G57321FI

Summary
GlyTouCan ID
G57321FI
IUPAC Condensed
GalNAc(a1-
Motifs
Tn antigen
GlyConnect structure
GlyGen
ChEBI
PubChem Compound
PubChem Substance
The Human Metabolome Database
3D Structures
GlycoNAVI
G57321FI
GLYCAM
DGalpNAca1-OH
GlycoShape
Organisms
Taxonomic Hierarchy
GlycoGene Database (GGDB)
Displaying all 4 entries
Gene Symbol Donor Acceptor Reducing terminal(Acceptor) Product Reducing terminal(Product) Reference
C1GALT1 (not applicable)
G57321FI
Ser/Thr
G00031MO
Ser/Thr
ST6GALNAC1 CMP-Neu5Ac
G57321FI
Ser/Thr
G36123IU
Ser/Thr
ST6GALNAC1 CMP-Neu5Ac
G57321FI
O-glycan Synthesis
G36123IU
O-glycan Synthesis
B3GNT6 UDP-GlcNAc
G57321FI
[alpha]-pNP
G00035MO
[alpha]-pNP
Displaying entries 1 - 5 of 9 in total
Gene Symbol Donor Acceptor Reducing terminal(Acceptor) Product Reducing terminal(Product) Reference
C1GALT1 (not applicable)
G57321FI
Ser/Thr
G00031MO
Ser/Thr
ST6GALNAC1 CMP-Neu5Ac
G57321FI
Ser/Thr
G36123IU
Ser/Thr
ST6GALNAC4 CMP-Neu5Ac
G57321FI
benzyl
G36123IU
benzyl
ST6GALNAC1 CMP-Neu5Ac
G57321FI
O-glycan Synthesis
G36123IU
O-glycan Synthesis
ST6GALNAC1 CMP-Neu5Ac
G57321FI
[Ala-Thr(*)-Ala]2-7
G36123IU
[Ala-Thr(*)-Ala]2-7
Displaying entries 21 - 25 of 35 in total
Gene Symbol Donor Acceptor Reducing terminal(Acceptor) Reference
B4GALNT3 UDP-GalNAc
G57321FI
[alpha]-Bz
B3GLCT UDP-Glc
G57321FI
[alpha]-Benzyl
GCNT3 UDP-GlcNAc
G57321FI
B3GNT7 UDP-GlcNAc
G57321FI
[alpha]-pNp
GCNT4 UDP-GlcNAc
G57321FI
GlycoEpitope
Epitope ID
EP0021
Pathway
Displaying entries 1 - 10 of 57 in total
Pathway Name Organism
E.coli O101 Escherichia coli
E.coli O103 Escherichia coli
E.coli O107 Escherichia coli
E.coli O112ab Escherichia coli
E.coli O112ac Escherichia coli
E.coli O116 Escherichia coli
E.coli O117 Escherichia coli
E.coli O125ab Escherichia coli
E.coli O127 Escherichia coli
E.coli O128ab-H27 Escherichia coli
Sequence Descriptors
GlycoCT
RES
1b:a-dgal-HEX-1:5
2s:n-acetyl
LIN
1:1d(2+1)2n
WURCS
WURCS=2.0/1,1,0/[a2112h-1a_1-5_2*NCC/3=O]/1/
Literature
Displaying entries 121 - 130 of 2052 in total
PubMed ID Title First Author Publication Date Source
33767387 LYTACs that engage the asialoglycoprotein receptor for targeted protein degradation Ahn G 2021 Mar 25
  • PubChem
33815292 New Human Follitropin Preparations: How Glycan Structural Differences May Affect Biochemical and Biological Function and Clinical Effect Dias JA 2021 Mar 19
  • PubChem
33724805 Crystal Structure of the Carbohydrate Recognition Domain of the Human Macrophage Galactose C-Type Lectin Bound to GalNAc and the Tumor-Associated Tn Antigen Gabba A 2021 Mar 16
  • PubChem
33581419 Case report of a complicated neurologically manifesting acute porphyria treated successfully with Givosiran Steinberg T 2021 Mar 15
  • PubChem
33691403 Discovery of Bivalent GalNAc-Conjugated Betulin as a Potent ASGPR-Directed Agent against Hepatocellular Carcinoma Yamansarov EY 2021 Mar 11
  • PubChem
33658366 Architecturally complex O -glycopeptidases are customized for mucin recognition and hydrolysis Pluvinage B 2021 Mar 03
  • PubChem
33746941 Soluble N-Acetylgalactosamine-Modified Antigens Enhance Hepatocyte-Dependent Antigen Cross-Presentation and Result in Antigen-Specific CD8+ T Cell Tolerance Development Damo M 2021 Mar 03
  • PubChem
33878355 A N-acetyl-D-galactosamine-binding lectin from Amaranthus gangeticus seeds inhibits biofilm formation and Ehrlich ascites carcinoma cell growth in vivo in mice Hasan I 2021 Jun 30
  • PubChem
34184789 Homocysteine elevation in givosiran treatment: Suggested ALAS1 siRNA effect on cystathionine beta‐synthase Vassiliou D 2021 Jun 29
  • PubChem
34145602 Acute intermittent porphyria, givosiran, and homocysteine Fontanellas A 2021 Jun 22
  • PubChem
PubAnnotation
Displaying entries 1 - 5 of 9 in total
Title Authors Source Publication Date PubMed ID
The Quest for Anticancer Vaccines: Deciphering the Fine-Epitope Specificity of Cancer-Related Monoclonal Antibodies by Combining Microarray Screening and Saturation Transfer Difference NMR.
  • Coelho H
  • Matsushita T
  • Artigas G
  • Hinou H
  • Cañada FJ
  • Lo-Man R
  • Leclerc C
  • Cabrita EJ
  • Jiménez-Barbero J
  • Nishimura S
  • Garcia-Martín F
  • Marcelo F
J Am Chem Soc 2015 Oct 7 26366611
Single molecule study of heterotypic interactions between mucins possessing the Tn cancer antigen.
  • Haugstad KE
  • Stokke BT
  • Brewer CF
  • Gerken TA
  • Sletmoen M
Glycobiology 2015 May 25527429
Loss of Core 1-derived O-Glycans Decreases Breast Cancer Development in Mice.
  • Song K
  • Herzog BH
  • Fu J
  • Sheng M
  • Bergstrom K
  • McDaniel JM
  • Kondo Y
  • McGee S
  • Cai X
  • Li P
  • Chen H
  • Xia L
J Biol Chem 2015 Aug 14 26124270
Identification of distinct glycoforms of IgA1 in plasma from patients with immunoglobulin A (IgA) nephropathy and healthy individuals.
  • Lehoux S
  • Mi R
  • Aryal RP
  • Wang Y
  • Schjoldager KT
  • Clausen H
  • van Die I
  • Han Y
  • Chapman AB
  • Cummings RD
  • Ju T
Mol Cell Proteomics 2014 Nov 25071157
Human T cell activation results in extracellular signal-regulated kinase (ERK)-calcineurin-dependent exposure of Tn antigen on the cell surface and binding of the macrophage galactose-type lectin (MGL).
  • van Vliet SJ
  • Vuist IM
  • Lenos K
  • Tefsen B
  • Kalay H
  • García-Vallejo JJ
  • van Kooyk Y
J Biol Chem 2013 Sep 20 23918927

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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01


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