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MIRAGE
mRNA-decapping enzyme 1A
Summary
- UniProt ID
- Q9NPI6
- Gene Symbol
-
- DCP1A
- SMIF
- Gene ID
- 55802
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- 3D-structure
- Alternative splicing
- Cytoplasm
- Hydrolase
- Methylation
- Nonsense-mediated mRNA decay
- Nucleus
- Phosphoprotein
- Reference proteome
- Gene Ontology (GO)
| GO Term |
|---|
| 5'-(N(7)-methylguanosine 5'-triphospho)-[mRNA] hydrolase activity |
| mRNA binding |
| kinesin binding |
| identical protein binding |
| enzyme activator activity |
Sequence
MEALSRAGQEMSLAALKQHDPYITSIADLTGQVALYTFCPKANQWEKTDIEGTLFVYRRSASPYHGFTIVNRLNMHNLVEPVNKDLEFQLHEPFLLYRNASLSIYSIWFYDKNDCHRIAKLMADVVEEETRRSQQAARDKQSPSQANGCSDHRPIDILEMLSRAKDEYERNQMGDSNISSPGLQPSTQLSNLGSTETLEEMPSGSQDKSAPSGHKHLTVEELFGTSLPKEQPAVVGLDSEEMERLPGDASQKEPNSFLPFPFEQLGGAPQSETLGVPSAAHHSVQPEITTPVLITPASITQSNEKHAPTYTIPLSPVLSPTLPAEAPTAQVPPSLPRNSTMMQAVKTTPRQRSPLLNQPVPELSHASLIANQSPFRAPLNVTNTAGTSLPSVDLLQKLRLTPQHDQIQTQPLGKGAMVASFSPAAGQLATPESFIEPPSKTAAARVAASASLSNMVLAPLQSMQQNQDPEVFVQPKVLSSAIPVAGAPLVTATTTAVSSVLLAPSVFQQTVTRSSDLERKASSPSPLTIGTPESQRKPSIILSKSQLQDTLIHLIKNDSSFLSTLHEVYLQVLTKNKDNHNL
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 239 |
|
|||
| 380 |
|
|||
| 382 |
|
|||
| 388 |
|
|||
| 491 |
|
|||
| 493 |
|
|||
| 494 |
|
|||
| 495 |
|
|||
| 498 |
|
|||
| 499 |
|
G49108TO
G59324HL
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA | Homo sapiens |
| Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) | Homo sapiens |
| Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA | Homo sapiens |
| mRNA decay by 5' to 3' exoribonuclease | Homo sapiens |
