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Vitamin K-dependent protein C
Summary
- UniProt ID
- P04070
- Gene Symbol
-
- PROC
- Organism
- Homo sapiens (human)
External Links
- GlycoProtDB
- GPDB0011352
- GlyConnect
- GlyGen
- P04070
- PubChem
- P04070
- The Human Metabolome Database
- HMDBP02002
Annotation
- Keyword
-
- 3D-structure
- Alternative splicing
- Calcium
- Cleavage on pair of basic residues
- Direct protein sequencing
- Disease variant
- Disulfide bond
- EGF-like domain
- Endoplasmic reticulum
- Gamma-carboxyglutamic acid
- Glycoprotein
- Golgi apparatus
- Hydroxylation
- Phosphoprotein
- Reference proteome
- Repeat
- Secreted
- Serine protease
- Signal
- Thrombophilia
- Zymogen
- Gene Ontology (GO)
| GO Term |
|---|
| endoplasmic reticulum |
| endoplasmic reticulum lumen |
| Golgi lumen |
| extracellular region |
| extracellular space |
| Golgi apparatus |
| GO Term |
|---|
| calcium ion binding |
| serine-type endopeptidase activity |
Sequence
MWQLTSLLLFVATWGISGTPAPLDSVFSSSERAHQVLRIRKRANSFLEELRHSSLERECIEEICDFEEAKEIFQNVDDTLAFWSKHVDGDQCLVLPLEHPCASLCCGHGTCIDGIGSFSCDCRSGWEGRFCQREVSFLNCSLDNGGCTHYCLEEVGWRRCSCAPGYKLGDDLLQCHPAVKFPCGRPWKRMEKKRSHLKRDTEDQEDQVDPRLIDGKMTRRGDSPWQVVLLDSKKKLACGAVLIHPSWVLTAAHCMDESKKLLVRLGEYDLRRWEKWELDLDIKEVFVHPNYSKSTTDNDIALLHLAQPATLSQTIVPICLPDSGLAERELNQAGQETLVTGWGYHSSREKEAKRNRTFVLNFIKIPVVPHNECSEVMSNMVSENMLCAGILGDRQDACEGDSGGPMVASFHGTWFLVGLVSWGEGCGLLHNYGVYTKVSRYLDWIHGHIRDKEAPQKSWAP
Glycosylation Sites
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Cell surface interactions at the vascular wall | Homo sapiens |
| Common Pathway of Fibrin Clot Formation | Homo sapiens |
| Gamma-carboxylation of protein precursors | Homo sapiens |
| Intrinsic Pathway of Fibrin Clot Formation | Homo sapiens |
| Post-translational protein phosphorylation | Homo sapiens |
| Regulation of IGF Activity by IGFBP | Homo sapiens |
| Removal of aminoterminal propeptides from gamma-carboxylated proteins | Homo sapiens |
| Transport of gamma-carboxylated protein precursors from the endoplasmic reticulum to the Golgi apparatus | Homo sapiens |
