G00033MO

Summary
GlyTouCan ID
G00033MO
IUPAC Condensed
Gal(b1-3)[GlcNAc(b1-6)]GalNAc(a1-
Motifs
O-Glycan core 2
Subsumption Level
Fully-defined saccharide
Monoisotopic Mass
586.22
GlyConnect structure
GlyGen
ChEBI
PubChem Compound
PubChem Substance
3D Structures
GlycoShape
G00033MO
Displaying 1 entry
Archetype α β
G00034MO
G00033MO
G24720OO
Organisms
Taxonomic Hierarchy
GlycoGene Database (GGDB)
Displaying all 4 entries
Gene Symbol Donor Acceptor Reducing terminal(Acceptor) Product Reducing terminal(Product) Reference
B3GALNT2 UDP-GalNAc
G00033MO
Ser/Thr
G01707KB
Ser/Thr
GCNT1 UDP-GlcNAc
G00031MO
Ser/Thr (core 2)
G00033MO
Ser/Thr (core 2)
GCNT4 UDP-GlcNAc
G00031MO
Ser/Thr
G00033MO
Ser/Thr
GCNT3 UDP-GlcNAc
G00031MO
Ser/Thr
G00033MO
Ser/Thr
Displaying entries 1 - 5 of 22 in total
Gene Symbol Donor Acceptor Reducing terminal(Acceptor) Product Reducing terminal(Product) Reference
ST3GAL1 CMP-Neu5Ac
G00033MO
O-glycan Synthesis
G85608AG
O-glycan Synthesis
FUT2 GDP-Fuc
G00033MO
O-glycan Synthesis
G32426JY
O-glycan Synthesis
B4GALT4 UDP-Gal
G00033MO
pNP
G64973KT
pNP
B4GALT1 UDP-Gal
G00033MO
O-glycan Synthesis
G64973KT
O-glycan Synthesis
B4GALNT4 UDP-GalNAc
G00033MO
[alpha]-pNP
G52144RR
[alpha]-pNP
Displaying all 4 entries
Gene Symbol Donor Acceptor Reducing terminal(Acceptor) Reference
GAL3ST3 PAPS
G00033MO
octyl
B3GNT8 UDP-GlcNAc
G00033MO
core 2-pNp
B3GNT6 UDP-GlcNAc
G00033MO
[alpha]-pNP(core 2)
B3GNT7 UDP-GlcNAc
G00033MO
core 2-pNp
KEGG BRITE Database
Sequence Descriptors
GlycoCT
RES
1b:a-dgal-HEX-1:5
2s:n-acetyl
3b:b-dgal-HEX-1:5
4b:b-dglc-HEX-1:5
5s:n-acetyl
LIN
1:1d(2+1)2n
2:1o(3+1)3d
3:1o(6+1)4d
4:4d(2+1)5n
WURCS
WURCS=2.0/3,3,2/[a2112h-1a_1-5_2*NCC/3=O][a2112h-1b_1-5][a2122h-1b_1-5_2*NCC/3=O]/1-2-3/a3-b1_a6-c1
Literature
Displaying entries 41 - 42 of 42 in total
PubMed ID Title First Author Publication Date Source
952526 Immunochemical studies on blood groups. Structures and immunochemical properties of oligosaccharides from two fractions of blood group substance from human ovarian cyst fluid differing in B, I, and i activities and reactivity toward concanavalin A McAuliffe FM 1976 Jul
  • GlyGen
4357339 Immunochemical studies on blood groups. LVII. Structures of oligosaccharides produced by base-borohydride degradation of human ovarian cyst blood group H, Leb and Lea active glycoproteins Rovis L 1973 Dec 01
  • GlyGen
PubAnnotation
Displaying entries 1 - 5 of 10 in total
Title Authors Source Publication Date PubMed ID
In-Depth Profiling of O-Glycan Isomers in Human Cells Using C18 Nanoliquid Chromatography-Mass Spectrometry and Glycogenomics.
  • de Haan N
  • Narimatsu Y
  • Koed Møller Aasted M
  • Larsen ISB
  • Marinova IN
  • Dabelsteen S
  • Vakhrushev SY
  • Wandall HH
Anal Chem 2022 Mar 15 35245040
Sulfation of O-glycans on Mucin-type Proteins From Serous Ovarian Epithelial Tumors.
  • Thomsson KA
  • Vitiazeva V
  • Mateoiu C
  • Jin C
  • Liu J
  • Holgersson J
  • Weijdegård B
  • Sundfeldt K
  • Karlsson NG
Mol Cell Proteomics 2021 34555499
Deciphering Isomers with a Multiple Reaction Monitoring Method for the Complete Detectable O-Glycan Repertoire of the Candidate Therapeutic, Lubricin.
  • Flowers SA
  • Lane CS
  • Karlsson NG
Anal Chem 2019 Aug 6 31246420
The O-glycomap of lubricin, a novel mucin responsible for joint lubrication, identified by site-specific glycopeptide analysis.
  • Ali L
  • Flowers SA
  • Jin C
  • Bennet EP
  • Ekwall AK
  • Karlsson NG
Mol Cell Proteomics 2014 Dec 25187573
Almost all human gastric mucin O-glycans harbor blood group A, B or H antigens and are potential binding sites for Helicobacter pylori.
  • Rossez Y
  • Maes E
  • Lefebvre Darroman T
  • Gosset P
  • Ecobichon C
  • Joncquel Chevalier Curt M
  • Boneca IG
  • Michalski JC
  • Robbe-Masselot C
Glycobiology 2012 Sep 22522599

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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01


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