G00059MO

Summary
GlyTouCan ID
G00059MO
IUPAC Condensed
Gal(a1-4)Gal(b1-4)Glc(b1-
Motifs
Gb3 Pk antigen globotriaosylceramide
Subsumption Level
Fully-defined saccharide
Monoisotopic Mass
504.17
GlyGen
ChEBI
PubChem Compound
PubChem Substance
GlycoShape
Displaying 1 entry
Archetype α β
G67710XV
G79094AA
G00059MO
3D Structures
GlycoNAVI
G00059MO
GlycoShape
G00059MO
GLYCAM
DGalpa1-4DGalpb1-4DGlcpb1-OH
Organisms
Taxonomic Hierarchy
GlycoGene Database (GGDB)
Displaying 1 entry
Gene Symbol Donor Acceptor Reducing terminal(Acceptor) Product Reducing terminal(Product) Reference
A4GALT UDP-Gal
G84224TW
Cer
G00059MO
Cer
Displaying all 2 entries
Gene Symbol Donor Acceptor Reducing terminal(Acceptor) Product Reducing terminal(Product) Reference
A4GALT UDP-Gal
G84224TW
Cer
G00059MO
Cer
B3GALNT1 UDP-GalNAc
G00059MO
Cer
G00061MO
Cer
Displaying all 5 entries
Gene Symbol Donor Acceptor Reducing terminal(Acceptor) Reference
B3GALT1 UDP-Gal
G00059MO
Cer
B3GALT2 UDP-Gal
G00059MO
Cer
B4GALT3 UDP-Gal
G00059MO
Cer
B3GALT4 UDP-Gal
G00059MO
Cer
B3GALNT2 UDP-GalNAc
G00059MO
Cer
GlycoEpitope
Epitope ID
EP0071
Epitope Name
Gb3
Sequence Descriptors
GlycoCT
RES
1b:b-dglc-HEX-1:5
2b:b-dgal-HEX-1:5
3b:a-dgal-HEX-1:5
LIN
1:1o(4+1)2d
2:2o(4+1)3d
WURCS
WURCS=2.0/3,3,2/[a2122h-1b_1-5][a2112h-1b_1-5][a2112h-1a_1-5]/1-2-3/a4-b1_b4-c1
Literature
Displaying entries 1 - 10 of 61 in total
PubMed ID Title First Author Publication Date Source
35248944 Synthesis of globotriose-modified peptides for the preparation of a colorimetric biosensor to detect Shiga toxins Kong Y 2022 Jun 01
  • PubChem
32255449 Biochemical characterisation of an α1,4 galactosyltransferase from Neisseria weaveri for the synthesis of α1,4-linked galactosides Huang K 2020 Apr 29
  • PubChem
32306329 Purification and Functional Characterization of the Effects on Cell Signaling of Mytilectin: A Novel β-Trefoil Lectin from Marine Mussels Fujii Y 2020
  • PubChem
31631323 Designer biocatalysts for direct incorporation of exogenous galactose into globotriose Long L 2019 Nov 12
  • PubChem
31466257 MytiLec-1 Shows Glycan-Dependent Toxicity against Brine Shrimp Artemia and Induces Apoptotic Death of Ehrlich Ascites Carcinoma Cells In Vivo Hasan I 2019 Aug 28
  • PubChem
30486373 Mutagenesis Studies and Structure-function Relationships for GalNAc/Gal-Specific Lectin from the Sea Mussel Crenomytilus grayanus Kovalchuk SN 2018 Nov 27
  • PubChem
29512997 Glycosylated Peptoid Nanosheets as a Multivalent Scaffold for Protein Recognition Battigelli A 2018 Mar 07
  • PubChem
30420327 Synthetic construction of sugar-amino acid hybrid polymers involving globotriaose or lactose and evaluation of their biological activities against Shiga toxins produced by Escherichia coli O157:H7 Matsuoka K 2018 Dec 01
  • PubChem
30504657 [Application of Lectin from Catfish Eggs to Cancer Therapy: A Fundamental Study] Sugawara S 2018
  • PubChem
28708979 Why human anti-Galα1–4Galβ1–4Glc natural antibodies do not recognize the trisaccharide on erythrocyte membrane? Molecular dynamics and immunochemical investigation Volynsky P 2017 Oct
  • PubChem
PubAnnotation
Displaying entries 6 - 10 of 10 in total
Title Authors Source Publication Date PubMed ID
A single point mutation in the gene encoding Gb3/CD77 synthase causes a rare inherited polyagglutination syndrome.
  • Suchanowska A
  • Kaczmarek R
  • Duk M
  • Lukasiewicz J
  • Smolarek D
  • Majorczyk E
  • Jaskiewicz E
  • Laskowska A
  • Wasniowska K
  • Grodecka M
  • Lisowska E
  • Czerwinski M
J Biol Chem 2012 Nov 2 22965229
Specific adsorption of functionalized colloids at the surface of living cells: a quantitative kinetic analysis of the receptor-mediated binding.
  • Poirier C
  • van Effenterre D
  • Delord B
  • Johannes L
  • Roux D
Biochim Biophys Acta 2008 Oct 18675781
Role of glycosphingolipid microdomains in CD4-dependent HIV-1 fusion.
  • Fantini J
  • Hammache D
  • Piéroni G
  • Yahi N
Glycoconj J 2000 Mar-Apr 11201791
Up-regulation of neutral glycosphingolipid synthesis upon long term inhibition of ceramide synthesis by fumonisin B1.
  • Meivar-Levy I
  • Futerman AH
J Biol Chem 1999 Feb 19 9988695
Anti-GM3-lactam monoclonal antibodies of the IgG type recognize natural GM3-ganglioside lactone but not GM3-ganglioside.
  • Ding K
  • Rosén A
  • Ray AK
  • Magnusson G
Glycoconj J 1992 Dec 1305422

About Release Notes Help Feedback

Click here to visit the beta site.


International Collaboration

GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01


Logo License Policies Site Map

Contact: support@glycosmos.org

This work is licensed under Creative Commons Attribution 4.0 International


GlyCosmos Portal v4.2.1

Last updated: April 7, 2025