G57321FI

Summary
GlyTouCan ID
G57321FI
IUPAC Condensed
GalNAc(a1-
Motifs
Tn antigen
GlyConnect structure
GlyGen
ChEBI
PubChem Compound
PubChem Substance
The Human Metabolome Database
3D Structures
GlycoNAVI
G57321FI
GLYCAM
DGalpNAca1-OH
GlycoShape
Organisms
Taxonomic Hierarchy
GlycoGene Database (GGDB)
Displaying all 4 entries
Gene Symbol Donor Acceptor Reducing terminal(Acceptor) Product Reducing terminal(Product) Reference
C1GALT1 (not applicable)
G57321FI
Ser/Thr
G00031MO
Ser/Thr
ST6GALNAC1 CMP-Neu5Ac
G57321FI
Ser/Thr
G36123IU
Ser/Thr
ST6GALNAC1 CMP-Neu5Ac
G57321FI
O-glycan Synthesis
G36123IU
O-glycan Synthesis
B3GNT6 UDP-GlcNAc
G57321FI
[alpha]-pNP
G00035MO
[alpha]-pNP
Displaying entries 1 - 5 of 9 in total
Gene Symbol Donor Acceptor Reducing terminal(Acceptor) Product Reducing terminal(Product) Reference
C1GALT1 (not applicable)
G57321FI
Ser/Thr
G00031MO
Ser/Thr
ST6GALNAC1 CMP-Neu5Ac
G57321FI
Ser/Thr
G36123IU
Ser/Thr
ST6GALNAC4 CMP-Neu5Ac
G57321FI
benzyl
G36123IU
benzyl
ST6GALNAC1 CMP-Neu5Ac
G57321FI
O-glycan Synthesis
G36123IU
O-glycan Synthesis
ST6GALNAC1 CMP-Neu5Ac
G57321FI
[Ala-Thr(*)-Ala]2-7
G36123IU
[Ala-Thr(*)-Ala]2-7
Displaying entries 21 - 25 of 35 in total
Gene Symbol Donor Acceptor Reducing terminal(Acceptor) Reference
B4GALNT3 UDP-GalNAc
G57321FI
[alpha]-Bz
B3GLCT UDP-Glc
G57321FI
[alpha]-Benzyl
GCNT3 UDP-GlcNAc
G57321FI
B3GNT7 UDP-GlcNAc
G57321FI
[alpha]-pNp
GCNT4 UDP-GlcNAc
G57321FI
GlycoEpitope
Epitope ID
EP0021
Pathway
Displaying entries 1 - 10 of 57 in total
Pathway Name Organism
E.coli O101 Escherichia coli
E.coli O103 Escherichia coli
E.coli O107 Escherichia coli
E.coli O112ab Escherichia coli
E.coli O112ac Escherichia coli
E.coli O116 Escherichia coli
E.coli O117 Escherichia coli
E.coli O125ab Escherichia coli
E.coli O127 Escherichia coli
E.coli O128ab-H27 Escherichia coli
Sequence Descriptors
GlycoCT
RES
1b:a-dgal-HEX-1:5
2s:n-acetyl
LIN
1:1d(2+1)2n
WURCS
WURCS=2.0/1,1,0/[a2112h-1a_1-5_2*NCC/3=O]/1/
Literature
Displaying entries 111 - 120 of 2052 in total
PubMed ID Title First Author Publication Date Source
34413198 Minimal Physiologically Based Pharmacokinetic-Pharmacodynamic (mPBPK-PD) Model of N-Acetylgalactosamine–Conjugated Small Interfering RNA Disposition and Gene Silencing in Preclinical Species and Humans Ayyar VS 2021 Nov
  • PubChem
34474100 GalNAc-siRNA conjugates: Prospective tools on the frontier of anti-viral therapeutics Thangamani L 2021 Nov
  • PubChem
34059811 The current landscape of nucleic acid therapeutics Kulkarni JA 2021 May 31
  • PubChem
34050373 Severe homocysteinemia in two givosiran-treated porphyria patients: is free heme deficiency the culprit? Petrides PE 2021 May 29
  • PubChem
33949602 The effect of deoxyfluorination and O-acylation on the cytotoxicity of N-acetyl-<scp>d</scp>-gluco- and <scp>d</scp>-galactosamine hemiacetals Hamala V 2021 May 26
  • PubChem
33950677 Syntheses of Morpholine-Based Nucleotide Analogs for Hepatic siRNA Targeting and Stabilization Hofmeister A 2021 May 05
  • PubChem
33942901 SLN124, a GalNac‐siRNA targeting transmembrane serine protease 6, in combination with deferiprone therapy reduces ineffective erythropoiesis and hepatic iron‐overload in a mouse model of β‐thalassaemia Vadolas J 2021 May 04
  • PubChem
33861472 Dysregulation of homocysteine homeostasis in acute intermittent porphyria patients receiving heme arginate or givosiran To-Figueras J 2021 May 04
  • PubChem
33792132 Sustained and targeted delivery of siRNA/DP7‐C nanoparticles from injectable thermosensitive hydrogel for hepatocellular carcinoma therapy Zhao B 2021 May 02
  • PubChem
33806155 Site-Specific O-Glycosylation Analysis of SARS-CoV-2 Spike Protein Produced in Insect and Human Cells Bagdonaite I 2021 Mar 25
  • GlyGen
  • PubChem
PubAnnotation
Displaying entries 1 - 5 of 9 in total
Title Authors Source Publication Date PubMed ID
The Quest for Anticancer Vaccines: Deciphering the Fine-Epitope Specificity of Cancer-Related Monoclonal Antibodies by Combining Microarray Screening and Saturation Transfer Difference NMR.
  • Coelho H
  • Matsushita T
  • Artigas G
  • Hinou H
  • Cañada FJ
  • Lo-Man R
  • Leclerc C
  • Cabrita EJ
  • Jiménez-Barbero J
  • Nishimura S
  • Garcia-Martín F
  • Marcelo F
J Am Chem Soc 2015 Oct 7 26366611
Single molecule study of heterotypic interactions between mucins possessing the Tn cancer antigen.
  • Haugstad KE
  • Stokke BT
  • Brewer CF
  • Gerken TA
  • Sletmoen M
Glycobiology 2015 May 25527429
Loss of Core 1-derived O-Glycans Decreases Breast Cancer Development in Mice.
  • Song K
  • Herzog BH
  • Fu J
  • Sheng M
  • Bergstrom K
  • McDaniel JM
  • Kondo Y
  • McGee S
  • Cai X
  • Li P
  • Chen H
  • Xia L
J Biol Chem 2015 Aug 14 26124270
Identification of distinct glycoforms of IgA1 in plasma from patients with immunoglobulin A (IgA) nephropathy and healthy individuals.
  • Lehoux S
  • Mi R
  • Aryal RP
  • Wang Y
  • Schjoldager KT
  • Clausen H
  • van Die I
  • Han Y
  • Chapman AB
  • Cummings RD
  • Ju T
Mol Cell Proteomics 2014 Nov 25071157
Human T cell activation results in extracellular signal-regulated kinase (ERK)-calcineurin-dependent exposure of Tn antigen on the cell surface and binding of the macrophage galactose-type lectin (MGL).
  • van Vliet SJ
  • Vuist IM
  • Lenos K
  • Tefsen B
  • Kalay H
  • García-Vallejo JJ
  • van Kooyk Y
J Biol Chem 2013 Sep 20 23918927

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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01


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Last updated: April 7, 2025