G00033MO

Summary
GlyTouCan ID
G00033MO
IUPAC Condensed
Gal(b1-3)[GlcNAc(b1-6)]GalNAc(a1-
Motifs
O-Glycan core 2
Subsumption Level
Fully-defined saccharide
Monoisotopic Mass
586.22
GlyConnect structure
GlyGen
ChEBI
PubChem Compound
PubChem Substance
3D Structures
GlycoShape
G00033MO
Displaying 1 entry
Archetype α β
G00034MO
G00033MO
G24720OO
Organisms
Taxonomic Hierarchy
GlycoGene Database (GGDB)
Displaying all 4 entries
Gene Symbol Donor Acceptor Reducing terminal(Acceptor) Product Reducing terminal(Product) Reference
B3GALNT2 UDP-GalNAc
G00033MO
Ser/Thr
G01707KB
Ser/Thr
GCNT1 UDP-GlcNAc
G00031MO
Ser/Thr (core 2)
G00033MO
Ser/Thr (core 2)
GCNT4 UDP-GlcNAc
G00031MO
Ser/Thr
G00033MO
Ser/Thr
GCNT3 UDP-GlcNAc
G00031MO
Ser/Thr
G00033MO
Ser/Thr
Displaying entries 21 - 22 of 22 in total
Gene Symbol Donor Acceptor Reducing terminal(Acceptor) Product Reducing terminal(Product) Reference
GCNT3 UDP-GlcNAc
G00031MO
Ser/Thr
G00033MO
Ser/Thr
B3GNT3 UDP-GlcNAc
G00033MO
[alpha]p-nitrophenol
G68893BQ
[alpha]p-nitrophenol
Displaying all 4 entries
Gene Symbol Donor Acceptor Reducing terminal(Acceptor) Reference
GAL3ST3 PAPS
G00033MO
octyl
B3GNT8 UDP-GlcNAc
G00033MO
core 2-pNp
B3GNT6 UDP-GlcNAc
G00033MO
[alpha]-pNP(core 2)
B3GNT7 UDP-GlcNAc
G00033MO
core 2-pNp
KEGG BRITE Database
Sequence Descriptors
GlycoCT
RES
1b:a-dgal-HEX-1:5
2s:n-acetyl
3b:b-dgal-HEX-1:5
4b:b-dglc-HEX-1:5
5s:n-acetyl
LIN
1:1d(2+1)2n
2:1o(3+1)3d
3:1o(6+1)4d
4:4d(2+1)5n
WURCS
WURCS=2.0/3,3,2/[a2112h-1a_1-5_2*NCC/3=O][a2112h-1b_1-5][a2122h-1b_1-5_2*NCC/3=O]/1-2-3/a3-b1_a6-c1
Literature
Displaying entries 11 - 20 of 42 in total
PubMed ID Title First Author Publication Date Source
18725413 The Diversity of O-Linked Glycans Expressed during Drosophila melanogaster Development Reflects Stage- and Tissue-specific Requirements for Cell Signaling Aoki K 2008 Oct 31
  • GlyGen
15620693 A novel β1,3‐N‐acetylglucosaminyltransferase (β3Gn‐T8), which synthesizes poly‐N‐acetyllactosamine, is dramatically upregulated in colon cancer Ishida H 2004 Nov 28
  • PubChem
15044014 Molecular cloning and characterization of β1,4‐N‐acetylgalactosaminyltransferases IV synthesizing N,N′‐diacetyllactosediamine1 Gotoh M 2004 Mar 05
  • PubChem
14724282 A novel human beta1,3-N-acetylgalactosaminyltransferase that synthesizes a unique carbohydrate structure, GalNAcbeta1-3GlcNAc Hiruma T 2004 Apr 02
  • PubChem
12966086 Molecular cloning and characterization of a novel human beta 1,4-N-acetylgalactosaminyltransferase, beta 4GalNAc-T3, responsible for the synthesis of N,N'-diacetyllactosediamine, galNAc beta 1-4GlcNAc Sato T 2003 Nov 28
  • PubChem
14673092 Murine and human zona pellucida 3 derived from mouse eggs express identical O-glycans Dell A 2003 Dec 12
  • GlyGen
  • PubChem
11821425 Molecular cloning and characterization of a novel UDP-GlcNAc:GalNAc-peptide beta1,3-N-acetylglucosaminyltransferase (beta 3Gn-T6), an enzyme synthesizing the core 3 structure of O-glycans Iwai T 2002 Apr 12
  • PubChem
11323440 Molecular cloning and expression of a novel human beta-Gal-3-O-sulfotransferase that acts preferentially on N-acetyllactosamine in N- and O-glycans Suzuki A 2001 Jun 29
  • PubChem
11439191 Novel sulfated lymphocyte homing receptors and their control by a Core1 extension beta 1,3-N-acetylglucosaminyltransferase Yeh JC 2001 Jun 29
  • PubChem
11333265 Molecular cloning and characterization of a novel human galactose 3-O-sulfotransferase that transfers sulfate to gal beta 1-->3galNAc residue in O-glycans Seko A 2001 Jul 13
  • PubChem
PubAnnotation
Displaying entries 1 - 5 of 10 in total
Title Authors Source Publication Date PubMed ID
In-Depth Profiling of O-Glycan Isomers in Human Cells Using C18 Nanoliquid Chromatography-Mass Spectrometry and Glycogenomics.
  • de Haan N
  • Narimatsu Y
  • Koed Møller Aasted M
  • Larsen ISB
  • Marinova IN
  • Dabelsteen S
  • Vakhrushev SY
  • Wandall HH
Anal Chem 2022 Mar 15 35245040
Sulfation of O-glycans on Mucin-type Proteins From Serous Ovarian Epithelial Tumors.
  • Thomsson KA
  • Vitiazeva V
  • Mateoiu C
  • Jin C
  • Liu J
  • Holgersson J
  • Weijdegård B
  • Sundfeldt K
  • Karlsson NG
Mol Cell Proteomics 2021 34555499
Deciphering Isomers with a Multiple Reaction Monitoring Method for the Complete Detectable O-Glycan Repertoire of the Candidate Therapeutic, Lubricin.
  • Flowers SA
  • Lane CS
  • Karlsson NG
Anal Chem 2019 Aug 6 31246420
The O-glycomap of lubricin, a novel mucin responsible for joint lubrication, identified by site-specific glycopeptide analysis.
  • Ali L
  • Flowers SA
  • Jin C
  • Bennet EP
  • Ekwall AK
  • Karlsson NG
Mol Cell Proteomics 2014 Dec 25187573
Almost all human gastric mucin O-glycans harbor blood group A, B or H antigens and are potential binding sites for Helicobacter pylori.
  • Rossez Y
  • Maes E
  • Lefebvre Darroman T
  • Gosset P
  • Ecobichon C
  • Joncquel Chevalier Curt M
  • Boneca IG
  • Michalski JC
  • Robbe-Masselot C
Glycobiology 2012 Sep 22522599

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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01


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