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GlyTouCan
Glycan Structure Repository
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Glycoconjugate Repository
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Glycomics MS raw data Repository
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Glycomics MS Repository for glycan annotations from GlycoWorkbench
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Repository for lectin-assisted multimodality data
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G01614ZM
Summary
- GlyTouCan ID
-
G01614ZM
- IUPAC Condensed
- Neu5Ac(a2-3)Gal(b1-3)[Neu5Ac(a2-6)]GalNAc(a1-
- Motifs
- Di-sialyl T antigen
- Subsumption Level
- Fully-defined saccharide
- Monoisotopic Mass
- 965.33
G30110UW
G04267XF
3D Structures
- GlycoShape
- G01614ZM
- GLYCAM
- Neup5Aca2-3DGalpb1-3[Neup5Aca2-6]DGalpNAca1-OH
Organisms
| Organisms | Evidence |
|---|---|
| Mus musculus (house mouse) | |
| Friend murine leukemia virus | |
| Cricetulus griseus (Chinese hamster) | |
| Homo sapiens (human) | |
| Danio rerio (zebrafish) |
Taxonomic Hierarchy
root
cellular organisms [inference]
Eukaryota (eucaryotes) [inference]
GlycoGene Database (GGDB)
| Gene Symbol | Donor | Acceptor | Reducing terminal(Acceptor) | Product | Reducing terminal(Product) | Reference |
|---|---|---|---|---|---|---|
| ST6GALNAC4 | CMP-Neu5Ac |
G65562ZE
|
R |
G01614ZM
|
R | |
| ST6GALNAC1 | CMP-Neu5Ac |
G65562ZE
|
Ser/Thr |
G01614ZM
|
Ser/Thr | |
| ST6GALNAC3 | CMP-Neu5Ac |
G65562ZE
|
Ser/Thr |
G01614ZM
|
Ser/Thr | |
| ST6GALNAC2 | CMP-Neu5Ac |
G65562ZE
|
Ser/Thr |
G01614ZM
|
Ser/Thr | |
| ST6GALNAC4 | CMP-Neu5Ac |
G65562ZE
|
Ser/Thr |
G01614ZM
|
Ser/Thr |
| Gene Symbol | Donor | Acceptor | Reducing terminal(Acceptor) | Product | Reducing terminal(Product) | Reference |
|---|---|---|---|---|---|---|
| ST6GALNAC4 | CMP-Neu5Ac |
G65562ZE
|
R |
G01614ZM
|
R | |
| ST6GALNAC1 | CMP-Neu5Ac |
G65562ZE
|
Ser/Thr |
G01614ZM
|
Ser/Thr | |
| ST6GALNAC3 | CMP-Neu5Ac |
G65562ZE
|
Ser/Thr |
G01614ZM
|
Ser/Thr | |
| ST6GALNAC2 | CMP-Neu5Ac |
G65562ZE
|
Ser/Thr |
G01614ZM
|
Ser/Thr | |
| ST6GALNAC4 | CMP-Neu5Ac |
G65562ZE
|
Ser/Thr |
G01614ZM
|
Ser/Thr |
KEGG BRITE Database
Core Protein
| UniProt ID | Protein Name | Reference | Source |
|---|---|---|---|
| P02668 | Kappa-casein | ||
| P02724 | Glycophorin-A | ||
| P02727 | Glycophorin-A | ||
| P03395 | Envelope glycoprotein (Fragment) | ||
| P03415 | Membrane protein | ||
| P04275 | von Willebrand factor | ||
| P04278 | Sex hormone-binding globulin | ||
| P04921 | Glycophorin-C | ||
| P06028 | Glycophorin-B | ||
| P06867 | Plasminogen |
GlycoEpitope
- Epitope ID
- EP0023
- Epitope Name
- Disialyl T Antigen
GlycomeAtlas
Tissues in which this glycan is expressed are highlighted in yellow.
- Danio rerio
Literature
- Tissue
-
- brain
- gill
- heart
- intestine
- liver
- skin gland
- testis
- Reference
- Yamakawa N et al. Systems glycomics of adult zebrafish identifies organ-specific sialylation and glycosylation patterns. Nat Commun. 2018;9(1):4647. Published 2018 Nov 7. doi:10.1038/s41467-018-06950-3
- DOI
- 10.1038/s41467-018-06950-3
Localization sites organized by hierarchy by Uber-anatomy ontology (UBERON)
Sequence Descriptors
- GlycoCT
-
RES 1b:a-dgal-HEX-1:5 2s:n-acetyl 3b:b-dgal-HEX-1:5 4b:a-dgro-dgal-NON-2:6|1:a|2:keto|3:d 5s:n-acetyl 6b:a-dgro-dgal-NON-2:6|1:a|2:keto|3:d 7s:n-acetyl LIN 1:1d(2+1)2n 2:1o(3+1)3d 3:3o(3+2)4d 4:4d(5+1)5n 5:1o(6+2)6d 6:6d(5+1)7n
- WURCS
- WURCS=2.0/3,4,3/[a2112h-1a_1-5_2*NCC/3=O][a2112h-1b_1-5][Aad21122h-2a_2-6_5*NCC/3=O]/1-2-3-3/a3-b1_a6-d2_b3-c2
Literature
| PubMed ID | Title | First Author | Publication Date | Source |
|---|---|---|---|---|
| 34191522 | The O-Glycome of Human Nigrostriatal Tissue and Its Alteration in Parkinson's Disease | Wilkinson H | 2021 Aug 6 |
|
| 32841605 | Virus-Receptor Interactions of Glycosylated SARS-CoV-2 Spike and Human ACE2 Receptor | Zhao P | 2020 Oct 07 |
|
| 32921414 | Crystal structure of an anti-podoplanin antibody bound to a disialylated O-linked glycopeptide | Ogasawara S | 2020 Nov 26 |
|
| 32236654 | Colorectal cancer cell lines show striking diversity of their O-glycome reflecting the cellular differentiation phenotype | Madunic K | 2020 Mar 31 |
|
| 30405127 | Systems glycomics of adult zebrafish identifies organ-specific sialylation and glycosylation patterns | Yamakawa N | 2018 Nov 07 |
|
| 25187573 | The O-glycomap of Lubricin, a Novel Mucin Responsible for Joint Lubrication, Identified by Site-specific Glycopeptide Analysis | Ali L | 2014 Dec |
|
| 23001782 | Micro- and macroheterogeneity of N-glycosylation yields size and charge isoforms of human sex hormone binding globulin circulating in serum | Sumer-Bayraktar Z | 2012 Nov |
|
| 19609959 | Identification of blood group A/A-Leb/y and B/B-Leb/y active glycotopes co-expressed on the O-glycans isolated from two distinct human ovarian cyst fluids | Yu S | 2009 Jul |
|
| 17090649 | Variations in glycosylation of von Willebrand factor with O-linked sialylated T antigen are associated with its plasma levels | van Schooten CJ | 2006 Nov 07 |
|
| 16169874 | Molecular Cloning and Expression of Human ST6GalNAc III: Restricted Tissue Distribution and Substrate Specificity | Tsuchida A | 2005 Sep 01 |
|
PubAnnotation
