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Antigen activates B Cell Receptor (BCR) leading to generation of second messengers

Summary

Organism

Mus musculus (house mouse)

Reactome

R-MMU-983695

PubChem

R-MMU-983695

Description

This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Click on a node on the pathway to see its details. Glycoproteins are marked with a glycoprotein icon in their name.

SPV: a JavaScript Signaling Pathway Visualizer, Bioinformatics, 2018

Displaying entries **1 - 10** of 11 in total

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UniProt ID	Protein Name	Gene Symbol	Pathway Viewer
P01872	Immunoglobulin heavy constant mu	Igh-6 Ighm	view
P11881	Inositol 1,4,5-trisphosphate-gated calcium channel ITPR1	Insp3r Itpr1 Pcd6 Pcp1	view
P11911	B-cell antigen receptor complex-associated protein alpha chain	Cd79a Iga Mb-1	view
P15530	B-cell antigen receptor complex-associated protein beta chain	Cd79b Igb	view
P25918	B-lymphocyte antigen CD19	Cd19	view
P26450	Phosphatidylinositol 3-kinase regulatory subunit alpha	Pik3r1	view
P29351	Tyrosine-protein phosphatase non-receptor type 6	Hcp Hcph Ptp1C Ptpn6	view
P35329	B-cell receptor CD22	Cd22 Lyb-8 Siglec2	view
P35991	Tyrosine-protein kinase BTK	Bpk Btk	view
P70227	Inositol 1,4,5-trisphosphate-gated calcium channel ITPR3	Itpr3	view

Displaying 1 entry
GlyCosmos Lectin	UniProt ID	Lectin Name	Pathway Viewer
GL_000078	P35329	B-cell receptor CD22	view

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