Organisms | Evidence |
---|---|
Ovis aries (sheep) | |
Cricetulus griseus (Chinese hamster) | |
Mus musculus (house mouse) | |
Bos taurus (domestic cattle) | |
Escherichia coli |
Gene Symbol | Donor | Acceptor | Reducing terminal(Acceptor) | Product | Reducing terminal(Product) | Reference |
---|---|---|---|---|---|---|
C1GALT1 | (not applicable) |
|
Ser/Thr |
|
Ser/Thr | |
ST6GALNAC1 | CMP-Neu5Ac |
|
Ser/Thr |
|
Ser/Thr | |
ST6GALNAC1 | CMP-Neu5Ac |
|
O-glycan Synthesis |
|
O-glycan Synthesis | |
B3GNT6 | UDP-GlcNAc |
|
[alpha]-pNP |
|
[alpha]-pNP |
Gene Symbol | Donor | Acceptor | Reducing terminal(Acceptor) | Product | Reducing terminal(Product) | Reference |
---|---|---|---|---|---|---|
C1GALT1 | (not applicable) |
|
Ser/Thr |
|
Ser/Thr | |
ST6GALNAC1 | CMP-Neu5Ac |
|
Ser/Thr |
|
Ser/Thr | |
ST6GALNAC4 | CMP-Neu5Ac |
|
benzyl |
|
benzyl | |
ST6GALNAC1 | CMP-Neu5Ac |
|
O-glycan Synthesis |
|
O-glycan Synthesis | |
ST6GALNAC1 | CMP-Neu5Ac |
|
[Ala-Thr(*)-Ala]2-7 |
|
[Ala-Thr(*)-Ala]2-7 |
Gene Symbol | Donor | Acceptor | Reducing terminal(Acceptor) | Reference |
---|---|---|---|---|
ST6GALNAC3 | CMP-Neu5Ac |
|
Ser/Thr | |
ST6GAL2 | CMP-Neu5Ac |
|
para-nitrophenol | |
ST6GALNAC2 | CMP-Neu5Ac |
|
benzyl | |
ST6GALNAC1 | CMP-Neu5Ac |
|
[alpha]-Bz | |
ST6GALNAC2 | CMP-Neu5Ac |
|
Ser/Thr |
Pathway Name | Organism |
---|---|
E.coli O5ab | Escherichia coli |
E.coli O5ac | Escherichia coli |
E.coli O61 | Escherichia coli |
E.coli O65 | Escherichia coli |
E.coli O6H10K54 | Escherichia coli |
E.coli O6H16K15 | Escherichia coli |
E.coli O70 | Escherichia coli |
E.coli O71 | Escherichia coli |
E.coli O73ab | Escherichia coli |
E.coli O86 | Escherichia coli |
RES 1b:a-dgal-HEX-1:5 2s:n-acetyl LIN 1:1d(2+1)2n
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32033212 | The Metabolomic Signature of the Placenta in Spontaneous Preterm Birth | Elshenawy S | 2020 Feb 04 |
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31821125 | Nonclinical Safety Profile of Revusiran, a 1st-Generation GalNAc-siRNA Conjugate for Treatment of Hereditary Transthyretin-Mediated Amyloidosis | Sutherland JE | 2020 Feb 01 |
|
33295623 | Contrasting the conformational effects of α-O-GalNAc and α-O-Man glycan protein modifications and their impact on the mucin-like region of alpha-dystroglycan | Borgert A | 2020 Dec 09 |
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33275144 | High-resolution visualization and quantification of nucleic acid–based therapeutics in cells and tissues using Nanoscale secondary ion mass spectrometry (NanoSIMS) | He C | 2020 Dec 04 |
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32310329 | Comprehensive N- and O-glycosylation mapping of human coagulation factor V | Ma C | 2020 Aug |
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32808038 | Investigating the pharmacodynamic durability of GalNAc–siRNA conjugates | Brown CR | 2020 Aug 18 |
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32599652 | Single‐Dose Pharmacokinetics and Pharmacodynamics of Transthyretin Targeting N‐acetylgalactosamine–Small Interfering Ribonucleic Acid Conjugate, Vutrisiran, in Healthy Subjects | Habtemariam BA | 2020 Aug 13 |
|
32297877 | Core 1 O-N-acetylgalactosamine (O-GalNAc) glycosylation in the human cell nucleus | Cejas RB | 2020 Aug 11 |
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32592692 | Delivery of Oligonucleotides to the Liver with GalNAc: From Research to Registered Therapeutic Drug | Debacker AJ | 2020 Aug 05 |
|
32417172 | O-linked N-acetylgalactosamine modification is present on the tumor suppressor p53 | Xu Z | 2020 Aug |
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Immunological response from an entirely carbohydrate antigen: design of synthetic vaccines based on Tn-PS A1 conjugates. |
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J Am Chem Soc | 2009 Jul 22 | 19552408 |
Two different glycosyltransferase defects that result in GalNAc alpha-O-peptide (Tn) expression. |
|
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Localization of O-glycan initiation, sphingomyelin synthesis, and glucosylceramide synthesis in Vero cells with respect to the endoplasmic reticulum-Golgi intermediate compartment. |
|
J Biol Chem | 1994 Feb 11 | 8307959 |
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|
Glycobiology | 1994 Aug | 7827404 |
GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.
Supported by JST NBDC Grant Number JPMJND2204
Partly supported by NIH Common Fund Grant #1U01GM125267-01
This work is licensed under Creative Commons Attribution 4.0 International
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