GlyCosmos Portal

Apolipoprotein C-II

UniProt ID

P02655

Gene Symbol

Gene ID

344

Organism

Homo sapiens (human)

Keyword

Displaying **all 8** entries
GO Term
extracellular region
extracellular space
chylomicron
early endosome
very-low-density lipoprotein particle
low-density lipoprotein particle
intermediate-density lipoprotein particle
spherical high-density lipoprotein particle

Subcellular Location(GO Annotation)

Subcellular in which this glycoprotein is expressed are highlighted in blue.

Displaying entries **1 - 10** of 21 in total

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GO Term
positive regulation of phospholipase activity
positive regulation of triglyceride catabolic process
positive regulation of very-low-density lipoprotein particle remodeling
negative regulation of cholesterol transport
triglyceride-rich lipoprotein particle remodeling
chylomicron remodeling
positive regulation of fatty acid biosynthetic process
positive regulation of lipoprotein lipase activity
positive regulation of phospholipid catabolic process
negative regulation of very-low-density lipoprotein particle clearance

Displaying **all 6** entries
GO Term
phospholipase activator activity
lipoprotein lipase activator activity
molecular function activator activity
lipid binding
phospholipase binding
lipase inhibitor activity

Annotation information from UniProt.

Sequence

MGTRLLPALFLVLLVLGFEVQGTQQPQQDEMPSPTFLTQVKESLSSYWESAKTAAQNLYEKTYLPAVDEKLRDLYSKSTAAMSTYTGIFTDQVLSVLKGEE

Glycosylation Sites

Displaying **all 4** entries
Position	GlyTouCan ID	Source
23	G43417UB G29068FM	GlyGen
33	G43417UB	GlyGen
35	G43417UB G29068FM	GlyGen
42	G57321FI	GlyGen

Feature

Pathway

Displaying **all 6** entries
Pathway Name	Organism
Assembly of active LPL and LIPC lipase complexes	Homo sapiens
Chylomicron assembly	Homo sapiens
Chylomicron remodeling	Homo sapiens
HDL remodeling	Homo sapiens
LXRs regulate gene expression linked to cholesterol transport and efflux	Homo sapiens
Retinoid metabolism and transport	Homo sapiens

Disease

Displaying **all 3** entries
DO ID	Disease Name	Source
DOID:0111418	familial apolipoprotein C-II deficiency	Alliance of Genome Resources
DOID:1168	familial hyperlipidemia	Alliance of Genome Resources
DOID:2377	multiple sclerosis	Alliance of Genome Resources