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NFE2L2 regulating tumorigenic genes

Summary

Organism

Homo sapiens (human)

Reactome

R-HSA-9818030

PubChem

R-HSA-9818030

Description

Sub-pathway representing tumor-inducing genes regulated by NFE2L2 (NRF2). NFE2L2 plays a key role in cancer progression by inducing cytoprotection, regulating cancer metabolism and also directly regulating the expression of pro-tumorogenic genes(Deblasi et al, 2020; Wu et al, 2019)

Click on a node on the pathway to see its details. Glycoproteins are marked with a glycoprotein icon in their name.

SPV: a JavaScript Signaling Pathway Visualizer, Bioinformatics, 2018

Displaying **all 9** entries
UniProt ID	Protein Name	Gene Symbol	Pathway Viewer
O60675	Transcription factor MafK	MAFK	view
P01133	Pro-epidermal growth factor	EGF	view
P04085	Platelet-derived growth factor subunit A	PDGF1 PDGFA	view
P08047	Transcription factor Sp1	SP1 TSFP1	view
P15514	Amphiregulin	AREG AREGB SDGF	view
P46531	Neurogenic locus notch homolog protein 1	NOTCH1 TAN1	view
Q09472	Histone acetyltransferase p300	EP300 P300	view
Q16236	Nuclear factor erythroid 2-related factor 2	NFE2L2 NRF2	view
Q92793	CREB-binding protein	CBP CREBBP	view

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