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G57321FI

Summary

GlyTouCan ID: G57321FI
IUPAC Condensed: GalNAc(a1-
Motifs: Tn antigen

3D Structures

GLYCAM: DGalpNAca1-OH

GlycoShape

G57321FI

Organisms

Displaying entries **1 - 5** of 26 in total

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Organisms	Evidence
Ovis aries (sheep)	GlyTouCan(glycome-db)
Cricetulus griseus (Chinese hamster)	GlyTouCan(glycome-db)
Mus musculus (house mouse)	GlyConnectStructure GlyTouCan(glycome-db) GlycoEpitope
Bos taurus (domestic cattle)	GlyTouCan(glycome-db)
Escherichia coli	GlyTouCan(bcsdb)

Taxonomic Hierarchy

root

cellular organisms [inference]

Bacteria (eubacteria) [inference]

Pseudomonadota [inference]

Gammaproteobacteria [inference]

Enterobacterales [inference]

Enterobacteriaceae [inference]

Escherichia [inference]

Escherichia coli

Pseudomonadales [inference]

Pseudomonadaceae [inference]

Pseudomonas [inference]

Pseudomonas aeruginosa group [inference]

Pseudomonas aeruginosa

Eukaryota (eucaryotes) [inference]

Opisthokonta [inference]

Metazoa (metazoans) [inference]

Eumetazoa [inference]

Bilateria [inference]

Deuterostomia [inference]

Chordata (chordates) [inference]

Craniata [inference]

Vertebrata (vertebrates) [inference]

Gnathostomata (jawed vertebrates) [inference]

Teleostomi [inference]

Euteleostomi (bony vertebrates) [inference]

Sarcopterygii [inference]

Dipnotetrapodomorpha [inference]

Tetrapoda (tetrapods) [inference]

Amniota (amniotes) [inference]

Mammalia (mammals) [inference]

Theria [inference]

Eutheria (placentals) [inference]

Boreoeutheria [inference]

Euarchontoglires [inference]

Glires (Rodents and rabbits) [inference]

Rodentia (rodent) [inference]

Myomorpha (mice and others) [inference]

Muroidea [inference]

Muridae [inference]

Murinae [inference]

Mus (mice) [inference]

Mus [inference]

Mus musculus (house mouse)

Rattus [inference]

Rattus norvegicus (Norway rat)

Cricetidae [inference]

Cricetinae (hamsters) [inference]

Cricetulus [inference]

Cricetulus griseus (Chinese hamster)

Lagomorpha [inference]

Leporidae (rabbits and hares) [inference]

Oryctolagus [inference]

Oryctolagus cuniculus (rabbit)

Primates [inference]

Haplorrhini [inference]

Simiiformes [inference]

Catarrhini [inference]

Hominoidea (apes) [inference]

Hominidae (great apes) [inference]

Homininae [inference]

Homo [inference]

Homo sapiens (human)

Cercopithecoidea [inference]

Cercopithecidae (Old World monkeys) [inference]

Cercopithecinae [inference]

Chlorocebus [inference]

Chlorocebus aethiops (grivet)

Macaca (macaques) [inference]

Macaca mulatta (Rhesus monkey)

Laurasiatheria [inference]

Artiodactyla (even-toed ungulates & whales) [inference]

Ruminantia [inference]

Pecora [inference]

Bovidae [inference]

Bovinae [inference]

Bos (cattle) [inference]

Bos taurus (domestic cattle)

Caprinae [inference]

Ovis [inference]

Ovis aries (sheep)

Protostomia [inference]

Ecdysozoa [inference]

Panarthropoda [inference]

Arthropoda (arthropods) [inference]

Mandibulata [inference]

Pancrustacea [inference]

Crustacea (crustaceans) [inference]

Multicrustacea [inference]

Malacostraca [inference]

Eumalacostraca [inference]

Peracarida [inference]

Isopoda (pill bugs, wood lice and sea slaters) [inference]

Oniscidea (pillbugs) [inference]

Crinocheta [inference]

Armadillidae [inference]

Armadillo

Hexapoda (hexapods) [inference]

Insecta (insects) [inference]

Dicondylia [inference]

Pterygota (winged insects) [inference]

Neoptera [inference]

Endopterygota [inference]

Diptera (flies) [inference]

Brachycera [inference]

Muscomorpha [inference]

Eremoneura [inference]

Cyclorrhapha [inference]

Schizophora [inference]

Acalyptratae [inference]

Ephydroidea [inference]

Drosophilidae (pomace flies) [inference]

Drosophilinae [inference]

Drosophilini [inference]

Drosophila (fruit flies) [inference]

Sophophora [inference]

melanogaster group [inference]

melanogaster subgroup [inference]

Drosophila melanogaster (fruit fly)

Calyptratae [inference]

Oestroidea [inference]

Calliphoridae (blowflies) [inference]

Chrysomyinae [inference]

Phormini [inference]

Protophormia [inference]

Protophormia terraenovae (northern blowfly)

Nematoda (roundworms) [inference]

Chromadorea [inference]

Rhabditida [inference]

Rhabditina [inference]

Rhabditomorpha [inference]

Strongyloidea (lungworms) [inference]

Heligmosomidae [inference]

Nippostrongylus [inference]

Nippostrongylus brasiliensis

Rhabditoidea [inference]

Rhabditidae [inference]

Peloderinae [inference]

Caenorhabditis [inference]

Caenorhabditis elegans

Spirurina [inference]

Ascaridomorpha [inference]

Ascaridoidea [inference]

Toxocaridae [inference]

Toxocara [inference]

Toxocara canis (dog roundworm)

Spiralia [inference]

Lophotrochozoa [inference]

Platyhelminthes (flatworms) [inference]

Cestoda (tapeworms) [inference]

Eucestoda [inference]

Cyclophyllidea [inference]

Taeniidae [inference]

Echinococcus [inference]

Echinococcus granulosus group [inference]

Echinococcus granulosus

Taenia [inference]

Taenia hydatigena

Mesocestoididae [inference]

Mesocestoides [inference]

Trematoda [inference]

Digenea (flukes) [inference]

Plagiorchiida [inference]

Echinostomata [inference]

Echinostomatoidea [inference]

Fasciolidae [inference]

Fasciola [inference]

Fasciola hepatica (liver fluke)

Fungi [inference]

Dikarya [inference]

Ascomycota (ascomycetes) [inference]

saccharomyceta [inference]

Saccharomycotina (true yeasts) [inference]

Saccharomycetes [inference]

Saccharomycetales [inference]

Saccharomycetaceae [inference]

Saccharomyces [inference]

Saccharomyces cerevisiae (brewer's yeast)

Viruses [inference]

Riboviria [inference]

Pararnavirae [inference]

Artverviricota [inference]

Revtraviricetes [inference]

Ortervirales [inference]

Retroviridae [inference]

Orthoretrovirinae [inference]

Lentivirus [inference]

Primate lentivirus group [inference]

unclassified Primate lentivirus group [inference]

Human immunodeficiency virus

Human immunodeficiency virus 1

Orthornavirae [inference]

Pisuviricota [inference]

Pisoniviricetes [inference]

Nidovirales [inference]

Cornidovirineae [inference]

Coronaviridae [inference]

Orthocoronavirinae [inference]

Betacoronavirus [inference]

Sarbecovirus [inference]

Severe acute respiratory syndrome-related coronavirus [inference]

Severe acute respiratory syndrome coronavirus 2

GlycoGene Database (GGDB)

Displaying **all 4** entries
Gene Symbol	Donor	Acceptor	Reducing terminal(Acceptor)	Product	Reducing terminal(Product)	Reference
C1GALT1	(not applicable)	G57321FI	Ser/Thr	G00031MO	Ser/Thr	11677243
ST6GALNAC1	CMP-Neu5Ac	G57321FI	Ser/Thr	G36123IU	Ser/Thr	10536037
ST6GALNAC1	CMP-Neu5Ac	G57321FI	O-glycan Synthesis	G36123IU	O-glycan Synthesis
B3GNT6	UDP-GlcNAc	G57321FI	[alpha]-pNP	G00035MO	[alpha]-pNP	11821425

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Gene Symbol	Donor	Acceptor	Reducing terminal(Acceptor)	Product	Reducing terminal(Product)	Reference
C1GALT1	(not applicable)	G57321FI	Ser/Thr	G00031MO	Ser/Thr	11677243
ST6GALNAC1	CMP-Neu5Ac	G57321FI	Ser/Thr	G36123IU	Ser/Thr	10536037
ST6GALNAC4	CMP-Neu5Ac	G57321FI	benzyl	G36123IU	benzyl	11062056
ST6GALNAC1	CMP-Neu5Ac	G57321FI	O-glycan Synthesis	G36123IU	O-glycan Synthesis
ST6GALNAC1	CMP-Neu5Ac	G57321FI	[Ala-Thr(*)-Ala]2-7	G36123IU	[Ala-Thr(*)-Ala]2-7	10536037

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Gene Symbol	Donor	Acceptor	Reducing terminal(Acceptor)	Reference
ST6GALNAC3	CMP-Neu5Ac	G57321FI	Ser/Thr	10536037
ST6GAL2	CMP-Neu5Ac	G57321FI	para-nitrophenol	12603328
ST6GALNAC2	CMP-Neu5Ac	G57321FI	benzyl	10742600 11062056
ST6GALNAC1	CMP-Neu5Ac	G57321FI	[alpha]-Bz	10536037
ST6GALNAC2	CMP-Neu5Ac	G57321FI	Ser/Thr	10536037

KEGG BRITE Database

KEGG ID

G00023

Enzyme

Reactions

Displaying **all 4** entries
KEGG Reaction	Enzyme	Acceptor	Product
R05908	2.4.1.122	G57321FI	G00031MO
R05910	2.4.1.102 2.4.1.148	G57321FI	G00041MO
R05911	2.4.3.3	G57321FI	G36123IU
R05909	2.4.1.147	G57321FI	G00035MO

Core Protein

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UniProt ID	Protein Name	Reference	Source
Q9C002	Normal mucosa of esophagus-specific gene 1 protein	23584533	GlyGen
Q9C0B5	Palmitoyltransferase ZDHHC5	23584533	GlyGen
Q9C0D2	Centrosomal protein of 295 kDa	25813380	GlyGen
Q9GZM5	Protein YIPF3	23584533 25813380	GlyGen
Q9GZP4	PITH domain-containing protein 1	23584533	GlyGen
Q9GZZ8	Extracellular glycoprotein lacritin	23584533 25813380	GlyGen
Q9H013	Disintegrin and metalloproteinase domain-containing protein 19	23584533	GlyGen
Q9H173	Nucleotide exchange factor SIL1	23584533 25813380	GlyGen
Q9H1B5	Xylosyltransferase 2	23584533 25813380	GlyGen
Q9H1U4	Multiple epidermal growth factor-like domains protein 9	23584533	GlyGen

GlycoEpitope

Epitope ID: EP0021

Pathway

Displaying entries **11 - 20** of 57 in total

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Pathway Name	Organism
E.coli O128ac	Escherichia coli
E.coli O138	Escherichia coli
E.coli O142	Escherichia coli
E.coli O154	Escherichia coli
E.coli O157	Escherichia coli
E.coli O158ab	Escherichia coli
E.coli O166	Escherichia coli
E.coli O176	Escherichia coli
E.coli O184	Escherichia coli
E.coli O185	Escherichia coli

Sequence Descriptors

GlycoCT

RES
1b:a-dgal-HEX-1:5
2s:n-acetyl
LIN
1:1d(2+1)2n

WURCS

WURCS=2.0/1,1,0/[a2112h-1a_1-5_2*NCC/3=O]/1/

Literature

Displaying entries **451 - 460** of **2052** in total

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PubMed ID	Title	First Author	Publication Date	Source
23952769	Goblet Cell Types in Intestine of Tiger Barb and Black Tetra (Cyprinidae, Characidae: Teleostei)	Leknes IL	2013 Aug 19	PubChem
23770694	Structure and gene cluster of the O-antigen of Escherichia coli O76	Perepelov AV	2013 Aug 09	PubChem
23912186	Initiation of GalNAc-type O-glycosylation in the endoplasmic reticulum promotes cancer cell invasiveness	Gill DJ	2013 Aug 02	PubChem
23454651	Mass preparation of oligosaccharides by the hydrolysis of chondroitin sulfate polysaccharides with a subcritical water microreaction system	Yamada S	2013 Apr 19	PubChem
23584533	Precision mapping of the human O-GalNAc glycoproteome through SimpleCell technology	Steentoft C	2013 Apr 12	GlyGen PubChem
23549931	A lectin array analysis for wild-type and α-Gal-knockout pig islets versus healthy human islets	Miyagawa S	2013 Apr 03	PubChem
23554387	Targeting Hepatic Cancer Cells with PEGylated Dendrimers Displaying N‐Acetylgalactosamine and SP94 Peptide Ligands	Medina SH	2013 Apr 03	PubChem
23415086	α-Selective glycosylation affords mucin-related GalNAc amino acids and diketopiperazines active on Trypanosoma cruzi	Martins-Teixeira MB	2013 Apr 01	PubChem
23443134	Identification of O-Linked N-Acetylglucosamine (O-GlcNAc)-modified Osteoblast Proteins by Electron Transfer Dissociation Tandem Mass Spectrometry Reveals Proteins Critical for Bone Formation	Nagel AK	2013 Apr	PubChem
23399548	Enhanced Mass Spectrometric Mapping of the Human GalNAc-type O-Glycoproteome with SimpleCells	Vakhrushev SY	2013 Apr	PubChem

PubAnnotation

Displaying entries **1 - 5** of 9 in total

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Title	Authors	Source	Publication Date	PubMed ID
A newly generated functional antibody identifies Tn antigen as a novel determinant in the cancer cell-lymphatic endothelium interaction.	Danussi C Coslovi A Campa C Mucignat MT Spessotto P Uggeri F Paoletti S Colombatti A	Glycobiology	2009 Oct	19528665
Enzymatic large-scale synthesis of MUC6-Tn glycoconjugates for antitumor vaccination.	Freire T Lo-Man R Piller F Piller V Leclerc C Bay S	Glycobiology	2006 May	16449349
Cloning and characterization of a new human UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase, designated pp-GalNAc-T13, that is specifically expressed in neurons and synthesizes GalNAc alpha-serine/threonine antigen.	Zhang Y Iwasaki H Wang H Kudo T Kalka TB Hennet T Kubota T Cheng L Inaba N Gotoh M Togayachi A Guo J Hisatomi H Nakajima K Nishihara S Nakamura M Marth JD Narimatsu H	J Biol Chem	2003 Jan 3	12407114
Purification, characterization, and cDNA cloning of alpha-N-acetylgalactosamine-specific lectin from starfish, Asterina pectinifera.	Kakiuchi M Okino N Sueyoshi N Ichinose S Omori A Kawabata S Yamaguchi K Ito M	Glycobiology	2002 Feb	11886841
Pursuit of optimal carbohydrate-based anticancer vaccines: preparation of a multiantigenic unimolecular glycopeptide containing the Tn, MBr1, and Lewis(y) antigens.	Allen JR Harris CR Danishefsky SJ	J Am Chem Soc	2001 Mar 7	11456809

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

All Resources

Other Information

Tools

Search Tools

Guidelines

Summary

KEGG BRITE Database

GlycoEpitope

Sequence Descriptors

International Collaboration

Acknowledgements