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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
CMP-N-acetylneuraminate-beta-1,4-galactoside alpha-2,3-sialyltransferase
Summary
- UniProt ID
- Q11203
- Gene Symbol
-
- ST3GAL3
- SIAT6
- Organism
- Homo sapiens (human)
External Links
- GlyGen
- Q11203
- PubChem
- Q11203
- The Human Metabolome Database
- HMDBP00207
- The O-GlcNAc Database
- Q11203
Annotation
- Keyword
-
- Alternative splicing
- Disease variant
- Disulfide bond
- Epilepsy
- Glycoprotein
- Glycosyltransferase
- Golgi apparatus
- Intellectual disability
- Reference proteome
- Secreted
- Signal-anchor
- Transmembrane helix
- Gene Ontology (GO)
| GO Term |
|---|
| Golgi membrane |
| extracellular region |
| Golgi cisterna membrane |
Sequence
MGLLVFVRNLLLALCLFLVLGFLYYSAWKLHLLQWEEDSNSVVLSFDSAGQTLGSEYDRLGFLLNLDSKLPAELATKYANFSEGACKPGYASALMTAIFPRFSKPAPMFLDDSFRKWARIREFVPPFGIKGQDNLIKAILSVTKEYRLTPALDSLRCRRCIIVGNGGVLANKSLGSRIDDYDIVVRLNSAPVKGFEKDVGSKTTLRITYPEGAMQRPEQYERDSLFVLAGFKWQDFKWLKYIVYKERVSASDGFWKSVATRVPKEPPEIRILNPYFIQEAAFTLIGLPFNNGLMGRGNIPTLGSVAVTMALHGCDEVAVAGFGYDMSTPNAPLHYYETVRMAAIKESWTHNIQREKEFLRKLVKARVITDLSSGI
Glycosylation Sites
G80920RR
G49108TO
G62765YT
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Defective ST3GAL3 causes MCT12 and EIEE15 | Homo sapiens |
| Glycosphingolipid biosynthesis | Homo sapiens |
| Keratan sulfate biosynthesis | Homo sapiens |
| Lewis blood group biosynthesis | Homo sapiens |
| Maturation of protein 3a | Homo sapiens |
| Maturation of protein 3a | Homo sapiens |
| Maturation of spike protein | Homo sapiens |
| Pre-NOTCH Processing in Golgi | Homo sapiens |
| Sialic acid metabolism | Homo sapiens |
| Termination of O-glycan biosynthesis | Homo sapiens |
Human Protein Atlas
Tissue with high expression from Human Protein Atlas. Tissues that are highly expressed are highlighted.
Disease
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:1470 | major depressive disorder | |
| DOID:1595 | melancholic depression | |
| DOID:1596 | depressive disorder | |
| DOID:1612 | breast cancer | |
| DOID:162 | cancer | |
| DOID:1826 | epilepsy | |
| DOID:2234 | focal epilepsy | |
| DOID:2303 | stereotypic movement disorder | |
| DOID:2481 | obsolete infantile epileptic encephalopathy | |
| DOID:2848 | obsolete melancholia |
