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GlyTouCan
Glycan Structure Repository
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Glycoconjugate Repository
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Glycomics MS raw data Repository
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Glycomics MS Repository for glycan annotations from GlycoWorkbench
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Repository for lectin-assisted multimodality data
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G57321FI
Summary
- GlyTouCan ID
-
G57321FI
- IUPAC Condensed
- GalNAc(a1-
- Motifs
- Tn antigen
Organisms
| Organisms | Evidence |
|---|---|
| Ovis aries (sheep) | |
| Cricetulus griseus (Chinese hamster) | |
| Mus musculus (house mouse) | |
| Bos taurus (domestic cattle) | |
| Escherichia coli |
Taxonomic Hierarchy
root
cellular organisms [inference]
Eukaryota (eucaryotes) [inference]
Opisthokonta [inference]
Metazoa (metazoans) [inference]
GlycoGene Database (GGDB)
| Gene Symbol | Donor | Acceptor | Reducing terminal(Acceptor) | Product | Reducing terminal(Product) | Reference |
|---|---|---|---|---|---|---|
| C1GALT1 | (not applicable) |
G57321FI
|
Ser/Thr |
G00031MO
|
Ser/Thr | |
| ST6GALNAC1 | CMP-Neu5Ac |
G57321FI
|
Ser/Thr |
G36123IU
|
Ser/Thr | |
| ST6GALNAC1 | CMP-Neu5Ac |
G57321FI
|
O-glycan Synthesis |
G36123IU
|
O-glycan Synthesis | |
| B3GNT6 | UDP-GlcNAc |
G57321FI
|
[alpha]-pNP |
G00035MO
|
[alpha]-pNP |
| Gene Symbol | Donor | Acceptor | Reducing terminal(Acceptor) | Product | Reducing terminal(Product) | Reference |
|---|---|---|---|---|---|---|
| C1GALT1 | (not applicable) |
G57321FI
|
Ser/Thr |
G00031MO
|
Ser/Thr | |
| ST6GALNAC1 | CMP-Neu5Ac |
G57321FI
|
Ser/Thr |
G36123IU
|
Ser/Thr | |
| ST6GALNAC4 | CMP-Neu5Ac |
G57321FI
|
benzyl |
G36123IU
|
benzyl | |
| ST6GALNAC1 | CMP-Neu5Ac |
G57321FI
|
O-glycan Synthesis |
G36123IU
|
O-glycan Synthesis | |
| ST6GALNAC1 | CMP-Neu5Ac |
G57321FI
|
[Ala-Thr(*)-Ala]2-7 |
G36123IU
|
[Ala-Thr(*)-Ala]2-7 |
| Gene Symbol | Donor | Acceptor | Reducing terminal(Acceptor) | Reference |
|---|---|---|---|---|
| ST6GALNAC3 | CMP-Neu5Ac |
G57321FI
|
Ser/Thr | |
| ST6GAL2 | CMP-Neu5Ac |
G57321FI
|
para-nitrophenol | |
| ST6GALNAC2 | CMP-Neu5Ac |
G57321FI
|
benzyl | |
| ST6GALNAC1 | CMP-Neu5Ac |
G57321FI
|
[alpha]-Bz | |
| ST6GALNAC2 | CMP-Neu5Ac |
G57321FI
|
Ser/Thr |
KEGG BRITE Database
G00041MO
Core Protein
| UniProt ID | Protein Name | Reference | Source |
|---|---|---|---|
| O43660 | Pleiotropic regulator 1 | ||
| O43674 | NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 5, mitochondrial | ||
| O43760 | Synaptogyrin-2 | ||
| O43768 | Alpha-endosulfine | ||
| O43852 | Calumenin | ||
| O43854 | EGF-like repeat and discoidin I-like domain-containing protein 3 | ||
| O43909 | Exostosin-like 3 | ||
| O60279 | Sushi domain-containing protein 5 | ||
| O60309 | Leucine-rich repeat-containing protein 37A3 | ||
| O60353 | Frizzled-6 |
GlycoEpitope
- Epitope ID
- EP0021
Pathway
| Pathway Name | Organism |
|---|---|
| Ficolins bind to repetitive carbohydrate structures on the target cell surface | Sus scrofa |
| Initial triggering of complement | Mus musculus |
| Initial triggering of complement | Gallus gallus |
| Initial triggering of complement | Xenopus tropicalis |
| Initial triggering of complement | Sus scrofa |
| Initial triggering of complement | Bos taurus |
| Initial triggering of complement | Canis familiaris |
| Initial triggering of complement | Rattus norvegicus |
| Initial triggering of complement | Homo sapiens |
| Lectin pathway of complement activation | Bos taurus |
Sequence Descriptors
- GlycoCT
-
RES 1b:a-dgal-HEX-1:5 2s:n-acetyl LIN 1:1d(2+1)2n
- WURCS
- WURCS=2.0/1,1,0/[a2112h-1a_1-5_2*NCC/3=O]/1/
Literature
| PubMed ID | Title | First Author | Publication Date | Source |
|---|---|---|---|---|
| 28087069 | Safety, tolerability, and antiviral effect of RG-101 in patients with chronic hepatitis C: a phase 1B, double-blind, randomised controlled trial | van der Ree MH | 2017 Feb 18 |
|
| 28158620 | Characterizing the effect of GalNAc and phosphorothioate backbone on binding of antisense oligonucleotides to the asialoglycoprotein receptor | Schmidt K | 2017 Feb 03 |
|
| 27973758 | Structural analysis and unique molecular recognition properties of a Bauhinia forficata lectin that inhibits cancer cell growth | Lubkowski J | 2017 Feb |
|
| 27984144 | Lectin from seeds of a Brazilian lima bean variety (Phaseolus lunatus L. var. cascavel) presents antioxidant, antitumour and gastroprotective activities | e Lacerda RR | 2017 Feb |
|
| 29046357 | Structural and thermodynamic analyses reveal critical features of glycopeptide recognition by the human PILRα immune cell receptor | Furukawa A | 2017 Dec 22 |
|
| 29166012 | The Use of Fluoroproline in MUC1 Antigen Enables Efficient Detection of Antibodies in Patients with Prostate Cancer | Somovilla VJ | 2017 Dec 12 |
|
| 29208955 | The interdomain flexible linker of the polypeptide GalNAc transferases dictates their long-range glycosylation preferences | de las Rivas M | 2017 Dec 05 |
|
| 29193962 | Cell Penetrating Polymers Containing Guanidinium Trigger Apoptosis in Human Hepatocellular Carcinoma Cells unless Conjugated to a Targeting N-Acetyl-Galactosamine Block | Tan Z | 2017 Dec 01 |
|
| 28526733 | Discovery and Optimization of HKT288, a Cadherin-6–Targeting ADC for the Treatment of Ovarian and Renal Cancers | Bialucha CU | 2017 Aug 31 |
|
| 28809818 | Synthesis of 5′-GalNAc-Conjugated Oligonucleotides: A Comparison of Solid and Solution-Phase Conjugation Strategies | Cedillo I | 2017 Aug 15 |
|
PubAnnotation
