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G57321FI

Summary

GlyTouCan ID: G57321FI
IUPAC Condensed: GalNAc(a1-
Motifs: Tn antigen

External Links

GlyGen

G57321FI

3D Structures

GLYCAM: DGalpNAca1-OH

GlycoShape

G57321FI

Organisms

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Organisms	Evidence
Fasciola hepatica (liver fluke)	GlycoEpitope
Toxocara canis (dog roundworm)	GlycoEpitope
Echinococcus granulosus	GlycoEpitope
Oryctolagus cuniculus (rabbit)	GlyTouCan(glycome-db)
Ovis aries (sheep)	GlyTouCan(glycome-db)

Taxonomic Hierarchy

root

cellular organisms [inference]

Eukaryota (eucaryotes) [inference]

Opisthokonta [inference]

Metazoa (metazoans) [inference]

Eumetazoa [inference]

Bilateria [inference]

Protostomia [inference]

Ecdysozoa [inference]

Nematoda (roundworms) [inference]

Chromadorea [inference]

Rhabditida [inference]

Spirurina [inference]

Ascaridomorpha [inference]

Ascaridoidea [inference]

Toxocaridae [inference]

Toxocara [inference]

Toxocara canis (dog roundworm)

Rhabditina [inference]

Rhabditomorpha [inference]

Strongyloidea (lungworms) [inference]

Heligmosomidae [inference]

Nippostrongylus [inference]

Nippostrongylus brasiliensis

Rhabditoidea [inference]

Rhabditidae [inference]

Peloderinae [inference]

Caenorhabditis [inference]

Caenorhabditis elegans

Panarthropoda [inference]

Arthropoda (arthropods) [inference]

Mandibulata [inference]

Pancrustacea [inference]

Hexapoda (hexapods) [inference]

Insecta (insects) [inference]

Dicondylia [inference]

Pterygota (winged insects) [inference]

Neoptera [inference]

Endopterygota [inference]

Diptera (flies) [inference]

Brachycera [inference]

Muscomorpha [inference]

Eremoneura [inference]

Cyclorrhapha [inference]

Schizophora [inference]

Acalyptratae [inference]

Ephydroidea [inference]

Drosophilidae (pomace flies) [inference]

Drosophilinae [inference]

Drosophilini [inference]

Drosophila (fruit flies) [inference]

Sophophora [inference]

melanogaster group [inference]

melanogaster subgroup [inference]

Drosophila melanogaster (fruit fly)

Calyptratae [inference]

Oestroidea [inference]

Calliphoridae (blowflies) [inference]

Chrysomyinae [inference]

Phormini [inference]

Protophormia [inference]

Protophormia terraenovae (northern blowfly)

Crustacea (crustaceans) [inference]

Multicrustacea [inference]

Malacostraca [inference]

Eumalacostraca [inference]

Peracarida [inference]

Isopoda (pill bugs, wood lice and sea slaters) [inference]

Oniscidea (pillbugs) [inference]

Crinocheta [inference]

Armadillidae [inference]

Armadillo

Spiralia [inference]

Lophotrochozoa [inference]

Platyhelminthes (flatworms) [inference]

Cestoda (tapeworms) [inference]

Eucestoda [inference]

Cyclophyllidea [inference]

Mesocestoididae [inference]

Mesocestoides [inference]

Taeniidae [inference]

Taenia [inference]

Taenia hydatigena

Echinococcus [inference]

Echinococcus granulosus group [inference]

Echinococcus granulosus

Trematoda [inference]

Digenea (flukes) [inference]

Plagiorchiida [inference]

Echinostomata [inference]

Echinostomatoidea [inference]

Fasciolidae [inference]

Fasciola [inference]

Fasciola hepatica (liver fluke)

Deuterostomia [inference]

Chordata (chordates) [inference]

Craniata [inference]

Vertebrata (vertebrates) [inference]

Gnathostomata (jawed vertebrates) [inference]

Teleostomi [inference]

Euteleostomi (bony vertebrates) [inference]

Sarcopterygii [inference]

Dipnotetrapodomorpha [inference]

Tetrapoda (tetrapods) [inference]

Amniota (amniotes) [inference]

Mammalia (mammals) [inference]

Theria [inference]

Eutheria (placentals) [inference]

Boreoeutheria [inference]

Euarchontoglires [inference]

Glires (Rodents and rabbits) [inference]

Rodentia (rodent) [inference]

Myomorpha (mice and others) [inference]

Muroidea [inference]

Muridae [inference]

Murinae [inference]

Mus (mice) [inference]

Mus [inference]

Mus musculus (house mouse)

Rattus [inference]

Rattus norvegicus (Norway rat)

Cricetidae [inference]

Cricetinae (hamsters) [inference]

Cricetulus [inference]

Cricetulus griseus (Chinese hamster)

Lagomorpha [inference]

Leporidae (rabbits and hares) [inference]

Oryctolagus [inference]

Oryctolagus cuniculus (rabbit)

Primates [inference]

Haplorrhini [inference]

Simiiformes [inference]

Catarrhini [inference]

Hominoidea (apes) [inference]

Hominidae (great apes) [inference]

Homininae [inference]

Homo [inference]

Homo sapiens (human)

Cercopithecoidea [inference]

Cercopithecidae (Old World monkeys) [inference]

Cercopithecinae [inference]

Chlorocebus [inference]

Chlorocebus aethiops (grivet)

Macaca (macaques) [inference]

Macaca mulatta (Rhesus monkey)

Laurasiatheria [inference]

Artiodactyla (even-toed ungulates & whales) [inference]

Ruminantia [inference]

Ovis aries (sheep)

Bovinae [inference]

Bos (cattle) [inference]

Bos taurus (domestic cattle)

Fungi [inference]

Dikarya [inference]

Ascomycota (ascomycetes) [inference]

saccharomyceta [inference]

Saccharomycotina (true yeasts) [inference]

Saccharomycetes [inference]

Saccharomycetales [inference]

Saccharomycetaceae [inference]

Saccharomyces [inference]

Saccharomyces cerevisiae (brewer's yeast)

Bacteria (eubacteria) [inference]

Pseudomonadota [inference]

Gammaproteobacteria [inference]

Enterobacterales [inference]

Enterobacteriaceae [inference]

Escherichia [inference]

Escherichia coli

Pseudomonadales [inference]

Pseudomonadaceae [inference]

Pseudomonas [inference]

Pseudomonas aeruginosa group [inference]

Pseudomonas aeruginosa

Viruses [inference]

Riboviria [inference]

Orthornavirae [inference]

Pisuviricota [inference]

Pisoniviricetes [inference]

Nidovirales [inference]

Cornidovirineae [inference]

Coronaviridae [inference]

Orthocoronavirinae [inference]

Betacoronavirus [inference]

Sarbecovirus [inference]

Severe acute respiratory syndrome-related coronavirus [inference]

Severe acute respiratory syndrome coronavirus 2

Pararnavirae [inference]

Artverviricota [inference]

Revtraviricetes [inference]

Ortervirales [inference]

Retroviridae [inference]

Orthoretrovirinae [inference]

Lentivirus [inference]

Human immunodeficiency virus 1

Primate lentivirus group [inference]

unclassified Primate lentivirus group [inference]

Human immunodeficiency virus

GlycoGene Database (GGDB)

Displaying **all 4** entries
Gene Symbol	Donor	Acceptor	Reducing terminal(Acceptor)	Product	Reducing terminal(Product)	Reference
C1GALT1	(not applicable)	G57321FI	Ser/Thr	G00031MO	Ser/Thr	11677243
ST6GALNAC1	CMP-Neu5Ac	G57321FI	Ser/Thr	G36123IU	Ser/Thr	10536037
ST6GALNAC1	CMP-Neu5Ac	G57321FI	O-glycan Synthesis	G36123IU	O-glycan Synthesis
B3GNT6	UDP-GlcNAc	G57321FI	[alpha]-pNP	G00035MO	[alpha]-pNP	11821425

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Gene Symbol	Donor	Acceptor	Reducing terminal(Acceptor)	Product	Reducing terminal(Product)	Reference
C1GALT1	(not applicable)	G57321FI	Ser/Thr	G00031MO	Ser/Thr	11677243
ST6GALNAC4	CMP-Neu5Ac	G57321FI	benzyl	G36123IU	benzyl	11062056
ST6GALNAC1	CMP-Neu5Ac	G57321FI	Ser/Thr	G36123IU	Ser/Thr	10536037
ST6GALNAC1	CMP-Neu5Ac	G57321FI	O-glycan Synthesis	G36123IU	O-glycan Synthesis
ST6GALNAC1	CMP-Neu5Ac	G57321FI	[Ala-Thr(*)-Ala]2-7	G36123IU	[Ala-Thr(*)-Ala]2-7	10536037

Displaying entries **26 - 30** of 35 in total

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Gene Symbol	Donor	Acceptor	Reducing terminal(Acceptor)	Reference
B3GNT2	UDP-GlcNAc	G57321FI	[alpha]1-OBn	9892646
GCNT4	UDP-GlcNAc	G57321FI		10753916
GCNT1	UDP-GlcNAc	G57321FI	[alpha]-1-p-nitrophenyl	9988682
A4GNT	UDP-GlcNAc	G57321FI	[alpha]pNP	10430883
GCNT3	UDP-GlcNAc	G57321FI	[alpha]-1-p-nitrophenyl	9988682

Core Protein

Displaying entries **391 - 400** of **819** in total

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UniProt ID	Protein Name	Reference	Source
Q12929	Epidermal growth factor receptor kinase substrate 8	23584533	GlyGen
Q13145	BMP and activin membrane-bound inhibitor homolog	23584533 25813380	GlyGen
Q13201	Multimerin-1	28035807	GlyGen
Q13214	Semaphorin-3B	23584533	GlyGen
Q13217	DnaJ homolog subfamily C member 3	25813380	GlyGen
Q13261	Interleukin-15 receptor subunit alpha	25813380	GlyGen
Q13286	Battenin	25813380	GlyGen
Q13308	Inactive tyrosine-protein kinase 7	25813380	GlyGen
Q13433	Zinc transporter ZIP6	23584533 25813380	GlyGen
Q13438	Protein OS-9	23584533 25813380	GlyGen

Pathway

Displaying entries **1 - 10** of 57 in total

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Pathway Name	Organism
E.coli O101	Escherichia coli
E.coli O103	Escherichia coli
E.coli O107	Escherichia coli
E.coli O112ab	Escherichia coli
E.coli O112ac	Escherichia coli
E.coli O116	Escherichia coli
E.coli O117	Escherichia coli
E.coli O125ab	Escherichia coli
E.coli O127	Escherichia coli
E.coli O128ab-H27	Escherichia coli

Literature

Displaying entries **161 - 170** of **2052** in total

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PubMed ID	Title	First Author	Publication Date	Source
32081641	Deficiency of O-linked-glycosylation regulates activation of T cells and aggravates Concanavalin A-induced liver injury	Hao X	2020 Mar 30	PubChem
32096313	Randomized clinical trials towards a single‐visit cure for chronic hepatitis C: Oral GSK2878175 and injectable RG‐101 in chronic hepatitis C patients and long‐acting injectable GSK2878175 in healthy participants	Deng Y	2020 Mar 18	PubChem
32170309	Chimeric siRNAs with chemically modified pentofuranose and hexopyranose nucleotides: altritol-nucleotide (ANA) containing GalNAc–siRNA conjugates: in vitro and in vivo RNAi activity and resistance to 5′-exonuclease	Kumar P	2020 Mar 14	PubChem
31994716	Pharmacokinetics and Pharmacodynamics of the Small Interfering Ribonucleic Acid, Givosiran, in Patients With Acute Hepatic Porphyria	Agarwal S	2020 Mar 07	PubChem
32134930	Reduced expression of a rhomboid protease, EhROM1, correlates with changes in the submembrane distribution and size of the Gal/GalNAc lectin subunits in the human protozoan parasite, Entamoeba histolytica	Welter BH	2020 Mar 05	PubChem
32062176	Cellular uptake of N-acetyl-d-galactosamine-, N-acetyl-d-glucosamine- and d-mannose-containing fluorescent glycoconjugates investigated by liver intravital microscopy	Maklakova SY	2020 Mar	PubChem
32561705	Therapeutic siRNA: state of the art	Hu B	2020 Jun 19	PubChem
32521139	Givosiran — Running RNA Interference to Fight Porphyria Attacks	Gonzalez-Aseguinolaza G	2020 Jun 11	PubChem
32521132	Phase 3 Trial of RNAi Therapeutic Givosiran for Acute Intermittent Porphyria	Balwani M	2020 Jun 11	PubChem
32145269	Different kinetics for the hepatic uptake of lipid nanoparticles between the apolipoprotein E/low density lipoprotein receptor and the N-acetyl-d-galactosamine/asialoglycoprotein receptor pathway	Sato Y	2020 Jun 10	PubChem

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

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International Collaboration

Acknowledgements