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MIRAGE
G57321FI

Summary
GlyTouCan ID
G57321FI
IUPAC Condensed
GalNAc(a1-
Motifs
Tn antigen
GlyConnect structure
GlyGen
ChEBI
PubChem Compound
PubChem Substance
The Human Metabolome Database
3D Structures
GLYCAM
DGalpNAca1-OH
GlycoShape
G57321FI
Organisms
Displaying entries 1 - 5 of 26 in total
Organisms Evidence
Ovis aries (sheep)
Cricetulus griseus (Chinese hamster)
Mus musculus (house mouse)
Bos taurus (domestic cattle)
Escherichia coli
Taxonomic Hierarchy
GlycoGene Database (GGDB)
Displaying all 4 entries
Gene Symbol Donor Acceptor Reducing terminal(Acceptor) Product Reducing terminal(Product) Reference
C1GALT1 (not applicable)
G57321FI
Ser/Thr
G00031MO
Ser/Thr
ST6GALNAC1 CMP-Neu5Ac
G57321FI
Ser/Thr
G36123IU
Ser/Thr
ST6GALNAC1 CMP-Neu5Ac
G57321FI
O-glycan Synthesis
G36123IU
O-glycan Synthesis
B3GNT6 UDP-GlcNAc
G57321FI
[alpha]-pNP
G00035MO
[alpha]-pNP
Displaying entries 1 - 5 of 9 in total
Gene Symbol Donor Acceptor Reducing terminal(Acceptor) Product Reducing terminal(Product) Reference
C1GALT1 (not applicable)
G57321FI
Ser/Thr
G00031MO
Ser/Thr
ST6GALNAC1 CMP-Neu5Ac
G57321FI
Ser/Thr
G36123IU
Ser/Thr
ST6GALNAC4 CMP-Neu5Ac
G57321FI
benzyl
G36123IU
benzyl
ST6GALNAC1 CMP-Neu5Ac
G57321FI
O-glycan Synthesis
G36123IU
O-glycan Synthesis
ST6GALNAC1 CMP-Neu5Ac
G57321FI
[Ala-Thr(*)-Ala]2-7
G36123IU
[Ala-Thr(*)-Ala]2-7
Displaying entries 1 - 5 of 35 in total
Gene Symbol Donor Acceptor Reducing terminal(Acceptor) Reference
ST6GALNAC3 CMP-Neu5Ac
G57321FI
Ser/Thr
ST6GAL2 CMP-Neu5Ac
G57321FI
para-nitrophenol
ST6GALNAC2 CMP-Neu5Ac
G57321FI
benzyl
ST6GALNAC1 CMP-Neu5Ac
G57321FI
[alpha]-Bz
ST6GALNAC2 CMP-Neu5Ac
G57321FI
Ser/Thr
KEGG BRITE Database
KEGG ID
Enzyme
Reactions
Displaying all 4 entries
KEGG Reaction Enzyme Acceptor Product
R05908
R05910
R05911
R05909
Core Protein
Displaying entries 591 - 600 of 819 in total
UniProt ID Protein Name Reference Source
Q8NFL0 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 7
Q8NFT8 Delta and Notch-like epidermal growth factor-related receptor
Q8NFY4 Semaphorin-6D
Q8NI22 Multiple coagulation factor deficiency protein 2
Q8NI32 Ly6/PLAUR domain-containing protein 6B
Q8NI99 Angiopoietin-related protein 6
Q8TAT2 Fibroblast growth factor-binding protein 3
Q8TAX7 Mucin-7
Q8TBF5 Phosphatidylinositol-glycan biosynthesis class X protein
Q8TCZ2 CD99 antigen-like protein 2
GlycoEpitope
Epitope ID
EP0021
Pathway
Displaying entries 51 - 57 of 57 in total
Pathway Name Organism
Lectin pathway of complement activation Bos taurus
Lectin pathway of complement activation Rattus norvegicus
Lectin pathway of complement activation Mus musculus
Lectin pathway of complement activation Homo sapiens
Lectin pathway of complement activation Xenopus tropicalis
Lectin pathway of complement activation Gallus gallus
Lectin pathway of complement activation Canis familiaris
Sequence Descriptors
GlycoCT
RES
1b:a-dgal-HEX-1:5
2s:n-acetyl
LIN
1:1d(2+1)2n
WURCS
WURCS=2.0/1,1,0/[a2112h-1a_1-5_2*NCC/3=O]/1/
Literature
Displaying entries 711 - 720 of 2052 in total
PubMed ID Title First Author Publication Date Source
16525726 The influence of N- and O-glycosylation inhibitors on the glycosylation profile of cellular membrane proteins and adhesive properties of carcinoma cell lines Paszkiewicz-Gadek A 2006 Apr
  • GlyGen
  • GlycoEpitope
16624894 N-Acetylgalactosamine 4,6-O-sulfate residues mediate binding and activation of heparin cofactor II by porcine mucosal dermatan sulfate Halldórsdóttir AM 2006 Apr 19
  • PubChem
16615117 Interference with O-glycosylation in RMA lymphoma cells leads to a reduced in vivo growth of the tumor Chen L 2006 Apr 13
  • GlyGen
  • GlycoEpitope
  • PubChem
16609676 Pathogenic IgA in IgA nephropathy: still the blind men and the elephant? Lai KN 2006 Apr
  • PubChem
15864746 Polyvalent GalNAcalpha1-->Ser/Thr (Tn) and Galbeta1-->3GalNAcalpha1-->Ser/Thr (T alpha) as the most potent recognition factors involved in Maclura pomifera agglutinin-glycan interactions Wu AM 2005
  • GlyGen
  • GlycoEpitope
15864747 Further characterization of the binding properties of two monoclonal antibodies recognizing human Tn red blood cells Wua AM 2005
  • GlyGen
  • GlycoEpitope
15864748 Lectinochemical studies on the glyco-recognition factors of a Tn (GalNAcalpha1-->Ser/Thr) specific lectin isolated from the seeds of Salvia sclarea Wu AM 2005
  • GlyGen
  • GlycoEpitope
16006554 The Molecular Architecture of Human N-Acetylgalactosamine Kinase Thoden JB 2005 Sep 23
  • PubChem
16174741 Distinct functional units of the Golgi complex in Drosophila cells Yano H 2005 Sep 20
  • GlyGen
  • GlycoEpitope
16297170 The glycans deficiencies of macromolecular IgA1 is a contributory factor of variable pathological phenotypes of IgA nephropathy Xu LX 2005 Sep 11
  • PubChem
PubAnnotation
Displaying entries 1 - 5 of 9 in total
Title Authors Source Publication Date PubMed ID
A newly generated functional antibody identifies Tn antigen as a novel determinant in the cancer cell-lymphatic endothelium interaction.
  • Danussi C
  • Coslovi A
  • Campa C
  • Mucignat MT
  • Spessotto P
  • Uggeri F
  • Paoletti S
  • Colombatti A
 Glycobiology 2009 Oct 19528665
Enzymatic large-scale synthesis of MUC6-Tn glycoconjugates for antitumor vaccination.
  • Freire T
  • Lo-Man R
  • Piller F
  • Piller V
  • Leclerc C
  • Bay S
 Glycobiology 2006 May 16449349
Cloning and characterization of a new human UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase, designated pp-GalNAc-T13, that is specifically expressed in neurons and synthesizes GalNAc alpha-serine/threonine antigen.
  • Zhang Y
  • Iwasaki H
  • Wang H
  • Kudo T
  • Kalka TB
  • Hennet T
  • Kubota T
  • Cheng L
  • Inaba N
  • Gotoh M
  • Togayachi A
  • Guo J
  • Hisatomi H
  • Nakajima K
  • Nishihara S
  • Nakamura M
  • Marth JD
  • Narimatsu H
 J Biol Chem 2003 Jan 3 12407114
Purification, characterization, and cDNA cloning of alpha-N-acetylgalactosamine-specific lectin from starfish, Asterina pectinifera.
  • Kakiuchi M
  • Okino N
  • Sueyoshi N
  • Ichinose S
  • Omori A
  • Kawabata S
  • Yamaguchi K
  • Ito M
 Glycobiology 2002 Feb 11886841
Pursuit of optimal carbohydrate-based anticancer vaccines: preparation of a multiantigenic unimolecular glycopeptide containing the Tn, MBr1, and Lewis(y) antigens.
  • Allen JR
  • Harris CR
  • Danishefsky SJ
 J Am Chem Soc 2001 Mar 7 11456809
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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: August 4, 2025