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Scavenging by Class A Receptors

Summary

Organism

Homo sapiens (human)

Reactome

R-HSA-3000480

PubChem

R-HSA-3000480

Description

Class A scavenger receptors contain an intracellular domain, a transmembrane region, a coiled-coil domain, a collagenous domain, and the SR cysteine-rich domain (reviewed in Areschoug and Gordon 2009, Bowdish and Gordon 2009). The coiled coil domains interact to form trimers. The collagenous domain (Rohrer et al. 1990, Acton et al. 1993) and/or the SR cysteine-rich domain (Brannstrom et al. 2002) bind ligands and determine the specificity of the receptor.

Click on a node on the pathway to see its details. Glycoproteins are marked with a glycoprotein icon in their name.

SPV: a JavaScript Signaling Pathway Visualizer, Bioinformatics, 2018

Displaying entries **1 - 10** of 16 in total

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UniProt ID	Protein Name	Gene Symbol	Pathway Viewer
P02452	Collagen alpha-1(I) chain	COL1A1	view
P02461	Collagen alpha-1(III) chain	COL3A1	view
P02462	Collagen alpha-1(IV) chain	COL4A1	view
P02647	Apolipoprotein A-I	APOA1	view
P02649	Apolipoprotein E	APOE	view
P02794	Ferritin heavy chain	FTH FTH1 FTHL6 OK/SW-cl.84 PIG15	view
P04114	Apolipoprotein B-100	APOB	view
P08123	Collagen alpha-2(I) chain	COL1A2	view
P08572	Collagen alpha-2(IV) chain	COL4A2	view
P14625	Endoplasmin	GRP94 HEL-S-125m HEL35 HSP90B1 HSPC4 TRA1 hCG_21864	view

Displaying **all 3** entries
GlyCosmos Lectin	UniProt ID	Lectin Name	Pathway Viewer
GL_000272	P27797	Calreticulin	view
GL_001998	Q5KU26	Collectin-12	view
GL_002404	Q9BWP8	Collectin-11	view

Displaying **all 3** entries
GlyTouCan ID	ChEBI	Pathway Viewer
G27025MB	28037	view
G70323CJ	4208	view
G82576YO	2181	view

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