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MIRAGE
Glypican-2 [Cleaved into: Secreted glypican-2]

Summary
UniProt ID
Q8N158
Gene Symbol
GPC2
Gene ID
221914
Organism
Homo sapiens (human)
PubChem
Q8N158
Re-Glyco
Q8N158
Annotation
Keyword
3D-structure Cell membrane GPI-anchor Heparan sulfate Proteomics identification Reference proteome Secreted Signal
Gene Ontology (GO)
Displaying entries 1 - 5 of 8 in total
GO Term Evidence Code Reference
smoothened signaling pathway
smoothened signaling pathway
regulation of signal transduction
positive regulation of neuron projection development
positive regulation of neuron projection development
GO Hierarchy
Gene Ontology information from UniProt.
Annotation information from UniProt.
Sequence
MSALRPLLLLLLPLCPGPGPGPGSEAKVTRSCAETRQVLGARGYSLNLIPPALISGEHLRVCPQEYTCCSSETEQRLIRETEATFRGLVEDSGSFLVHTLAARHRKFDEFFLEMLSVAQHSLTQLFSHSYGRLYAQHALIFNGLFSRLRDFYGESGEGLDDTLADFWAQLLERVFPLLHPQYSFPPDYLLCLSRLASSTDGSLQPFGDSPRRLRLQITRTLVAARAFVQGLETGRNVVSEALKVPVSEGCSQALMRLIGCPLCRGVPSLMPCQGFCLNVVRGCLSSRGLEPDWGNYLDGLLILADKLQGPFSFELTAESIGVKISEGLMYLQENSAKVSAQVFQECGPPDPVPARNRRAPPPREEAGRLWSMVTEEERPTTAAGTNLHRLVWELRERLARMRGFWARLSLTVCGDSRMAADASLEAAPCWTGAGRGRYLPPVVGGSPAEQVNNPELKVDASGPDVPTRRRRLQLRAATARMKTAALGHDLDGQDADEDASGSGGGQQYADDWMAGAVAPPARPPRPPYPPRRDGSGGKGGGGSARYNQGRSRSGGASIGFHTQTILILSLSALALLGPR
  • N : N-glycosylation Site
  • ___ : Potential Sequon
Glycosylation Sites
Displaying all 5 entries
Position Description PubMed ID GlyTouCan ID Source
55
  • O-linked (Xyl...) (heparan sulfate) serine
92
  • O-linked (Xyl...) (heparan sulfate) serine
155
  • O-linked (Xyl...) (heparan sulfate) serine
500
  • O-linked (Xyl...) (heparan sulfate) serine
502
  • O-linked (Xyl...) (heparan sulfate) serine
Feature
  • ProtVista GlyGen : Glycosylation Site from GlyGen
  • ProtVista UniProt : Glycosylation Site from UniProt
Pathway
Displaying entries 1 - 10 of 16 in total
Pathway Name Organism
Attachment and Entry Homo sapiens
Defective B3GALT6 causes EDSP2 and SEMDJL1 Homo sapiens
Defective B3GAT3 causes JDSSDHD Homo sapiens
Defective B4GALT7 causes EDS, progeroid type Homo sapiens
Defective EXT1 causes exostoses 1, TRPS2 and CHDS Homo sapiens
Defective EXT2 causes exostoses 2 Homo sapiens
Dengue Virus Attachment and Entry Homo sapiens
Dengue Virus-Host Interactions Homo sapiens
Glycosaminoglycan-protein linkage region biosynthesis Homo sapiens
HS-GAG biosynthesis Homo sapiens
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GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: April 6, 2026