pulmonary hypertension

Summary
Definition
A hypertension characterized by an increase of blood pressure in the pulmonary artery, pulmonary vein or pulmonary capillaries.
Super Class
hypertension
Disease Ontology
DOID:6432
Mondo Disease Ontology
MeSH
UMLS
NCI Thesaurus
MGI genotype (from TogoID)
WikiPathways (from TogoID)
Related Genes
Displaying entries 1 - 10 of 26 in total
Gene ID Gene Symbol Description Source
94 ACVRL1 activin A receptor like type 1
133 ADM adrenomedullin
185 AGTR1 angiotensin II receptor type 1
240 ALOX5 arachidonate 5-lipoxygenase
488 ATP2A2 ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2
659 BMPR2 bone morphogenetic protein receptor type 2
1440 CSF3 colony stimulating factor 3
1573 CYP2J2 cytochrome P450 family 2 subfamily J member 2
1909 EDNRA endothelin receptor type A
2034 EPAS1 endothelial PAS domain protein 1
Displaying 1 entry
Gene ID Gene Symbol Description Source
19285 Cavin1 caveolae associated 1
Displaying entries 11 - 20 of 27 in total
Gene ID Gene Symbol Description Source
25459 Hmgb1 high mobility group box 1
25553 Slc6a4 solute carrier family 6 member 4
25675 Hmgcr 3-hydroxy-3-methylglutaryl-CoA reductase
29527 Ptgs2 prostaglandin-endoperoxide synthase 2
29553 Kcnk3 potassium two pore domain channel subfamily K member 3
29583 Pecam1 platelet and endothelial cell adhesion molecule 1
29591 Tgfbr1 transforming growth factor, beta receptor 1
50672 Ednrb endothelin receptor type B
60628 Cxcr4 C-X-C motif chemokine receptor 4
65262 Atp5f1a ATP synthase F1 subunit alpha
Related Glycoprotein
Displaying 1 entry
UniProt ID Protein Name Source
O54724 Caveolae-associated protein 1

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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01


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Last updated: August 4, 2025