GlyCosmos Portal

Submissions

Secretory phospholipase A2 receptor

Summary

GlyCosmos Lectin

GL_001087

Lectin Name Aliases

180 kDa secretory phospholipase A2 receptor
C-type lectin domain family 13 member C
M-type receptor
PLA2-R
PLA2R

Organism

Homo sapiens (human)

External Links

UniProt: Q13018

Annotation

Keyword: 3D-structure Alternative splicing Cell membrane Disulfide bond Endocytosis Glycoprotein Lectin Proteomics identification Receptor Reference proteome Repeat Secreted Signal Transmembrane helix

Gene Ontology (GO)

Displaying entries **1 - 5** of 15 in total

1

2

3

Next ›

Last »
GO Term	Evidence Code	Reference
positive regulation of cytokine production	IMP	PMID
receptor-mediated endocytosis	IDA	PMID
receptor-mediated endocytosis	IBA	GO_REF
receptor-mediated endocytosis	IEA	GO_REF GO_REF
positive regulation of DNA damage response, signal transduction by p53 class mediator	IMP	PMID

GO Hierarchy

biological process

cellular process [inference]

metabolic process [inference]

reactive oxygen species metabolic process

vesicle-mediated transport [inference]

endocytosis [inference]

receptor-mediated endocytosis

cell cycle process [inference]

replicative senescence

cellular senescence [inference]

stress-induced premature senescence [inference]

oxidative stress-induced premature senescence

localization [inference]

establishment of localization [inference]

transport [inference]

vesicle-mediated transport [inference]

endocytosis [inference]

receptor-mediated endocytosis

import into cell [inference]

endocytosis [inference]

receptor-mediated endocytosis

biological regulation [inference]

regulation of biological process [inference]

regulation of signaling [inference]

regulation of signal transduction [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of signal transduction by p53 class mediator [inference]

positive regulation of DNA damage response, signal transduction by p53 class mediator

regulation of intracellular signal transduction [inference]

regulation of signal transduction by p53 class mediator [inference]

regulation of DNA damage response, signal transduction by p53 class mediator [inference]

positive regulation of DNA damage response, signal transduction by p53 class mediator

positive regulation of signal transduction by p53 class mediator [inference]

positive regulation of DNA damage response, signal transduction by p53 class mediator

positive regulation of intracellular signal transduction [inference]

positive regulation of signal transduction by p53 class mediator [inference]

positive regulation of DNA damage response, signal transduction by p53 class mediator

positive regulation of signaling [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of signal transduction by p53 class mediator [inference]

positive regulation of DNA damage response, signal transduction by p53 class mediator

regulation of localization [inference]

regulation of transport [inference]

regulation of lipid transport [inference]

negative regulation of lipid transport [inference]

negative regulation of fatty acid transport [inference]

negative regulation of icosanoid secretion [inference]

negative regulation of arachidonic acid secretion

positive regulation of lipid transport [inference]

positive regulation of fatty acid transport [inference]

positive regulation of icosanoid secretion [inference]

positive regulation of arachidonic acid secretion

regulation of fatty acid transport [inference]

regulation of icosanoid secretion [inference]

negative regulation of icosanoid secretion [inference]

negative regulation of arachidonic acid secretion

positive regulation of icosanoid secretion [inference]

positive regulation of arachidonic acid secretion

regulation of arachidonate secretion [inference]

negative regulation of fatty acid transport [inference]

negative regulation of icosanoid secretion [inference]

negative regulation of arachidonic acid secretion

positive regulation of fatty acid transport [inference]

positive regulation of icosanoid secretion [inference]

positive regulation of arachidonic acid secretion

regulation of organic acid transport [inference]

negative regulation of organic acid transport [inference]

negative regulation of fatty acid transport [inference]

negative regulation of icosanoid secretion [inference]

negative regulation of arachidonic acid secretion

positive regulation of organic acid transport [inference]

positive regulation of fatty acid transport [inference]

positive regulation of icosanoid secretion [inference]

positive regulation of arachidonic acid secretion

regulation of fatty acid transport [inference]

regulation of icosanoid secretion [inference]

negative regulation of icosanoid secretion [inference]

negative regulation of arachidonic acid secretion

positive regulation of icosanoid secretion [inference]

positive regulation of arachidonic acid secretion

regulation of arachidonate secretion [inference]

negative regulation of fatty acid transport [inference]

negative regulation of icosanoid secretion [inference]

negative regulation of arachidonic acid secretion

positive regulation of fatty acid transport [inference]

positive regulation of icosanoid secretion [inference]

positive regulation of arachidonic acid secretion

regulation of secretion [inference]

regulation of icosanoid secretion [inference]

negative regulation of icosanoid secretion [inference]

negative regulation of arachidonic acid secretion

positive regulation of icosanoid secretion [inference]

positive regulation of arachidonic acid secretion

regulation of arachidonate secretion [inference]

positive regulation of secretion [inference]

positive regulation of icosanoid secretion [inference]

positive regulation of arachidonic acid secretion

negative regulation of secretion [inference]

negative regulation of icosanoid secretion [inference]

negative regulation of arachidonic acid secretion

positive regulation of transport [inference]

positive regulation of lipid transport [inference]

positive regulation of fatty acid transport [inference]

positive regulation of icosanoid secretion [inference]

positive regulation of arachidonic acid secretion

positive regulation of organic acid transport [inference]

positive regulation of fatty acid transport [inference]

positive regulation of icosanoid secretion [inference]

positive regulation of arachidonic acid secretion

positive regulation of secretion [inference]

positive regulation of icosanoid secretion [inference]

positive regulation of arachidonic acid secretion

negative regulation of transport [inference]

negative regulation of lipid transport [inference]

negative regulation of fatty acid transport [inference]

negative regulation of icosanoid secretion [inference]

negative regulation of arachidonic acid secretion

negative regulation of organic acid transport [inference]

negative regulation of fatty acid transport [inference]

negative regulation of icosanoid secretion [inference]

negative regulation of arachidonic acid secretion

negative regulation of secretion [inference]

negative regulation of icosanoid secretion [inference]

negative regulation of arachidonic acid secretion

regulation of lipid localization [inference]

regulation of lipid transport [inference]

negative regulation of lipid transport [inference]

negative regulation of fatty acid transport [inference]

negative regulation of icosanoid secretion [inference]

negative regulation of arachidonic acid secretion

positive regulation of lipid transport [inference]

positive regulation of fatty acid transport [inference]

positive regulation of icosanoid secretion [inference]

positive regulation of arachidonic acid secretion

regulation of fatty acid transport [inference]

regulation of icosanoid secretion [inference]

negative regulation of icosanoid secretion [inference]

negative regulation of arachidonic acid secretion

positive regulation of icosanoid secretion [inference]

positive regulation of arachidonic acid secretion

regulation of arachidonate secretion [inference]

negative regulation of fatty acid transport [inference]

negative regulation of icosanoid secretion [inference]

negative regulation of arachidonic acid secretion

positive regulation of fatty acid transport [inference]

positive regulation of icosanoid secretion [inference]

positive regulation of arachidonic acid secretion

negative regulation of lipid localization [inference]

negative regulation of lipid transport [inference]

negative regulation of fatty acid transport [inference]

negative regulation of icosanoid secretion [inference]

negative regulation of arachidonic acid secretion

positive regulation of lipid localization [inference]

positive regulation of lipid transport [inference]

positive regulation of fatty acid transport [inference]

positive regulation of icosanoid secretion [inference]

positive regulation of arachidonic acid secretion

positive regulation of biological process [inference]

positive regulation of signaling [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of signal transduction by p53 class mediator [inference]

positive regulation of DNA damage response, signal transduction by p53 class mediator

positive regulation of cellular process [inference]

positive regulation of metabolic process [inference]

positive regulation of biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production

positive regulation of macromolecule metabolic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production

positive regulation of cell communication [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of signal transduction by p53 class mediator [inference]

positive regulation of DNA damage response, signal transduction by p53 class mediator

positive regulation of programmed cell death [inference]

positive regulation of apoptotic process [inference]

positive regulation of epithelial cell apoptotic process [inference]

positive regulation of podocyte apoptotic process

positive regulation of response to stimulus [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of signal transduction by p53 class mediator [inference]

positive regulation of DNA damage response, signal transduction by p53 class mediator

positive regulation of transport [inference]

positive regulation of lipid transport [inference]

positive regulation of fatty acid transport [inference]

positive regulation of icosanoid secretion [inference]

positive regulation of arachidonic acid secretion

positive regulation of organic acid transport [inference]

positive regulation of fatty acid transport [inference]

positive regulation of icosanoid secretion [inference]

positive regulation of arachidonic acid secretion

positive regulation of secretion [inference]

positive regulation of icosanoid secretion [inference]

positive regulation of arachidonic acid secretion

positive regulation of multicellular organismal process [inference]

positive regulation of cytokine production

positive regulation of lipid localization [inference]

positive regulation of lipid transport [inference]

positive regulation of fatty acid transport [inference]

positive regulation of icosanoid secretion [inference]

positive regulation of arachidonic acid secretion

negative regulation of biological process [inference]

negative regulation of transport [inference]

negative regulation of lipid transport [inference]

negative regulation of fatty acid transport [inference]

negative regulation of icosanoid secretion [inference]

negative regulation of arachidonic acid secretion

negative regulation of organic acid transport [inference]

negative regulation of fatty acid transport [inference]

negative regulation of icosanoid secretion [inference]

negative regulation of arachidonic acid secretion

negative regulation of secretion [inference]

negative regulation of icosanoid secretion [inference]

negative regulation of arachidonic acid secretion

negative regulation of lipid localization [inference]

negative regulation of lipid transport [inference]

negative regulation of fatty acid transport [inference]

negative regulation of icosanoid secretion [inference]

negative regulation of arachidonic acid secretion

regulation of response to stimulus [inference]

regulation of signal transduction [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of signal transduction by p53 class mediator [inference]

positive regulation of DNA damage response, signal transduction by p53 class mediator

regulation of intracellular signal transduction [inference]

regulation of signal transduction by p53 class mediator [inference]

regulation of DNA damage response, signal transduction by p53 class mediator [inference]

positive regulation of DNA damage response, signal transduction by p53 class mediator

positive regulation of signal transduction by p53 class mediator [inference]

positive regulation of DNA damage response, signal transduction by p53 class mediator

positive regulation of intracellular signal transduction [inference]

positive regulation of signal transduction by p53 class mediator [inference]

positive regulation of DNA damage response, signal transduction by p53 class mediator

positive regulation of response to stimulus [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of signal transduction by p53 class mediator [inference]

positive regulation of DNA damage response, signal transduction by p53 class mediator

regulation of response to stress [inference]

regulation of cellular response to stress [inference]

regulation of DNA damage response, signal transduction by p53 class mediator [inference]

positive regulation of DNA damage response, signal transduction by p53 class mediator

regulation of cellular process [inference]

regulation of cell communication [inference]

regulation of signal transduction [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of signal transduction by p53 class mediator [inference]

positive regulation of DNA damage response, signal transduction by p53 class mediator

regulation of intracellular signal transduction [inference]

regulation of signal transduction by p53 class mediator [inference]

regulation of DNA damage response, signal transduction by p53 class mediator [inference]

positive regulation of DNA damage response, signal transduction by p53 class mediator

positive regulation of signal transduction by p53 class mediator [inference]

positive regulation of DNA damage response, signal transduction by p53 class mediator

positive regulation of intracellular signal transduction [inference]

positive regulation of signal transduction by p53 class mediator [inference]

positive regulation of DNA damage response, signal transduction by p53 class mediator

positive regulation of cell communication [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of signal transduction by p53 class mediator [inference]

positive regulation of DNA damage response, signal transduction by p53 class mediator

regulation of metabolic process [inference]

regulation of biosynthetic process [inference]

positive regulation of biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of cytokine production [inference]

positive regulation of cytokine production

positive regulation of gene expression [inference]

positive regulation of cytokine production

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production

positive regulation of metabolic process [inference]

positive regulation of biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production

positive regulation of macromolecule metabolic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production

regulation of macromolecule metabolic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of cytokine production [inference]

positive regulation of cytokine production

positive regulation of gene expression [inference]

positive regulation of cytokine production

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production

positive regulation of macromolecule metabolic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production

regulation of programmed cell death [inference]

regulation of apoptotic process [inference]

positive regulation of apoptotic process [inference]

positive regulation of epithelial cell apoptotic process [inference]

positive regulation of podocyte apoptotic process

regulation of epithelial cell apoptotic process [inference]

positive regulation of epithelial cell apoptotic process [inference]

positive regulation of podocyte apoptotic process

regulation of podocyte apoptotic process [inference]

positive regulation of podocyte apoptotic process

positive regulation of programmed cell death [inference]

positive regulation of apoptotic process [inference]

positive regulation of epithelial cell apoptotic process [inference]

positive regulation of podocyte apoptotic process

positive regulation of cellular process [inference]

positive regulation of metabolic process [inference]

positive regulation of biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production

positive regulation of macromolecule metabolic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production

positive regulation of cell communication [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of signal transduction by p53 class mediator [inference]

positive regulation of DNA damage response, signal transduction by p53 class mediator

positive regulation of programmed cell death [inference]

positive regulation of apoptotic process [inference]

positive regulation of epithelial cell apoptotic process [inference]

positive regulation of podocyte apoptotic process

regulation of cellular response to stress [inference]

regulation of DNA damage response, signal transduction by p53 class mediator [inference]

positive regulation of DNA damage response, signal transduction by p53 class mediator

regulation of multicellular organismal process [inference]

regulation of cytokine production [inference]

positive regulation of cytokine production

positive regulation of multicellular organismal process [inference]

positive regulation of cytokine production

Displaying entries **6 - 10** of 10 in total

« First

‹ Prev

1

2
GO Term	Evidence Code	Reference
plasma membrane	IBA	GO_REF
plasma membrane	IEA	GO_REF
cell surface	IDA	PMID
signaling receptor complex	IDA	PMID
signaling receptor complex	IBA	GO_REF

GO Hierarchy

cellular component

protein-containing complex [inference]

signaling receptor complex

cellular anatomical structure [inference]

membrane [inference]

plasma membrane

Displaying **all 5** entries
GO Term	Evidence Code	Reference
phospholipase A2 inhibitor activity	ISS	GO_REF
carbohydrate binding
signaling receptor activity	IDA	PMID
phospholipase binding	IPI	PMID
phospholipase binding	IEA	GO_REF GO_REF

GO Hierarchy

molecular function

binding [inference]

protein binding [inference]

enzyme binding [inference]

phospholipase binding

carbohydrate binding

molecular transducer activity [inference]

signaling receptor activity

molecular function regulator activity [inference]

enzyme regulator activity [inference]

enzyme inhibitor activity [inference]

lipase inhibitor activity [inference]

phospholipase inhibitor activity [inference]

phospholipase A2 inhibitor activity

molecular function inhibitor activity [inference]

enzyme inhibitor activity [inference]

lipase inhibitor activity [inference]

phospholipase inhibitor activity [inference]

phospholipase A2 inhibitor activity

Gene Ontology information from UniProt.

Annotation information from UniProt.

Pathway

Displaying **all 6** entries
Pathway Name	Organism
Acyl chain remodelling of PC	Homo sapiens
Acyl chain remodelling of PE	Homo sapiens
Acyl chain remodelling of PG	Homo sapiens
Acyl chain remodelling of PI	Homo sapiens
Acyl chain remodelling of PS	Homo sapiens
Synthesis of PA	Homo sapiens

PDB

6JLI

7QSR

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

All Resources

Other Information

Tools

Search Tools

Guidelines

Summary

External Links

Annotation

PDB

International Collaboration

Acknowledgements