GlyCosmos Portal

Submissions

G00031MO

Summary

GlyTouCan ID: G00031MO
IUPAC Condensed: Gal(b1-3)GalNAc(a1-
Motifs: O-Glycan core 1 T antigen TF antigen
Subsumption Level: Fully-defined saccharide
Monoisotopic Mass: 383.14

External Links

GlyConnect structure

1947

GlyGen

G00031MO

ChEBI

61820

PubChem Compound

5288347

PubChem Substance

252294787

CarbBank

3D Structures

GLYCAM: DGalpb1-3DGalpNAca1-OH

GlycoShape

G00031MO

Displaying 1 entry
Archetype	α	β
G00032MO	G00031MO	G01534TU

Organisms

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Organisms	Evidence
Gadus	GlyTouCan(glycome-db)
Cricetulus griseus (Chinese hamster)	GlyTouCan(glycome-db)
Mus musculus (house mouse)	GlyConnectStructure GlyTouCan(glycome-db) GlycoEpitope
Bos taurus (domestic cattle)	GlyTouCan(glycome-db)
Rattus	GlyTouCan(glycome-db)

Taxonomic Hierarchy

root

Viruses [inference]

Riboviria [inference]

Orthornavirae [inference]

Pisuviricota [inference]

Pisoniviricetes [inference]

Nidovirales [inference]

Cornidovirineae [inference]

Coronaviridae [inference]

Orthocoronavirinae [inference]

Betacoronavirus [inference]

Sarbecovirus [inference]

Severe acute respiratory syndrome-related coronavirus [inference]

Severe acute respiratory syndrome coronavirus 2

cellular organisms [inference]

Eukaryota (eucaryotes) [inference]

Opisthokonta [inference]

Metazoa (metazoans) [inference]

Eumetazoa [inference]

Bilateria [inference]

Deuterostomia [inference]

Chordata (chordates) [inference]

Craniata [inference]

Vertebrata (vertebrates) [inference]

Gnathostomata (jawed vertebrates) [inference]

Teleostomi [inference]

Euteleostomi (bony vertebrates) [inference]

Actinopterygii (ray-finned fishes) [inference]

Actinopteri [inference]

Neopterygii [inference]

Teleostei (teleost fishes) [inference]

Osteoglossocephalai [inference]

Clupeocephala [inference]

Euteleosteomorpha [inference]

Neoteleostei [inference]

Eurypterygia [inference]

Ctenosquamata [inference]

Acanthomorphata [inference]

Paracanthopterygii [inference]

Zeiogadaria [inference]

Gadariae [inference]

Gadiformes (cods and others) [inference]

Gadoidei [inference]

Gadidae (cods) [inference]

Gadus

Gadus chalcogrammus (walleye pollock)

Pollachius [inference]

Pollachius pollachius (pollack)

Sarcopterygii [inference]

Dipnotetrapodomorpha [inference]

Tetrapoda (tetrapods) [inference]

Amniota (amniotes) [inference]

Mammalia (mammals) [inference]

Theria [inference]

Eutheria (placentals) [inference]

Boreoeutheria [inference]

Euarchontoglires [inference]

Primates [inference]

Haplorrhini [inference]

Simiiformes [inference]

Catarrhini [inference]

Cercopithecoidea [inference]

Cercopithecidae (Old World monkeys) [inference]

Cercopithecinae [inference]

Macaca (macaques) [inference]

Macaca mulatta (Rhesus monkey)

Hominoidea (apes) [inference]

Hominidae (great apes) [inference]

Homininae [inference]

Homo [inference]

Homo sapiens (human)

Glires (Rodents and rabbits) [inference]

Rodentia (rodent) [inference]

Myomorpha (mice and others) [inference]

Muroidea [inference]

Muridae [inference]

Murinae [inference]

Mus (mice) [inference]

Mus [inference]

Mus musculus (house mouse)

Rattus

Rattus norvegicus (Norway rat)

Cricetidae [inference]

Cricetinae (hamsters) [inference]

Cricetulus [inference]

Cricetulus griseus (Chinese hamster)

Lagomorpha [inference]

Leporidae (rabbits and hares) [inference]

Oryctolagus [inference]

Oryctolagus cuniculus (rabbit)

Laurasiatheria [inference]

Artiodactyla (even-toed ungulates & whales) [inference]

Suina [inference]

Suidae (pigs) [inference]

Sus [inference]

Sus scrofa (pig) [inference]

Sus scrofa domesticus (domestic pig)

Ruminantia [inference]

Pecora [inference]

Bovidae [inference]

Bovinae [inference]

Bos (cattle) [inference]

Bos taurus (domestic cattle)

Carnivora (carnivores) [inference]

Caniformia [inference]

Canidae (dog, coyote, wolf, fox) [inference]

Canis [inference]

Canis lupus (gray wolf) [inference]

Canis lupus familiaris (dog)

Protostomia [inference]

Ecdysozoa [inference]

Panarthropoda [inference]

Arthropoda (arthropods) [inference]

Mandibulata [inference]

Pancrustacea [inference]

Hexapoda (hexapods) [inference]

Insecta (insects) [inference]

Dicondylia [inference]

Pterygota (winged insects) [inference]

Neoptera [inference]

Endopterygota [inference]

Diptera (flies) [inference]

Brachycera [inference]

Muscomorpha [inference]

Eremoneura [inference]

Cyclorrhapha [inference]

Schizophora [inference]

Acalyptratae [inference]

Ephydroidea [inference]

Drosophilidae (pomace flies) [inference]

Drosophilinae [inference]

Drosophilini [inference]

Drosophila (fruit flies) [inference]

Sophophora [inference]

melanogaster group [inference]

melanogaster subgroup [inference]

Drosophila melanogaster (fruit fly)

Bacteria (eubacteria) [inference]

Pseudomonadota [inference]

Gammaproteobacteria [inference]

Enterobacterales [inference]

Enterobacteriaceae [inference]

Shigella [inference]

Shigella dysenteriae

FCB group [inference]

Bacteroidota/Chlorobiota group [inference]

Bacteroidota [inference]

Bacteroidia [inference]

Bacteroidales [inference]

Bacteroidaceae [inference]

Bacteroides [inference]

Bacteroides ovatus

GlycoGene Database (GGDB)

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Gene Symbol	Donor	Acceptor	Reducing terminal(Acceptor)	Product	Reducing terminal(Product)	Reference
C1GALT1	(not applicable)	G57321FI	Ser/Thr	G00031MO	Ser/Thr	11677243
ST6GALNAC1	CMP-Neu5Ac	G00031MO	Ser/Thr	G56682BC	Ser/Thr	10536037
ST3GAL2	CMP-Neu5Ac	G00031MO	R	G65562ZE	R	9266697
ST6GALNAC2	CMP-Neu5Ac	G00031MO	Ser/Thr	G56682BC	Ser/Thr	10742600
ST3GAL4	CMP-Neu5Ac	G00031MO	free	G65562ZE	free	8288606

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Gene Symbol	Donor	Acceptor	Reducing terminal(Acceptor)	Product	Reducing terminal(Product)	Reference
C1GALT1	(not applicable)	G57321FI	Ser/Thr	G00031MO	Ser/Thr	11677243
ST3GAL3	CMP-Neu5Ac	G00031MO	free	G65562ZE	free	8288606
ST6GALNAC1	CMP-Neu5Ac	G00031MO	Ser/Thr	G56682BC	Ser/Thr	10536037
ST3GAL2	CMP-Neu5Ac	G00031MO	R	G65562ZE	R	9266697
ST6GALNAC1	CMP-Neu5Ac	G00031MO	O-glycan Synthesis	G56682BC	O-glycan Synthesis

Displaying entries **11 - 14** of 14 in total

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Gene Symbol	Donor	Acceptor	Reducing terminal(Acceptor)	Reference
B3GALNT2	UDP-GalNAc	G00031MO	(core1)-pNP	14724282
B3GNT7	UDP-GlcNAc	G00031MO	core 1-pNp	15620693
B3GNT6	UDP-GlcNAc	G00031MO	[alpha]-pNP(core 1)	11821425
B3GNT8	UDP-GlcNAc	G00031MO	core 1-pNp	15620693

KEGG BRITE Database

KEGG ID

Enzyme

References

Reactions

Displaying **all 4** entries
KEGG Reaction	Enzyme	Acceptor	Product
R05908	2.4.1.122	G57321FI	G00031MO
R12704	2.4.3.3	G00031MO	G28694FA
R05912	2.4.1.102	G00031MO	G00033MO
R05913	2.4.3.4	G00031MO	G65562ZE

Core Protein

Displaying entries **21 - 30** of 50 in total

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UniProt ID	Protein Name	Reference	Source
P08575	Receptor-type tyrosine-protein phosphatase C	8122360 9492296	GlyGen GlyConnect
P0DN86	Choriogonadotropin subunit beta 3	1374031 1820200 1967025 3335536 468798 9449027	GlyGen GlyConnect GlyConnect
P0DTC2	Spike glycoprotein	33806155 33871970	GlyGen GlyConnect GlyConnect GlyConnect GlyConnect
P10645	Chromogranin-A	9852066	GlyGen GlyConnect
P10761	Zona pellucida sperm-binding protein 3	14673092	GlyGen GlyConnect
P11279	Lysosome-associated membrane glycoprotein 1	8323299	GlyGen GlyConnect
P12259	Coagulation factor V	32310329	GlyGen GlyConnect
P13473	Lysosome-associated membrane glycoprotein 2	8323299	GlyGen GlyConnect
P14780	Matrix metalloproteinase-9	11123894	GlyGen GlyConnect
P15941	Mucin-1	11445551 8969192 9530955	GlyGen GlyConnect GlyConnect GlyConnect GlyConnect GlyConnect GlyConnect GlyConnect

GlycoEpitope

Epitope ID: EP0020

Pathway

Displaying **all 8** entries
Pathway Name	Organism
E.coli O107	Escherichia coli
E.coli O117	Escherichia coli
E.coli O185	Escherichia coli
E.coli O5ab	Escherichia coli
E.coli O5ac	Escherichia coli
E.coli O70	Escherichia coli
E.coli O71	Escherichia coli
E.coli O83	Escherichia coli

Sequence Descriptors

GlycoCT

RES
1b:a-dgal-HEX-1:5
2s:n-acetyl
3b:b-dgal-HEX-1:5
LIN
1:1d(2+1)2n
2:1o(3+1)3d

WURCS

WURCS=2.0/2,2,1/[a2112h-1a_1-5_2*NCC/3=O][a2112h-1b_1-5]/1-2/a3-b1

Literature

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PubMed ID	Title	First Author	Publication Date	Source
16965854	Biological significance of cancer-associated sialyl-Tn antigen: modulation of malignant phenotype in gastric carcinoma cells	Pinho S	2007 May 08	GlyGen GlycoEpitope
17652409	Structural basis for recognition of breast and colon cancer epitopes Tn antigen and Forssman disaccharide by Helix pomatia lectin	Lescar J	2007 Jul 25	GlyGen GlycoEpitope
17537433	Galectin-1, an endogenous lectin produced by arterial cells, binds lipoprotein(a) [Lp(a)] in situ: Relevance to atherogenesis	Chellan B	2007 Dec	GlyGen GlycoEpitope
17694322	Changes in the profile of simple mucin-type O-glycans and polypeptide GalNAc-transferases in human testis and testicular neoplasms are associated with germ cell maturation and tumour differentiation	Rajpert-De Meyts E	2007 Aug 11	GlyGen GlycoEpitope
17674202	Temporal changes in the carbohydrates expressed on BG01 human embryonic stem cells during differentiation as embryoid bodies	Wearne KA	2007 Aug 03	GlyGen GlycoEpitope
17457671	The oncofetal Thomsen-Friedenreich carbohydrate antigen in cancer progression	Yu LG	2007 Apr 25	GlyGen GlycoEpitope
17100645	A Novel Antiproliferative and Antifungal Lectin from Amaranthus viridis Linn Seeds	Kaur N	2006	GlyGen GlycoEpitope
16776550	Binding of T-antigen disaccharides to Artocarpus hirsuta lectin and jacalin are energetically different	Gaikwad SM	2006 Sep	GlyGen GlycoEpitope
17057347	Structural studies on peanut lectin complexed with disaccharides involving different linkages: further insights into the structure and interactions of the lectin	Natchiar SK	2006 Nov	GlyGen GlycoEpitope PubChem
16990264	Crystal Structure of the Galectin-9 N-terminal Carbohydrate Recognition Domain from Mus musculus Reveals the Basic Mechanism of Carbohydrate Recognition	Nagae M	2006 Nov 24	GlyGen GlycoEpitope

PubAnnotation

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Title	Authors	Source	Publication Date	PubMed ID
The binding of simian virus 40 large T antigen to the polyphosphate backbone of nucleic acids.	Montenarh M Henning R	Biochim Biophys Acta	1982 Jun 30	6896661
Purification and characterization of the cytoplasmic casein kinase I from rat liver.	Pierre M Loeb JE	Biochim Biophys Acta	1982 Jan 18	6948579
Use of monoclonal antibodies as probes of simian virus 40 T antigen ATPase activity.	Clark R Lane DP Tjian R	J Biol Chem	1981 Nov 25	6170639
Characteristics of an SV40-plasmid recombinant and its movement into and out of the genome of a murine cell.	Hanahan D Lane D Lipsich L Wigler M Botchan M	Cell	1980 Aug	6250708
A stretch of "late" SV40 viral DNA about 400 bp long which includes the origin of replication is specifically exposed in SV40 minichromosomes.	Varshavsky AJ Sundin O Bohn M	Cell	1979 Feb	222461

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

All Resources

Other Information

Tools

Search Tools

Guidelines

Summary

External Links

KEGG BRITE Database

GlycoEpitope

Sequence Descriptors

International Collaboration

Acknowledgements