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Toll-like receptor 9

Summary

UniProt ID: Q9NR96
Gene Symbol: TLR9 UNQ5798/PRO19605
Gene ID: 54106
Organism: Homo sapiens (human)

External Links

GlyGen: Q9NR96
PubChem: Q9NR96
The Human Metabolome Database: HMDBP02761
Re-Glyco: Q9NR96

Annotation

Keyword: 3D-structure Alternative splicing Cytoplasmic vesicle Disulfide bond Endoplasmic reticulum Endosome Glycoprotein Golgi apparatus Inflammatory response Innate immunity Leucine-rich repeat Lysosome Palmitate Proteomics identification Receptor Reference proteome Repeat Signal Transmembrane helix

Gene Ontology (GO)

Displaying entries **1 - 5** of 62 in total

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GO Term	Evidence Code	Reference
microglial cell activation	IEA	GO_REF
toll-like receptor signaling pathway	IDA	PMID
toll-like receptor signaling pathway	IBA	GO_REF
toll-like receptor signaling pathway	IEA	GO_REF
positive regulation of immunoglobulin production	IDA	PMID

GO Hierarchy

biological process

immune system process [inference]

activation of immune response [inference]

activation of innate immune response [inference]

innate immune response-activating signaling pathway [inference]

pattern recognition receptor signaling pathway [inference]

toll-like receptor signaling pathway

MyD88-dependent toll-like receptor signaling pathway

cytoplasmic pattern recognition receptor signaling pathway [inference]

endolysosomal toll-like receptor signaling pathway [inference]

toll-like receptor 9 signaling pathway

immune response-activating signaling pathway [inference]

innate immune response-activating signaling pathway [inference]

pattern recognition receptor signaling pathway [inference]

toll-like receptor signaling pathway

MyD88-dependent toll-like receptor signaling pathway

cytoplasmic pattern recognition receptor signaling pathway [inference]

endolysosomal toll-like receptor signaling pathway [inference]

toll-like receptor 9 signaling pathway

immune response [inference]

innate immune response

leukocyte activation [inference]

leukocyte activation involved in inflammatory response [inference]

microglial cell activation

myeloid leukocyte activation [inference]

macrophage activation [inference]

microglial cell activation

cellular process [inference]

cell activation [inference]

leukocyte activation [inference]

leukocyte activation involved in inflammatory response [inference]

microglial cell activation

myeloid leukocyte activation [inference]

macrophage activation [inference]

microglial cell activation

glial cell activation [inference]

microglial cell activation

signal transduction [inference]

immune response-regulating signaling pathway [inference]

immune response-activating signaling pathway [inference]

innate immune response-activating signaling pathway [inference]

pattern recognition receptor signaling pathway [inference]

toll-like receptor signaling pathway

MyD88-dependent toll-like receptor signaling pathway

cytoplasmic pattern recognition receptor signaling pathway [inference]

endolysosomal toll-like receptor signaling pathway [inference]

toll-like receptor 9 signaling pathway

intracellular signal transduction [inference]

intracellular receptor signaling pathway [inference]

cytoplasmic pattern recognition receptor signaling pathway [inference]

endolysosomal toll-like receptor signaling pathway [inference]

toll-like receptor 9 signaling pathway

intracellular signaling cassette [inference]

canonical NF-kappaB signal transduction

cellular response to stimulus [inference]

cellular response to chemical stimulus [inference]

cellular response to metal ion

cellular response to lipid [inference]

cellular response to lipopolysaccharide

cellular response to nitrogen compound [inference]

cellular response to chloroquine

cellular response to oxygen-containing compound [inference]

cellular response to lipopolysaccharide

cellular response to biotic stimulus [inference]

cellular response to molecule of bacterial origin [inference]

cellular response to lipopolysaccharide

reproductive process [inference]

developmental process involved in reproduction [inference]

reproductive structure development [inference]

gonad development [inference]

male gonad development

multicellular organismal process [inference]

cell activation [inference]

leukocyte activation [inference]

leukocyte activation involved in inflammatory response [inference]

microglial cell activation

myeloid leukocyte activation [inference]

macrophage activation [inference]

microglial cell activation

glial cell activation [inference]

microglial cell activation

system process [inference]

digestive system process [inference]

maintenance of gastrointestinal epithelium

multicellular organismal-level homeostasis [inference]

anatomical structure homeostasis [inference]

tissue homeostasis [inference]

epithelial structure maintenance [inference]

maintenance of gastrointestinal epithelium

developmental process [inference]

developmental process involved in reproduction [inference]

reproductive structure development [inference]

gonad development [inference]

male gonad development

anatomical structure development [inference]

animal organ development [inference]

gonad development [inference]

male gonad development

reproductive structure development [inference]

gonad development [inference]

male gonad development

homeostatic process [inference]

multicellular organismal-level homeostasis [inference]

anatomical structure homeostasis [inference]

tissue homeostasis [inference]

epithelial structure maintenance [inference]

maintenance of gastrointestinal epithelium

biological process involved in interspecies interaction between organisms [inference]

response to other organism [inference]

response to virus [inference]

defense response to virus

response to bacterium [inference]

defense response to bacterium

defense response to Gram-negative bacterium

defense response to other organism [inference]

defense response to symbiont [inference]

innate immune response

response to stimulus [inference]

response to stress [inference]

defense response [inference]

defense response to bacterium

defense response to Gram-negative bacterium

defense response to virus

defense response to other organism [inference]

defense response to symbiont [inference]

innate immune response

immune response [inference]

innate immune response

response to external stimulus [inference]

response to external biotic stimulus [inference]

response to molecule of bacterial origin [inference]

detection of molecule of bacterial origin

response to lipopolysaccharide [inference]

cellular response to lipopolysaccharide

cellular response to molecule of bacterial origin [inference]

cellular response to lipopolysaccharide

response to other organism [inference]

response to virus [inference]

defense response to virus

response to bacterium [inference]

defense response to bacterium

defense response to Gram-negative bacterium

defense response to other organism [inference]

defense response to symbiont [inference]

innate immune response

detection of external biotic stimulus [inference]

detection of molecule of bacterial origin

response to biotic stimulus [inference]

detection of biotic stimulus [inference]

detection of external biotic stimulus [inference]

detection of molecule of bacterial origin

response to external biotic stimulus [inference]

response to molecule of bacterial origin [inference]

detection of molecule of bacterial origin

response to lipopolysaccharide [inference]

cellular response to lipopolysaccharide

cellular response to molecule of bacterial origin [inference]

cellular response to lipopolysaccharide

response to other organism [inference]

response to virus [inference]

defense response to virus

response to bacterium [inference]

defense response to bacterium

defense response to Gram-negative bacterium

defense response to other organism [inference]

defense response to symbiont [inference]

innate immune response

detection of external biotic stimulus [inference]

detection of molecule of bacterial origin

cellular response to biotic stimulus [inference]

cellular response to molecule of bacterial origin [inference]

cellular response to lipopolysaccharide

response to chemical [inference]

response to metal ion [inference]

cellular response to metal ion

response to lipid [inference]

response to lipopolysaccharide [inference]

cellular response to lipopolysaccharide

cellular response to lipid [inference]

cellular response to lipopolysaccharide

cellular response to chemical stimulus [inference]

cellular response to metal ion

cellular response to lipid [inference]

cellular response to lipopolysaccharide

cellular response to nitrogen compound [inference]

cellular response to chloroquine

cellular response to oxygen-containing compound [inference]

cellular response to lipopolysaccharide

response to nitrogen compound [inference]

cellular response to nitrogen compound [inference]

cellular response to chloroquine

response to chloroquine [inference]

cellular response to chloroquine

response to oxygen-containing compound [inference]

response to lipopolysaccharide [inference]

cellular response to lipopolysaccharide

cellular response to oxygen-containing compound [inference]

cellular response to lipopolysaccharide

detection of stimulus [inference]

detection of chemical stimulus [inference]

detection of molecule of bacterial origin

detection of biotic stimulus [inference]

detection of external biotic stimulus [inference]

detection of molecule of bacterial origin

cellular response to stimulus [inference]

cellular response to chemical stimulus [inference]

cellular response to metal ion

cellular response to lipid [inference]

cellular response to lipopolysaccharide

cellular response to nitrogen compound [inference]

cellular response to chloroquine

cellular response to oxygen-containing compound [inference]

cellular response to lipopolysaccharide

cellular response to biotic stimulus [inference]

cellular response to molecule of bacterial origin [inference]

cellular response to lipopolysaccharide

biological regulation [inference]

regulation of biological process [inference]

regulation of immune system process [inference]

positive regulation of immune system process [inference]

positive regulation of leukocyte activation [inference]

positive regulation of lymphocyte activation [inference]

positive regulation of lymphocyte proliferation [inference]

positive regulation of B cell proliferation

positive regulation of B cell activation

positive regulation of B cell proliferation

positive regulation of immune effector process [inference]

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of immunoglobulin production

positive regulation of immune response [inference]

activation of immune response [inference]

activation of innate immune response [inference]

innate immune response-activating signaling pathway [inference]

pattern recognition receptor signaling pathway [inference]

toll-like receptor signaling pathway

MyD88-dependent toll-like receptor signaling pathway

cytoplasmic pattern recognition receptor signaling pathway [inference]

endolysosomal toll-like receptor signaling pathway [inference]

toll-like receptor 9 signaling pathway

immune response-activating signaling pathway [inference]

innate immune response-activating signaling pathway [inference]

pattern recognition receptor signaling pathway [inference]

toll-like receptor signaling pathway

MyD88-dependent toll-like receptor signaling pathway

cytoplasmic pattern recognition receptor signaling pathway [inference]

endolysosomal toll-like receptor signaling pathway [inference]

toll-like receptor 9 signaling pathway

positive regulation of innate immune response [inference]

activation of innate immune response [inference]

innate immune response-activating signaling pathway [inference]

pattern recognition receptor signaling pathway [inference]

toll-like receptor signaling pathway

MyD88-dependent toll-like receptor signaling pathway

cytoplasmic pattern recognition receptor signaling pathway [inference]

endolysosomal toll-like receptor signaling pathway [inference]

toll-like receptor 9 signaling pathway

positive regulation of pattern recognition receptor signaling pathway [inference]

positive regulation of toll-like receptor 9 signaling pathway

regulation of leukocyte activation [inference]

positive regulation of leukocyte activation [inference]

positive regulation of lymphocyte activation [inference]

positive regulation of lymphocyte proliferation [inference]

positive regulation of B cell proliferation

positive regulation of B cell activation

positive regulation of B cell proliferation

regulation of lymphocyte activation [inference]

regulation of lymphocyte differentiation [inference]

regulation of B cell differentiation

regulation of lymphocyte proliferation [inference]

regulation of B cell proliferation [inference]

positive regulation of B cell proliferation

positive regulation of lymphocyte proliferation [inference]

positive regulation of B cell proliferation

regulation of B cell activation [inference]

regulation of B cell proliferation [inference]

positive regulation of B cell proliferation

regulation of B cell differentiation

positive regulation of B cell activation

positive regulation of B cell proliferation

positive regulation of lymphocyte activation [inference]

positive regulation of lymphocyte proliferation [inference]

positive regulation of B cell proliferation

positive regulation of B cell activation

positive regulation of B cell proliferation

regulation of immune effector process [inference]

positive regulation of immune effector process [inference]

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of immunoglobulin production

regulation of production of molecular mediator of immune response [inference]

regulation of immunoglobulin production [inference]

positive regulation of immunoglobulin production

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of immunoglobulin production

regulation of cytokine production involved in immune response [inference]

regulation of dendritic cell cytokine production

regulation of leukocyte mediated immunity [inference]

regulation of dendritic cell cytokine production

regulation of immune response [inference]

immune response-regulating signaling pathway [inference]

immune response-activating signaling pathway [inference]

innate immune response-activating signaling pathway [inference]

pattern recognition receptor signaling pathway [inference]

toll-like receptor signaling pathway

MyD88-dependent toll-like receptor signaling pathway

cytoplasmic pattern recognition receptor signaling pathway [inference]

endolysosomal toll-like receptor signaling pathway [inference]

toll-like receptor 9 signaling pathway

regulation of innate immune response [inference]

positive regulation of innate immune response [inference]

activation of innate immune response [inference]

innate immune response-activating signaling pathway [inference]

pattern recognition receptor signaling pathway [inference]

toll-like receptor signaling pathway

MyD88-dependent toll-like receptor signaling pathway

cytoplasmic pattern recognition receptor signaling pathway [inference]

endolysosomal toll-like receptor signaling pathway [inference]

toll-like receptor 9 signaling pathway

positive regulation of pattern recognition receptor signaling pathway [inference]

positive regulation of toll-like receptor 9 signaling pathway

regulation of pattern recognition receptor signaling pathway [inference]

regulation of cytoplasmic pattern recognition receptor signaling pathway [inference]

regulation of toll-like receptor 9 signaling pathway [inference]

positive regulation of toll-like receptor 9 signaling pathway

positive regulation of pattern recognition receptor signaling pathway [inference]

positive regulation of toll-like receptor 9 signaling pathway

positive regulation of immune response [inference]

activation of immune response [inference]

activation of innate immune response [inference]

innate immune response-activating signaling pathway [inference]

pattern recognition receptor signaling pathway [inference]

toll-like receptor signaling pathway

MyD88-dependent toll-like receptor signaling pathway

cytoplasmic pattern recognition receptor signaling pathway [inference]

endolysosomal toll-like receptor signaling pathway [inference]

toll-like receptor 9 signaling pathway

immune response-activating signaling pathway [inference]

innate immune response-activating signaling pathway [inference]

pattern recognition receptor signaling pathway [inference]

toll-like receptor signaling pathway

MyD88-dependent toll-like receptor signaling pathway

cytoplasmic pattern recognition receptor signaling pathway [inference]

endolysosomal toll-like receptor signaling pathway [inference]

toll-like receptor 9 signaling pathway

positive regulation of innate immune response [inference]

activation of innate immune response [inference]

innate immune response-activating signaling pathway [inference]

pattern recognition receptor signaling pathway [inference]

toll-like receptor signaling pathway

MyD88-dependent toll-like receptor signaling pathway

cytoplasmic pattern recognition receptor signaling pathway [inference]

endolysosomal toll-like receptor signaling pathway [inference]

toll-like receptor 9 signaling pathway

positive regulation of pattern recognition receptor signaling pathway [inference]

positive regulation of toll-like receptor 9 signaling pathway

regulation of hemopoiesis [inference]

regulation of leukocyte differentiation [inference]

regulation of lymphocyte differentiation [inference]

regulation of B cell differentiation

regulation of signaling [inference]

regulation of signal transduction [inference]

positive regulation of signal transduction [inference]

positive regulation of pattern recognition receptor signaling pathway [inference]

positive regulation of toll-like receptor 9 signaling pathway

positive regulation of intracellular signal transduction [inference]

positive regulation of MAPK cascade

positive regulation of JNK cascade

negative regulation of signal transduction [inference]

negative regulation of intracellular signal transduction [inference]

negative regulation of MAPK cascade [inference]

negative regulation of ERK1 and ERK2 cascade

regulation of pattern recognition receptor signaling pathway [inference]

regulation of cytoplasmic pattern recognition receptor signaling pathway [inference]

regulation of toll-like receptor 9 signaling pathway [inference]

positive regulation of toll-like receptor 9 signaling pathway

positive regulation of pattern recognition receptor signaling pathway [inference]

positive regulation of toll-like receptor 9 signaling pathway

regulation of intracellular signal transduction [inference]

regulation of cytoplasmic pattern recognition receptor signaling pathway [inference]

regulation of toll-like receptor 9 signaling pathway [inference]

positive regulation of toll-like receptor 9 signaling pathway

regulation of canonical NF-kappaB signal transduction [inference]

positive regulation of canonical NF-kappaB signal transduction

regulation of MAPK cascade [inference]

negative regulation of MAPK cascade [inference]

negative regulation of ERK1 and ERK2 cascade

positive regulation of MAPK cascade

positive regulation of JNK cascade

regulation of JNK cascade [inference]

positive regulation of JNK cascade

regulation of ERK1 and ERK2 cascade [inference]

negative regulation of ERK1 and ERK2 cascade

negative regulation of intracellular signal transduction [inference]

negative regulation of MAPK cascade [inference]

negative regulation of ERK1 and ERK2 cascade

positive regulation of intracellular signal transduction [inference]

positive regulation of MAPK cascade

positive regulation of JNK cascade

positive regulation of signaling [inference]

positive regulation of signal transduction [inference]

positive regulation of pattern recognition receptor signaling pathway [inference]

positive regulation of toll-like receptor 9 signaling pathway

positive regulation of intracellular signal transduction [inference]

positive regulation of MAPK cascade

positive regulation of JNK cascade

negative regulation of signaling [inference]

negative regulation of signal transduction [inference]

negative regulation of intracellular signal transduction [inference]

negative regulation of MAPK cascade [inference]

negative regulation of ERK1 and ERK2 cascade

regulation of localization [inference]

regulation of transport [inference]

regulation of transmembrane transport [inference]

regulation of transmembrane transporter activity [inference]

negative regulation of ion transmembrane transporter activity [inference]

negative regulation of calcium ion transmembrane transporter activity [inference]

negative regulation of ATPase-coupled calcium transmembrane transporter activity

regulation of ATPase-coupled calcium transmembrane transporter activity [inference]

negative regulation of ATPase-coupled calcium transmembrane transporter activity

negative regulation of transmembrane transport [inference]

negative regulation of monoatomic ion transmembrane transport [inference]

negative regulation of ion transmembrane transporter activity [inference]

negative regulation of calcium ion transmembrane transporter activity [inference]

negative regulation of ATPase-coupled calcium transmembrane transporter activity

negative regulation of cation transmembrane transport [inference]

negative regulation of calcium ion transmembrane transport [inference]

negative regulation of calcium ion transmembrane transporter activity [inference]

negative regulation of ATPase-coupled calcium transmembrane transporter activity

regulation of monoatomic ion transmembrane transport [inference]

negative regulation of monoatomic ion transmembrane transport [inference]

negative regulation of ion transmembrane transporter activity [inference]

negative regulation of calcium ion transmembrane transporter activity [inference]

negative regulation of ATPase-coupled calcium transmembrane transporter activity

negative regulation of cation transmembrane transport [inference]

negative regulation of calcium ion transmembrane transport [inference]

negative regulation of calcium ion transmembrane transporter activity [inference]

negative regulation of ATPase-coupled calcium transmembrane transporter activity

regulation of monoatomic cation transmembrane transport [inference]

regulation of calcium ion transmembrane transport [inference]

negative regulation of calcium ion transmembrane transport [inference]

negative regulation of calcium ion transmembrane transporter activity [inference]

negative regulation of ATPase-coupled calcium transmembrane transporter activity

negative regulation of cation transmembrane transport [inference]

negative regulation of calcium ion transmembrane transport [inference]

negative regulation of calcium ion transmembrane transporter activity [inference]

negative regulation of ATPase-coupled calcium transmembrane transporter activity

regulation of monoatomic ion transport [inference]

regulation of metal ion transport [inference]

regulation of calcium ion transport [inference]

negative regulation of calcium ion transport [inference]

negative regulation of calcium ion transmembrane transport [inference]

negative regulation of calcium ion transmembrane transporter activity [inference]

negative regulation of ATPase-coupled calcium transmembrane transporter activity

regulation of calcium ion transmembrane transport [inference]

negative regulation of calcium ion transmembrane transport [inference]

negative regulation of calcium ion transmembrane transporter activity [inference]

negative regulation of ATPase-coupled calcium transmembrane transporter activity

regulation of monoatomic ion transmembrane transport [inference]

negative regulation of monoatomic ion transmembrane transport [inference]

negative regulation of ion transmembrane transporter activity [inference]

negative regulation of calcium ion transmembrane transporter activity [inference]

negative regulation of ATPase-coupled calcium transmembrane transporter activity

negative regulation of cation transmembrane transport [inference]

negative regulation of calcium ion transmembrane transport [inference]

negative regulation of calcium ion transmembrane transporter activity [inference]

negative regulation of ATPase-coupled calcium transmembrane transporter activity

regulation of monoatomic cation transmembrane transport [inference]

regulation of calcium ion transmembrane transport [inference]

negative regulation of calcium ion transmembrane transport [inference]

negative regulation of calcium ion transmembrane transporter activity [inference]

negative regulation of ATPase-coupled calcium transmembrane transporter activity

negative regulation of cation transmembrane transport [inference]

negative regulation of calcium ion transmembrane transport [inference]

negative regulation of calcium ion transmembrane transporter activity [inference]

negative regulation of ATPase-coupled calcium transmembrane transporter activity

negative regulation of monoatomic ion transport [inference]

negative regulation of monoatomic ion transmembrane transport [inference]

negative regulation of ion transmembrane transporter activity [inference]

negative regulation of calcium ion transmembrane transporter activity [inference]

negative regulation of ATPase-coupled calcium transmembrane transporter activity

negative regulation of cation transmembrane transport [inference]

negative regulation of calcium ion transmembrane transport [inference]

negative regulation of calcium ion transmembrane transporter activity [inference]

negative regulation of ATPase-coupled calcium transmembrane transporter activity

negative regulation of calcium ion transport [inference]

negative regulation of calcium ion transmembrane transport [inference]

negative regulation of calcium ion transmembrane transporter activity [inference]

negative regulation of ATPase-coupled calcium transmembrane transporter activity

negative regulation of transport [inference]

negative regulation of transporter activity [inference]

negative regulation of ion transmembrane transporter activity [inference]

negative regulation of calcium ion transmembrane transporter activity [inference]

negative regulation of ATPase-coupled calcium transmembrane transporter activity

negative regulation of transmembrane transport [inference]

negative regulation of monoatomic ion transmembrane transport [inference]

negative regulation of ion transmembrane transporter activity [inference]

negative regulation of calcium ion transmembrane transporter activity [inference]

negative regulation of ATPase-coupled calcium transmembrane transporter activity

negative regulation of cation transmembrane transport [inference]

negative regulation of calcium ion transmembrane transport [inference]

negative regulation of calcium ion transmembrane transporter activity [inference]

negative regulation of ATPase-coupled calcium transmembrane transporter activity

negative regulation of monoatomic ion transport [inference]

negative regulation of monoatomic ion transmembrane transport [inference]

negative regulation of ion transmembrane transporter activity [inference]

negative regulation of calcium ion transmembrane transporter activity [inference]

negative regulation of ATPase-coupled calcium transmembrane transporter activity

negative regulation of cation transmembrane transport [inference]

negative regulation of calcium ion transmembrane transport [inference]

negative regulation of calcium ion transmembrane transporter activity [inference]

negative regulation of ATPase-coupled calcium transmembrane transporter activity

negative regulation of calcium ion transport [inference]

negative regulation of calcium ion transmembrane transport [inference]

negative regulation of calcium ion transmembrane transporter activity [inference]

negative regulation of ATPase-coupled calcium transmembrane transporter activity

positive regulation of biological process [inference]

positive regulation of immune system process [inference]

positive regulation of leukocyte activation [inference]

positive regulation of lymphocyte activation [inference]

positive regulation of lymphocyte proliferation [inference]

positive regulation of B cell proliferation

positive regulation of B cell activation

positive regulation of B cell proliferation

positive regulation of immune effector process [inference]

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of immunoglobulin production

positive regulation of immune response [inference]

activation of immune response [inference]

activation of innate immune response [inference]

innate immune response-activating signaling pathway [inference]

pattern recognition receptor signaling pathway [inference]

toll-like receptor signaling pathway

MyD88-dependent toll-like receptor signaling pathway

cytoplasmic pattern recognition receptor signaling pathway [inference]

endolysosomal toll-like receptor signaling pathway [inference]

toll-like receptor 9 signaling pathway

immune response-activating signaling pathway [inference]

innate immune response-activating signaling pathway [inference]

pattern recognition receptor signaling pathway [inference]

toll-like receptor signaling pathway

MyD88-dependent toll-like receptor signaling pathway

cytoplasmic pattern recognition receptor signaling pathway [inference]

endolysosomal toll-like receptor signaling pathway [inference]

toll-like receptor 9 signaling pathway

positive regulation of innate immune response [inference]

activation of innate immune response [inference]

innate immune response-activating signaling pathway [inference]

pattern recognition receptor signaling pathway [inference]

toll-like receptor signaling pathway

MyD88-dependent toll-like receptor signaling pathway

cytoplasmic pattern recognition receptor signaling pathway [inference]

endolysosomal toll-like receptor signaling pathway [inference]

toll-like receptor 9 signaling pathway

positive regulation of pattern recognition receptor signaling pathway [inference]

positive regulation of toll-like receptor 9 signaling pathway

positive regulation of signaling [inference]

positive regulation of signal transduction [inference]

positive regulation of pattern recognition receptor signaling pathway [inference]

positive regulation of toll-like receptor 9 signaling pathway

positive regulation of intracellular signal transduction [inference]

positive regulation of MAPK cascade

positive regulation of JNK cascade

positive regulation of cellular process [inference]

positive regulation of cell population proliferation [inference]

positive regulation of leukocyte proliferation [inference]

positive regulation of mononuclear cell proliferation [inference]

positive regulation of lymphocyte proliferation [inference]

positive regulation of B cell proliferation

positive regulation of metabolic process [inference]

positive regulation of biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

positive regulation of cytokine production [inference]

positive regulation of type I interferon production [inference]

positive regulation of tumor necrosis factor superfamily cytokine production [inference]

positive regulation of tumor necrosis factor production

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of immunoglobulin production

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of catabolic process [inference]

positive regulation of autophagy

positive regulation of macromolecule metabolic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

positive regulation of cytokine production [inference]

positive regulation of type I interferon production [inference]

positive regulation of tumor necrosis factor superfamily cytokine production [inference]

positive regulation of tumor necrosis factor production

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of immunoglobulin production

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of protein metabolic process [inference]

positive regulation of granulocyte macrophage colony-stimulating factor production

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of cell communication [inference]

positive regulation of signal transduction [inference]

positive regulation of pattern recognition receptor signaling pathway [inference]

positive regulation of toll-like receptor 9 signaling pathway

positive regulation of intracellular signal transduction [inference]

positive regulation of MAPK cascade

positive regulation of JNK cascade

positive regulation of cell differentiation [inference]

positive regulation of cell development [inference]

positive regulation of intestinal epithelial cell development

positive regulation of cell activation [inference]

positive regulation of leukocyte activation [inference]

positive regulation of lymphocyte activation [inference]

positive regulation of lymphocyte proliferation [inference]

positive regulation of B cell proliferation

positive regulation of B cell activation

positive regulation of B cell proliferation

positive regulation of response to stimulus [inference]

positive regulation of response to biotic stimulus [inference]

positive regulation of innate immune response [inference]

activation of innate immune response [inference]

innate immune response-activating signaling pathway [inference]

pattern recognition receptor signaling pathway [inference]

toll-like receptor signaling pathway

MyD88-dependent toll-like receptor signaling pathway

cytoplasmic pattern recognition receptor signaling pathway [inference]

endolysosomal toll-like receptor signaling pathway [inference]

toll-like receptor 9 signaling pathway

positive regulation of pattern recognition receptor signaling pathway [inference]

positive regulation of toll-like receptor 9 signaling pathway

positive regulation of signal transduction [inference]

positive regulation of pattern recognition receptor signaling pathway [inference]

positive regulation of toll-like receptor 9 signaling pathway

positive regulation of intracellular signal transduction [inference]

positive regulation of MAPK cascade

positive regulation of JNK cascade

positive regulation of defense response [inference]

positive regulation of innate immune response [inference]

activation of innate immune response [inference]

innate immune response-activating signaling pathway [inference]

pattern recognition receptor signaling pathway [inference]

toll-like receptor signaling pathway

MyD88-dependent toll-like receptor signaling pathway

cytoplasmic pattern recognition receptor signaling pathway [inference]

endolysosomal toll-like receptor signaling pathway [inference]

toll-like receptor 9 signaling pathway

positive regulation of pattern recognition receptor signaling pathway [inference]

positive regulation of toll-like receptor 9 signaling pathway

positive regulation of inflammatory response

positive regulation of response to external stimulus [inference]

positive regulation of innate immune response [inference]

activation of innate immune response [inference]

innate immune response-activating signaling pathway [inference]

pattern recognition receptor signaling pathway [inference]

toll-like receptor signaling pathway

MyD88-dependent toll-like receptor signaling pathway

cytoplasmic pattern recognition receptor signaling pathway [inference]

endolysosomal toll-like receptor signaling pathway [inference]

toll-like receptor 9 signaling pathway

positive regulation of pattern recognition receptor signaling pathway [inference]

positive regulation of toll-like receptor 9 signaling pathway

positive regulation of inflammatory response

positive regulation of immune response [inference]

activation of immune response [inference]

activation of innate immune response [inference]

innate immune response-activating signaling pathway [inference]

pattern recognition receptor signaling pathway [inference]

toll-like receptor signaling pathway

MyD88-dependent toll-like receptor signaling pathway

cytoplasmic pattern recognition receptor signaling pathway [inference]

endolysosomal toll-like receptor signaling pathway [inference]

toll-like receptor 9 signaling pathway

immune response-activating signaling pathway [inference]

innate immune response-activating signaling pathway [inference]

pattern recognition receptor signaling pathway [inference]

toll-like receptor signaling pathway

MyD88-dependent toll-like receptor signaling pathway

cytoplasmic pattern recognition receptor signaling pathway [inference]

endolysosomal toll-like receptor signaling pathway [inference]

toll-like receptor 9 signaling pathway

positive regulation of innate immune response [inference]

activation of innate immune response [inference]

innate immune response-activating signaling pathway [inference]

pattern recognition receptor signaling pathway [inference]

toll-like receptor signaling pathway

MyD88-dependent toll-like receptor signaling pathway

cytoplasmic pattern recognition receptor signaling pathway [inference]

endolysosomal toll-like receptor signaling pathway [inference]

toll-like receptor 9 signaling pathway

positive regulation of pattern recognition receptor signaling pathway [inference]

positive regulation of toll-like receptor 9 signaling pathway

positive regulation of developmental process [inference]

positive regulation of cell differentiation [inference]

positive regulation of cell development [inference]

positive regulation of intestinal epithelial cell development

positive regulation of multicellular organismal process [inference]

positive regulation of cytokine production [inference]

positive regulation of type I interferon production [inference]

positive regulation of tumor necrosis factor superfamily cytokine production [inference]

positive regulation of tumor necrosis factor production

positive regulation of cell activation [inference]

positive regulation of leukocyte activation [inference]

positive regulation of lymphocyte activation [inference]

positive regulation of lymphocyte proliferation [inference]

positive regulation of B cell proliferation

positive regulation of B cell activation

positive regulation of B cell proliferation

positive regulation of intestinal epithelial cell development

negative regulation of biological process [inference]

negative regulation of signaling [inference]

negative regulation of signal transduction [inference]

negative regulation of intracellular signal transduction [inference]

negative regulation of MAPK cascade [inference]

negative regulation of ERK1 and ERK2 cascade

negative regulation of cellular process [inference]

negative regulation of cell communication [inference]

negative regulation of signal transduction [inference]

negative regulation of intracellular signal transduction [inference]

negative regulation of MAPK cascade [inference]

negative regulation of ERK1 and ERK2 cascade

negative regulation of transmembrane transport [inference]

negative regulation of monoatomic ion transmembrane transport [inference]

negative regulation of ion transmembrane transporter activity [inference]

negative regulation of calcium ion transmembrane transporter activity [inference]

negative regulation of ATPase-coupled calcium transmembrane transporter activity

negative regulation of cation transmembrane transport [inference]

negative regulation of calcium ion transmembrane transport [inference]

negative regulation of calcium ion transmembrane transporter activity [inference]

negative regulation of ATPase-coupled calcium transmembrane transporter activity

negative regulation of response to stimulus [inference]

negative regulation of signal transduction [inference]

negative regulation of intracellular signal transduction [inference]

negative regulation of MAPK cascade [inference]

negative regulation of ERK1 and ERK2 cascade

negative regulation of transport [inference]

negative regulation of transporter activity [inference]

negative regulation of ion transmembrane transporter activity [inference]

negative regulation of calcium ion transmembrane transporter activity [inference]

negative regulation of ATPase-coupled calcium transmembrane transporter activity

negative regulation of transmembrane transport [inference]

negative regulation of monoatomic ion transmembrane transport [inference]

negative regulation of ion transmembrane transporter activity [inference]

negative regulation of calcium ion transmembrane transporter activity [inference]

negative regulation of ATPase-coupled calcium transmembrane transporter activity

negative regulation of cation transmembrane transport [inference]

negative regulation of calcium ion transmembrane transport [inference]

negative regulation of calcium ion transmembrane transporter activity [inference]

negative regulation of ATPase-coupled calcium transmembrane transporter activity

negative regulation of monoatomic ion transport [inference]

negative regulation of monoatomic ion transmembrane transport [inference]

negative regulation of ion transmembrane transporter activity [inference]

negative regulation of calcium ion transmembrane transporter activity [inference]

negative regulation of ATPase-coupled calcium transmembrane transporter activity

negative regulation of cation transmembrane transport [inference]

negative regulation of calcium ion transmembrane transport [inference]

negative regulation of calcium ion transmembrane transporter activity [inference]

negative regulation of ATPase-coupled calcium transmembrane transporter activity

negative regulation of calcium ion transport [inference]

negative regulation of calcium ion transmembrane transport [inference]

negative regulation of calcium ion transmembrane transporter activity [inference]

negative regulation of ATPase-coupled calcium transmembrane transporter activity

regulation of response to stimulus [inference]

regulation of response to biotic stimulus [inference]

positive regulation of response to biotic stimulus [inference]

positive regulation of innate immune response [inference]

activation of innate immune response [inference]

innate immune response-activating signaling pathway [inference]

pattern recognition receptor signaling pathway [inference]

toll-like receptor signaling pathway

MyD88-dependent toll-like receptor signaling pathway

cytoplasmic pattern recognition receptor signaling pathway [inference]

endolysosomal toll-like receptor signaling pathway [inference]

toll-like receptor 9 signaling pathway

positive regulation of pattern recognition receptor signaling pathway [inference]

positive regulation of toll-like receptor 9 signaling pathway

regulation of innate immune response [inference]

positive regulation of innate immune response [inference]

activation of innate immune response [inference]

innate immune response-activating signaling pathway [inference]

pattern recognition receptor signaling pathway [inference]

toll-like receptor signaling pathway

MyD88-dependent toll-like receptor signaling pathway

cytoplasmic pattern recognition receptor signaling pathway [inference]

endolysosomal toll-like receptor signaling pathway [inference]

toll-like receptor 9 signaling pathway

positive regulation of pattern recognition receptor signaling pathway [inference]

positive regulation of toll-like receptor 9 signaling pathway

regulation of pattern recognition receptor signaling pathway [inference]

regulation of cytoplasmic pattern recognition receptor signaling pathway [inference]

regulation of toll-like receptor 9 signaling pathway [inference]

positive regulation of toll-like receptor 9 signaling pathway

positive regulation of pattern recognition receptor signaling pathway [inference]

positive regulation of toll-like receptor 9 signaling pathway

regulation of signal transduction [inference]

positive regulation of signal transduction [inference]

positive regulation of pattern recognition receptor signaling pathway [inference]

positive regulation of toll-like receptor 9 signaling pathway

positive regulation of intracellular signal transduction [inference]

positive regulation of MAPK cascade

positive regulation of JNK cascade

negative regulation of signal transduction [inference]

negative regulation of intracellular signal transduction [inference]

negative regulation of MAPK cascade [inference]

negative regulation of ERK1 and ERK2 cascade

regulation of pattern recognition receptor signaling pathway [inference]

regulation of cytoplasmic pattern recognition receptor signaling pathway [inference]

regulation of toll-like receptor 9 signaling pathway [inference]

positive regulation of toll-like receptor 9 signaling pathway

positive regulation of pattern recognition receptor signaling pathway [inference]

positive regulation of toll-like receptor 9 signaling pathway

regulation of intracellular signal transduction [inference]

regulation of cytoplasmic pattern recognition receptor signaling pathway [inference]

regulation of toll-like receptor 9 signaling pathway [inference]

positive regulation of toll-like receptor 9 signaling pathway

regulation of canonical NF-kappaB signal transduction [inference]

positive regulation of canonical NF-kappaB signal transduction

regulation of MAPK cascade [inference]

negative regulation of MAPK cascade [inference]

negative regulation of ERK1 and ERK2 cascade

positive regulation of MAPK cascade

positive regulation of JNK cascade

regulation of JNK cascade [inference]

positive regulation of JNK cascade

regulation of ERK1 and ERK2 cascade [inference]

negative regulation of ERK1 and ERK2 cascade

negative regulation of intracellular signal transduction [inference]

negative regulation of MAPK cascade [inference]

negative regulation of ERK1 and ERK2 cascade

positive regulation of intracellular signal transduction [inference]

positive regulation of MAPK cascade

positive regulation of JNK cascade

regulation of response to external stimulus [inference]

positive regulation of response to external stimulus [inference]

positive regulation of innate immune response [inference]

activation of innate immune response [inference]

innate immune response-activating signaling pathway [inference]

pattern recognition receptor signaling pathway [inference]

toll-like receptor signaling pathway

MyD88-dependent toll-like receptor signaling pathway

cytoplasmic pattern recognition receptor signaling pathway [inference]

endolysosomal toll-like receptor signaling pathway [inference]

toll-like receptor 9 signaling pathway

positive regulation of pattern recognition receptor signaling pathway [inference]

positive regulation of toll-like receptor 9 signaling pathway

positive regulation of inflammatory response

regulation of innate immune response [inference]

positive regulation of innate immune response [inference]

activation of innate immune response [inference]

innate immune response-activating signaling pathway [inference]

pattern recognition receptor signaling pathway [inference]

toll-like receptor signaling pathway

MyD88-dependent toll-like receptor signaling pathway

cytoplasmic pattern recognition receptor signaling pathway [inference]

endolysosomal toll-like receptor signaling pathway [inference]

toll-like receptor 9 signaling pathway

positive regulation of pattern recognition receptor signaling pathway [inference]

positive regulation of toll-like receptor 9 signaling pathway

regulation of pattern recognition receptor signaling pathway [inference]

regulation of cytoplasmic pattern recognition receptor signaling pathway [inference]

regulation of toll-like receptor 9 signaling pathway [inference]

positive regulation of toll-like receptor 9 signaling pathway

positive regulation of pattern recognition receptor signaling pathway [inference]

positive regulation of toll-like receptor 9 signaling pathway

regulation of inflammatory response [inference]

positive regulation of inflammatory response

positive regulation of response to stimulus [inference]

positive regulation of response to biotic stimulus [inference]

positive regulation of innate immune response [inference]

activation of innate immune response [inference]

innate immune response-activating signaling pathway [inference]

pattern recognition receptor signaling pathway [inference]

toll-like receptor signaling pathway

MyD88-dependent toll-like receptor signaling pathway

cytoplasmic pattern recognition receptor signaling pathway [inference]

endolysosomal toll-like receptor signaling pathway [inference]

toll-like receptor 9 signaling pathway

positive regulation of pattern recognition receptor signaling pathway [inference]

positive regulation of toll-like receptor 9 signaling pathway

positive regulation of signal transduction [inference]

positive regulation of pattern recognition receptor signaling pathway [inference]

positive regulation of toll-like receptor 9 signaling pathway

positive regulation of intracellular signal transduction [inference]

positive regulation of MAPK cascade

positive regulation of JNK cascade

positive regulation of defense response [inference]

positive regulation of innate immune response [inference]

activation of innate immune response [inference]

innate immune response-activating signaling pathway [inference]

pattern recognition receptor signaling pathway [inference]

toll-like receptor signaling pathway

MyD88-dependent toll-like receptor signaling pathway

cytoplasmic pattern recognition receptor signaling pathway [inference]

endolysosomal toll-like receptor signaling pathway [inference]

toll-like receptor 9 signaling pathway

positive regulation of pattern recognition receptor signaling pathway [inference]

positive regulation of toll-like receptor 9 signaling pathway

positive regulation of inflammatory response

positive regulation of response to external stimulus [inference]

positive regulation of innate immune response [inference]

activation of innate immune response [inference]

innate immune response-activating signaling pathway [inference]

pattern recognition receptor signaling pathway [inference]

toll-like receptor signaling pathway

MyD88-dependent toll-like receptor signaling pathway

cytoplasmic pattern recognition receptor signaling pathway [inference]

endolysosomal toll-like receptor signaling pathway [inference]

toll-like receptor 9 signaling pathway

positive regulation of pattern recognition receptor signaling pathway [inference]

positive regulation of toll-like receptor 9 signaling pathway

positive regulation of inflammatory response

positive regulation of immune response [inference]

activation of immune response [inference]

activation of innate immune response [inference]

innate immune response-activating signaling pathway [inference]

pattern recognition receptor signaling pathway [inference]

toll-like receptor signaling pathway

MyD88-dependent toll-like receptor signaling pathway

cytoplasmic pattern recognition receptor signaling pathway [inference]

endolysosomal toll-like receptor signaling pathway [inference]

toll-like receptor 9 signaling pathway

immune response-activating signaling pathway [inference]

innate immune response-activating signaling pathway [inference]

pattern recognition receptor signaling pathway [inference]

toll-like receptor signaling pathway

MyD88-dependent toll-like receptor signaling pathway

cytoplasmic pattern recognition receptor signaling pathway [inference]

endolysosomal toll-like receptor signaling pathway [inference]

toll-like receptor 9 signaling pathway

positive regulation of innate immune response [inference]

activation of innate immune response [inference]

innate immune response-activating signaling pathway [inference]

pattern recognition receptor signaling pathway [inference]

toll-like receptor signaling pathway

MyD88-dependent toll-like receptor signaling pathway

cytoplasmic pattern recognition receptor signaling pathway [inference]

endolysosomal toll-like receptor signaling pathway [inference]

toll-like receptor 9 signaling pathway

positive regulation of pattern recognition receptor signaling pathway [inference]

positive regulation of toll-like receptor 9 signaling pathway

negative regulation of response to stimulus [inference]

negative regulation of signal transduction [inference]

negative regulation of intracellular signal transduction [inference]

negative regulation of MAPK cascade [inference]

negative regulation of ERK1 and ERK2 cascade

regulation of immune response [inference]

immune response-regulating signaling pathway [inference]

immune response-activating signaling pathway [inference]

innate immune response-activating signaling pathway [inference]

pattern recognition receptor signaling pathway [inference]

toll-like receptor signaling pathway

MyD88-dependent toll-like receptor signaling pathway

cytoplasmic pattern recognition receptor signaling pathway [inference]

endolysosomal toll-like receptor signaling pathway [inference]

toll-like receptor 9 signaling pathway

regulation of innate immune response [inference]

positive regulation of innate immune response [inference]

activation of innate immune response [inference]

innate immune response-activating signaling pathway [inference]

pattern recognition receptor signaling pathway [inference]

toll-like receptor signaling pathway

MyD88-dependent toll-like receptor signaling pathway

cytoplasmic pattern recognition receptor signaling pathway [inference]

endolysosomal toll-like receptor signaling pathway [inference]

toll-like receptor 9 signaling pathway

positive regulation of pattern recognition receptor signaling pathway [inference]

positive regulation of toll-like receptor 9 signaling pathway

regulation of pattern recognition receptor signaling pathway [inference]

regulation of cytoplasmic pattern recognition receptor signaling pathway [inference]

regulation of toll-like receptor 9 signaling pathway [inference]

positive regulation of toll-like receptor 9 signaling pathway

positive regulation of pattern recognition receptor signaling pathway [inference]

positive regulation of toll-like receptor 9 signaling pathway

positive regulation of immune response [inference]

activation of immune response [inference]

activation of innate immune response [inference]

innate immune response-activating signaling pathway [inference]

pattern recognition receptor signaling pathway [inference]

toll-like receptor signaling pathway

MyD88-dependent toll-like receptor signaling pathway

cytoplasmic pattern recognition receptor signaling pathway [inference]

endolysosomal toll-like receptor signaling pathway [inference]

toll-like receptor 9 signaling pathway

immune response-activating signaling pathway [inference]

innate immune response-activating signaling pathway [inference]

pattern recognition receptor signaling pathway [inference]

toll-like receptor signaling pathway

MyD88-dependent toll-like receptor signaling pathway

cytoplasmic pattern recognition receptor signaling pathway [inference]

endolysosomal toll-like receptor signaling pathway [inference]

toll-like receptor 9 signaling pathway

positive regulation of innate immune response [inference]

activation of innate immune response [inference]

innate immune response-activating signaling pathway [inference]

pattern recognition receptor signaling pathway [inference]

toll-like receptor signaling pathway

MyD88-dependent toll-like receptor signaling pathway

cytoplasmic pattern recognition receptor signaling pathway [inference]

endolysosomal toll-like receptor signaling pathway [inference]

toll-like receptor 9 signaling pathway

positive regulation of pattern recognition receptor signaling pathway [inference]

positive regulation of toll-like receptor 9 signaling pathway

regulation of response to stress [inference]

regulation of defense response [inference]

positive regulation of defense response [inference]

positive regulation of innate immune response [inference]

activation of innate immune response [inference]

innate immune response-activating signaling pathway [inference]

pattern recognition receptor signaling pathway [inference]

toll-like receptor signaling pathway

MyD88-dependent toll-like receptor signaling pathway

cytoplasmic pattern recognition receptor signaling pathway [inference]

endolysosomal toll-like receptor signaling pathway [inference]

toll-like receptor 9 signaling pathway

positive regulation of pattern recognition receptor signaling pathway [inference]

positive regulation of toll-like receptor 9 signaling pathway

positive regulation of inflammatory response

regulation of innate immune response [inference]

positive regulation of innate immune response [inference]

activation of innate immune response [inference]

innate immune response-activating signaling pathway [inference]

pattern recognition receptor signaling pathway [inference]

toll-like receptor signaling pathway

MyD88-dependent toll-like receptor signaling pathway

cytoplasmic pattern recognition receptor signaling pathway [inference]

endolysosomal toll-like receptor signaling pathway [inference]

toll-like receptor 9 signaling pathway

positive regulation of pattern recognition receptor signaling pathway [inference]

positive regulation of toll-like receptor 9 signaling pathway

regulation of pattern recognition receptor signaling pathway [inference]

regulation of cytoplasmic pattern recognition receptor signaling pathway [inference]

regulation of toll-like receptor 9 signaling pathway [inference]

positive regulation of toll-like receptor 9 signaling pathway

positive regulation of pattern recognition receptor signaling pathway [inference]

positive regulation of toll-like receptor 9 signaling pathway

regulation of inflammatory response [inference]

positive regulation of inflammatory response

regulation of developmental process [inference]

regulation of cell differentiation [inference]

regulation of epithelial cell differentiation [inference]

regulation of intestinal epithelial cell development [inference]

positive regulation of intestinal epithelial cell development

positive regulation of cell differentiation [inference]

positive regulation of cell development [inference]

positive regulation of intestinal epithelial cell development

regulation of cell development [inference]

positive regulation of cell development [inference]

positive regulation of intestinal epithelial cell development

regulation of hemopoiesis [inference]

regulation of leukocyte differentiation [inference]

regulation of lymphocyte differentiation [inference]

regulation of B cell differentiation

regulation of intestinal epithelial cell development [inference]

positive regulation of intestinal epithelial cell development

positive regulation of developmental process [inference]

positive regulation of cell differentiation [inference]

positive regulation of cell development [inference]

positive regulation of intestinal epithelial cell development

regulation of multicellular organismal development [inference]

regulation of epithelial cell differentiation [inference]

regulation of intestinal epithelial cell development [inference]

positive regulation of intestinal epithelial cell development

regulation of hemopoiesis [inference]

regulation of leukocyte differentiation [inference]

regulation of lymphocyte differentiation [inference]

regulation of B cell differentiation

regulation of cellular process [inference]

signal transduction [inference]

immune response-regulating signaling pathway [inference]

immune response-activating signaling pathway [inference]

innate immune response-activating signaling pathway [inference]

pattern recognition receptor signaling pathway [inference]

toll-like receptor signaling pathway

MyD88-dependent toll-like receptor signaling pathway

cytoplasmic pattern recognition receptor signaling pathway [inference]

endolysosomal toll-like receptor signaling pathway [inference]

toll-like receptor 9 signaling pathway

intracellular signal transduction [inference]

intracellular receptor signaling pathway [inference]

cytoplasmic pattern recognition receptor signaling pathway [inference]

endolysosomal toll-like receptor signaling pathway [inference]

toll-like receptor 9 signaling pathway

intracellular signaling cassette [inference]

canonical NF-kappaB signal transduction

regulation of cell communication [inference]

regulation of signal transduction [inference]

positive regulation of signal transduction [inference]

positive regulation of pattern recognition receptor signaling pathway [inference]

positive regulation of toll-like receptor 9 signaling pathway

positive regulation of intracellular signal transduction [inference]

positive regulation of MAPK cascade

positive regulation of JNK cascade

negative regulation of signal transduction [inference]

negative regulation of intracellular signal transduction [inference]

negative regulation of MAPK cascade [inference]

negative regulation of ERK1 and ERK2 cascade

regulation of pattern recognition receptor signaling pathway [inference]

regulation of cytoplasmic pattern recognition receptor signaling pathway [inference]

regulation of toll-like receptor 9 signaling pathway [inference]

positive regulation of toll-like receptor 9 signaling pathway

positive regulation of pattern recognition receptor signaling pathway [inference]

positive regulation of toll-like receptor 9 signaling pathway

regulation of intracellular signal transduction [inference]

regulation of cytoplasmic pattern recognition receptor signaling pathway [inference]

regulation of toll-like receptor 9 signaling pathway [inference]

positive regulation of toll-like receptor 9 signaling pathway

regulation of canonical NF-kappaB signal transduction [inference]

positive regulation of canonical NF-kappaB signal transduction

regulation of MAPK cascade [inference]

negative regulation of MAPK cascade [inference]

negative regulation of ERK1 and ERK2 cascade

positive regulation of MAPK cascade

positive regulation of JNK cascade

regulation of JNK cascade [inference]

positive regulation of JNK cascade

regulation of ERK1 and ERK2 cascade [inference]

negative regulation of ERK1 and ERK2 cascade

negative regulation of intracellular signal transduction [inference]

negative regulation of MAPK cascade [inference]

negative regulation of ERK1 and ERK2 cascade

positive regulation of intracellular signal transduction [inference]

positive regulation of MAPK cascade

positive regulation of JNK cascade

positive regulation of cell communication [inference]

positive regulation of signal transduction [inference]

positive regulation of pattern recognition receptor signaling pathway [inference]

positive regulation of toll-like receptor 9 signaling pathway

positive regulation of intracellular signal transduction [inference]

positive regulation of MAPK cascade

positive regulation of JNK cascade

negative regulation of cell communication [inference]

negative regulation of signal transduction [inference]

negative regulation of intracellular signal transduction [inference]

negative regulation of MAPK cascade [inference]

negative regulation of ERK1 and ERK2 cascade

regulation of metabolic process [inference]

regulation of biosynthetic process [inference]

positive regulation of biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

positive regulation of cytokine production [inference]

positive regulation of type I interferon production [inference]

positive regulation of tumor necrosis factor superfamily cytokine production [inference]

positive regulation of tumor necrosis factor production

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of immunoglobulin production

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of cytokine production [inference]

positive regulation of cytokine production [inference]

positive regulation of type I interferon production [inference]

positive regulation of tumor necrosis factor superfamily cytokine production [inference]

positive regulation of tumor necrosis factor production

regulation of cytokine production involved in immune response [inference]

regulation of dendritic cell cytokine production

regulation of type I interferon production [inference]

positive regulation of type I interferon production [inference]

regulation of interferon-alpha production [inference]

positive regulation of interferon-alpha production

regulation of interferon-beta production [inference]

positive regulation of interferon-beta production

regulation of chemokine production [inference]

positive regulation of chemokine production

regulation of granulocyte macrophage colony-stimulating factor production [inference]

positive regulation of granulocyte macrophage colony-stimulating factor production

regulation of type II interferon production [inference]

positive regulation of type II interferon production

regulation of interleukin-10 production [inference]

positive regulation of interleukin-10 production

regulation of interleukin-12 production [inference]

positive regulation of interleukin-12 production

regulation of interleukin-18 production [inference]

positive regulation of interleukin-18 production

regulation of interleukin-6 production [inference]

positive regulation of interleukin-6 production

regulation of interleukin-8 production [inference]

positive regulation of interleukin-8 production

regulation of tumor necrosis factor superfamily cytokine production [inference]

regulation of tumor necrosis factor production [inference]

positive regulation of tumor necrosis factor production

positive regulation of tumor necrosis factor superfamily cytokine production [inference]

positive regulation of tumor necrosis factor production

regulation of production of molecular mediator of immune response [inference]

regulation of immunoglobulin production [inference]

positive regulation of immunoglobulin production

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of immunoglobulin production

regulation of cytokine production involved in immune response [inference]

regulation of dendritic cell cytokine production

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase II [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of gene expression

positive regulation of cytokine production [inference]

positive regulation of type I interferon production [inference]

positive regulation of tumor necrosis factor superfamily cytokine production [inference]

positive regulation of tumor necrosis factor production

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of immunoglobulin production

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

positive regulation of cytokine production [inference]

positive regulation of type I interferon production [inference]

positive regulation of tumor necrosis factor superfamily cytokine production [inference]

positive regulation of tumor necrosis factor production

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of immunoglobulin production

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase II [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of metabolic process [inference]

positive regulation of biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

positive regulation of cytokine production [inference]

positive regulation of type I interferon production [inference]

positive regulation of tumor necrosis factor superfamily cytokine production [inference]

positive regulation of tumor necrosis factor production

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of immunoglobulin production

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of catabolic process [inference]

positive regulation of autophagy

positive regulation of macromolecule metabolic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

positive regulation of cytokine production [inference]

positive regulation of type I interferon production [inference]

positive regulation of tumor necrosis factor superfamily cytokine production [inference]

positive regulation of tumor necrosis factor production

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of immunoglobulin production

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of protein metabolic process [inference]

positive regulation of granulocyte macrophage colony-stimulating factor production

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

regulation of catabolic process [inference]

positive regulation of catabolic process [inference]

positive regulation of autophagy

regulation of autophagy [inference]

positive regulation of autophagy

regulation of macromolecule metabolic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of cytokine production [inference]

positive regulation of cytokine production [inference]

positive regulation of type I interferon production [inference]

positive regulation of tumor necrosis factor superfamily cytokine production [inference]

positive regulation of tumor necrosis factor production

regulation of cytokine production involved in immune response [inference]

regulation of dendritic cell cytokine production

regulation of type I interferon production [inference]

positive regulation of type I interferon production [inference]

regulation of interferon-alpha production [inference]

positive regulation of interferon-alpha production

regulation of interferon-beta production [inference]

positive regulation of interferon-beta production

regulation of chemokine production [inference]

positive regulation of chemokine production

regulation of granulocyte macrophage colony-stimulating factor production [inference]

positive regulation of granulocyte macrophage colony-stimulating factor production

regulation of type II interferon production [inference]

positive regulation of type II interferon production

regulation of interleukin-10 production [inference]

positive regulation of interleukin-10 production

regulation of interleukin-12 production [inference]

positive regulation of interleukin-12 production

regulation of interleukin-18 production [inference]

positive regulation of interleukin-18 production

regulation of interleukin-6 production [inference]

positive regulation of interleukin-6 production

regulation of interleukin-8 production [inference]

positive regulation of interleukin-8 production

regulation of tumor necrosis factor superfamily cytokine production [inference]

regulation of tumor necrosis factor production [inference]

positive regulation of tumor necrosis factor production

positive regulation of tumor necrosis factor superfamily cytokine production [inference]

positive regulation of tumor necrosis factor production

regulation of production of molecular mediator of immune response [inference]

regulation of immunoglobulin production [inference]

positive regulation of immunoglobulin production

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of immunoglobulin production

regulation of cytokine production involved in immune response [inference]

regulation of dendritic cell cytokine production

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase II [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of gene expression

positive regulation of cytokine production [inference]

positive regulation of type I interferon production [inference]

positive regulation of tumor necrosis factor superfamily cytokine production [inference]

positive regulation of tumor necrosis factor production

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of immunoglobulin production

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

positive regulation of cytokine production [inference]

positive regulation of type I interferon production [inference]

positive regulation of tumor necrosis factor superfamily cytokine production [inference]

positive regulation of tumor necrosis factor production

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of immunoglobulin production

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase II [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of macromolecule metabolic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

positive regulation of cytokine production [inference]

positive regulation of type I interferon production [inference]

positive regulation of tumor necrosis factor superfamily cytokine production [inference]

positive regulation of tumor necrosis factor production

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of immunoglobulin production

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of protein metabolic process [inference]

positive regulation of granulocyte macrophage colony-stimulating factor production

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

regulation of protein metabolic process [inference]

regulation of granulocyte macrophage colony-stimulating factor production [inference]

positive regulation of granulocyte macrophage colony-stimulating factor production

positive regulation of protein metabolic process [inference]

positive regulation of granulocyte macrophage colony-stimulating factor production

regulation of RNA metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase II [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

regulation of primary metabolic process [inference]

regulation of nucleobase-containing compound metabolic process [inference]

regulation of RNA metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase II [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

regulation of protein metabolic process [inference]

regulation of granulocyte macrophage colony-stimulating factor production [inference]

positive regulation of granulocyte macrophage colony-stimulating factor production

positive regulation of protein metabolic process [inference]

positive regulation of granulocyte macrophage colony-stimulating factor production

regulation of transmembrane transport [inference]

regulation of transmembrane transporter activity [inference]

negative regulation of ion transmembrane transporter activity [inference]

negative regulation of calcium ion transmembrane transporter activity [inference]

negative regulation of ATPase-coupled calcium transmembrane transporter activity

regulation of ATPase-coupled calcium transmembrane transporter activity [inference]

negative regulation of ATPase-coupled calcium transmembrane transporter activity

negative regulation of transmembrane transport [inference]

negative regulation of monoatomic ion transmembrane transport [inference]

negative regulation of ion transmembrane transporter activity [inference]

negative regulation of calcium ion transmembrane transporter activity [inference]

negative regulation of ATPase-coupled calcium transmembrane transporter activity

negative regulation of cation transmembrane transport [inference]

negative regulation of calcium ion transmembrane transport [inference]

negative regulation of calcium ion transmembrane transporter activity [inference]

negative regulation of ATPase-coupled calcium transmembrane transporter activity

regulation of monoatomic ion transmembrane transport [inference]

negative regulation of monoatomic ion transmembrane transport [inference]

negative regulation of ion transmembrane transporter activity [inference]

negative regulation of calcium ion transmembrane transporter activity [inference]

negative regulation of ATPase-coupled calcium transmembrane transporter activity

negative regulation of cation transmembrane transport [inference]

negative regulation of calcium ion transmembrane transport [inference]

negative regulation of calcium ion transmembrane transporter activity [inference]

negative regulation of ATPase-coupled calcium transmembrane transporter activity

regulation of monoatomic cation transmembrane transport [inference]

regulation of calcium ion transmembrane transport [inference]

negative regulation of calcium ion transmembrane transport [inference]

negative regulation of calcium ion transmembrane transporter activity [inference]

negative regulation of ATPase-coupled calcium transmembrane transporter activity

negative regulation of cation transmembrane transport [inference]

negative regulation of calcium ion transmembrane transport [inference]

negative regulation of calcium ion transmembrane transporter activity [inference]

negative regulation of ATPase-coupled calcium transmembrane transporter activity

regulation of cell population proliferation [inference]

positive regulation of cell population proliferation [inference]

positive regulation of leukocyte proliferation [inference]

positive regulation of mononuclear cell proliferation [inference]

positive regulation of lymphocyte proliferation [inference]

positive regulation of B cell proliferation

regulation of leukocyte proliferation [inference]

regulation of mononuclear cell proliferation [inference]

positive regulation of mononuclear cell proliferation [inference]

positive regulation of lymphocyte proliferation [inference]

positive regulation of B cell proliferation

regulation of lymphocyte proliferation [inference]

regulation of B cell proliferation [inference]

positive regulation of B cell proliferation

positive regulation of lymphocyte proliferation [inference]

positive regulation of B cell proliferation

positive regulation of leukocyte proliferation [inference]

positive regulation of mononuclear cell proliferation [inference]

positive regulation of lymphocyte proliferation [inference]

positive regulation of B cell proliferation

regulation of cell differentiation [inference]

regulation of epithelial cell differentiation [inference]

regulation of intestinal epithelial cell development [inference]

positive regulation of intestinal epithelial cell development

positive regulation of cell differentiation [inference]

positive regulation of cell development [inference]

positive regulation of intestinal epithelial cell development

regulation of cell development [inference]

positive regulation of cell development [inference]

positive regulation of intestinal epithelial cell development

regulation of hemopoiesis [inference]

regulation of leukocyte differentiation [inference]

regulation of lymphocyte differentiation [inference]

regulation of B cell differentiation

regulation of intestinal epithelial cell development [inference]

positive regulation of intestinal epithelial cell development

positive regulation of cellular process [inference]

positive regulation of cell population proliferation [inference]

positive regulation of leukocyte proliferation [inference]

positive regulation of mononuclear cell proliferation [inference]

positive regulation of lymphocyte proliferation [inference]

positive regulation of B cell proliferation

positive regulation of metabolic process [inference]

positive regulation of biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

positive regulation of cytokine production [inference]

positive regulation of type I interferon production [inference]

positive regulation of tumor necrosis factor superfamily cytokine production [inference]

positive regulation of tumor necrosis factor production

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of immunoglobulin production

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of catabolic process [inference]

positive regulation of autophagy

positive regulation of macromolecule metabolic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

positive regulation of cytokine production [inference]

positive regulation of type I interferon production [inference]

positive regulation of tumor necrosis factor superfamily cytokine production [inference]

positive regulation of tumor necrosis factor production

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of immunoglobulin production

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of protein metabolic process [inference]

positive regulation of granulocyte macrophage colony-stimulating factor production

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of cell communication [inference]

positive regulation of signal transduction [inference]

positive regulation of pattern recognition receptor signaling pathway [inference]

positive regulation of toll-like receptor 9 signaling pathway

positive regulation of intracellular signal transduction [inference]

positive regulation of MAPK cascade

positive regulation of JNK cascade

positive regulation of cell differentiation [inference]

positive regulation of cell development [inference]

positive regulation of intestinal epithelial cell development

positive regulation of cell activation [inference]

positive regulation of leukocyte activation [inference]

positive regulation of lymphocyte activation [inference]

positive regulation of lymphocyte proliferation [inference]

positive regulation of B cell proliferation

positive regulation of B cell activation

positive regulation of B cell proliferation

negative regulation of cellular process [inference]

negative regulation of cell communication [inference]

negative regulation of signal transduction [inference]

negative regulation of intracellular signal transduction [inference]

negative regulation of MAPK cascade [inference]

negative regulation of ERK1 and ERK2 cascade

negative regulation of transmembrane transport [inference]

negative regulation of monoatomic ion transmembrane transport [inference]

negative regulation of ion transmembrane transporter activity [inference]

negative regulation of calcium ion transmembrane transporter activity [inference]

negative regulation of ATPase-coupled calcium transmembrane transporter activity

negative regulation of cation transmembrane transport [inference]

negative regulation of calcium ion transmembrane transport [inference]

negative regulation of calcium ion transmembrane transporter activity [inference]

negative regulation of ATPase-coupled calcium transmembrane transporter activity

regulation of cell activation [inference]

regulation of leukocyte activation [inference]

positive regulation of leukocyte activation [inference]

positive regulation of lymphocyte activation [inference]

positive regulation of lymphocyte proliferation [inference]

positive regulation of B cell proliferation

positive regulation of B cell activation

positive regulation of B cell proliferation

regulation of lymphocyte activation [inference]

regulation of lymphocyte differentiation [inference]

regulation of B cell differentiation

regulation of lymphocyte proliferation [inference]

regulation of B cell proliferation [inference]

positive regulation of B cell proliferation

positive regulation of lymphocyte proliferation [inference]

positive regulation of B cell proliferation

regulation of B cell activation [inference]

regulation of B cell proliferation [inference]

positive regulation of B cell proliferation

regulation of B cell differentiation

positive regulation of B cell activation

positive regulation of B cell proliferation

positive regulation of lymphocyte activation [inference]

positive regulation of lymphocyte proliferation [inference]

positive regulation of B cell proliferation

positive regulation of B cell activation

positive regulation of B cell proliferation

positive regulation of cell activation [inference]

positive regulation of leukocyte activation [inference]

positive regulation of lymphocyte activation [inference]

positive regulation of lymphocyte proliferation [inference]

positive regulation of B cell proliferation

positive regulation of B cell activation

positive regulation of B cell proliferation

regulation of multicellular organismal process [inference]

regulation of cytokine production [inference]

positive regulation of cytokine production [inference]

positive regulation of type I interferon production [inference]

positive regulation of tumor necrosis factor superfamily cytokine production [inference]

positive regulation of tumor necrosis factor production

regulation of cytokine production involved in immune response [inference]

regulation of dendritic cell cytokine production

regulation of type I interferon production [inference]

positive regulation of type I interferon production [inference]

regulation of interferon-alpha production [inference]

positive regulation of interferon-alpha production

regulation of interferon-beta production [inference]

positive regulation of interferon-beta production

regulation of chemokine production [inference]

positive regulation of chemokine production

regulation of granulocyte macrophage colony-stimulating factor production [inference]

positive regulation of granulocyte macrophage colony-stimulating factor production

regulation of type II interferon production [inference]

positive regulation of type II interferon production

regulation of interleukin-10 production [inference]

positive regulation of interleukin-10 production

regulation of interleukin-12 production [inference]

positive regulation of interleukin-12 production

regulation of interleukin-18 production [inference]

positive regulation of interleukin-18 production

regulation of interleukin-6 production [inference]

positive regulation of interleukin-6 production

regulation of interleukin-8 production [inference]

positive regulation of interleukin-8 production

regulation of tumor necrosis factor superfamily cytokine production [inference]

regulation of tumor necrosis factor production [inference]

positive regulation of tumor necrosis factor production

positive regulation of tumor necrosis factor superfamily cytokine production [inference]

positive regulation of tumor necrosis factor production

regulation of cell activation [inference]

regulation of leukocyte activation [inference]

positive regulation of leukocyte activation [inference]

positive regulation of lymphocyte activation [inference]

positive regulation of lymphocyte proliferation [inference]

positive regulation of B cell proliferation

positive regulation of B cell activation

positive regulation of B cell proliferation

regulation of lymphocyte activation [inference]

regulation of lymphocyte differentiation [inference]

regulation of B cell differentiation

regulation of lymphocyte proliferation [inference]

regulation of B cell proliferation [inference]

positive regulation of B cell proliferation

positive regulation of lymphocyte proliferation [inference]

positive regulation of B cell proliferation

regulation of B cell activation [inference]

regulation of B cell proliferation [inference]

positive regulation of B cell proliferation

regulation of B cell differentiation

positive regulation of B cell activation

positive regulation of B cell proliferation

positive regulation of lymphocyte activation [inference]

positive regulation of lymphocyte proliferation [inference]

positive regulation of B cell proliferation

positive regulation of B cell activation

positive regulation of B cell proliferation

positive regulation of cell activation [inference]

positive regulation of leukocyte activation [inference]

positive regulation of lymphocyte activation [inference]

positive regulation of lymphocyte proliferation [inference]

positive regulation of B cell proliferation

positive regulation of B cell activation

positive regulation of B cell proliferation

positive regulation of multicellular organismal process [inference]

positive regulation of cytokine production [inference]

positive regulation of type I interferon production [inference]

positive regulation of tumor necrosis factor superfamily cytokine production [inference]

positive regulation of tumor necrosis factor production

positive regulation of cell activation [inference]

positive regulation of leukocyte activation [inference]

positive regulation of lymphocyte activation [inference]

positive regulation of lymphocyte proliferation [inference]

positive regulation of B cell proliferation

positive regulation of B cell activation

positive regulation of B cell proliferation

positive regulation of intestinal epithelial cell development

regulation of multicellular organismal development [inference]

regulation of epithelial cell differentiation [inference]

regulation of intestinal epithelial cell development [inference]

positive regulation of intestinal epithelial cell development

regulation of hemopoiesis [inference]

regulation of leukocyte differentiation [inference]

regulation of lymphocyte differentiation [inference]

regulation of B cell differentiation

regulation of molecular function [inference]

regulation of transmembrane transporter activity [inference]

negative regulation of ion transmembrane transporter activity [inference]

negative regulation of calcium ion transmembrane transporter activity [inference]

negative regulation of ATPase-coupled calcium transmembrane transporter activity

regulation of ATPase-coupled calcium transmembrane transporter activity [inference]

negative regulation of ATPase-coupled calcium transmembrane transporter activity

regulation of ATP-dependent activity [inference]

negative regulation of ATP-dependent activity [inference]

negative regulation of ATPase-coupled calcium transmembrane transporter activity

regulation of ATPase-coupled calcium transmembrane transporter activity [inference]

negative regulation of ATPase-coupled calcium transmembrane transporter activity

negative regulation of molecular function [inference]

negative regulation of transporter activity [inference]

negative regulation of ion transmembrane transporter activity [inference]

negative regulation of calcium ion transmembrane transporter activity [inference]

negative regulation of ATPase-coupled calcium transmembrane transporter activity

negative regulation of ATP-dependent activity [inference]

negative regulation of ATPase-coupled calcium transmembrane transporter activity

Displaying entries **1 - 5** of 29 in total

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GO Term	Evidence Code	Reference
Golgi membrane	EXP	PMID
Golgi membrane	TAS	Reactome Reactome
Golgi membrane	IEA	GO_REF
extracellular region	NAS	PMID
cytoplasm	IDA	PMID

GO Hierarchy

cellular component

cellular anatomical structure [inference]

membrane [inference]

plasma membrane

organelle membrane [inference]

endoplasmic reticulum membrane

vesicle membrane [inference]

cytoplasmic vesicle membrane [inference]

endosome membrane

bounding membrane of organelle [inference]

Golgi membrane

vacuolar membrane [inference]

lytic vacuole membrane [inference]

lysosomal membrane [inference]

endolysosome membrane

endosome membrane

plasma membrane region [inference]

organelle [inference]

membrane-bounded organelle [inference]

vesicle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

endosome

endolysosome

endocytic vesicle [inference]

phagocytic vesicle [inference]

early phagosome

intracellular membrane-bounded organelle [inference]

vacuole [inference]

lytic vacuole [inference]

lysosome

endolysosome

endoplasmic reticulum

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

endosome

endolysosome

endocytic vesicle [inference]

phagocytic vesicle [inference]

early phagosome

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

vacuole [inference]

lytic vacuole [inference]

lysosome

endolysosome

endoplasmic reticulum

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

endosome

endolysosome

endocytic vesicle [inference]

phagocytic vesicle [inference]

early phagosome

Displaying entries **1 - 5** of 7 in total

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GO Term	Evidence Code	Reference
interleukin-1 receptor binding	IPI	PMID
siRNA binding	IMP	PMID
pattern recognition receptor activity	IDA	PMID PMID
pattern recognition receptor activity	IBA	GO_REF
protein homodimerization activity	ISS	GO_REF

GO Hierarchy

molecular function

binding [inference]

nucleic acid binding [inference]

DNA binding [inference]

sequence-specific DNA binding [inference]

unmethylated CpG binding

RNA binding [inference]

regulatory RNA binding [inference]

siRNA binding

protein binding [inference]

signaling receptor binding [inference]

cytokine receptor binding [inference]

interleukin-1 receptor binding

growth factor receptor binding [inference]

interleukin-1 receptor binding

identical protein binding [inference]

protein homodimerization activity

protein dimerization activity [inference]

protein homodimerization activity

molecular transducer activity [inference]

signaling receptor activity [inference]

pattern recognition receptor activity

Gene Ontology information from UniProt.

Annotation information from UniProt.

Sequence

MGFCRSALHPLSLLVQAIMLAMTLALGTLPAFLPCELQPHGLVNCNWLFLKSVPHFSMAAPRGNVTSLSLSSNRIHHLHDSDFAHLPSLRHLNLKWNCPPVGLSPMHFPCHMTIEPSTFLAVPTLEELNLSYNNIMTVPALPKSLISLSLSHTNILMLDSASLAGLHALRFLFMDGNCYYKNPCRQALEVAPGALLGLGNLTHLSLKYNNLTVVPRNLPSSLEYLLLSYNRIVKLAPEDLANLTALRVLDVGGNCRRCDHAPNPCMECPRHFPQLHPDTFSHLSRLEGLVLKDSSLSWLNASWFRGLGNLRVLDLSENFLYKCITKTKAFQGLTQLRKLNLSFNYQKRVSFAHLSLAPSFGSLVALKELDMHGIFFRSLDETTLRPLARLPMLQTLRLQMNFINQAQLGIFRAFPGLRYVDLSDNRISGASELTATMGEADGGEKVWLQPGDLAPAPVDTPSSEDFRPNCSTLNFTLDLSRNNLVTVQPEMFAQLSHLQCLRLSHNCISQAVNGSQFLPLTGLQVLDLSHNKLDLYHEHSFTELPRLEALDLSYNSQPFGMQGVGHNFSFVAHLRTLRHLSLAHNNIHSQVSQQLCSTSLRALDFSGNALGHMWAEGDLYLHFFQGLSGLIWLDLSQNRLHTLLPQTLRNLPKSLQVLRLRDNYLAFFKWWSLHFLPKLEVLDLAGNQLKALTNGSLPAGTRLRRLDVSCNSISFVAPGFFSKAKELRELNLSANALKTVDHSWFGPLASALQILDVSANPLHCACGAAFMDFLLEVQAAVPGLPSRVKCGSPGQLQGLSIFAQDLRLCLDEALSWDCFALSLLAVALGLGVPMLHHLCGWDLWYCFHLCLAWLPWRGRQSGRDEDALPYDAFVVFDKTQSAVADWVYNELRGQLEECRGRWALRLCLEERDWLPGKTLFENLWASVYGSRKTLFVLAHTDRVSGLLRASFLLAQQRLLEDRKDVVVLVILSPDGRRSRYVRLRQRLCRQSVLLWPHQPSGQRSFWAQLGMALTRDNHHFYNRNFCQGPTAE

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying entries **1 - 10** of 14 in total

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Position	Description	PubMed ID	GlyTouCan ID	Source
64	N-linked (GlcNAc...) asparagine	24190977 37074911	G80920RR G62765YT G31852PQ	UniProt GlyGen
129	N-linked (GlcNAc...) asparagine			UniProt GlyGen
200	N-linked (GlcNAc...) asparagine	24190977		UniProt GlyGen
209		24190977		GlyGen
210	N-linked (GlcNAc...) asparagine	24190977 37074911	G83460ZZ G80920RR	UniProt GlyGen
242	N-linked (GlcNAc...) asparagine	24190977 37074911	G80920RR	UniProt GlyGen
300	N-linked (GlcNAc...) asparagine	24190977		UniProt GlyGen
340	N-linked (GlcNAc...) asparagine	24190977		UniProt GlyGen
469	N-linked (GlcNAc...) asparagine			UniProt GlyGen
474	N-linked (GlcNAc...) asparagine			UniProt GlyGen

Feature

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

Pathway

Displaying **all 7** entries
Pathway Name	Organism
MyD88 dependent cascade initiated on endosome	Homo sapiens
PI3K Cascade	Homo sapiens
Potential therapeutics for SARS	Homo sapiens
TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling	Homo sapiens
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation	Homo sapiens
Toll Like Receptor 9 (TLR9) Cascade	Homo sapiens
Trafficking and processing of endosomal TLR	Homo sapiens

Disease

Displaying entries **1 - 10** of 15 in total

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DO ID	Disease Name	Source
DOID:2043	hepatitis B	Alliance of Genome Resources
DOID:0080162	lupus nephritis	Alliance of Genome Resources
DOID:784	chronic kidney disease	Alliance of Genome Resources
DOID:1485	cystic fibrosis	Alliance of Genome Resources
DOID:9074	systemic lupus erythematosus	Alliance of Genome Resources
DOID:2841	asthma	Alliance of Genome Resources
DOID:576	proteinuria	Alliance of Genome Resources
DOID:684	hepatocellular carcinoma	Alliance of Genome Resources
DOID:13166	allergic bronchopulmonary aspergillosis	Alliance of Genome Resources
DOID:1287	cardiovascular system disease	Alliance of Genome Resources

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

All Resources

Other Information

Tools

Search Tools

Guidelines

Summary

External Links

Annotation

International Collaboration

Acknowledgements