G98544DH

Summary
GlyTouCan ID
G98544DH
IUPAC Condensed
Neu5Ac(a2-8)Neu5Ac(a2-3)Gal(b1-4)Glc(b1-
Motifs
9-O-Acetyl GD3 GD3
Subsumption Level
Fully-defined saccharide
Monoisotopic Mass
924.31
GlyGen
ChEBI
PubChem Compound
PubChem Substance
GlycoShape
Displaying 1 entry
Archetype α β
G10158SF
G58409WK
G98544DH
3D Structures
Organisms
Taxonomic Hierarchy
GlycoGene Database (GGDB)
Displaying all 4 entries
Gene Symbol Donor Acceptor Reducing terminal(Acceptor) Product Reducing terminal(Product) Reference
ST8SIA6 CMP-Neu5Ac
G91237TK
Cer
G98544DH
Cer
ST8SIA1 CMP-Neu5Ac
G91237TK
Cer
G98544DH
Cer
ST8SIA5 CMP-Neu5Ac
G98544DH
Cer
G93899SO
Cer
ST8SIA3 CMP-Neu5Ac
G91237TK
Cer
G98544DH
Cer
Displaying entries 1 - 5 of 7 in total
Gene Symbol Donor Acceptor Reducing terminal(Acceptor) Product Reducing terminal(Product) Reference
ST8SIA6 CMP-Neu5Ac
G91237TK
G98544DH
ST8SIA6 CMP-Neu5Ac
G91237TK
Cer
G98544DH
Cer
ST8SIA1 CMP-Neu5Ac
G91237TK
Cer
G98544DH
Cer
ST8SIA5 CMP-Neu5Ac
G98544DH
Cer
G93899SO
Cer
ST8SIA3 CMP-Neu5Ac
G91237TK
Cer
G98544DH
Cer
Displaying all 5 entries
Gene Symbol Donor Acceptor Reducing terminal(Acceptor) Reference
ST8SIA1 CMP-Neu5Ac
G98544DH
Cer
ST8SIA2 CMP-Neu5Ac
G98544DH
Cer
ST8SIA6 CMP-Neu5Ac
G98544DH
Cer
B4GALNT2 UDP-GalNAc
G98544DH
Cer
B3GALNT1 UDP-GalNAc
G98544DH
Cer
KEGG BRITE Database
KEGG ID
Enzyme
Reactions
GlycoEpitope
Epitope ID
EP0062
Epitope Name
N-Acetyl GD3
Sequence Descriptors
GlycoCT
RES
1b:b-dglc-HEX-1:5
2b:b-dgal-HEX-1:5
3b:a-dgro-dgal-NON-2:6|1:a|2:keto|3:d
4s:n-acetyl
5b:a-dgro-dgal-NON-2:6|1:a|2:keto|3:d
6s:n-acetyl
LIN
1:1o(4+1)2d
2:2o(3+2)3d
3:3d(5+1)4n
4:3o(8+2)5d
5:5d(5+1)6n
WURCS
WURCS=2.0/3,4,3/[a2122h-1b_1-5][a2112h-1b_1-5][Aad21122h-2a_2-6_5*NCC/3=O]/1-2-3-3/a4-b1_b3-c2_c8-d2
Literature
Displaying entries 41 - 48 of 48 in total
PubMed ID Title First Author Publication Date Source
3791209 Fluctuations in the expression of a glycolipid antigen associated with differentiation of melanoma cells monitored by a monoclonal antibody, Leo Mel 3 Werkmeister JA 1987 Jan 01
  • GlyGen
  • GlycoEpitope
2435716 Monoclonal antibody Leo Mel 3, which inhibits killing of human melanoma cells by anomalous killer cells, binds to a sugar sequence in GD2 (II3(NeuAc)2-GgOse3Cer) and several other gangliosides Fukuta S 1987 Apr 05
  • GlyGen
  • GlycoEpitope
3031684 Cell-surface antigens of melanoma recognized by human monoclonal antibodies Yamaguchi H 1987 Apr
  • GlyGen
  • GlycoEpitope
3019521 Biosynthesis and expression of the disialoganglioside GD2, a relevant target antigen on small cell lung carcinoma for monoclonal antibody-mediated cytolysis Cheresh DA 1986 Oct
  • GlyGen
  • GlycoEpitope
3005335 Disialogangliosides GD2 and GD3 are involved in the attachment of human melanoma and neuroblastoma cells to extracellular matrix proteins Cheresh DA 1986 Mar
  • GlyGen
  • GlycoEpitope
3840699 Mouse monoclonal antibodies with specificity for the melanoma-associated ganglioside disialyllactosylceramide (GD3) also react with the structural analogue disialylparagloboside Brodin T 1985 Dec 04
  • GlyGen
  • GlycoEpitope
6385004 Localization of the gangliosides GD2 and GD3 in adhesion plaques and on the surface of human melanoma cells Cheresh DA 1984 Sep
  • GlyGen
  • GlycoEpitope
7061953 GD3, a prominent ganglioside of human melanoma. Detection and characterisation by mouse monoclonal antibody Pukel CS 1982 Apr 01
  • GlyGen
  • GlycoEpitope
PubAnnotation
Displaying entries 6 - 10 of 10 in total
Title Authors Source Publication Date PubMed ID
Trafficking of ganglioside GD3 to mitochondria by tumor necrosis factor-alpha.
  • García-Ruiz C
  • Colell A
  • Morales A
  • Calvo M
  • Enrich C
  • Fernández-Checa JC
J Biol Chem 2002 Sep 27 12118012
Inhibition of integrin-linked kinase/protein kinase B/Akt signaling: mechanism for ganglioside-induced apoptosis.
  • Wang XQ
  • Sun P
  • Paller AS
J Biol Chem 2001 Nov 30 11577096
A synthetic approach to polysialogangliosides containing alpha-sialyl-(2-->8)-sialic acid: total synthesis of ganglioside GD3.
  • Ishida H
  • Ohta Y
  • Tsukada Y
  • Kiso M
  • Hasegawa A
Carbohydr Res 1993 Aug 17 8370046
Specific staining on thin-layer chromatograms of glycosphingolipids of neolacto series and gangliosides with a terminal N-acetylneuraminyl residue by different procedures with wheat germ agglutinin.
  • Higashi H
  • Sugii T
  • Kato S
Biochim Biophys Acta 1988 Nov 25 2461740
Proton NMR and fast-atom bombardment mass spectrometry analysis of the melanoma-associated ganglioside 9-O-acetyl-GD3.
  • Thurin J
  • Herlyn M
  • Hindsgaul O
  • Strömberg N
  • Karlsson KA
  • Elder D
  • Steplewski Z
  • Koprowski H
J Biol Chem 1985 Nov 25 4055789

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