disease
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0060688 | arteriovenous malformations of the brain | |
| DOID:0060901 | lymphoplasmacytic lymphoma | |
| DOID:0080208 | metabolic dysfunction-associated steatotic liver disease | |
| DOID:0080547 | metabolic dysfunction-associated steatohepatitis | |
| DOID:10140 | dry eye syndrome | |
| DOID:10534 | stomach cancer | |
| DOID:10608 | celiac disease | |
| DOID:10754 | otitis media | |
| DOID:10763 | hypertension | |
| DOID:10941 | intracranial aneurysm |
