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MIRAGE
Plasminogen

Summary
UniProt ID
P00747
Gene Symbol
  • PLG
Gene ID
5340
Organism
Homo sapiens (human)
GlycoProtDB
GPDB0011281
GlyConnect
GlyGen
P00747
PubChem
P00747
The Human Metabolome Database
HMDBP01984
RaftProt
P00747
Re-Glyco
P00747
Annotation
Keyword
  • 3D-structure
  • Cleavage on pair of basic residues
  • Direct protein sequencing
  • Disease variant
  • Disulfide bond
  • Fibrinolysis
  • Glycoprotein
  • Kringle
  • Phosphoprotein
  • Reference proteome
  • Repeat
  • Secreted
  • Serine protease
  • Signal
  • Thrombophilia
  • Tissue remodeling
  • Zymogen
Gene Ontology (GO)
Displaying all 9 entries
GO Term
extracellular region
extracellular space
plasma membrane
collagen-containing extracellular matrix
external side of plasma membrane
cell surface
extracellular exosome
blood microparticle
platelet alpha granule lumen
Subcellular Location(GO Annotation)

Subcellular in which this glycoprotein is expressed are highlighted in blue.

Annotation information from UniProt.
Sequence
MEHKEVVLLLLLFLKSGQGEPLDDYVNTQGASLFSVTKKQLGAGSIEECAAKCEEDEEFTCRAFQYHSKEQQCVIMAENRKSSIIIRMRDVVLFEKKVYLSECKTGNGKNYRGTMSKTKNGITCQKWSSTSPHRPRFSPATHPSEGLEENYCRNPDNDPQGPWCYTTDPEKRYDYCDILECEEECMHCSGENYDGKISKTMSGLECQAWDSQSPHAHGYIPSKFPNKNLKKNYCRNPDRELRPWCFTTDPNKRWELCDIPRCTTPPPSSGPTYQCLKGTGENYRGNVAVTVSGHTCQHWSAQTPHTHNRTPENFPCKNLDENYCRNPDGKRAPWCHTTNSQVRWEYCKIPSCDSSPVSTEQLAPTAPPELTPVVQDCYHGDGQSYRGTSSTTTTGKKCQSWSSMTPHRHQKTPENYPNAGLTMNYCRNPDADKGPWCFTTDPSVRWEYCNLKKCSGTEASVVAPPPVVLLPDVETPSEEDCMFGNGKGYRGKRATTVTGTPCQDWAAQEPHRHSIFTPETNPRAGLEKNYCRNPDGDVGGPWCYTTNPRKLYDYCDVPQCAAPSFDCGKPQVEPKKCPGRVVGGCVAHPHSWPWQVSLRTRFGMHFCGGTLISPEWVLTAAHCLEKSPRPSSYKVILGAHQEVNLEPHVQEIEVSRLFLEPTRKDIALLKLSSPAVITDKVIPACLPSPNYVVADRTECFITGWGETQGTFGAGLLKEAQLPVIENKVCNRYEFLNGRVQSTELCAGHLAGGTDSCQGDSGGPLVCFEKDKYILQGVTSWGLGCARPNKPGVYVRVSRFVTWIEGVMRNN
  • N : N-glycosylation Site
  • ___ : Potential Sequon
Glycosylation Sites
Displaying entries 1 - 10 of 19 in total
Position Description PubMed ID GlyTouCan ID Source
28
150
262
263
264
268 O-linked (GalNAc...) serine
290
308 N-linked (GlcNAc...) asparagine
349
358
Feature
  • ProtVista GlyGen : Glycosylation Site from GlyGen
  • ProtVista UniProt : Glycosylation Site from UniProt
Pathway
Displaying all 6 entries
Pathway Name Organism
Activation of Matrix Metalloproteinases Homo sapiens
Degradation of the extracellular matrix Homo sapiens
Dissolution of Fibrin Clot Homo sapiens
Platelet degranulation Homo sapiens
Regulation of IGF Activity by IGFBP Homo sapiens
Signaling by PDGF Homo sapiens
Disease
Displaying all 5 entries
DO ID Disease Name Source
DOID:0080600 COVID-19
DOID:0111592 plasminogen deficiency type I
DOID:14735 hereditary angioedema
DOID:2452 thrombophilia
DOID:6195 conjunctivitis
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International Collaboration

GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: April 7, 2025