G57321FI

Summary
GlyTouCan ID
G57321FI
IUPAC Condensed
GalNAc(a1-
Motifs
Tn antigen
GlyConnect structure
GlyGen
ChEBI
PubChem Compound
PubChem Substance
The Human Metabolome Database
3D Structures
GlycoNAVI
G57321FI
GLYCAM
DGalpNAca1-OH
GlycoShape
Organisms
Taxonomic Hierarchy
GlycoGene Database (GGDB)
Displaying all 4 entries
Gene Symbol Donor Acceptor Reducing terminal(Acceptor) Product Reducing terminal(Product) Reference
C1GALT1 (not applicable)
G57321FI
Ser/Thr
G00031MO
Ser/Thr
ST6GALNAC1 CMP-Neu5Ac
G57321FI
Ser/Thr
G36123IU
Ser/Thr
ST6GALNAC1 CMP-Neu5Ac
G57321FI
O-glycan Synthesis
G36123IU
O-glycan Synthesis
B3GNT6 UDP-GlcNAc
G57321FI
[alpha]-pNP
G00035MO
[alpha]-pNP
Displaying entries 1 - 5 of 9 in total
Gene Symbol Donor Acceptor Reducing terminal(Acceptor) Product Reducing terminal(Product) Reference
C1GALT1 (not applicable)
G57321FI
Ser/Thr
G00031MO
Ser/Thr
ST6GALNAC1 CMP-Neu5Ac
G57321FI
Ser/Thr
G36123IU
Ser/Thr
ST6GALNAC4 CMP-Neu5Ac
G57321FI
benzyl
G36123IU
benzyl
ST6GALNAC1 CMP-Neu5Ac
G57321FI
O-glycan Synthesis
G36123IU
O-glycan Synthesis
ST6GALNAC1 CMP-Neu5Ac
G57321FI
[Ala-Thr(*)-Ala]2-7
G36123IU
[Ala-Thr(*)-Ala]2-7
Displaying entries 11 - 15 of 35 in total
Gene Symbol Donor Acceptor Reducing terminal(Acceptor) Reference
B3GALT2 UDP-Gal
G57321FI
benzyl
B3GALT6 UDP-Gal
G57321FI
naphothalenemethanol, para-nitrophenol
B3GALT1 UDP-Gal
G57321FI
benzyl
B3GALT6 UDP-Gal
G57321FI
Benzyl, para-nitrophenol
B3GNT2 UDP-Gal
G57321FI
[alpha]1-OBn
GlycoEpitope
Epitope ID
EP0021
Pathway
Displaying entries 1 - 10 of 57 in total
Pathway Name Organism
E.coli O101 Escherichia coli
E.coli O103 Escherichia coli
E.coli O107 Escherichia coli
E.coli O112ab Escherichia coli
E.coli O112ac Escherichia coli
E.coli O116 Escherichia coli
E.coli O117 Escherichia coli
E.coli O125ab Escherichia coli
E.coli O127 Escherichia coli
E.coli O128ab-H27 Escherichia coli
Sequence Descriptors
GlycoCT
RES
1b:a-dgal-HEX-1:5
2s:n-acetyl
LIN
1:1d(2+1)2n
WURCS
WURCS=2.0/1,1,0/[a2112h-1a_1-5_2*NCC/3=O]/1/
Literature
Displaying entries 311 - 320 of 2052 in total
PubMed ID Title First Author Publication Date Source
28087069 Safety, tolerability, and antiviral effect of RG-101 in patients with chronic hepatitis C: a phase 1B, double-blind, randomised controlled trial van der Ree MH 2017 Feb 18
  • PubChem
28158620 Characterizing the effect of GalNAc and phosphorothioate backbone on binding of antisense oligonucleotides to the asialoglycoprotein receptor Schmidt K 2017 Feb 03
  • PubChem
27973758 Structural analysis and unique molecular recognition properties of a Bauhinia forficata lectin that inhibits cancer cell growth Lubkowski J 2017 Feb
  • PubChem
27984144 Lectin from seeds of a Brazilian lima bean variety (Phaseolus lunatus L. var. cascavel) presents antioxidant, antitumour and gastroprotective activities e Lacerda RR 2017 Feb
  • PubChem
29046357 Structural and thermodynamic analyses reveal critical features of glycopeptide recognition by the human PILRα immune cell receptor Furukawa A 2017 Dec 22
  • PubChem
29166012 The Use of Fluoroproline in MUC1 Antigen Enables Efficient Detection of Antibodies in Patients with Prostate Cancer Somovilla VJ 2017 Dec 12
  • PubChem
29208955 The interdomain flexible linker of the polypeptide GalNAc transferases dictates their long-range glycosylation preferences de las Rivas M 2017 Dec 05
  • PubChem
29193962 Cell Penetrating Polymers Containing Guanidinium Trigger Apoptosis in Human Hepatocellular Carcinoma Cells unless Conjugated to a Targeting N-Acetyl-Galactosamine Block Tan Z 2017 Dec 01
  • PubChem
28526733 Discovery and Optimization of HKT288, a Cadherin-6–Targeting ADC for the Treatment of Ovarian and Renal Cancers Bialucha CU 2017 Aug 31
  • PubChem
28809818 Synthesis of 5′-GalNAc-Conjugated Oligonucleotides: A Comparison of Solid and Solution-Phase Conjugation Strategies Cedillo I 2017 Aug 15
  • PubChem
PubAnnotation
Displaying entries 1 - 5 of 9 in total
Title Authors Source Publication Date PubMed ID
The Quest for Anticancer Vaccines: Deciphering the Fine-Epitope Specificity of Cancer-Related Monoclonal Antibodies by Combining Microarray Screening and Saturation Transfer Difference NMR.
  • Coelho H
  • Matsushita T
  • Artigas G
  • Hinou H
  • Cañada FJ
  • Lo-Man R
  • Leclerc C
  • Cabrita EJ
  • Jiménez-Barbero J
  • Nishimura S
  • Garcia-Martín F
  • Marcelo F
J Am Chem Soc 2015 Oct 7 26366611
Single molecule study of heterotypic interactions between mucins possessing the Tn cancer antigen.
  • Haugstad KE
  • Stokke BT
  • Brewer CF
  • Gerken TA
  • Sletmoen M
Glycobiology 2015 May 25527429
Loss of Core 1-derived O-Glycans Decreases Breast Cancer Development in Mice.
  • Song K
  • Herzog BH
  • Fu J
  • Sheng M
  • Bergstrom K
  • McDaniel JM
  • Kondo Y
  • McGee S
  • Cai X
  • Li P
  • Chen H
  • Xia L
J Biol Chem 2015 Aug 14 26124270
Identification of distinct glycoforms of IgA1 in plasma from patients with immunoglobulin A (IgA) nephropathy and healthy individuals.
  • Lehoux S
  • Mi R
  • Aryal RP
  • Wang Y
  • Schjoldager KT
  • Clausen H
  • van Die I
  • Han Y
  • Chapman AB
  • Cummings RD
  • Ju T
Mol Cell Proteomics 2014 Nov 25071157
Human T cell activation results in extracellular signal-regulated kinase (ERK)-calcineurin-dependent exposure of Tn antigen on the cell surface and binding of the macrophage galactose-type lectin (MGL).
  • van Vliet SJ
  • Vuist IM
  • Lenos K
  • Tefsen B
  • Kalay H
  • García-Vallejo JJ
  • van Kooyk Y
J Biol Chem 2013 Sep 20 23918927

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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01


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