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MIRAGE
Voltage-dependent calcium channel subunit alpha-2/delta-2
Summary
- UniProt ID
- Q9NY47
- Gene Symbol
-
- CACNA2D2
- KIAA0558
- Gene ID
- 9254
- Organism
- Homo sapiens (human)
External Links
- GlyGen
- Q9NY47
- PubChem
- Q9NY47
- The Human Metabolome Database
- HMDBP07485
- Re-Glyco
- Q9NY47
Annotation
- Keyword
-
- Alternative splicing
- Calcium channel
- Disease variant
- Disulfide bond
- Epilepsy
- Glycoprotein
- Metal-binding
- Reference proteome
- Signal
- Transmembrane helix
- Voltage-gated channel
- Gene Ontology (GO)
| GO Term |
|---|
| voltage-gated calcium channel complex |
| presynaptic active zone membrane |
| GABA-ergic synapse |
| plasma membrane |
| GO Term |
|---|
| metal ion binding |
| voltage-gated calcium channel activity |
Sequence
MAVPARTCGASRPGPARTARPWPGCGPHPGPGTRRPTSGPPRPLWLLLPLLPLLAAPGASAYSFPQQHTMQHWARRLEQEVDGVMRIFGGVQQLREIYKDNRNLFEVQENEPQKLVEKVAGDIESLLDRKVQALKRLADAAENFQKAHRWQDNIKEEDIVYYDAKADAELDDPESEDVERGSKASTLRLDFIEDPNFKNKVNYSYAAVQIPTDIYKGSTVILNELNWTEALENVFMENRRQDPTLLWQVFGSATGVTRYYPATPWRAPKKIDLYDVRRRPWYIQGASSPKDMVIIVDVSGSVSGLTLKLMKTSVCEMLDTLSDDDYVNVASFNEKAQPVSCFTHLVQANVRNKKVFKEAVQGMVAKGTTGYKAGFEYAFDQLQNSNITRANCNKMIMMFTDGGEDRVQDVFEKYNWPNRTVRVFTFSVGQHNYDVTPLQWMACANKGYYFEIPSIGAIRINTQEYLDVLGRPMVLAGKEAKQVQWTNVYEDALGLGLVVTGTLPVFNLTQDGPGEKKNQLILGVMGIDVALNDIKRLTPNYTLGANGYVFAIDLNGYVLLHPNLKPQTTNFREPVTLDFLDAELEDENKEEIRRSMIDGNKGHKQIRTLVKSLDERYIDEVTRNYTWVPIRSTNYSLGLVLPPYSTFYLQANLSDQILQVKLPISKLKDFEFLLPSSFESEGHVFIAPREYCKDLNASDNNTEFLKNFIELMEKVTPDSKQCNNFLLHNLILDTGITQQLVERVWRDQDLNTYSLLAVFAATDGGITRVFPNKAAEDWTENPEPFNASFYRRSLDNHGYVFKPPHQDALLRPLELENDTVGILVSTAVELSLGRRTLRPAVVGVKLDLEAWAEKFKVLASNRTHQDQPQKCGPNSHCEMDCEVNNEDLLCVLIDDGGFLVLSNQNHQWDQVGRFFSEVDANLMLALYNNSFYTRKESYDYQAACAPQPPGNLGAAPRGVFVPTVADFLNLAWWTSAAAWSLFQQLLYGLIYHSWFQADPAEAEGSPETRESSCVMKQTQYYFGSVNASYNAIIDCGNCSRLFHAQRLTNTNLLFVVAEKPLCSQCEAGRLLQKETHSDGPEQCELVQRPRYRRGPHICFDYNATEDTSDCGRGASFPPSLGVLVSLQLLLLLGLPPRPQPQVLVHASRRL
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 202 |
|
|||
| 386 | N-linked (GlcNAc...) asparagine | |||
| 418 | N-linked (GlcNAc...) asparagine |
|
||
| 507 | N-linked (GlcNAc...) asparagine |
|
||
| 540 | N-linked (GlcNAc...) asparagine |
|
||
| 624 | N-linked (GlcNAc...) asparagine | |||
| 696 |
|
|||
| 700 |
|
|||
| 786 |
|
|||
| 861 | N-linked (GlcNAc...) asparagine |
|
G62765YT
G72787SB
G80920RR
G26436YP
G83460ZZ
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Adrenaline,noradrenaline inhibits insulin secretion | Homo sapiens |
| Phase 0 - rapid depolarisation | Homo sapiens |
| Phase 2 - plateau phase | Homo sapiens |
| Presynaptic depolarization and calcium channel opening | Homo sapiens |
| Regulation of insulin secretion | Homo sapiens |
| Sensory processing of sound by inner hair cells of the cochlea | Homo sapiens |
