GlyCosmos Portal

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Organisms	Evidence
Ovis aries (sheep)	GlyTouCan(glycome-db)
Cricetulus griseus (Chinese hamster)	GlyTouCan(glycome-db)
Mus musculus (house mouse)	GlyConnectStructure GlyTouCan(glycome-db) GlycoEpitope
Bos taurus (domestic cattle)	GlyTouCan(glycome-db)
Escherichia coli	GlyTouCan(bcsdb)

Taxonomic Hierarchy

root

cellular organisms [inference]

Bacteria (eubacteria) [inference]

Pseudomonadota [inference]

Gammaproteobacteria [inference]

Enterobacterales [inference]

Enterobacteriaceae [inference]

Escherichia [inference]

Escherichia coli

Pseudomonadales [inference]

Pseudomonadaceae [inference]

Pseudomonas [inference]

Pseudomonas aeruginosa group [inference]

Pseudomonas aeruginosa

Eukaryota (eucaryotes) [inference]

Opisthokonta [inference]

Metazoa (metazoans) [inference]

Eumetazoa [inference]

Bilateria [inference]

Deuterostomia [inference]

Chordata (chordates) [inference]

Craniata [inference]

Vertebrata (vertebrates) [inference]

Gnathostomata (jawed vertebrates) [inference]

Teleostomi [inference]

Euteleostomi (bony vertebrates) [inference]

Sarcopterygii [inference]

Dipnotetrapodomorpha [inference]

Tetrapoda (tetrapods) [inference]

Amniota (amniotes) [inference]

Mammalia (mammals) [inference]

Theria [inference]

Eutheria (placentals) [inference]

Boreoeutheria [inference]

Euarchontoglires [inference]

Glires (Rodents and rabbits) [inference]

Rodentia (rodent) [inference]

Myomorpha (mice and others) [inference]

Muroidea [inference]

Muridae [inference]

Murinae [inference]

Mus (mice) [inference]

Mus [inference]

Mus musculus (house mouse)

Rattus [inference]

Rattus norvegicus (Norway rat)

Cricetidae [inference]

Cricetinae (hamsters) [inference]

Cricetulus [inference]

Cricetulus griseus (Chinese hamster)

Lagomorpha [inference]

Leporidae (rabbits and hares) [inference]

Oryctolagus [inference]

Oryctolagus cuniculus (rabbit)

Primates [inference]

Haplorrhini [inference]

Simiiformes [inference]

Catarrhini [inference]

Hominoidea (apes) [inference]

Hominidae (great apes) [inference]

Homininae [inference]

Homo [inference]

Homo sapiens (human)

Cercopithecoidea [inference]

Cercopithecidae (Old World monkeys) [inference]

Cercopithecinae [inference]

Chlorocebus [inference]

Chlorocebus aethiops (grivet)

Macaca (macaques) [inference]

Macaca mulatta (Rhesus monkey)

Laurasiatheria [inference]

Artiodactyla (even-toed ungulates & whales) [inference]

Ruminantia [inference]

Pecora [inference]

Bovidae [inference]

Bovinae [inference]

Bos (cattle) [inference]

Bos taurus (domestic cattle)

Caprinae [inference]

Ovis [inference]

Ovis aries (sheep)

Protostomia [inference]

Ecdysozoa [inference]

Panarthropoda [inference]

Arthropoda (arthropods) [inference]

Mandibulata [inference]

Pancrustacea [inference]

Crustacea (crustaceans) [inference]

Multicrustacea [inference]

Malacostraca [inference]

Eumalacostraca [inference]

Peracarida [inference]

Isopoda (pill bugs, wood lice and sea slaters) [inference]

Oniscidea (pillbugs) [inference]

Crinocheta [inference]

Armadillidae [inference]

Armadillo

Hexapoda (hexapods) [inference]

Insecta (insects) [inference]

Dicondylia [inference]

Pterygota (winged insects) [inference]

Neoptera [inference]

Endopterygota [inference]

Diptera (flies) [inference]

Brachycera [inference]

Muscomorpha [inference]

Eremoneura [inference]

Cyclorrhapha [inference]

Schizophora [inference]

Acalyptratae [inference]

Ephydroidea [inference]

Drosophilidae (pomace flies) [inference]

Drosophilinae [inference]

Drosophilini [inference]

Drosophila (fruit flies) [inference]

Sophophora [inference]

melanogaster group [inference]

melanogaster subgroup [inference]

Drosophila melanogaster (fruit fly)

Calyptratae [inference]

Oestroidea [inference]

Calliphoridae (blowflies) [inference]

Chrysomyinae [inference]

Phormini [inference]

Protophormia [inference]

Protophormia terraenovae (northern blowfly)

Nematoda (roundworms) [inference]

Chromadorea [inference]

Rhabditida [inference]

Rhabditina [inference]

Rhabditomorpha [inference]

Strongyloidea (lungworms) [inference]

Heligmosomidae [inference]

Nippostrongylus [inference]

Nippostrongylus brasiliensis

Rhabditoidea [inference]

Rhabditidae [inference]

Peloderinae [inference]

Caenorhabditis [inference]

Caenorhabditis elegans

Spirurina [inference]

Ascaridomorpha [inference]

Ascaridoidea [inference]

Toxocaridae [inference]

Toxocara [inference]

Toxocara canis (dog roundworm)

Spiralia [inference]

Lophotrochozoa [inference]

Platyhelminthes (flatworms) [inference]

Cestoda (tapeworms) [inference]

Eucestoda [inference]

Cyclophyllidea [inference]

Taeniidae [inference]

Echinococcus [inference]

Echinococcus granulosus group [inference]

Echinococcus granulosus

Taenia [inference]

Taenia hydatigena

Mesocestoididae [inference]

Mesocestoides [inference]

Trematoda [inference]

Digenea (flukes) [inference]

Plagiorchiida [inference]

Echinostomata [inference]

Echinostomatoidea [inference]

Fasciolidae [inference]

Fasciola [inference]

Fasciola hepatica (liver fluke)

Fungi [inference]

Dikarya [inference]

Ascomycota (ascomycetes) [inference]

saccharomyceta [inference]

Saccharomycotina (true yeasts) [inference]

Saccharomycetes [inference]

Saccharomycetales [inference]

Saccharomycetaceae [inference]

Saccharomyces [inference]

Saccharomyces cerevisiae (brewer's yeast)

Viruses [inference]

Riboviria [inference]

Pararnavirae [inference]

Artverviricota [inference]

Revtraviricetes [inference]

Ortervirales [inference]

Retroviridae [inference]

Orthoretrovirinae [inference]

Lentivirus [inference]

Primate lentivirus group [inference]

unclassified Primate lentivirus group [inference]

Human immunodeficiency virus

Human immunodeficiency virus 1

Orthornavirae [inference]

Pisuviricota [inference]

Pisoniviricetes [inference]

Nidovirales [inference]

Cornidovirineae [inference]

Coronaviridae [inference]

Orthocoronavirinae [inference]

Betacoronavirus [inference]

Sarbecovirus [inference]

Severe acute respiratory syndrome-related coronavirus [inference]

Severe acute respiratory syndrome coronavirus 2

GlycoGene Database (GGDB)

Displaying **all 4** entries
Gene Symbol	Donor	Acceptor	Reducing terminal(Acceptor)	Product	Reducing terminal(Product)	Reference
C1GALT1	(not applicable)	G57321FI	Ser/Thr	G00031MO	Ser/Thr	11677243
ST6GALNAC1	CMP-Neu5Ac	G57321FI	Ser/Thr	G36123IU	Ser/Thr	10536037
ST6GALNAC1	CMP-Neu5Ac	G57321FI	O-glycan Synthesis	G36123IU	O-glycan Synthesis
B3GNT6	UDP-GlcNAc	G57321FI	[alpha]-pNP	G00035MO	[alpha]-pNP	11821425

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Gene Symbol	Donor	Acceptor	Reducing terminal(Acceptor)	Product	Reducing terminal(Product)	Reference
C1GALT1	(not applicable)	G57321FI	Ser/Thr	G00031MO	Ser/Thr	11677243
ST6GALNAC1	CMP-Neu5Ac	G57321FI	Ser/Thr	G36123IU	Ser/Thr	10536037
ST6GALNAC4	CMP-Neu5Ac	G57321FI	benzyl	G36123IU	benzyl	11062056
ST6GALNAC1	CMP-Neu5Ac	G57321FI	O-glycan Synthesis	G36123IU	O-glycan Synthesis
ST6GALNAC1	CMP-Neu5Ac	G57321FI	[Ala-Thr(*)-Ala]2-7	G36123IU	[Ala-Thr(*)-Ala]2-7	10536037

Displaying entries **11 - 15** of 35 in total

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Gene Symbol	Donor	Acceptor	Reducing terminal(Acceptor)	Reference
B3GALT2	UDP-Gal	G57321FI	benzyl	9417100
B3GALT6	UDP-Gal	G57321FI	naphothalenemethanol, para-nitrophenol	11551958
B3GALT1	UDP-Gal	G57321FI	benzyl	9417100
B3GALT6	UDP-Gal	G57321FI	Benzyl, para-nitrophenol	11551958
B3GNT2	UDP-Gal	G57321FI	[alpha]1-OBn	9892646

KEGG BRITE Database

KEGG ID

G00023

Enzyme

Reactions

Displaying **all 4** entries
KEGG Reaction	Enzyme	Acceptor	Product
R05909	2.4.1.147	G57321FI	G00035MO
R05908	2.4.1.122	G57321FI	G00031MO
R05911	2.4.3.3	G57321FI	G36123IU
R05910	2.4.1.102 2.4.1.148	G57321FI	G00041MO

Core Protein

Displaying entries **1 - 10** of **819** in total

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UniProt ID	Protein Name	Reference	Source
A1A5C7	Solute carrier family 22 member 23	23584533	GlyGen
A1L4H1	Soluble scavenger receptor cysteine-rich domain-containing protein SSC5D	23584533	GlyGen
A6NH11	Glycolipid transfer protein domain-containing protein 2	23584533	GlyGen
A6NLU5	V-set and transmembrane domain-containing protein 2B	23584533	GlyGen
C9J069	Apical junction component 1 homolog	23584533 25813380	GlyGen
C9JH25	Proline-rich transmembrane protein 4	23584533	GlyGen
D9N008	Epiglycanin	1125949 115878	GlyConnect
O00151	PDZ and LIM domain protein 1	23584533	GlyGen
O00220	Tumor necrosis factor receptor superfamily member 10A	23584533 25813380	GlyGen
O00238	Bone morphogenetic protein receptor type-1B	23584533	GlyGen

GlycoEpitope

Epitope ID: EP0021

Pathway

Displaying entries **1 - 10** of 57 in total

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Pathway Name	Organism
E.coli O101	Escherichia coli
E.coli O103	Escherichia coli
E.coli O107	Escherichia coli
E.coli O112ab	Escherichia coli
E.coli O112ac	Escherichia coli
E.coli O116	Escherichia coli
E.coli O117	Escherichia coli
E.coli O125ab	Escherichia coli
E.coli O127	Escherichia coli
E.coli O128ab-H27	Escherichia coli

Sequence Descriptors

GlycoCT

RES
1b:a-dgal-HEX-1:5
2s:n-acetyl
LIN
1:1d(2+1)2n

WURCS

WURCS=2.0/1,1,0/[a2112h-1a_1-5_2*NCC/3=O]/1/

Literature

Displaying entries **841 - 850** of **2052** in total

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PubMed ID	Title	First Author	Publication Date	Source
12529355	A Single Point Mutation Reverses the Donor Specificity of Human Blood Group B-synthesizing Galactosyltransferase	Marcus SL	2003 Apr 04	PubChem
12538583	Benzyl-N-acetyl-alpha-D-galactosaminide induces a storage disease-like phenotype by perturbing the endocytic pathway	Ulloa F	2003 Apr 04	PubChem
12672520	Identification of Entamoeba histolytica thiol-specific antioxidant as a GalNAc lectin-associated protein	Hughes MA	2003 Apr 03	PubChem
12672699	Aberrant O-glycosylation inhibits stable expression of dysadherin, a carcinoma-associated antigen, and facilitates cell-cell adhesion	Tsuiji H	2003 Apr 02	PubChem
12653629	Glycoprotein hormone GalNAc-4-sulphotransferase	Baenziger JU	2003 Apr 01	PubChem
12630904	Clostridium perfringensα ‐N ‐acetylgalactosaminidase blood group A2‐degrading activity	Hsieh H	2003 Apr	PubChem
14643765	Extracellular carbohydrate-signal triggering camp-dependent protein kinase-dependent neuronal actin-reorganization	Chen N	2003	PubChem
12235358	One O-linked sugar can affect the coil-to-beta structural transition of the prion peptide	Chen PY	2002 Sep 16	PubChem
12423754	Inhibition ofEscherichia coliheat-labile enterotoxin by neoglycoprotein and anti-lectin antibodies which mimic GM1 receptor	Menezes CA	2002 Oct 29	PubChem
12163485	Enzymatic Synthesis of Chondroitin with a Novel Chondroitin Sulfate N-Acetylgalactosaminyltransferase That Transfers N-Acetylgalactosamine to Glucuronic Acid in Initiation and Elongation of Chondroitin Sulfate Synthesis	Gotoh M	2002 Oct 11	PubChem

PubAnnotation

Displaying entries **1 - 5** of 9 in total

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Title	Authors	Source	Publication Date	PubMed ID
The Quest for Anticancer Vaccines: Deciphering the Fine-Epitope Specificity of Cancer-Related Monoclonal Antibodies by Combining Microarray Screening and Saturation Transfer Difference NMR.	Coelho H Matsushita T Artigas G Hinou H Cañada FJ Lo-Man R Leclerc C Cabrita EJ Jiménez-Barbero J Nishimura S Garcia-Martín F Marcelo F	J Am Chem Soc	2015 Oct 7	26366611
Single molecule study of heterotypic interactions between mucins possessing the Tn cancer antigen.	Haugstad KE Stokke BT Brewer CF Gerken TA Sletmoen M	Glycobiology	2015 May	25527429
Loss of Core 1-derived O-Glycans Decreases Breast Cancer Development in Mice.	Song K Herzog BH Fu J Sheng M Bergstrom K McDaniel JM Kondo Y McGee S Cai X Li P Chen H Xia L	J Biol Chem	2015 Aug 14	26124270
Identification of distinct glycoforms of IgA1 in plasma from patients with immunoglobulin A (IgA) nephropathy and healthy individuals.	Lehoux S Mi R Aryal RP Wang Y Schjoldager KT Clausen H van Die I Han Y Chapman AB Cummings RD Ju T	Mol Cell Proteomics	2014 Nov	25071157
Human T cell activation results in extracellular signal-regulated kinase (ERK)-calcineurin-dependent exposure of Tn antigen on the cell surface and binding of the macrophage galactose-type lectin (MGL).	van Vliet SJ Vuist IM Lenos K Tefsen B Kalay H García-Vallejo JJ van Kooyk Y	J Biol Chem	2013 Sep 20	23918927

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

All Resources

Other Information

Tools

Search Tools

Guidelines

Summary

External Links

KEGG BRITE Database

GlycoEpitope

Sequence Descriptors

International Collaboration

Acknowledgements