GlyCosmos Portal

Submissions

Interaction of NuRD complexes with transcription factors

Summary

Organism

Homo sapiens (human)

Reactome

R-HSA-9940951

PubChem

R-HSA-9940951

Description

Numerous histone and DNA-binding domains in CHD, MTA, MBD and RBBP proteins contribute to the recruitment of the NuRD complex to DNA, where it appears to interact simultaneously with two adjacent nucleosomes (reviewed in Asamamaw et al, 2024; Reid et al, 2023). Recruitment to specific target genes is additionally mediated by protein-protein interactions between NuRD complex components and sequence-specific transcription factors, some of which are represented in this pathway (reviewed in Reid et al, 2023).

Click on a node on the pathway to see its details. Glycoproteins are marked with a glycoprotein icon in their name.

SPV: a JavaScript Signaling Pathway Visualizer, Bioinformatics, 2018

Displaying entries **1 - 10** of 47 in total

1

2

3

4

5

Next ›

Last »
UniProt ID	Protein Name	Gene Symbol	Pathway Viewer
O14519	Cyclin-dependent kinase 2-associated protein 1	CDK2AP1 CDKAP1 DOC1	view
O60814	Histone H2B type 1-K	H2BC12 H2BFT HIRIP1 HIST1H2BK	view
O75956	Cyclin-dependent kinase 2-associated protein 2	CDK2AP2 DOC1R	view
O95983	Methyl-CpG-binding domain protein 3	MBD3	view
P04908	Histone H2A type 1-B/E	H2AC4; H2AC8 H2AFA H2AFM HIST1H2AB HIST1H2AE	view
P06899	Histone H2B type 1-J	H2BC11 H2BFR HIST1H2BJ	view
P09467	Fructose-1,6-bisphosphatase 1	FBP FBP1	view
P16104	Histone H2AX	H2AFX H2AX	view
P23527	Histone H2B type 1-O	H2BC17 H2BFH H2BFN HIST1H2BO	view
P24468	COUP transcription factor 2	ARP1 NR2F2 TFCOUP2	view

Displaying 1 entry
GlyCosmos Lectin	UniProt ID	Lectin Name	Pathway Viewer
GL_003393	P09467	Fructose-1,6-bisphosphatase 1	view

If you want to check the location of a particular molecule, you can do so by clicking on the "Switching Highlight" button on the page you have navigated to by clicking on "view".

About Release Notes Help Feedback

Click here to visit the beta site.