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Standards Ontologies Notations
Guidelines
MIRAGE
Sex hormone-binding globulin

Summary
UniProt ID
P04278
Gene Symbol
  • SHBG
Gene ID
6462
Organism
Homo sapiens (human)
GlycoProtDB
GPDB0011365
GlyConnect
GlyGen
P04278
PubChem
P04278
The Human Metabolome Database
HMDBP01623
RaftProt
P04278
Re-Glyco
P04278
Annotation
Keyword
  • 3D-structure
  • Alternative splicing
  • Direct protein sequencing
  • Disulfide bond
  • Glycoprotein
  • Reference proteome
  • Repeat
  • Secreted
  • Signal
  • Steroid-binding
Gene Ontology (GO)
Displaying all 2 entries
GO Term
extracellular exosome
extracellular region
Subcellular Location(GO Annotation)

Subcellular in which this glycoprotein is expressed are highlighted in blue.

Displaying all 2 entries
GO Term
androgen binding
steroid binding
Annotation information from UniProt.
Sequence
MESRGPLATSRLLLLLLLLLLRHTRQGWALRPVLPTQSAHDPPAVHLSNGPGQEPIAVMTFDLTKITKTSSSFEVRTWDPEGVIFYGDTNPKDDWFMLGLRDGRPEIQLHNHWAQLTVGAGPRLDDGRWHQVEVKMEGDSVLLEVDGEEVLRLRQVSGPLTSKRHPIMRIALGGLLFPASNLRLPLVPALDGCLRRDSWLDKQAEISASAPTSLRSCDVESNPGIFLPPGTQAEFNLRDIPQPHAEPWAFSLDLGLKQAAGSGHLLALGTPENPSWLSLHLQDQKVVLSSGSGPGLDLPLVLGLPLQLKLSMSRVVLSQGSKMKALALPPLGLAPLLNLWAKPQGRLFLGALPGEDSSTSFCLNGLWAQGQRLDVDQALNRSHEIWTHSCPQSPGNGTDASH
  • N : N-glycosylation Site
  • ___ : Potential Sequon
Glycosylation Sites
Displaying all 4 entries
Position Description PubMed ID GlyTouCan ID Source
36 O-linked (GalNAc...) threonine
380 N-linked (GlcNAc...) asparagine
396 N-linked (GlcNAc...) asparagine
Feature
  • ProtVista GlyGen : Glycosylation Site from GlyGen
  • ProtVista UniProt : Glycosylation Site from UniProt
Disease
Displaying all 2 entries
DO ID Disease Name Source
DOID:1380 endometrial cancer
DOID:9352 type 2 diabetes mellitus
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International Collaboration

GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: August 4, 2025