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MIRAGE
Interleukin-4 receptor subunit alpha
Summary
- UniProt ID
- P24394
- Gene Symbol
-
- 582J2.1
- IL4R
- IL4RA
- Gene ID
- 3566
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- 3D-structure
- Alternative splicing
- Cell membrane
- Disulfide bond
- Glycoprotein
- Immunity
- Phosphoprotein
- Receptor
- Reference proteome
- Secreted
- Signal
- Transmembrane helix
- Gene Ontology (GO)
| GO Term |
|---|
| extracellular region |
| plasma membrane |
| receptor complex |
| nucleoplasm |
| external side of plasma membrane |
| centriolar satellite |
| GO Term |
|---|
| interleukin-4 receptor activity |
| cytokine receptor activity |
Sequence
MGWLCSGLLFPVSCLVLLQVASSGNMKVLQEPTCVSDYMSISTCEWKMNGPTNCSTELRLLYQLVFLLSEAHTCIPENNGGAGCVCHLLMDDVVSADNYTLDLWAGQQLLWKGSFKPSEHVKPRAPGNLTVHTNVSDTLLLTWSNPYPPDNYLYNHLTYAVNIWSENDPADFRIYNVTYLEPSLRIAASTLKSGISYRARVRAWAQCYNTTWSEWSPSTKWHNSYREPFEQHLLLGVSVSCIVILAVCLLCYVSITKIKKEWWDQIPNPARSRLVAIIIQDAQGSQWEKRSRGQEPAKCPHWKNCLTKLLPCFLEHNMKRDEDPHKAAKEMPFQGSGKSAWCPVEISKTVLWPESISVVRCVELFEAPVECEEEEEVEEEKGSFCASPESSRDDFQEGREGIVARLTESLFLDLLGEENGGFCQQDMGESCLLPPSGSTSAHMPWDEFPSAGPKEAPPWGKEQPLHLEPSPPASPTQSPDNLTCTETPLVIAGNPAYRSFSNSLSQSPCPRELGPDPLLARHLEEVEPEMPCVPQLSEPTTVPQPEPETWEQILRRNVLQHGAAAAPVSAPTSGYQEFVHAVEQGGTQASAVVGLGPPGEAGYKAFSSLLASSAVSPEKCGFGASSGEEGYKPFQDLIPGCPGDPAPVPVPLFTFGLDREPPRSPQSSHLPSSSPEHLGLEPGEKVEDMPKPPLPQEQATDPLVDSLGSGIVYSALTCHLCGHLKQCHGQEDGGQTPVMASPCCGCCCGDRSSPPTTPLRAPDPSPGGVPLEASLCPASLAPSGISEKSKSSSSFHPAPGNAQSSSQTPKIVNFVSVGPTYMRVS
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 53 | N-linked (GlcNAc...) asparagine | |||
| 98 | N-linked (GlcNAc...) asparagine |
|
||
| 128 | N-linked (GlcNAc...) asparagine |
|
||
| 134 | N-linked (GlcNAc...) asparagine |
|
||
| 176 | N-linked (GlcNAc...) asparagine | |||
| 209 | N-linked (GlcNAc...) asparagine |
|
G80920RR
G22310AV
G88374WZ
G62765YT
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Interleukin-4 and Interleukin-13 signaling | Homo sapiens |
Disease
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0050784 | primary progressive multiple sclerosis | |
| DOID:11204 | allergic conjunctivitis | |
| DOID:11963 | esophagitis | |
| DOID:2377 | multiple sclerosis | |
| DOID:2841 | asthma | |
| DOID:3082 | interstitial lung disease | |
| DOID:3310 | atopic dermatitis | |
| DOID:4450 | renal cell carcinoma | |
| DOID:4483 | rhinitis | |
| DOID:6543 | acne |
