GlyCosmos Portal

Submissions

G00031MO

Summary

GlyTouCan ID: G00031MO
IUPAC Condensed: Gal(b1-3)GalNAc(a1-
Motifs: O-Glycan core 1 T antigen TF antigen
Subsumption Level: Fully-defined saccharide
Monoisotopic Mass: 383.14

External Links

GlyConnect structure

1947

GlyGen

G00031MO

ChEBI

61820

PubChem Compound

5288347

PubChem Substance

252294787

CarbBank

3D Structures

GLYCAM: DGalpb1-3DGalpNAca1-OH

GlycoShape

G00031MO

Displaying 1 entry
Archetype	α	β
G00032MO	G00031MO	G01534TU

Organisms

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Organisms	Evidence
Gadus	GlyTouCan(glycome-db)
Cricetulus griseus (Chinese hamster)	GlyTouCan(glycome-db)
Mus musculus (house mouse)	GlyConnectStructure GlyTouCan(glycome-db) GlycoEpitope
Bos taurus (domestic cattle)	GlyTouCan(glycome-db)
Rattus	GlyTouCan(glycome-db)

Taxonomic Hierarchy

root

Viruses [inference]

Riboviria [inference]

Orthornavirae [inference]

Pisuviricota [inference]

Pisoniviricetes [inference]

Nidovirales [inference]

Cornidovirineae [inference]

Coronaviridae [inference]

Orthocoronavirinae [inference]

Betacoronavirus [inference]

Sarbecovirus [inference]

Severe acute respiratory syndrome-related coronavirus [inference]

Severe acute respiratory syndrome coronavirus 2

cellular organisms [inference]

Eukaryota (eucaryotes) [inference]

Opisthokonta [inference]

Metazoa (metazoans) [inference]

Eumetazoa [inference]

Bilateria [inference]

Deuterostomia [inference]

Chordata (chordates) [inference]

Craniata [inference]

Vertebrata (vertebrates) [inference]

Gnathostomata (jawed vertebrates) [inference]

Teleostomi [inference]

Euteleostomi (bony vertebrates) [inference]

Actinopterygii (ray-finned fishes) [inference]

Actinopteri [inference]

Neopterygii [inference]

Teleostei (teleost fishes) [inference]

Osteoglossocephalai [inference]

Clupeocephala [inference]

Euteleosteomorpha [inference]

Neoteleostei [inference]

Eurypterygia [inference]

Ctenosquamata [inference]

Acanthomorphata [inference]

Paracanthopterygii [inference]

Zeiogadaria [inference]

Gadariae [inference]

Gadiformes (cods and others) [inference]

Gadoidei [inference]

Gadidae (cods) [inference]

Gadus

Gadus chalcogrammus (walleye pollock)

Pollachius [inference]

Pollachius pollachius (pollack)

Sarcopterygii [inference]

Dipnotetrapodomorpha [inference]

Tetrapoda (tetrapods) [inference]

Amniota (amniotes) [inference]

Mammalia (mammals) [inference]

Theria [inference]

Eutheria (placentals) [inference]

Boreoeutheria [inference]

Euarchontoglires [inference]

Primates [inference]

Haplorrhini [inference]

Simiiformes [inference]

Catarrhini [inference]

Cercopithecoidea [inference]

Cercopithecidae (Old World monkeys) [inference]

Cercopithecinae [inference]

Macaca (macaques) [inference]

Macaca mulatta (Rhesus monkey)

Hominoidea (apes) [inference]

Hominidae (great apes) [inference]

Homininae [inference]

Homo [inference]

Homo sapiens (human)

Glires (Rodents and rabbits) [inference]

Rodentia (rodent) [inference]

Myomorpha (mice and others) [inference]

Muroidea [inference]

Muridae [inference]

Murinae [inference]

Mus (mice) [inference]

Mus [inference]

Mus musculus (house mouse)

Rattus

Rattus norvegicus (Norway rat)

Cricetidae [inference]

Cricetinae (hamsters) [inference]

Cricetulus [inference]

Cricetulus griseus (Chinese hamster)

Lagomorpha [inference]

Leporidae (rabbits and hares) [inference]

Oryctolagus [inference]

Oryctolagus cuniculus (rabbit)

Laurasiatheria [inference]

Artiodactyla (even-toed ungulates & whales) [inference]

Suina [inference]

Suidae (pigs) [inference]

Sus [inference]

Sus scrofa (pig) [inference]

Sus scrofa domesticus (domestic pig)

Ruminantia [inference]

Pecora [inference]

Bovidae [inference]

Bovinae [inference]

Bos (cattle) [inference]

Bos taurus (domestic cattle)

Carnivora (carnivores) [inference]

Caniformia [inference]

Canidae (dog, coyote, wolf, fox) [inference]

Canis [inference]

Canis lupus (gray wolf) [inference]

Canis lupus familiaris (dog)

Protostomia [inference]

Ecdysozoa [inference]

Panarthropoda [inference]

Arthropoda (arthropods) [inference]

Mandibulata [inference]

Pancrustacea [inference]

Hexapoda (hexapods) [inference]

Insecta (insects) [inference]

Dicondylia [inference]

Pterygota (winged insects) [inference]

Neoptera [inference]

Endopterygota [inference]

Diptera (flies) [inference]

Brachycera [inference]

Muscomorpha [inference]

Eremoneura [inference]

Cyclorrhapha [inference]

Schizophora [inference]

Acalyptratae [inference]

Ephydroidea [inference]

Drosophilidae (pomace flies) [inference]

Drosophilinae [inference]

Drosophilini [inference]

Drosophila (fruit flies) [inference]

Sophophora [inference]

melanogaster group [inference]

melanogaster subgroup [inference]

Drosophila melanogaster (fruit fly)

Bacteria (eubacteria) [inference]

Pseudomonadota [inference]

Gammaproteobacteria [inference]

Enterobacterales [inference]

Enterobacteriaceae [inference]

Shigella [inference]

Shigella dysenteriae

FCB group [inference]

Bacteroidota/Chlorobiota group [inference]

Bacteroidota [inference]

Bacteroidia [inference]

Bacteroidales [inference]

Bacteroidaceae [inference]

Bacteroides [inference]

Bacteroides ovatus

GlycoGene Database (GGDB)

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Gene Symbol	Donor	Acceptor	Reducing terminal(Acceptor)	Product	Reducing terminal(Product)	Reference
C1GALT1	(not applicable)	G57321FI	Ser/Thr	G00031MO	Ser/Thr	11677243
ST6GALNAC1	CMP-Neu5Ac	G00031MO	Ser/Thr	G56682BC	Ser/Thr	10536037
ST3GAL2	CMP-Neu5Ac	G00031MO	R	G65562ZE	R	9266697
ST6GALNAC2	CMP-Neu5Ac	G00031MO	Ser/Thr	G56682BC	Ser/Thr	10742600
ST3GAL4	CMP-Neu5Ac	G00031MO	free	G65562ZE	free	8288606

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Gene Symbol	Donor	Acceptor	Reducing terminal(Acceptor)	Product	Reducing terminal(Product)	Reference
C1GALT1	(not applicable)	G57321FI	Ser/Thr	G00031MO	Ser/Thr	11677243
ST3GAL3	CMP-Neu5Ac	G00031MO	free	G65562ZE	free	8288606
ST6GALNAC1	CMP-Neu5Ac	G00031MO	Ser/Thr	G56682BC	Ser/Thr	10536037
ST3GAL2	CMP-Neu5Ac	G00031MO	R	G65562ZE	R	9266697
ST6GALNAC1	CMP-Neu5Ac	G00031MO	O-glycan Synthesis	G56682BC	O-glycan Synthesis

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Gene Symbol	Donor	Acceptor	Reducing terminal(Acceptor)	Reference
ST6GAL2	CMP-Neu5Ac	G00031MO	free	12235148
ST6GALNAC4	CMP-Neu5Ac	G00031MO	benzyl	11062056
ST6GALNAC3	CMP-Neu5Ac	G00031MO	Ser/Thr	10536037
ST3GAL3	CMP-Neu5Ac	G00031MO	Antifreeze glycoprotein	8288606
ST3GAL6	CMP-Neu5Ac	G00031MO	free	10206952

KEGG BRITE Database

KEGG ID

Enzyme

References

Reactions

Displaying **all 4** entries
KEGG Reaction	Enzyme	Acceptor	Product
R05908	2.4.1.122	G57321FI	G00031MO
R12704	2.4.3.3	G00031MO	G28694FA
R05912	2.4.1.102	G00031MO	G00033MO
R05913	2.4.3.4	G00031MO	G65562ZE

Core Protein

Displaying entries **11 - 20** of 50 in total

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UniProt ID	Protein Name	Reference	Source
P01880	Immunoglobulin heavy constant delta	15557177	GlyGen GlyConnect
P02668	Kappa-casein	7408862	GlyConnect
P02724	Glycophorin-A	3514617 4091823 6190803 6619126 7430095 8384526	GlyGen GlyConnect
P02787	Serotransferrin	9751792	GlyGen GlyConnect
P03393	Glycoprotein 55	8286859	GlyConnect GlyConnect
P04275	von Willebrand factor	1872845	GlyGen GlyConnect
P05059	Chromogranin-A	9115255	GlyConnect
P07314	Glutathione hydrolase 1 proenzyme	2573604	GlyGen GlyConnect
P07498	Kappa-casein	3342257	GlyGen GlyConnect
P08519	Apolipoprotein(a)	11294842	GlyGen GlyConnect

GlycoEpitope

Epitope ID: EP0020

Pathway

Displaying **all 8** entries
Pathway Name	Organism
E.coli O107	Escherichia coli
E.coli O117	Escherichia coli
E.coli O185	Escherichia coli
E.coli O5ab	Escherichia coli
E.coli O5ac	Escherichia coli
E.coli O70	Escherichia coli
E.coli O71	Escherichia coli
E.coli O83	Escherichia coli

Sequence Descriptors

GlycoCT

RES
1b:a-dgal-HEX-1:5
2s:n-acetyl
3b:b-dgal-HEX-1:5
LIN
1:1d(2+1)2n
2:1o(3+1)3d

WURCS

WURCS=2.0/2,2,1/[a2112h-1a_1-5_2*NCC/3=O][a2112h-1b_1-5]/1-2/a3-b1

Literature

Displaying entries **41 - 50** of **216** in total

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PubMed ID	Title	First Author	Publication Date	Source
16965854	Biological significance of cancer-associated sialyl-Tn antigen: modulation of malignant phenotype in gastric carcinoma cells	Pinho S	2007 May 08	GlyGen GlycoEpitope
17652409	Structural basis for recognition of breast and colon cancer epitopes Tn antigen and Forssman disaccharide by Helix pomatia lectin	Lescar J	2007 Jul 25	GlyGen GlycoEpitope
17537433	Galectin-1, an endogenous lectin produced by arterial cells, binds lipoprotein(a) [Lp(a)] in situ: Relevance to atherogenesis	Chellan B	2007 Dec	GlyGen GlycoEpitope
17694322	Changes in the profile of simple mucin-type O-glycans and polypeptide GalNAc-transferases in human testis and testicular neoplasms are associated with germ cell maturation and tumour differentiation	Rajpert-De Meyts E	2007 Aug 11	GlyGen GlycoEpitope
17674202	Temporal changes in the carbohydrates expressed on BG01 human embryonic stem cells during differentiation as embryoid bodies	Wearne KA	2007 Aug 03	GlyGen GlycoEpitope
17457671	The oncofetal Thomsen-Friedenreich carbohydrate antigen in cancer progression	Yu LG	2007 Apr 25	GlyGen GlycoEpitope
17100645	A Novel Antiproliferative and Antifungal Lectin from Amaranthus viridis Linn Seeds	Kaur N	2006	GlyGen GlycoEpitope
16776550	Binding of T-antigen disaccharides to Artocarpus hirsuta lectin and jacalin are energetically different	Gaikwad SM	2006 Sep	GlyGen GlycoEpitope
17057347	Structural studies on peanut lectin complexed with disaccharides involving different linkages: further insights into the structure and interactions of the lectin	Natchiar SK	2006 Nov	GlyGen GlycoEpitope PubChem
16990264	Crystal Structure of the Galectin-9 N-terminal Carbohydrate Recognition Domain from Mus musculus Reveals the Basic Mechanism of Carbohydrate Recognition	Nagae M	2006 Nov 24	GlyGen GlycoEpitope

PubAnnotation

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Title	Authors	Source	Publication Date	PubMed ID
An activity phosphorylating tyrosine in polyoma T antigen immunoprecipitates.	Eckhart W Hutchinson MA Hunter T	Cell	1979 Dec	229973
Tumor antigens induced by nontransforming mutants of polyoma virus.	Silver J Schaffhausen B Benjamin T	Cell	1978 Oct	214241
Mapping of early SV40-specific functions by microinjection of different early viral DNA fragments.	Mueller C Graessmann A Graessmann M	Cell	1978 Oct	214244
Altered metabolism of heparan sulfate in simian virus 40 transformed cloned mouse cells.	Winterbourne DJ Mora PT	J Biol Chem	1978 Jul 25	209027

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

All Resources

Other Information

Tools

Search Tools

Guidelines

Summary

External Links

KEGG BRITE Database

GlycoEpitope

Sequence Descriptors

International Collaboration

Acknowledgements