G00052MO

Summary
GlyTouCan ID
G00052MO
IUPAC Condensed
Fuc(a1-2)Gal(b1-4)[Fuc(a1-3)]GlcNAc(b1-
Motifs
Blood group H (type 2) Leb Lewis b Ley
Subsumption Level
Fully-defined saccharide
Monoisotopic Mass
675.26
3D Structures
GlycoShape
G00052MO
Displaying 1 entry
Archetype α β
G04690JX
G82236PZ
G00052MO
Organisms
Taxonomic Hierarchy
GlycoGene Database (GGDB)
Displaying all 2 entries
Gene Symbol Donor Acceptor Reducing terminal(Acceptor) Product Reducing terminal(Product) Reference
FUT5 GDP-Fuc
G61459JW
R
G00052MO
R
FUT3 GDP-Fuc
G61459JW
R
G00052MO
R
Displaying all 5 entries
Gene Symbol Donor Acceptor Reducing terminal(Acceptor) Product Reducing terminal(Product) Reference
FUT5 GDP-Fuc
G61459JW
R
G00052MO
R
FUT5 GDP-Fuc
G61459JW
(CH2)8COOCH3
G00052MO
(CH2)8COOCH3
FUT3 GDP-Fuc
G61459JW
R
G00052MO
R
FUT3 GDP-Fuc
G61459JW
(CH2)8COOCH3
G00052MO
(CH2)8COOCH3
FUT6 GDP-Fuc
G61459JW
(CH2)8COOCH3
G00052MO
(CH2)8COOCH3
GlycoEpitope
Epitope ID
EP0018
Sequence Descriptors
GlycoCT
RES
1b:b-dglc-HEX-1:5
2s:n-acetyl
3b:a-lgal-HEX-1:5|6:d
4b:b-dgal-HEX-1:5
5b:a-lgal-HEX-1:5|6:d
LIN
1:1d(2+1)2n
2:1o(3+1)3d
3:1o(4+1)4d
4:4o(2+1)5d
WURCS
WURCS=2.0/3,4,3/[a2122h-1b_1-5_2*NCC/3=O][a1221m-1a_1-5][a2112h-1b_1-5]/1-2-3-2/a3-b1_a4-c1_c2-d1
Literature
Displaying entries 51 - 60 of 410 in total
PubMed ID Title First Author Publication Date Source
23894390 Co-Expression of Lewis y Antigen with Human Epididymis Protein 4 in Ovarian Epithelial Carcinoma Zhuang H 2013 Jul 22
  • PubChem
23533340 Transcriptional Regulation of Fucosyltransferase 1 Gene Expression in Colon Cancer Cells Taniuchi F 2013 Jan
  • PubChem
23468946 High Expression of Lewis y Antigen and CD44 Is Correlated with Resistance to Chemotherapy in Epithelial Ovarian Cancers Hu Z 2013 Feb 28
  • PubChem
23600498 Structure-Based Peptide Mimicry of Tumor-Associated Antigens Ohtaki A 2013 Feb
  • PubChem
23443083 Elevated Levels of Lewis Y and Integrin α5β1 Correlate with Chemotherapeutic Drug Resistance in Epithelial Ovarian Carcinoma Hu Z 2012 Nov 23
  • PubChem
23128605 Suppression of FUT1 attenuates cell proliferation in the HER2-overexpressing cancer cell line NCI-N87 Kawai S 2012 Nov 01
  • PubChem
22145955 Differential expression of LeY and fucosyltransferase IV correlates with the receptivity of RL95‐2 and HEC‐1A human uterine epithelial cells Liu S 2012 May 01
  • PubChem
22593503 Expression of the tumor markers sialyl Lewis A, sialyl Lewis X, Lewis Y, Thomsen-Friedenreich antigen, galectin-1 and galectin-3 in human osteoblasts in vitro Tübel J 2012 May
  • PubChem
22172384 Combined-modality radioimmunotherapy: synergistic effect of paclitaxel and additive effect of bevacizumab Jang B 2012 May
  • PubChem
22416779 Recent Advances In Developing Synthetic Carbohydrate-Based Vaccines For Cancer Immunotherapies Hevey R 2012 Mar
  • PubChem
PubAnnotation
Displaying entries 1 - 5 of 10 in total
Title Authors Source Publication Date PubMed ID
Development of potent monoclonal antibody auristatin conjugates for cancer therapy.
  • Doronina SO
  • Toki BE
  • Torgov MY
  • Mendelsohn BA
  • Cerveny CG
  • Chace DF
  • DeBlanc RL
  • Gearing RP
  • Bovee TD
  • Siegall CB
  • Francisco JA
  • Wahl AF
  • Meyer DL
  • Senter PD
Nat Biotechnol 2003 Jul 12778055
The expression of free oligosaccharides in human seminal plasma.
  • Chalabi S
  • Easton RL
  • Patankar MS
  • Lattanzio FA
  • Morrison JC
  • Panico M
  • Morris HR
  • Dell A
  • Clark GF
J Biol Chem 2002 Sep 6 12063266
Phenotypic variation in molecular mimicry between Helicobacter pylori lipopolysaccharides and human gastric epithelial cell surface glycoforms. Acid-induced phase variation in Lewis(x) and Lewis(y) expression by H. Pylori lipopolysaccharides.
  • Moran AP
  • Knirel YA
  • Senchenkova SN
  • Widmalm G
  • Hynes SO
  • Jansson PE
J Biol Chem 2002 Feb 22 11741906
Pursuit of optimal carbohydrate-based anticancer vaccines: preparation of a multiantigenic unimolecular glycopeptide containing the Tn, MBr1, and Lewis(y) antigens.
  • Allen JR
  • Harris CR
  • Danishefsky SJ
J Am Chem Soc 2001 Mar 7 11456809
The fucosylated histo-blood group antigens H type 2 (blood group O, CD173) and Lewis Y (CD174) are expressed on CD34+ hematopoietic progenitors but absent on mature lymphocytes.
  • Cao Y
  • Merling A
  • Karsten U
  • Schwartz-Albiez R
Glycobiology 2001 Aug 11479278

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