G57321FI

Summary
GlyTouCan ID
G57321FI
IUPAC Condensed
GalNAc(a1-
Motifs
Tn antigen
GlyConnect structure
GlyGen
ChEBI
PubChem Compound
PubChem Substance
The Human Metabolome Database
3D Structures
GlycoNAVI
G57321FI
GLYCAM
DGalpNAca1-OH
GlycoShape
Organisms
Taxonomic Hierarchy
GlycoGene Database (GGDB)
Displaying all 4 entries
Gene Symbol Donor Acceptor Reducing terminal(Acceptor) Product Reducing terminal(Product) Reference
C1GALT1 (not applicable)
G57321FI
Ser/Thr
G00031MO
Ser/Thr
ST6GALNAC1 CMP-Neu5Ac
G57321FI
Ser/Thr
G36123IU
Ser/Thr
ST6GALNAC1 CMP-Neu5Ac
G57321FI
O-glycan Synthesis
G36123IU
O-glycan Synthesis
B3GNT6 UDP-GlcNAc
G57321FI
[alpha]-pNP
G00035MO
[alpha]-pNP
Displaying entries 1 - 5 of 9 in total
Gene Symbol Donor Acceptor Reducing terminal(Acceptor) Product Reducing terminal(Product) Reference
C1GALT1 (not applicable)
G57321FI
Ser/Thr
G00031MO
Ser/Thr
ST6GALNAC1 CMP-Neu5Ac
G57321FI
Ser/Thr
G36123IU
Ser/Thr
ST6GALNAC4 CMP-Neu5Ac
G57321FI
benzyl
G36123IU
benzyl
ST6GALNAC1 CMP-Neu5Ac
G57321FI
O-glycan Synthesis
G36123IU
O-glycan Synthesis
ST6GALNAC1 CMP-Neu5Ac
G57321FI
[Ala-Thr(*)-Ala]2-7
G36123IU
[Ala-Thr(*)-Ala]2-7
Displaying entries 16 - 20 of 35 in total
Gene Symbol Donor Acceptor Reducing terminal(Acceptor) Reference
B4GALT3 UDP-Gal
G57321FI
Benzyl-[alpha]
B4GALT4 UDP-Gal
G57321FI
[alpha]-1-Benzyl
B4GALNT4 UDP-GalNAc
G57321FI
[alpha]-Bz
B3GALNT2 UDP-GalNAc
G57321FI
[alpha]-Bz
B3GALNT2 UDP-GalNAc
G57321FI
[beta]-pNP
GlycoEpitope
Epitope ID
EP0021
Pathway
Displaying entries 1 - 10 of 57 in total
Pathway Name Organism
E.coli O101 Escherichia coli
E.coli O103 Escherichia coli
E.coli O107 Escherichia coli
E.coli O112ab Escherichia coli
E.coli O112ac Escherichia coli
E.coli O116 Escherichia coli
E.coli O117 Escherichia coli
E.coli O125ab Escherichia coli
E.coli O127 Escherichia coli
E.coli O128ab-H27 Escherichia coli
Sequence Descriptors
GlycoCT
RES
1b:a-dgal-HEX-1:5
2s:n-acetyl
LIN
1:1d(2+1)2n
WURCS
WURCS=2.0/1,1,0/[a2112h-1a_1-5_2*NCC/3=O]/1/
Literature
Displaying entries 881 - 890 of 2052 in total
PubMed ID Title First Author Publication Date Source
11886841 Purification, characterization, and cDNA cloning of alpha-N-acetylgalactosamine-specific lectin from starfish, Asterina pectinifera Kakiuchi M 2002 Feb 01
  • PubChem
11936499 Lectin-binding by sporozoites of Eimeria tenella Fuller AL 2002 Feb
  • PubChem
12531524 Definition of pre- and postsynaptic forms of the CT carbohydrate antigen at the neuromuscular junction: ubiquitous expression of the CT antigens and the CT GalNAc transferase in mouse tissues Hoyte K 2002 Dec 30
  • PubChem
12379325 The epitope recognized by the unique anti-MUC1 monoclonal antibody MY.1E12 involves sialyl alpha 2-3galactosyl beta 1-3N-acetylgalactosaminide linked to a distinct threonine residue in the MUC1 tandem repeat Takeuchi H 2002 Dec 15
  • PubChem
12466406 N-Acetyl-d-galactosamine specific lectin of Eikenella corrodens induces intercellular adhesion molecule-1 (ICAM-1) production by human oral epithelial cells Yamada M 2002 Dec 01
  • PubChem
12630314 Presence and cellular distribution of soybean agglutinin-binding epitopes in two strains of Bacillus subtilis Stoitsova SR 2002 Dec
  • PubChem
12473113 O-GalNAc incorporation into a cluster acceptor site of three consecutive threonines. Distinct specificity of GalNAc-transferase isoforms Takeuchi H 2002 Dec
  • PubChem
12224923 First Thermally Responsive Supramolecular Polymer Based on Glycosylated Amino Acid Kiyonaka S 2002 Aug 23
  • PubChem
12146959 Effect of glycosylation on MUC1 humoral immune recognition: NMR studies of MUC1 glycopeptide-antibody interactions Grinstead JS 2002 Aug 06
  • GlyGen
  • GlycoEpitope
11821425 Molecular cloning and characterization of a novel UDP-GlcNAc:GalNAc-peptide beta1,3-N-acetylglucosaminyltransferase (beta 3Gn-T6), an enzyme synthesizing the core 3 structure of O-glycans Iwai T 2002 Apr 12
  • PubChem
PubAnnotation
Displaying entries 1 - 5 of 9 in total
Title Authors Source Publication Date PubMed ID
The Quest for Anticancer Vaccines: Deciphering the Fine-Epitope Specificity of Cancer-Related Monoclonal Antibodies by Combining Microarray Screening and Saturation Transfer Difference NMR.
  • Coelho H
  • Matsushita T
  • Artigas G
  • Hinou H
  • Cañada FJ
  • Lo-Man R
  • Leclerc C
  • Cabrita EJ
  • Jiménez-Barbero J
  • Nishimura S
  • Garcia-Martín F
  • Marcelo F
J Am Chem Soc 2015 Oct 7 26366611
Single molecule study of heterotypic interactions between mucins possessing the Tn cancer antigen.
  • Haugstad KE
  • Stokke BT
  • Brewer CF
  • Gerken TA
  • Sletmoen M
Glycobiology 2015 May 25527429
Loss of Core 1-derived O-Glycans Decreases Breast Cancer Development in Mice.
  • Song K
  • Herzog BH
  • Fu J
  • Sheng M
  • Bergstrom K
  • McDaniel JM
  • Kondo Y
  • McGee S
  • Cai X
  • Li P
  • Chen H
  • Xia L
J Biol Chem 2015 Aug 14 26124270
Identification of distinct glycoforms of IgA1 in plasma from patients with immunoglobulin A (IgA) nephropathy and healthy individuals.
  • Lehoux S
  • Mi R
  • Aryal RP
  • Wang Y
  • Schjoldager KT
  • Clausen H
  • van Die I
  • Han Y
  • Chapman AB
  • Cummings RD
  • Ju T
Mol Cell Proteomics 2014 Nov 25071157
Human T cell activation results in extracellular signal-regulated kinase (ERK)-calcineurin-dependent exposure of Tn antigen on the cell surface and binding of the macrophage galactose-type lectin (MGL).
  • van Vliet SJ
  • Vuist IM
  • Lenos K
  • Tefsen B
  • Kalay H
  • García-Vallejo JJ
  • van Kooyk Y
J Biol Chem 2013 Sep 20 23918927

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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01


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