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Fibrinogen alpha chain [Cleaved into: Fibrinopeptide A; Fibrinogen alpha chain]

Summary

GlyCosmos Lectin: GL_005388
Organism: Homo sapiens (human)

External Links

UniProt: P02671
UniLectin: P02671

Annotation

Keyword: 3D-structure Adaptive immunity Alternative splicing Amyloid Amyloidosis Blood coagulation Calcium Coiled coil Direct protein sequencing Disease variant Disulfide bond Glycoprotein Hydroxylation Innate immunity Isopeptide bond Metal-binding Phosphoprotein Proteomics identification Reference proteome Secreted Signal

Gene Ontology (GO)

Displaying entries **1 - 5** of 38 in total

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GO Term	Evidence Code	Reference
adaptive immune response
cell-matrix adhesion	IDA	PMID
plasminogen activation	IDA	PMID
plasminogen activation	IEA	GO_REF
positive regulation of heterotypic cell-cell adhesion	IDA	PMID

GO Hierarchy

biological process

immune system process [inference]

immune response [inference]

adaptive immune response

humoral immune response [inference]

antimicrobial humoral response [inference]

antibacterial humoral response [inference]

induction of bacterial agglutination

innate immune response

cellular process [inference]

cell adhesion [inference]

cell-substrate adhesion [inference]

cell-matrix adhesion

cell-cell adhesion [inference]

homotypic cell-cell adhesion [inference]

platelet aggregation

metabolic process [inference]

macromolecule metabolic process [inference]

protein metabolic process [inference]

proteolysis [inference]

protein processing [inference]

zymogen activation [inference]

plasminogen activation

protein maturation [inference]

protein processing [inference]

zymogen activation [inference]

plasminogen activation

protein activation cascade [inference]

primary metabolic process [inference]

protein metabolic process [inference]

proteolysis [inference]

protein processing [inference]

zymogen activation [inference]

plasminogen activation

protein maturation [inference]

protein processing [inference]

zymogen activation [inference]

plasminogen activation

protein activation cascade [inference]

cellular component organization or biogenesis [inference]

cellular component organization [inference]

cellular component assembly [inference]

protein-containing complex assembly

protein polymerization

protein-containing complex organization [inference]

protein-containing complex assembly

protein polymerization

multicellular organismal process [inference]

system process [inference]

circulatory system process [inference]

vascular process in circulatory system [inference]

blood vessel diameter maintenance [inference]

regulation of vasoconstriction [inference]

positive regulation of vasoconstriction

biological process involved in interspecies interaction between organisms [inference]

response to other organism [inference]

response to bacterium [inference]

defense response to bacterium [inference]

antibacterial humoral response [inference]

induction of bacterial agglutination

defense response to other organism [inference]

defense response to symbiont [inference]

antimicrobial humoral response [inference]

antibacterial humoral response [inference]

induction of bacterial agglutination

innate immune response

response to stimulus [inference]

response to stress [inference]

defense response [inference]

defense response to bacterium [inference]

antibacterial humoral response [inference]

induction of bacterial agglutination

defense response to other organism [inference]

defense response to symbiont [inference]

antimicrobial humoral response [inference]

antibacterial humoral response [inference]

induction of bacterial agglutination

innate immune response

immune response [inference]

adaptive immune response

humoral immune response [inference]

antimicrobial humoral response [inference]

antibacterial humoral response [inference]

induction of bacterial agglutination

innate immune response

response to external stimulus [inference]

response to external biotic stimulus [inference]

response to other organism [inference]

response to bacterium [inference]

defense response to bacterium [inference]

antibacterial humoral response [inference]

induction of bacterial agglutination

defense response to other organism [inference]

defense response to symbiont [inference]

antimicrobial humoral response [inference]

antibacterial humoral response [inference]

induction of bacterial agglutination

innate immune response

response to biotic stimulus [inference]

response to external biotic stimulus [inference]

response to other organism [inference]

response to bacterium [inference]

defense response to bacterium [inference]

antibacterial humoral response [inference]

induction of bacterial agglutination

defense response to other organism [inference]

defense response to symbiont [inference]

antimicrobial humoral response [inference]

antibacterial humoral response [inference]

induction of bacterial agglutination

innate immune response

response to chemical [inference]

response to metal ion [inference]

response to calcium ion

biological regulation [inference]

regulation of biological process [inference]

regulation of signaling [inference]

regulation of signal transduction [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of MAPK cascade [inference]

positive regulation of ERK1 and ERK2 cascade

negative regulation of signal transduction [inference]

negative regulation of apoptotic signaling pathway [inference]

negative regulation of extrinsic apoptotic signaling pathway [inference]

negative regulation of extrinsic apoptotic signaling pathway via death domain receptors

regulation of intracellular signal transduction [inference]

regulation of MAPK cascade [inference]

positive regulation of MAPK cascade [inference]

positive regulation of ERK1 and ERK2 cascade

regulation of ERK1 and ERK2 cascade [inference]

positive regulation of ERK1 and ERK2 cascade

positive regulation of intracellular signal transduction [inference]

positive regulation of MAPK cascade [inference]

positive regulation of ERK1 and ERK2 cascade

regulation of apoptotic signaling pathway [inference]

negative regulation of apoptotic signaling pathway [inference]

negative regulation of extrinsic apoptotic signaling pathway [inference]

negative regulation of extrinsic apoptotic signaling pathway via death domain receptors

regulation of extrinsic apoptotic signaling pathway [inference]

regulation of extrinsic apoptotic signaling pathway via death domain receptors [inference]

negative regulation of extrinsic apoptotic signaling pathway via death domain receptors

negative regulation of extrinsic apoptotic signaling pathway [inference]

negative regulation of extrinsic apoptotic signaling pathway via death domain receptors

positive regulation of signaling [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of MAPK cascade [inference]

positive regulation of ERK1 and ERK2 cascade

positive regulation of hormone secretion [inference]

positive regulation of peptide hormone secretion

negative regulation of signaling [inference]

negative regulation of signal transduction [inference]

negative regulation of apoptotic signaling pathway [inference]

negative regulation of extrinsic apoptotic signaling pathway [inference]

negative regulation of extrinsic apoptotic signaling pathway via death domain receptors

regulation of hormone secretion [inference]

positive regulation of hormone secretion [inference]

positive regulation of peptide hormone secretion

regulation of peptide hormone secretion [inference]

positive regulation of peptide hormone secretion

regulation of localization [inference]

regulation of protein localization [inference]

regulation of establishment of protein localization [inference]

regulation of protein transport [inference]

regulation of protein secretion [inference]

positive regulation of protein secretion

positive regulation of protein transport [inference]

positive regulation of protein secretion

positive regulation of establishment of protein localization [inference]

positive regulation of protein transport [inference]

positive regulation of protein secretion

positive regulation of protein localization [inference]

positive regulation of protein transport [inference]

positive regulation of protein secretion

regulation of transport [inference]

regulation of secretion [inference]

regulation of peptide secretion [inference]

positive regulation of peptide secretion [inference]

positive regulation of peptide hormone secretion

regulation of peptide hormone secretion [inference]

positive regulation of peptide hormone secretion

positive regulation of secretion [inference]

positive regulation of peptide secretion [inference]

positive regulation of peptide hormone secretion

positive regulation of secretion by cell [inference]

positive regulation of exocytosis

positive regulation of hormone secretion [inference]

positive regulation of peptide hormone secretion

positive regulation of protein secretion

regulation of secretion by cell [inference]

regulation of exocytosis [inference]

positive regulation of exocytosis

regulation of hormone secretion [inference]

positive regulation of hormone secretion [inference]

positive regulation of peptide hormone secretion

regulation of peptide hormone secretion [inference]

positive regulation of peptide hormone secretion

regulation of protein secretion [inference]

positive regulation of protein secretion

positive regulation of secretion by cell [inference]

positive regulation of exocytosis

positive regulation of hormone secretion [inference]

positive regulation of peptide hormone secretion

positive regulation of protein secretion

positive regulation of transport [inference]

positive regulation of secretion [inference]

positive regulation of peptide secretion [inference]

positive regulation of peptide hormone secretion

positive regulation of secretion by cell [inference]

positive regulation of exocytosis

positive regulation of hormone secretion [inference]

positive regulation of peptide hormone secretion

positive regulation of protein secretion

positive regulation of protein transport [inference]

positive regulation of protein secretion

regulation of protein transport [inference]

regulation of protein secretion [inference]

positive regulation of protein secretion

positive regulation of protein transport [inference]

positive regulation of protein secretion

regulation of vesicle-mediated transport [inference]

regulation of exocytosis [inference]

positive regulation of exocytosis

regulation of peptide transport [inference]

regulation of peptide secretion [inference]

positive regulation of peptide secretion [inference]

positive regulation of peptide hormone secretion

regulation of peptide hormone secretion [inference]

positive regulation of peptide hormone secretion

positive regulation of biological process [inference]

positive regulation of signaling [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of MAPK cascade [inference]

positive regulation of ERK1 and ERK2 cascade

positive regulation of hormone secretion [inference]

positive regulation of peptide hormone secretion

positive regulation of cellular process [inference]

positive regulation of cell communication [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of MAPK cascade [inference]

positive regulation of ERK1 and ERK2 cascade

positive regulation of hormone secretion [inference]

positive regulation of peptide hormone secretion

positive regulation of cell adhesion [inference]

positive regulation of cell-substrate adhesion [inference]

positive regulation of substrate adhesion-dependent cell spreading

positive regulation of cell-cell adhesion [inference]

positive regulation of heterotypic cell-cell adhesion

positive regulation of secretion by cell [inference]

positive regulation of exocytosis

positive regulation of hormone secretion [inference]

positive regulation of peptide hormone secretion

positive regulation of protein secretion

positive regulation of response to stimulus [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of MAPK cascade [inference]

positive regulation of ERK1 and ERK2 cascade

positive regulation of transport [inference]

positive regulation of secretion [inference]

positive regulation of peptide secretion [inference]

positive regulation of peptide hormone secretion

positive regulation of secretion by cell [inference]

positive regulation of exocytosis

positive regulation of hormone secretion [inference]

positive regulation of peptide hormone secretion

positive regulation of protein secretion

positive regulation of protein transport [inference]

positive regulation of protein secretion

positive regulation of multicellular organismal process [inference]

positive regulation of vasoconstriction

positive regulation of protein localization [inference]

positive regulation of protein transport [inference]

positive regulation of protein secretion

positive regulation of establishment of protein localization [inference]

positive regulation of protein transport [inference]

positive regulation of protein secretion

negative regulation of biological process [inference]

negative regulation of signaling [inference]

negative regulation of signal transduction [inference]

negative regulation of apoptotic signaling pathway [inference]

negative regulation of extrinsic apoptotic signaling pathway [inference]

negative regulation of extrinsic apoptotic signaling pathway via death domain receptors

negative regulation of cellular process [inference]

negative regulation of cell communication [inference]

negative regulation of signal transduction [inference]

negative regulation of apoptotic signaling pathway [inference]

negative regulation of extrinsic apoptotic signaling pathway [inference]

negative regulation of extrinsic apoptotic signaling pathway via death domain receptors

negative regulation of programmed cell death [inference]

negative regulation of apoptotic process [inference]

negative regulation of endothelial cell apoptotic process

negative regulation of apoptotic signaling pathway [inference]

negative regulation of extrinsic apoptotic signaling pathway [inference]

negative regulation of extrinsic apoptotic signaling pathway via death domain receptors

negative regulation of response to stimulus [inference]

negative regulation of signal transduction [inference]

negative regulation of apoptotic signaling pathway [inference]

negative regulation of extrinsic apoptotic signaling pathway [inference]

negative regulation of extrinsic apoptotic signaling pathway via death domain receptors

negative regulation of response to external stimulus [inference]

negative regulation of wound healing [inference]

negative regulation of blood coagulation [inference]

fibrinolysis

negative regulation of response to wounding [inference]

negative regulation of wound healing [inference]

negative regulation of blood coagulation [inference]

fibrinolysis

negative regulation of multicellular organismal process [inference]

negative regulation of coagulation [inference]

negative regulation of blood coagulation [inference]

fibrinolysis

negative regulation of hemostasis [inference]

negative regulation of blood coagulation [inference]

fibrinolysis

regulation of response to stimulus [inference]

regulation of signal transduction [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of MAPK cascade [inference]

positive regulation of ERK1 and ERK2 cascade

negative regulation of signal transduction [inference]

negative regulation of apoptotic signaling pathway [inference]

negative regulation of extrinsic apoptotic signaling pathway [inference]

negative regulation of extrinsic apoptotic signaling pathway via death domain receptors

regulation of intracellular signal transduction [inference]

regulation of MAPK cascade [inference]

positive regulation of MAPK cascade [inference]

positive regulation of ERK1 and ERK2 cascade

regulation of ERK1 and ERK2 cascade [inference]

positive regulation of ERK1 and ERK2 cascade

positive regulation of intracellular signal transduction [inference]

positive regulation of MAPK cascade [inference]

positive regulation of ERK1 and ERK2 cascade

regulation of apoptotic signaling pathway [inference]

negative regulation of apoptotic signaling pathway [inference]

negative regulation of extrinsic apoptotic signaling pathway [inference]

negative regulation of extrinsic apoptotic signaling pathway via death domain receptors

regulation of extrinsic apoptotic signaling pathway [inference]

regulation of extrinsic apoptotic signaling pathway via death domain receptors [inference]

negative regulation of extrinsic apoptotic signaling pathway via death domain receptors

negative regulation of extrinsic apoptotic signaling pathway [inference]

negative regulation of extrinsic apoptotic signaling pathway via death domain receptors

regulation of response to external stimulus [inference]

regulation of blood coagulation [inference]

negative regulation of blood coagulation [inference]

fibrinolysis

negative regulation of response to external stimulus [inference]

negative regulation of wound healing [inference]

negative regulation of blood coagulation [inference]

fibrinolysis

positive regulation of response to stimulus [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of MAPK cascade [inference]

positive regulation of ERK1 and ERK2 cascade

negative regulation of response to stimulus [inference]

negative regulation of signal transduction [inference]

negative regulation of apoptotic signaling pathway [inference]

negative regulation of extrinsic apoptotic signaling pathway [inference]

negative regulation of extrinsic apoptotic signaling pathway via death domain receptors

negative regulation of response to external stimulus [inference]

negative regulation of wound healing [inference]

negative regulation of blood coagulation [inference]

fibrinolysis

negative regulation of response to wounding [inference]

negative regulation of wound healing [inference]

negative regulation of blood coagulation [inference]

fibrinolysis

regulation of response to stress [inference]

regulation of response to wounding [inference]

regulation of wound healing [inference]

regulation of blood coagulation [inference]

negative regulation of blood coagulation [inference]

fibrinolysis

negative regulation of wound healing [inference]

negative regulation of blood coagulation [inference]

fibrinolysis

negative regulation of response to wounding [inference]

negative regulation of wound healing [inference]

negative regulation of blood coagulation [inference]

fibrinolysis

regulation of cellular process [inference]

regulation of cell communication [inference]

regulation of signal transduction [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of MAPK cascade [inference]

positive regulation of ERK1 and ERK2 cascade

negative regulation of signal transduction [inference]

negative regulation of apoptotic signaling pathway [inference]

negative regulation of extrinsic apoptotic signaling pathway [inference]

negative regulation of extrinsic apoptotic signaling pathway via death domain receptors

regulation of intracellular signal transduction [inference]

regulation of MAPK cascade [inference]

positive regulation of MAPK cascade [inference]

positive regulation of ERK1 and ERK2 cascade

regulation of ERK1 and ERK2 cascade [inference]

positive regulation of ERK1 and ERK2 cascade

positive regulation of intracellular signal transduction [inference]

positive regulation of MAPK cascade [inference]

positive regulation of ERK1 and ERK2 cascade

regulation of apoptotic signaling pathway [inference]

negative regulation of apoptotic signaling pathway [inference]

negative regulation of extrinsic apoptotic signaling pathway [inference]

negative regulation of extrinsic apoptotic signaling pathway via death domain receptors

regulation of extrinsic apoptotic signaling pathway [inference]

regulation of extrinsic apoptotic signaling pathway via death domain receptors [inference]

negative regulation of extrinsic apoptotic signaling pathway via death domain receptors

negative regulation of extrinsic apoptotic signaling pathway [inference]

negative regulation of extrinsic apoptotic signaling pathway via death domain receptors

positive regulation of cell communication [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of MAPK cascade [inference]

positive regulation of ERK1 and ERK2 cascade

positive regulation of hormone secretion [inference]

positive regulation of peptide hormone secretion

negative regulation of cell communication [inference]

negative regulation of signal transduction [inference]

negative regulation of apoptotic signaling pathway [inference]

negative regulation of extrinsic apoptotic signaling pathway [inference]

negative regulation of extrinsic apoptotic signaling pathway via death domain receptors

regulation of hormone secretion [inference]

positive regulation of hormone secretion [inference]

positive regulation of peptide hormone secretion

regulation of peptide hormone secretion [inference]

positive regulation of peptide hormone secretion

regulation of cell adhesion [inference]

regulation of cell-substrate adhesion [inference]

positive regulation of cell-substrate adhesion [inference]

positive regulation of substrate adhesion-dependent cell spreading

regulation of substrate adhesion-dependent cell spreading [inference]

positive regulation of substrate adhesion-dependent cell spreading

regulation of cell-cell adhesion [inference]

positive regulation of cell-cell adhesion [inference]

positive regulation of heterotypic cell-cell adhesion

regulation of heterotypic cell-cell adhesion [inference]

positive regulation of heterotypic cell-cell adhesion

positive regulation of cell adhesion [inference]

positive regulation of cell-substrate adhesion [inference]

positive regulation of substrate adhesion-dependent cell spreading

positive regulation of cell-cell adhesion [inference]

positive regulation of heterotypic cell-cell adhesion

regulation of programmed cell death [inference]

regulation of apoptotic process [inference]

negative regulation of apoptotic process [inference]

negative regulation of endothelial cell apoptotic process

negative regulation of apoptotic signaling pathway [inference]

negative regulation of extrinsic apoptotic signaling pathway [inference]

negative regulation of extrinsic apoptotic signaling pathway via death domain receptors

regulation of endothelial cell apoptotic process [inference]

negative regulation of endothelial cell apoptotic process

regulation of apoptotic signaling pathway [inference]

negative regulation of apoptotic signaling pathway [inference]

negative regulation of extrinsic apoptotic signaling pathway [inference]

negative regulation of extrinsic apoptotic signaling pathway via death domain receptors

regulation of extrinsic apoptotic signaling pathway [inference]

regulation of extrinsic apoptotic signaling pathway via death domain receptors [inference]

negative regulation of extrinsic apoptotic signaling pathway via death domain receptors

negative regulation of extrinsic apoptotic signaling pathway [inference]

negative regulation of extrinsic apoptotic signaling pathway via death domain receptors

negative regulation of programmed cell death [inference]

negative regulation of apoptotic process [inference]

negative regulation of endothelial cell apoptotic process

negative regulation of apoptotic signaling pathway [inference]

negative regulation of extrinsic apoptotic signaling pathway [inference]

negative regulation of extrinsic apoptotic signaling pathway via death domain receptors

positive regulation of cellular process [inference]

positive regulation of cell communication [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of MAPK cascade [inference]

positive regulation of ERK1 and ERK2 cascade

positive regulation of hormone secretion [inference]

positive regulation of peptide hormone secretion

positive regulation of cell adhesion [inference]

positive regulation of cell-substrate adhesion [inference]

positive regulation of substrate adhesion-dependent cell spreading

positive regulation of cell-cell adhesion [inference]

positive regulation of heterotypic cell-cell adhesion

positive regulation of secretion by cell [inference]

positive regulation of exocytosis

positive regulation of hormone secretion [inference]

positive regulation of peptide hormone secretion

positive regulation of protein secretion

negative regulation of cellular process [inference]

negative regulation of cell communication [inference]

negative regulation of signal transduction [inference]

negative regulation of apoptotic signaling pathway [inference]

negative regulation of extrinsic apoptotic signaling pathway [inference]

negative regulation of extrinsic apoptotic signaling pathway via death domain receptors

negative regulation of programmed cell death [inference]

negative regulation of apoptotic process [inference]

negative regulation of endothelial cell apoptotic process

negative regulation of apoptotic signaling pathway [inference]

negative regulation of extrinsic apoptotic signaling pathway [inference]

negative regulation of extrinsic apoptotic signaling pathway via death domain receptors

regulation of vesicle-mediated transport [inference]

regulation of exocytosis [inference]

positive regulation of exocytosis

regulation of secretion by cell [inference]

regulation of exocytosis [inference]

positive regulation of exocytosis

regulation of hormone secretion [inference]

positive regulation of hormone secretion [inference]

positive regulation of peptide hormone secretion

regulation of peptide hormone secretion [inference]

positive regulation of peptide hormone secretion

regulation of protein secretion [inference]

positive regulation of protein secretion

positive regulation of secretion by cell [inference]

positive regulation of exocytosis

positive regulation of hormone secretion [inference]

positive regulation of peptide hormone secretion

positive regulation of protein secretion

regulation of multicellular organismal process [inference]

regulation of system process [inference]

regulation of blood circulation [inference]

regulation of vasoconstriction [inference]

positive regulation of vasoconstriction

regulation of coagulation [inference]

regulation of blood coagulation [inference]

negative regulation of blood coagulation [inference]

fibrinolysis

negative regulation of coagulation [inference]

negative regulation of blood coagulation [inference]

fibrinolysis

positive regulation of multicellular organismal process [inference]

positive regulation of vasoconstriction

negative regulation of multicellular organismal process [inference]

negative regulation of coagulation [inference]

negative regulation of blood coagulation [inference]

fibrinolysis

regulation of hemostasis [inference]

regulation of blood coagulation [inference]

negative regulation of blood coagulation [inference]

fibrinolysis

negative regulation of hemostasis [inference]

negative regulation of blood coagulation [inference]

fibrinolysis

regulation of biological quality [inference]

regulation of hormone levels [inference]

regulation of hormone secretion [inference]

positive regulation of hormone secretion [inference]

positive regulation of peptide hormone secretion

regulation of peptide hormone secretion [inference]

positive regulation of peptide hormone secretion

regulation of body fluid levels [inference]

regulation of hemostasis [inference]

regulation of blood coagulation [inference]

negative regulation of blood coagulation [inference]

fibrinolysis

negative regulation of hemostasis [inference]

negative regulation of blood coagulation [inference]

fibrinolysis

regulation of anatomical structure size [inference]

regulation of tube size [inference]

regulation of tube diameter [inference]

blood vessel diameter maintenance [inference]

regulation of vasoconstriction [inference]

positive regulation of vasoconstriction

Displaying entries **6 - 10** of 24 in total

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GO Term	Evidence Code	Reference
fibrinogen complex	TAS	PMID
fibrinogen complex	IDA	PMID PMID PMID
fibrinogen complex	IBA	GO_REF
fibrinogen complex	IPI	PMID
fibrinogen complex	IEA	GO_REF GO_REF

GO Hierarchy

cellular component

protein-containing complex [inference]

extracellular protein-containing complex [inference]

fibrinogen complex

cellular anatomical structure [inference]

membrane [inference]

plasma membrane

external encapsulating structure [inference]

extracellular matrix

membrane-enclosed lumen [inference]

organelle lumen [inference]

vesicle lumen [inference]

cytoplasmic vesicle lumen [inference]

secretory granule lumen [inference]

platelet alpha granule lumen

intracellular organelle lumen [inference]

endoplasmic reticulum lumen

cytoplasmic vesicle lumen [inference]

secretory granule lumen [inference]

platelet alpha granule lumen

organelle [inference]

membrane-bounded organelle [inference]

vesicle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

secretory vesicle [inference]

secretory granule [inference]

platelet alpha granule

extracellular vesicle

extracellular exosome

intracellular membrane-bounded organelle [inference]

endoplasmic reticulum

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

secretory vesicle [inference]

secretory granule [inference]

platelet alpha granule

extracellular membrane-bounded organelle [inference]

extracellular vesicle

extracellular exosome

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

endoplasmic reticulum

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

secretory vesicle [inference]

secretory granule [inference]

platelet alpha granule

extracellular organelle [inference]

extracellular membrane-bounded organelle [inference]

extracellular vesicle

extracellular exosome

blood microparticle

side of membrane [inference]

external side of plasma membrane

Displaying entries **1 - 5** of 8 in total

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GO Term	Evidence Code	Reference
signaling receptor binding	IDA	PMID
signaling receptor binding	IEA	GO_REF
structural molecule activity	IDA	PMID
structural molecule activity	IMP	PMID
extracellular matrix structural constituent	RCA	PMID PMID

GO Hierarchy

molecular function

structural molecule activity

extracellular matrix structural constituent

binding [inference]

protein binding [inference]

signaling receptor binding

small molecule binding [inference]

ion binding [inference]

cation binding [inference]

metal ion binding

molecular adaptor activity [inference]

protein-macromolecule adaptor activity

Gene Ontology information from UniProt.

Annotation information from UniProt.

Pathway

Displaying entries **1 - 10** of 22 in total

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Pathway Name	Organism
Aggregated β-amyloid interacts with fibrinogen	Homo sapiens
Amyloid fiber formation	Homo sapiens
ER-Phagosome pathway	Homo sapiens
Fibrin formation	Homo sapiens
GRB2:SOS provides linkage to MAPK signaling for Integrins	Homo sapiens
IRAK4 deficiency (TLR2/4)	Homo sapiens
Integrin cell surface interactions	Homo sapiens
Integrin signaling	Homo sapiens
MAP2K and MAPK activation	Homo sapiens
MyD88 deficiency (TLR2/4)	Homo sapiens