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Acyl chain remodelling of PI

Summary

Organism

Homo sapiens (human)

Reactome

R-HSA-1482922

PubChem

R-HSA-1482922

Description

In the acyl chain remodelling pathway (Lands cycle), phosphatidylinositol (PI) is hydrolyzed by phospholipases and subsequently reacylated by acyltransferases. These cycles modify the fatty acid composition of glycerophospholipids to generate diverse molecules asymmetrically distributed in the cell membrane (Ghomashchi et al. 2010, Singer et al. 2002, Gijon et al. 2008, Lee et al. 2008).

Click on a node on the pathway to see its details. Glycoproteins are marked with a glycoprotein icon in their name.

SPV: a JavaScript Signaling Pathway Visualizer, Bioinformatics, 2018

Displaying **all 9** entries
UniProt ID	Protein Name	Gene Symbol	Pathway Viewer
O15496	Group 10 secretory phospholipase A2	PLA2G10	view
P14555	Phospholipase A2, membrane associated	PLA2B PLA2G2A PLA2L RASF-A	view
P47712	Cytosolic phospholipase A2	CPLA2 PLA2G4 PLA2G4A	view
Q13018	Secretory phospholipase A2 receptor	CLEC13C PLA2R1	view
Q6P4A8	Lysosomal leucine aminopeptidase	Lylap PLBD1	view
Q96N66	Membrane-bound acylglycerophosphatidylinositol O-acyltransferase MBOAT7	BB1 LENG4 MBOAT7 OACT7	view
Q9BZM2	Group IIF secretory phospholipase A2	PLA2G2F	view
Q9NZK7	Group IIE secretory phospholipase A2	PLA2G2E	view
Q9UNK4	Group IID secretory phospholipase A2	PLA2G2D SPLASH	view

Displaying 1 entry
GlyCosmos Lectin	UniProt ID	Lectin Name	Pathway Viewer
GL_001087	Q13018	Secretory phospholipase A2 receptor	view

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