G00035MO

Summary
GlyTouCan ID
G00035MO
IUPAC Condensed
GlcNAc(b1-3)GalNAc(a1-
Motifs
O-Glycan core 3
Subsumption Level
Fully-defined saccharide
Monoisotopic Mass
424.17
GlyConnect structure
GlyGen
ChEBI
PubChem Compound
PubChem Substance
CarbBank
3D Structures
GlycoShape
G00035MO
Displaying 1 entry
Archetype α β
G00036MO
G00035MO
G75113PZ
GlycoGene Database (GGDB)
Displaying all 3 entries
Gene Symbol Donor Acceptor Reducing terminal(Acceptor) Product Reducing terminal(Product) Reference
B3GALT5 UDP-Gal
G00035MO
a-OpNp
G11647UD
a-OpNp
B3GNT6 UDP-GlcNAc
G57321FI
[alpha]-pNP
G00035MO
[alpha]-pNP
GCNT3 UDP-GlcNAc
G00035MO
Ser/Thr
G00037MO
Ser/Thr
Displaying entries 1 - 5 of 14 in total
Gene Symbol Donor Acceptor Reducing terminal(Acceptor) Product Reducing terminal(Product) Reference
ST6GALNAC1 CMP-Neu5Ac
G00035MO
O-glycan Synthesis
G63334FZ
O-glycan Synthesis
B4GALT4 UDP-Gal
G00035MO
p-Nitrophenyl
G32723SL
p-Nitrophenyl
B3GALT5 UDP-Gal
G00035MO
a-OpNp
G11647UD
a-OpNp
B4GALT1 UDP-Gal
G00035MO
O-glycan Synthesis
G32723SL
O-glycan Synthesis
B3GALT5 UDP-Gal
G00035MO
O-glycan Synthesis
G11647UD
O-glycan Synthesis
Displaying entries 1 - 5 of 8 in total
Gene Symbol Donor Acceptor Reducing terminal(Acceptor) Reference
C1GALT1 UDP-Gal
G00035MO
O-glycan Synthesis
B3GNT7 UDP-GlcNAc
G00035MO
core 3-pNp
A4GNT UDP-GlcNAc
G00035MO
pNP
B3GNT8 UDP-GlcNAc
G00035MO
core 3-pNp
GCNT4 UDP-GlcNAc
G00035MO
[alpha]-1-p-nitrophenyl
KEGG BRITE Database
KEGG ID
Enzyme
Reactions
Displaying all 2 entries
KEGG Reaction Enzyme Acceptor Product
R05915
R05909
Core Protein
Displaying 1 entry
UniProt ID Protein Name Reference Source
Q02817 Mucin-2
Sequence Descriptors
GlycoCT
RES
1b:a-dgal-HEX-1:5
2s:n-acetyl
3b:b-dglc-HEX-1:5
4s:n-acetyl
LIN
1:1d(2+1)2n
2:1o(3+1)3d
3:3d(2+1)4n
WURCS
WURCS=2.0/2,2,1/[a2112h-1a_1-5_2*NCC/3=O][a2122h-1b_1-5_2*NCC/3=O]/1-2/a3-b1
Literature
Displaying entries 1 - 10 of 24 in total
PubMed ID Title First Author Publication Date Source
34191522 The O-Glycome of Human Nigrostriatal Tissue and Its Alteration in Parkinson's Disease Wilkinson H 2021 Aug 6
  • GlyGen
19422833 N-Acetylglucosamine Recognition by a Family 32 Carbohydrate-Binding Module from Clostridium perfringens NagH Ficko-Blean E 2009 Jul 10
  • PubChem
15620693 A novel β1,3‐N‐acetylglucosaminyltransferase (β3Gn‐T8), which synthesizes poly‐N‐acetyllactosamine, is dramatically upregulated in colon cancer Ishida H 2004 Nov 28
  • PubChem
15044014 Molecular cloning and characterization of β1,4‐N‐acetylgalactosaminyltransferases IV synthesizing N,N′‐diacetyllactosediamine1 Gotoh M 2004 Mar 05
  • PubChem
14724282 A novel human beta1,3-N-acetylgalactosaminyltransferase that synthesizes a unique carbohydrate structure, GalNAcbeta1-3GlcNAc Hiruma T 2004 Apr 02
  • PubChem
12966086 Molecular cloning and characterization of a novel human beta 1,4-N-acetylgalactosaminyltransferase, beta 4GalNAc-T3, responsible for the synthesis of N,N'-diacetyllactosediamine, galNAc beta 1-4GlcNAc Sato T 2003 Nov 28
  • PubChem
11821425 Molecular cloning and characterization of a novel UDP-GlcNAc:GalNAc-peptide beta1,3-N-acetylglucosaminyltransferase (beta 3Gn-T6), an enzyme synthesizing the core 3 structure of O-glycans Iwai T 2002 Apr 12
  • PubChem
10753916 Control of O-glycan branch formation. Molecular cloning and characterization of a novel thymus-associated core 2 beta1, 6-n-acetylglucosaminyltransferase Schwientek T 2000 Apr 14
  • PubChem
10406968 Molecular cloning of a human UDP-galactose:GlcNAcbeta1,3GalNAc beta1, 3 galactosyltransferase gene encoding an O-linked core3-elongation enzyme Zhou D 1999 Jul 15
  • PubChem
9915862 Molecular cloning and expression of a novel beta-1, 6-N-acetylglucosaminyltransferase that forms core 2, core 4, and I branches Yeh JC 1999 Jan 29
  • PubChem
PubAnnotation
Displaying entries 1 - 5 of 9 in total
Title Authors Source Publication Date PubMed ID
Glycosyltransferases involved in type 1 chain and Lewis antigen biosynthesis exhibit glycan and core chain specificity.
  • Holgersson J
  • Löfling J
Glycobiology 2006 Jul 16484342
Elucidation of binding specificity of Jacalin toward O-glycosylated peptides: quantitative analysis by frontal affinity chromatography.
  • Tachibana K
  • Nakamura S
  • Wang H
  • Iwasaki H
  • Tachibana K
  • Maebara K
  • Cheng L
  • Hirabayashi J
  • Narimatsu H
Glycobiology 2006 Jan 16177266
Purification and cDNA cloning of UDP-GlcNAc:GlcNAcbeta1-3Galbeta1-4Glc(NAc)-R [GlcNAc to Gal]beta1,6N-acetylglucosaminyltransferase from rat small intestine: a major carrier of dIGnT activity in rat small intestine.
  • Korekane H
  • Taguchi T
  • Sakamoto Y
  • Honke K
  • Dohmae N
  • Salminen H
  • Toivonen S
  • Helin J
  • Takio K
  • Renkonen O
  • Taniguchi N
Glycobiology 2003 May 12626393
Specificities of N-acetylglucosamine-6-O-sulfotransferases in relation to L-selectin ligand synthesis and tumor-associated enzyme expression.
  • Uchimura K
  • El-Fasakhany FM
  • Hori M
  • Hemmerich S
  • Blink SE
  • Kansas GS
  • Kanamori A
  • Kumamoto K
  • Kannagi R
  • Muramatsu T
J Biol Chem 2002 Feb 8 11726653
Molecular cloning and characterization of a novel UDP-GlcNAc:GalNAc-peptide beta1,3-N-acetylglucosaminyltransferase (beta 3Gn-T6), an enzyme synthesizing the core 3 structure of O-glycans.
  • Iwai T
  • Inaba N
  • Naundorf A
  • Zhang Y
  • Gotoh M
  • Iwasaki H
  • Kudo T
  • Togayachi A
  • Ishizuka Y
  • Nakanishi H
  • Narimatsu H
J Biol Chem 2002 Apr 12 11821425

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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01


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