Disintegrin and metalloproteinase domain-containing protein 17

Summary
UniProt ID
P78536
Gene Symbol
ADAM17 ADAM18 CSVP TACE hCG_23065
Gene ID
6868
Organism
Homo sapiens (human)
GlycoProtDB
GPDB0011762
GlyConnect
GlyGen
P78536
PubChem
P78536
The O-GlcNAc Database
P78536
O-GlcNAcAtlas
P78536
Re-Glyco
P78536
Annotation
Keyword
3D-structure Alternative splicing Cell membrane Cleavage on pair of basic residues Direct protein sequencing Disulfide bond Glycoprotein Metal-binding Metalloprotease Notch signaling pathway Phosphoprotein Proteomics identification Reference proteome SH3-binding Signal Transmembrane helix Zinc Zymogen
Gene Ontology (GO)
GO Hierarchy
GO Hierarchy
Sequence
MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC
Glycosylation Sites
Displaying entries 1 - 10 of 13 in total
Position Description PubMed ID GlyTouCan ID Source
103
  • N-linked (GlcNAc...) asparagine
105
108
157
  • N-linked (GlcNAc...) asparagine
174
  • N-linked (GlcNAc...) asparagine
264
  • N-linked (GlcNAc...) asparagine
265
452
  • N-linked (GlcNAc...) asparagine
498
  • N-linked (GlcNAc...) asparagine
539
  • N-linked (GlcNAc...) asparagine
Feature
  • ProtVista GlyGen : Glycosylation Site from GlyGen
  • ProtVista UniProt : Glycosylation Site from UniProt
Disease
Displaying all 3 entries
DO ID Disease Name Source
DOID:0050589 inflammatory bowel disease
DOID:10652 Alzheimer's disease
DOID:9352 type 2 diabetes mellitus

About Release Notes Help Feedback

Click here to visit the beta site.


International Collaboration

GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01


Logo License Policies Site Map

Contact: [email protected]

This work is licensed under Creative Commons Attribution 4.0 International


GlyCosmos Portal v4.5.0

Last updated: April 6, 2026