GlyCosmos Portal

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Organisms	Evidence
Ovis aries (sheep)	GlyTouCan(glycome-db)
Cricetulus griseus (Chinese hamster)	GlyTouCan(glycome-db)
Mus musculus (house mouse)	GlyConnectStructure GlyTouCan(glycome-db) GlycoEpitope
Bos taurus (domestic cattle)	GlyTouCan(glycome-db)
Escherichia coli	GlyTouCan(bcsdb)

Taxonomic Hierarchy

root

cellular organisms [inference]

Bacteria (eubacteria) [inference]

Pseudomonadota [inference]

Gammaproteobacteria [inference]

Enterobacterales [inference]

Enterobacteriaceae [inference]

Escherichia [inference]

Escherichia coli

Pseudomonadales [inference]

Pseudomonadaceae [inference]

Pseudomonas [inference]

Pseudomonas aeruginosa group [inference]

Pseudomonas aeruginosa

Eukaryota (eucaryotes) [inference]

Opisthokonta [inference]

Metazoa (metazoans) [inference]

Eumetazoa [inference]

Bilateria [inference]

Deuterostomia [inference]

Chordata (chordates) [inference]

Craniata [inference]

Vertebrata (vertebrates) [inference]

Gnathostomata (jawed vertebrates) [inference]

Teleostomi [inference]

Euteleostomi (bony vertebrates) [inference]

Sarcopterygii [inference]

Dipnotetrapodomorpha [inference]

Tetrapoda (tetrapods) [inference]

Amniota (amniotes) [inference]

Mammalia (mammals) [inference]

Theria [inference]

Eutheria (placentals) [inference]

Boreoeutheria [inference]

Euarchontoglires [inference]

Glires (Rodents and rabbits) [inference]

Rodentia (rodent) [inference]

Myomorpha (mice and others) [inference]

Muroidea [inference]

Muridae [inference]

Murinae [inference]

Mus (mice) [inference]

Mus [inference]

Mus musculus (house mouse)

Rattus [inference]

Rattus norvegicus (Norway rat)

Cricetidae [inference]

Cricetinae (hamsters) [inference]

Cricetulus [inference]

Cricetulus griseus (Chinese hamster)

Lagomorpha [inference]

Leporidae (rabbits and hares) [inference]

Oryctolagus [inference]

Oryctolagus cuniculus (rabbit)

Primates [inference]

Haplorrhini [inference]

Simiiformes [inference]

Catarrhini [inference]

Hominoidea (apes) [inference]

Hominidae (great apes) [inference]

Homininae [inference]

Homo [inference]

Homo sapiens (human)

Cercopithecoidea [inference]

Cercopithecidae (Old World monkeys) [inference]

Cercopithecinae [inference]

Chlorocebus [inference]

Chlorocebus aethiops (grivet)

Macaca (macaques) [inference]

Macaca mulatta (Rhesus monkey)

Laurasiatheria [inference]

Artiodactyla (even-toed ungulates & whales) [inference]

Ruminantia [inference]

Pecora [inference]

Bovidae [inference]

Bovinae [inference]

Bos (cattle) [inference]

Bos taurus (domestic cattle)

Caprinae [inference]

Ovis [inference]

Ovis aries (sheep)

Protostomia [inference]

Ecdysozoa [inference]

Panarthropoda [inference]

Arthropoda (arthropods) [inference]

Mandibulata [inference]

Pancrustacea [inference]

Crustacea (crustaceans) [inference]

Multicrustacea [inference]

Malacostraca [inference]

Eumalacostraca [inference]

Peracarida [inference]

Isopoda (pill bugs, wood lice and sea slaters) [inference]

Oniscidea (pillbugs) [inference]

Crinocheta [inference]

Armadillidae [inference]

Armadillo

Hexapoda (hexapods) [inference]

Insecta (insects) [inference]

Dicondylia [inference]

Pterygota (winged insects) [inference]

Neoptera [inference]

Endopterygota [inference]

Diptera (flies) [inference]

Brachycera [inference]

Muscomorpha [inference]

Eremoneura [inference]

Cyclorrhapha [inference]

Schizophora [inference]

Acalyptratae [inference]

Ephydroidea [inference]

Drosophilidae (pomace flies) [inference]

Drosophilinae [inference]

Drosophilini [inference]

Drosophila (fruit flies) [inference]

Sophophora [inference]

melanogaster group [inference]

melanogaster subgroup [inference]

Drosophila melanogaster (fruit fly)

Calyptratae [inference]

Oestroidea [inference]

Calliphoridae (blowflies) [inference]

Chrysomyinae [inference]

Phormini [inference]

Protophormia [inference]

Protophormia terraenovae (northern blowfly)

Nematoda (roundworms) [inference]

Chromadorea [inference]

Rhabditida [inference]

Rhabditina [inference]

Rhabditomorpha [inference]

Strongyloidea (lungworms) [inference]

Heligmosomidae [inference]

Nippostrongylus [inference]

Nippostrongylus brasiliensis

Rhabditoidea [inference]

Rhabditidae [inference]

Peloderinae [inference]

Caenorhabditis [inference]

Caenorhabditis elegans

Spirurina [inference]

Ascaridomorpha [inference]

Ascaridoidea [inference]

Toxocaridae [inference]

Toxocara [inference]

Toxocara canis (dog roundworm)

Spiralia [inference]

Lophotrochozoa [inference]

Platyhelminthes (flatworms) [inference]

Cestoda (tapeworms) [inference]

Eucestoda [inference]

Cyclophyllidea [inference]

Taeniidae [inference]

Echinococcus [inference]

Echinococcus granulosus group [inference]

Echinococcus granulosus

Taenia [inference]

Taenia hydatigena

Mesocestoididae [inference]

Mesocestoides [inference]

Trematoda [inference]

Digenea (flukes) [inference]

Plagiorchiida [inference]

Echinostomata [inference]

Echinostomatoidea [inference]

Fasciolidae [inference]

Fasciola [inference]

Fasciola hepatica (liver fluke)

Fungi [inference]

Dikarya [inference]

Ascomycota (ascomycetes) [inference]

saccharomyceta [inference]

Saccharomycotina (true yeasts) [inference]

Saccharomycetes [inference]

Saccharomycetales [inference]

Saccharomycetaceae [inference]

Saccharomyces [inference]

Saccharomyces cerevisiae (brewer's yeast)

Viruses [inference]

Riboviria [inference]

Pararnavirae [inference]

Artverviricota [inference]

Revtraviricetes [inference]

Ortervirales [inference]

Retroviridae [inference]

Orthoretrovirinae [inference]

Lentivirus [inference]

Primate lentivirus group [inference]

unclassified Primate lentivirus group [inference]

Human immunodeficiency virus

Human immunodeficiency virus 1

Orthornavirae [inference]

Pisuviricota [inference]

Pisoniviricetes [inference]

Nidovirales [inference]

Cornidovirineae [inference]

Coronaviridae [inference]

Orthocoronavirinae [inference]

Betacoronavirus [inference]

Sarbecovirus [inference]

Severe acute respiratory syndrome-related coronavirus [inference]

Severe acute respiratory syndrome coronavirus 2

GlycoGene Database (GGDB)

Displaying **all 4** entries
Gene Symbol	Donor	Acceptor	Reducing terminal(Acceptor)	Product	Reducing terminal(Product)	Reference
C1GALT1	(not applicable)	G57321FI	Ser/Thr	G00031MO	Ser/Thr	11677243
ST6GALNAC1	CMP-Neu5Ac	G57321FI	Ser/Thr	G36123IU	Ser/Thr	10536037
ST6GALNAC1	CMP-Neu5Ac	G57321FI	O-glycan Synthesis	G36123IU	O-glycan Synthesis
B3GNT6	UDP-GlcNAc	G57321FI	[alpha]-pNP	G00035MO	[alpha]-pNP	11821425

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Gene Symbol	Donor	Acceptor	Reducing terminal(Acceptor)	Product	Reducing terminal(Product)	Reference
C1GALT1	(not applicable)	G57321FI	Ser/Thr	G00031MO	Ser/Thr	11677243
ST6GALNAC1	CMP-Neu5Ac	G57321FI	Ser/Thr	G36123IU	Ser/Thr	10536037
ST6GALNAC4	CMP-Neu5Ac	G57321FI	benzyl	G36123IU	benzyl	11062056
ST6GALNAC1	CMP-Neu5Ac	G57321FI	O-glycan Synthesis	G36123IU	O-glycan Synthesis
ST6GALNAC1	CMP-Neu5Ac	G57321FI	[Ala-Thr(*)-Ala]2-7	G36123IU	[Ala-Thr(*)-Ala]2-7	10536037

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Gene Symbol	Donor	Acceptor	Reducing terminal(Acceptor)	Reference
ST6GALNAC3	CMP-Neu5Ac	G57321FI	Ser/Thr	10536037
ST6GAL2	CMP-Neu5Ac	G57321FI	para-nitrophenol	12603328
ST6GALNAC2	CMP-Neu5Ac	G57321FI	benzyl	10742600 11062056
ST6GALNAC1	CMP-Neu5Ac	G57321FI	[alpha]-Bz	10536037
ST6GALNAC2	CMP-Neu5Ac	G57321FI	Ser/Thr	10536037

KEGG BRITE Database

KEGG ID

G00023

Enzyme

Reactions

Displaying **all 4** entries
KEGG Reaction	Enzyme	Acceptor	Product
R05909	2.4.1.147	G57321FI	G00035MO
R05908	2.4.1.122	G57321FI	G00031MO
R05911	2.4.3.3	G57321FI	G36123IU
R05910	2.4.1.102 2.4.1.148	G57321FI	G00041MO

Core Protein

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UniProt ID	Protein Name	Reference	Source
A1A5C7	Solute carrier family 22 member 23	23584533	GlyGen
A1L4H1	Soluble scavenger receptor cysteine-rich domain-containing protein SSC5D	23584533	GlyGen
A6NH11	Glycolipid transfer protein domain-containing protein 2	23584533	GlyGen
A6NLU5	V-set and transmembrane domain-containing protein 2B	23584533	GlyGen
C9J069	Apical junction component 1 homolog	23584533 25813380	GlyGen
C9JH25	Proline-rich transmembrane protein 4	23584533	GlyGen
D9N008	Epiglycanin	1125949 115878	GlyConnect
O00151	PDZ and LIM domain protein 1	23584533	GlyGen
O00220	Tumor necrosis factor receptor superfamily member 10A	23584533 25813380	GlyGen
O00238	Bone morphogenetic protein receptor type-1B	23584533	GlyGen

GlycoEpitope

Epitope ID: EP0021

Pathway

Displaying entries **31 - 40** of 57 in total

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Pathway Name	Organism
E.coli O86H2K2	Escherichia coli
E.coli O86H2K62	Escherichia coli
E.coli O90	Escherichia coli
Ficolins bind to repetitive carbohydrate structures on the target cell surface	Xenopus tropicalis
Ficolins bind to repetitive carbohydrate structures on the target cell surface	Homo sapiens
Ficolins bind to repetitive carbohydrate structures on the target cell surface	Gallus gallus
Ficolins bind to repetitive carbohydrate structures on the target cell surface	Mus musculus
Ficolins bind to repetitive carbohydrate structures on the target cell surface	Rattus norvegicus
Ficolins bind to repetitive carbohydrate structures on the target cell surface	Bos taurus
Ficolins bind to repetitive carbohydrate structures on the target cell surface	Canis familiaris

Sequence Descriptors

GlycoCT

RES
1b:a-dgal-HEX-1:5
2s:n-acetyl
LIN
1:1d(2+1)2n

WURCS

WURCS=2.0/1,1,0/[a2112h-1a_1-5_2*NCC/3=O]/1/

Literature

Displaying entries **31 - 40** of **2052** in total

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PubMed ID	Title	First Author	Publication Date	Source
38348876	A combinatorial approach for achieving CNS-selective RNAi	Ferguson CM	2024 Feb 13	PubChem
38227794	Safety and Tolerability of GalNAc3-Conjugated Antisense Drugs Compared to the Same-Sequence 2′-O-Methoxyethyl-Modified Antisense Drugs: Results from an Integrated Assessment of Phase 1 Clinical Trial Data	Baker BF	2024 Feb 01	PubChem
39177802	Givosiran for the Treatment of Pediatric Acute Intermittent Porphyria	Bujold KE	2024 Aug 22	PubChem
39126245	O-GlcNAcylation determines the function of the key O-GalNAc glycosyltransferase C1GalT1 in bladder cancer	Jiang Y	2024 Aug 01	PubChem
38667801	Chemical Synthesis of Fucosylated Chondroitin Sulfate Tetrasaccharide with Fucosyl Branch at the 6-OH of GalNAc Residue	Lv C	2024 Apr 19	PubChem
38479165	Research progress on asialoglycoprotein receptor-targeted radiotracers designed for hepatic nuclear medicine imaging	Hua Y	2024 Apr 05	PubChem
38570436	Cross-Reactive Polyclonal Antibodies Raised Against GalNAc-Conjugated siRNA Recognize Mostly the GalNAc Moiety	Ballman KK	2024 Apr 03	PubChem
38708485	Recovery of chronic motor neuropathy due to acute intermittent porphyria after givosiran treatment in a young boy: a case report	Mazzoli M	2024 Apr	PubChem
38401583	Deficiency of polypeptide N-acetylgalactosamine transferase 9 contributes to a risk for Parkinson's disease via mitochondrial dysfunctions	Peng Y	2024 Apr	PubChem
38995536	Integrating HexNAcQuest with Glycoproteomics Data Analysis Software to Distinguish HexNAc Isomers on Peptides	Hou C	2024	PubChem

PubAnnotation

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Title	Authors	Source	Publication Date	PubMed ID
Immunological response from an entirely carbohydrate antigen: design of synthetic vaccines based on Tn-PS A1 conjugates.	De Silva RA Wang Q Chidley T Appulage DK Andreana PR	J Am Chem Soc	2009 Jul 22	19552408
Two different glycosyltransferase defects that result in GalNAc alpha-O-peptide (Tn) expression.	King MJ Chan A Roe R Warren BF Dell A Morris HR Bartolo DC Durdey P Corfield AP	Glycobiology	1994 Jun	7949653
Localization of O-glycan initiation, sphingomyelin synthesis, and glucosylceramide synthesis in Vero cells with respect to the endoplasmic reticulum-Golgi intermediate compartment.	Schweizer A Clausen H van Meer G Hauri HP	J Biol Chem	1994 Feb 11	8307959
Carbohydrate receptor-mediated gene transfer to human T leukaemic cells.	Thurnher M Wagner E Clausen H Mechtler K Rusconi S Dinter A Birnstiel ML Berger EG Cotten M	Glycobiology	1994 Aug	7827404

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

All Resources

Other Information

Tools

Search Tools

Guidelines

Summary

External Links

KEGG BRITE Database

GlycoEpitope

Sequence Descriptors

International Collaboration

Acknowledgements